🖥 CYBER MONDAY - TAP TO SAVE 50% WITH CODE CYBER
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Monday Night Football Starts and Sits: Chargers at Saints

Fantasy football starts/sits and lineups advice for the Chargers vs. Saints MNF game in Week 5. Dan Fornek analyzes the matchups with a detailed breakdown.

Week 4 has come and gone and COVID remains prevalent in the NFL heading to Week 5. With bye weeks upon us, fantasy managers also have to contend with positive cases for the Titans, Patriots, Raiders, and Chiefs. All of us understood these possibilities heading into the season, but seeing the NFL move games is still an odd sight.

Looking to Week 5, the primary Monday Night Football matchup comes in the form of the Los Angeles Chargers and New Orleans Saints. The Chargers have declared rookie first-round pick Justin Herbert their starting quarterback after three strong performances to open his career. The Chargers come into this game somewhat banged up on offense thanks to an injury to Austin Ekeler in Week 4 and Mike Williams in Week 3.

Meanwhile, the Saints are hoping to get Michael Thomas and Jared Cook back for this game after both players missed Week 4. It could be irrelevant though given the fact that Alvin Kamara looks as explosive as ever and is dominating teams both on the ground and in the air. With Drew Brees rounding into form after a quarter of the season, this game could be more entertaining than it looked at the start of the year.

Be sure to check all of our fantasy football rankings for 2025:

 

Los Angeles Chargers at New Orleans Saints 

  • Game time: Monday 10/12 @ 8:15 EST
  • Game line: New Orleans -7
  • Over/Under: 50.5

 

Must-Starts

Drew Brees (QB, NO)

After a shaky opening to the season, Drew Brees seems to have righted the ship a bit in recent weeks. Despite not having access to Michael Thomas in the passing game, Brees has thrown for 534 yards and five touchdowns (with one interception) the past two weeks against the Packers and Lions. If Thomas can play (more on him a bit later), it will at the very least force coverage to account for him and open up his other weapons. The Chargers have struggled in the passing game on defense this season without Derwin James, allowing 22.7 points per week to opposing quarterbacks. They are fresh off Tom Brady throwing for five touchdowns without Chris Godwin and with a hobbled Mike Evans.

UPDATE: Michael Thomas has officially been ruled out for Week 5.

Justin Herbert (QB, LAC)

Justin Herbert continues to be the rookie surprise at the quarterback position. Herbert wasn’t able to surpass 300 passing yards for the third time in three starts, but he did complete a career-high 80% of his passes and three touchdowns against a relatively strong Tampa Bay defense in Week 4. The Chargers may be 0-3 in Herbert’s three starts, but he has played well enough to keep them within a touchdown against the Chiefs, Panthers, and Buccaneers, which isn’t too bad. Herbert will likely have to throw it again in Week 5 against the Saints, a secondary that has allowed 11 passing touchdowns this season and 22.2 points to quarterbacks per week.

Alvin Kamara (RB, NO)

Alvin Kamara failed to meet his lofty expectations in 2020 in what should have been a smash spot against the Lions. Kamara was still productive, carrying the ball 19 times for 83 yards and a touchdown while adding three receptions and 36 yards through the air, but he wasn’t needed once the Saints overcame a 14-point deficit to take a commanding lead against the Lions. It didn’t help that Latavius Murray was able to steal two scores from him in the red zone. Kamara has been the RB1 in fantasy this season, a trend that should continue against the Chargers. Los Angeles has done very well against the run this year (315 yards) but has struggled against pass-catching backs (154 yards and two scores), setting up for a great Kamara game once again.

Latavius Murray (RB, NO)

If you drafted Latavius Murray in your fantasy draft, then you have been happy with the results considering where you got him (typically right before or around the double-digit rounds). Murray has had at least 12 carries in three games, giving him a consistent enough workload to be a bye week fill-in or flex play. The only game where Murray failed to log a strong workload was a loss to the Raiders where the Saints were caught playing catch up the whole night. He has also been targeted at least once in every game, which adds to his value. Murray isn’t the strongest play, but in a week where numerous options are on bye or facing a COVID cancellation, you could do worse than a double-digit carry back.

