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4 years agoThe Cardinals Defense struggled to contain Jalen Hurts and the Philadelphia Eagles in Week 15. However, they face a favorable matchup in Week 16, going up against an injury-riddled San Francisco 49ers team that will have C.J. Beathard under center. In addition to having their third-string quarterback starting this week, the 49ers will also be without their No. 1 running back Raheem Mostert (ankle), who has been shut down for the season. The Cardinals Defense has performed well against weak or injury-riddled offenses throughout the year. Most recently, they held the New York Giants to just seven points in Week 14. Start the Cardinals Defense in Week 16 and look for them to hold the 49ers to under 20 points and create a few turnovers as well.--Andrew Ericksen - RotoBaller
Source: ESPN

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