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13 seconds agoThe San Francisco 49ers placed running back Jordan Mason (ankle) on Injured Reserve on Monday after he suffered a high-ankle sprain in the Sunday night loss to the Buffalo Bills. It means that Mason will miss at least the next four games and won't be eligible to return until the Week 18 regular-season finale on the road against the division-rival Arizona Cardinals. With fantasy championships typically coming in Week 17, managers now won't have a reason to hold onto Mason in single-year leagues. Christian McCaffrey (knee) also suffered a PCL injury in the snow on Sunday night and is facing a six-week recovery, so his season is likely over. It all means that fantasy managers in need at RB should make rookie Isaac Guerendo their top waiver-wire priority heading into Week 14. Guerendo should now lead San Fran's backfield, with Patrick Taylor also getting involved.--Keith Hernandez - RotoBaller
Source: ESPN.com - Nick Wagoner

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REAL-TIME FANTASY NEWS

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