Joshua Kelley (RB, LAC)

With Austin Ekeler out of the picture, Joshua Kelley would seem to be the logical player to see an increase in work. For one, he has already been utilized in a heavy usage role, totaling 35 carries for 124 yards and a touchdown the first two weeks of the season. Kelley has also seen an uptick in the passing game lately (despite going down to just 17 carries since Week 2), totaling seven catches (on seven targets) for 88 yards since Week 2. Kelley will likely split time with Justin Jackson, the RB2 in Los Angeles at the beginning of last season, but should have a solid game with double-digit touches. This week’s matchup isn’t great (New Orleans is only allowing 19 points per game to running backs), but Kelley should have the workload to justify a spot as your RB2.

Tre'Quan Smith (WR, NO)

After the Michael Thomas injury, Tre'Quan Smith has seen his role and production grow in the New Orleans Saints’ offense. Smith has been targeted 17 times since Week 1, catching 13 passes for 182 yards and two touchdowns. This culminated in a perfect week against the Lions where Smith caught all four of his targets for 54 yards and two scores. Michael Thomas may be able to return on Monday night, so time will tell on how concrete Smith’s role will be if that happens. However, Thomas will likely need time to shake off his high ankle sprain, making Smith a startable player given bye weeks and potential COVID cancellations.

UPDATE: Michael Thomas has officially been ruled out for Week 5.

Keenan Allen (WR, LAC)

The emergence of Justin Herbert as a legitimate passer has provided a stable weekly floor for Keenan Allen. Since Week 1, Allen has been targeted 40 times, catching 28 passes for 290 yards and a touchdown against some solid competition. He has always been a fringe WR1, and the Chargers’ young quarterback hasn’t done anything to end that trend. Marshon Lattimore will be Allen’s stiffest competition so far this season, but given his double-digit target floor, he must be in your lineup no matter what.

Hunter Henry (TE, LAC)

Hunter Henry finally had his first down week against a tough linebacking and safety corps in Tampa Bay. After seeing at least seven targets and catching five passes the first three weeks, Henry only caught two of four targets for 39 yards in Week 4. Henry has been steady and reliable this season, serving as the safety blanket for Justin Herbert. He should have no problem getting back on track against a Saints Defense that has allowed 16.3 points per week to tight ends (second-worst in the NFL). The New Orleans secondary is allowing 10.3 yards per reception and five touchdowns to tight ends through four games this season.

 

Consider Sitting

Emmanuel Sanders (WR, NO)

After an initial disappointment as the Saints’ WR1 in the wake of the Michael Thomas injury, Sanders has been utilized far better in the past two weeks. Sanders was targeted nine times against the Lions in Week 4, catching six passes for 93 yards in an impressive come from behind victory against Detroit. These past three weeks probably were important for Sanders and quarterback Drew Brees to establish some rapport given the condensed offseason program they both faced. Even with Thomas potentially returning, the Chargers have two of the best perimeter cornerbacks in the league with Casey Hayward and Desmond King. Sanders will be up for a challenge, but with all the COVID-related madness, he may be a worthy pivot if you have a player with a safer matchup.

Mike Williams (WR, LAC)

This one is pretty simple: Mike Williams hasn’t played since early in Week 3 thanks to a hamstring and is registered as a "did not play" against the Buccaneers. Despite the week of rest, Mike Williams missed practice through Thursday of Week 5 as well. Even if Williams can practice over the weekend, we have seen players struggle to recover from hamstring strains only to reinjure them when going full speed again. Give Williams a week to prove he is healthy before re-inserting him into your starting lineups.

