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San Francisco 49ers defensive end Nick Bosa (hip) and left tackle Trent Williams (ankle) were both absent from practice on Thursday for the second straight day this week. It's bad news for the team's defensive and offensive-line standouts in terms of their availability for the upcoming game on Sunday versus the Green Bay Packers. The 27-year-old Bosa is pretty banged up right now and will need to return to practice on Friday to have a shot at playing in Week 12. The same can be said for Williams, who came out of the Week 11 loss to the division-rival Seattle Seahawks with soreness related to a nagging ankle injury. Both Bosa and Williams were questionable to play last week, but this week they could be held out entirely. Fantasy managers in IDP leagues should have a backup D-lineman in place in case Bosa is ruled out on Friday.--Keith Hernandez - RotoBaller
Source: ESPN.com - Nick Wagoner
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