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The Indianapolis Colts officially ruled out running back Jonathan Taylor (ankle) for the Week 5 game this weekend against the division-rival Jacksonville Jaguars. Things were trending this way after Taylor suffered what was described as a minor right high-ankle sprain in the Week 4 win over the Pittsburgh Steelers. The 25-year-old isn't going on Injured Reserve but he's out for this week and could be up in the air to face the division-rival Tennessee Titans in Week 6. It's a big blow for Indy's offense, which could also be without quarterback Anthony Richardson (abdomen, oblique) against Jacksonville. With Taylor out, Trey Sermon is expected to be the Colts' primary back in Week 5, giving him RB2/3 plug-and-play fantasy appeal off the waiver wire if you have Taylor or are desperate for some RB help this week. In addition to Sermon having a bigger role, Tyler Goodson will also see more work as the backup.--Keith Hernandez
Source: ESPN - Adam Schefter
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