Jared Cook (TE, NO)

Like Michael Thomas, Jared Cook has also been practicing on a limited basis this week. With an extra day to practice, he should have the ability to get close to ready after having Week 4 off against the Lions. Cook has had a relatively modest role for the Saints this year, catching nine of 15 targets for 114 yards and a touchdown in three games. Given the poor state of fantasy tight ends, that is a downright robust line that probably got him close to a TE1 through three weeks. Waiting until Monday to play Cook is a dangerous game, especially against a Chargers Defense that has allowed only 10.3 points to tight ends every week this year.

Potential Sleepers

Justin Jackson (RB, LAC)

Justin Jackson saw a spike in his role after the injury to Austin Ekeler in Week 4 (although to be fair, it isn’t hard to see a workload spike when your previous two weeks were zero percent of the offensive snaps). Jackson carried the ball six times for nine yards and added two catches for 12 yards in the loss to the Buccaneers. However, he was on the field for 40% of the time, which suggests he could see an uptick in his work on the field. Jackson played well last season during the Melvin Gordon holdout, and will likely see 40% of the backfield’s touches with Ekeler injured. If you need a desperation flex play, he should be serviceable.

Jalen Guyton (WR, LAC)

Jalen Guyton has been a serviceable player during Mike Williams’ absence thanks to a hamstring injury. Guyton has been targeted seven times, catching five passes for 125 yards and two touchdowns. He has filled in the role of a downfield threat well and should continue to do so with Williams on the mend. Guyton has a high-risk, high-reward feel to him this week with Keenan Allen likely to draw the attention of Marshon Lattimore and the injury to Austin Ekeler.

Adam Trautman (TE, NO)

To be clear, the only way Adam Trautman should find his way into your lineup is if Jared Cook doesn’t play AND you missed your waiver period the last week due to a catastrophic fantasy football blunder. Trautman registered no stats last week and played only 27% of the Saints' snaps in Week 4 despite the absence of Jared Cook. Trautman comes from the University of Dayton (like a certain someone writing this article) and still likely needs time to develop. He is an absolute desperation play but could find himself with a touchdown at any time given the injuries to the Saints.

 

Tough Call

Michael Thomas (WR, NO)

For the second straight week, Michael Thomas has been limited in practice trying to test out his ankle. Last week, it turned him into a late scratch against the Lions and only time will tell what the result of this week’s work will be. Ultimately, I would be wary of Thomas heading into this Monday night matchup. High ankle sprains notoriously take a lot of time to heal and we have seen numerous players recently (Alvin Kamara and Saquon in 2019) struggle once they return. A hobbled Thomas being hounded by Casey Hayward on defense is a potential recipe for disaster. It is very difficult to pivot off the player you likely took in the mid-to-late first round of your fantasy draft, but I am extremely skeptical of Thomas’ ability to produce in a tough matchup on Monday night.

UPDATE: Michael Thomas has officially been ruled out for Week 5.



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Start/Sit Advice




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Tyrone Tracy Jr.

Carted Off With Hip Injury on Monday Night
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
Davante Adams

Not Dealing With a Serious Injury
Brandon Miller

Unavailable on Monday
Kyler Murray

Surgery Not on the Table for Kyler Murray
Duncan Robinson

Absent Against Atlanta
Marvin Harrison Jr.

in Danger of Missing Week 14?
Jalen Duren

Back in the Lineup on Monday Evening
Noah Clowney

Cleared to Play Versus Charlotte
Giannis Antetokounmpo

Active On Monday
Danila Yurov

Won't Play on Tuesday
Michael Porter Jr.

Back in Action on Monday
Sam Merrill

Unavailable Versus Pacers
David Pastrnak

to Remain Out Tuesday
Alexandre Sarr

Won't Play Versus Milwaukee
Adam Gaudette

Iffy for Monday
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
Logan Cooley

a Game-Time Decision Monday
Josh Norris

Available Monday
Neal Pionk

Remains Out Monday
Lonzo Ball

Ruled Out on Monday
Jimmy Snuggerud

to Miss Six Weeks After Wrist Surgery
Justin Herbert

Having Hand Surgery on Monday
Steven Adams

Out Against Jazz
Kyler Murray

Cardinals Won't Open Kyler Murray's Practice Window This Week
Darius Garland

Unavailable Monday
Sauce Gardner

Not a Candidate to Go on Injured Reserve
Kristaps Porzingis

Out of Action Versus Pistons
Jayden Daniels

Not Cleared for Contact, Decision on Week 14 Status Delayed
Daniel Gafford

Sidelined Again on Monday
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job
Trey Hendrickson

Doubtful to Return in Week 14
Tee Higgins

Still in the Concussion Protocol
Drake London

"has a Chance" to Play in Week 14
J.J. McCarthy

in Line to Start in Week 14?
Aaron Jones Sr.

Not Dealing With Serious Shoulder Injury, Likely Day-to-Day
Sam Darnold

Dealing With Ankle Injury, "Should be Good" for Week 14
CFB

Will Stein, Brian Hartline the Top Candidates for Kentucky Job?
CFB

Nebraska Fires Defensive Coordinator John Butler After One Season
CFB

UCLA Expected to Hire Bob Chesney as Next Head Coach
Sauce Gardner

Officially Week-to-Week with Strained Calf
CFB

Lane Kiffin to Make $13 Million Salary, Ties Kirby Smart
CFB

Buster Faulkner, Joey Halzle Candidates for Florida Offensive Coordinator Job?
CFB

Kentucky Officially Fires Mark Stoops
Justin Herbert

Has Metacarpal Fracture in Left Hand
Amon-Ra St. Brown

Week 14 Availability Up in the Air
VEG

Carter Hart Expected to Make Golden Knights Debut Tuesday
Andre Drummond

Leaves Early, Status Now in Question
Pyotr Kochetkov

Remains Without Timeline For Return
Boone Jenner

Close to Returning
Tre Mann

Uncertain for Monday's Game Against Nets
Lian Bichsel

Exits With Injury Sunday
Deandre Ayton

Leaves Game With Knee Soreness
Petr Mrazek

Injured in Sunday's Loss
Adam Fox

Placed on Long-Term Injured Reserve
Brandon Williams

Questionable With Adductor Issue
P.J. Washington

Uncertain For Monday's Contest
Daniel Gafford

Expected To Miss Second Straight Game
Zach Ertz

Leads Washington in Receiving in Overtime Loss
James Cook

Handles Career-High 32 Carries for 144 Yards in Win
Egor Demin

Available Against Hornets
Justin Herbert

Planning to Play Through Broken Bone in Left Hand in Week 14
Terance Mann

in Danger of Missing Monday's Game
Sauce Gardner

Likely to Miss a "Couple of Weeks" With Calf Strain
CFB

Lane Kiffin to be Introduced as LSU's Next Head Coach on Monday
CFB

Florida Poised to Land Jon Sumrall as Next Head Coach
CFB

Alex Golesh Taking Over Auburn Head-Coaching Job
CFB

Arkansas Expected to Hire Ryan Silverfield as Next Head Coach
Joel Hofer

Shuts Out Mammoth
Owen Tippett

Amasses Three Points in Saturday's Win
Stuart Skinner

Bounces Back With Shutout
Brock Nelson

Notches Four Points in Big Win
Oliver Ekman-Larsson

Sustains Upper-Body Injury
Logan Cooley

Hurt in Saturday's Loss
Warren Foegele

Not Ready to Return Saturday
Simon Benoit

Won't Play Saturday
Zack Wheeler

Likely to Return in May
Ryan Helsley

Agrees to Two-Year Deal With Orioles
Dylan Cease

Agrees With Blue Jays on Seven-Year, $210 Million Deal
Anthony Rendon

Angels Could Buy Out Final Year of Anthony Rendon's Contract
Josh Hader

Says his Shoulder is "Back to Normal"
Ketel Marte

Diamondbacks "Actively Listening" on Ketel Marte

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP