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The injuries around the National Football League continue to pile up. With guys like Joe Mixon, Clyde Edwards-Helaire, and Cooper Kupp sidelined in Week 12; the door is open for others to shine. Let's check out our Week 12 fantasy football FLEX rankings as of November 27th. Our goal is to help you set those winning lineups, so let's see where key FLEX options like Samaje Perine, Joshua Palmer, Latavius Murray, Christian Watson, Donovan Peoples-Jones, and Treylon Burks rank, among others.
Our FLEX fantasy football rankings are put together by Nick Mariano, Brandon Murchison, and Andersen Pickard. In addition to our staff rankings, below you will also find a summary of the important fantasy football injury news for this week. There are always key injuries to keep track of, so be sure to check back until kickoff.
You should also bookmark our fantasy football rankings portal and check back regularly for updates. In addition to these FLEX rankings, read our fantasy football articles and analysis - our NFL team discusses lineup sleepers, busts, NFL players to start and sit, waiver wire pickups, and so much more. Most importantly, our brand new free mobile app is a must-have - download it and configure your notifications. We deliver all the top NFL news, injuries, and fantasy analysis 24x7 with our free push notification alerts!
Be sure to check all of our fantasy football rankings for the 2025 playoffs:- Quarterback fantasy football rankings
- Running back fantasy football rankings
- Wide receiver fantasy football rankings
- Tight end fantasy football rankings
- Kicker fantasy football rankings
- FLEX fantasy football rankings
- Defense (D/ST) fantasy football rankings
- Superflex fantasy football rankings
- IDP fantasy football rankings
- Dynasty fantasy football rankings
Week 12 FLEX Fantasy Football News and Injuries
- Marquise Brown Activated From Injured Reserve
- Ja'Marr Chase Officially Out On Sunday
- Joe Mixon Ruled Out For Week 12
- Gus Edwards Expected To Suit Up In Week 12
- Kyler Murray Ready To Return Against Chargers
- Leonard Fournette Officially Out
- JuJu Smith-Schuster Will Face The Rams
- Jerry Jeudy, KJ Hamler Ruled Out
- Lamar Jackson Not On Final Injury Report
- Romeo Doubs Ruled Out In Week 12
- Keenan Allen, Gerald Everett Good To Go
- Mike Williams Ruled Out Against Cardinals
- Samaje Perine Has Massive Upside In Week 12
- George Pickens A Flex Option In Week 12
- Joshua Palmer A WR2 For Week 12
- Latavius Murray Removed From Injury Report
- Tyler Boyd Looking To Rebound Against Tennessee
- Curtis Samuel A Low-End Flex Option In Week 12
- Christian Watson A Flex Option In Week 12
- Treylon Burks Looks To Build On Breakout Game
- Donovan Peoples-Jones A Solid Flex Vs. Bucs
- Drake London Faces Favorable Matchup
- Parris Campbell Remains High-Volume Option In Week 12
- Tyler Higbee Questionable For Week 12
- Greg Dulcich A Low-End TE1 Against Panthers
- Gus Edwards Trending Toward Playing Sunday
- Cam Akers A Possible Start In Deep Leagues
- Allen Robinson Expected To Miss Week 12
- Josh Jacobs On Track To Play Sunday
- Deebo Samuel Expected To Play In Week 12
- Greg Dortch Likely Out In Week 12
- Justin Fields A "Long Shot To Play" Against Jets
- Kyren Williams Garnering Flex Consideration In Week 12
- Ameer Abdullah Should Remain Involved In Passing Game
- Ke'Shawn Vaughn In Line For More Snaps Sunday
- Jerick McKinnon Trending Up In PPR Leagues
- Isaiah Likely Downgraded To Out
- Jaylen Warren Won't Play In Week 12
- Giovani Bernard Activated Off Injured Reserve
- Leonard Fournette Ruled Out For Week 12
- DeSean Jackson Active For Week 12
Week 12 Fantasy Football FLEX Rankings
You can also check out our Week 12 Half-PPR rankings and Standard rankings. A big congrats to our very own Nick Mariano who once again finished as a top-10 ranker in 2021 across the entire fantasy football industry!
Last updated on Sunday 11/27 at 8:00 am ET:
| FLEX Rank |
Player Name |
Pos. | Overall Rank |
| 1 | Tyreek Hill | WR | 1 |
| 2 | Stefon Diggs | WR | 2 |
| 3 | Austin Ekeler | RB | 3 |
| 4 | Jonathan Taylor | RB | 4 |
| 5 | Davante Adams | WR | 5 |
| 6 | Derrick Henry | RB | 6 |
| 7 | Christian McCaffrey | RB | 7 |
| 8 | Travis Kelce | TE | 8 |
| 9 | Kenneth Walker III | RB | 9 |
| 10 | Josh Jacobs | RB | 10 |
| 11 | Saquon Barkley | RB | 11 |
| 12 | CeeDee Lamb | WR | 12 |
| 13 | DeAndre Hopkins | WR | 13 |
| 14 | Justin Jefferson | WR | 14 |
| 15 | Tony Pollard | RB | 15 |
| 16 | Dalvin Cook | RB | 16 |
| 17 | Nick Chubb | RB | 17 |
| 18 | Jeff Wilson Jr. | RB | 18 |
| 19 | Travis Etienne Jr. | RB | 19 |
| 20 | Jaylen Waddle | WR | 20 |
| 21 | Aaron Jones | RB | 21 |
| 22 | Rachaad White | RB | 22 |
| 23 | Terry McLaurin | WR | 23 |
| 24 | Amon-Ra St. Brown | WR | 24 |
| 25 | A.J. Brown | WR | 25 |
| 26 | Mark Andrews | TE | 26 |
| 27 | Rhamondre Stevenson | RB | 27 |
| 28 | James Conner | RB | 28 |
| 29 | Tee Higgins | WR | 29 |
| 30 | DK Metcalf | WR | 30 |
| 31 | Amari Cooper | WR | 31 |
| 32 | Mike Evans | WR | 32 |
| 33 | Brandon Aiyuk | WR | 33 |
| 34 | Deebo Samuel | WR | 34 |
| 35 | Jamaal Williams | RB | 35 |
| 36 | Alvin Kamara | RB | 36 |
| 37 | Chris Godwin | WR | 37 |
| 38 | Tyler Lockett | WR | 38 |
| 39 | Chris Olave | WR | 39 |
| 40 | Devin Singletary | RB | 40 |
| 41 | Keenan Allen | WR | 41 |
| 42 | Samaje Perine | RB | 42 |
| 43 | Christian Kirk | WR | 43 |
| 44 | Gabe Davis | WR | 44 |
| 45 | Michael Pittman Jr. | WR | 45 |
| 46 | David Montgomery | RB | 46 |
| 47 | Antonio Gibson | RB | 47 |
| 48 | Miles Sanders | RB | 48 |
| 49 | Dameon Pierce | RB | 49 |
| 50 | Najee Harris | RB | 50 |
| 51 | Jakobi Meyers | WR | 51 |
| 52 | DeVonta Smith | WR | 52 |
| 53 | JuJu Smith-Schuster | WR | 53 |
| 54 | Tyler Boyd | WR | 54 |
| 55 | Joshua Palmer | WR | 55 |
| 56 | George Pickens | WR | 56 |
| 57 | Courtland Sutton | WR | 57 |
| 58 | George Kittle | TE | 58 |
| 59 | Isiah Pacheco | RB | 59 |
| 60 | Garrett Wilson | WR | 60 |
| 61 | Latavius Murray | RB | 61 |
| 62 | Darius Slayton | WR | 62 |
| 63 | D'Andre Swift | RB | 63 |
| 64 | D'Onta Foreman | RB | 64 |
| 65 | DJ Moore | WR | 65 |
| 66 | Curtis Samuel | WR | 66 |
| 67 | Dalton Schultz | TE | 67 |
| 68 | Pat Freiermuth | TE | 68 |
| 69 | Treylon Burks | WR | 69 |
| 70 | Christian Watson | WR | 70 |
| 71 | Allen Lazard | WR | 71 |
| 72 | T.J. Hockenson | TE | 72 |
| 73 | Diontae Johnson | WR | 73 |
| 74 | Donovan Peoples-Jones | WR | 74 |
| 75 | Parris Campbell | WR | 75 |
| 76 | Darnell Mooney | WR | 76 |
| 77 | Michael Carter | RB | 77 |
| 78 | Drake London | WR | 78 |
| 79 | Brian Robinson Jr. | RB | 79 |
| 80 | Brandin Cooks | WR | 80 |
| 81 | Zay Jones | WR | 81 |
| 82 | Adam Thielen | WR | 82 |
| 83 | Dawson Knox | TE | 83 |
| 84 | Cordarrelle Patterson | RB | 84 |
| 85 | Demarcus Robinson | WR | 85 |
| 86 | Ezekiel Elliott | RB | 86 |
| 87 | Nico Collins | WR | 87 |
| 88 | Michael Gallup | WR | 88 |
| 89 | Marquise Brown | WR | 89 |
| 90 | Jarvis Landry | WR | 90 |
| 91 | Marquez Valdes-Scantling | WR | 91 |
| 92 | DeAndre Carter | WR | 92 |
| 93 | Mack Hollins | WR | 93 |
| 94 | Damien Harris | RB | 94 |
| 95 | Elijah Mitchell | RB | 95 |
| 96 | Hayden Hurst | TE | 96 |
| 97 | Foster Moreau | TE | 97 |
| 98 | Tyler Higbee | TE | 98 |
| 99 | Greg Dulcich | TE | 99 |
| 100 | Robert Woods | WR | 100 |
| 101 | Alec Pierce | WR | 101 |
| 102 | Gus Edwards | RB | 102 |
| 103 | Kalif Raymond | WR | 103 |
| 104 | Evan Engram | TE | 104 |
| 105 | Kyren Williams | RB | 105 |
| 106 | Isaiah McKenzie | WR | 106 |
| 107 | Cole Kmet | TE | 107 |
| 108 | Devin Duvernay | WR | 108 |
| 109 | Gerald Everett | TE | 109 |
| 110 | David Njoku | TE | 110 |
| 111 | Jerick McKinnon | RB | 111 |
| 112 | Cam Akers | RB | 112 |
| 113 | Juwan Johnson | TE | 113 |
| 114 | Randall Cobb | WR | 114 |
| 115 | Tyler Conklin | TE | 115 |
| 116 | Tyler Allgeier | RB | 116 |
| 117 | Van Jefferson | WR | 117 |
| 118 | Julio Jones | WR | 118 |
| 119 | James Cook | RB | 119 |
| 120 | Terrace Marshall Jr. | WR | 120 |
| 121 | Kenyan Drake | RB | 121 |
| 122 | K.J. Osborn | WR | 122 |
| 123 | Jahan Dotson | WR | 123 |
| 124 | Corey Davis | WR | 124 |
| 125 | AJ Dillon | RB | 125 |
| 126 | Noah Brown | WR | 126 |
| 127 | Noah Fant | TE | 127 |
| 128 | James Robinson | RB | 128 |
| 129 | Ben Skowronek | WR | 129 |
| 130 | Kendall Hinton | WR | 130 |
| 131 | Nick Westbrook-Ikhine | WR | 131 |
| 132 | Kareem Hunt | RB | 132 |
| 133 | Marvin Jones Jr. | WR | 133 |
| 134 | Logan Thomas | TE | 134 |
| 135 | Elijah Moore | WR | 135 |
| 136 | Austin Hooper | TE | 136 |
| 137 | Chris Moore | WR | 137 |
| 138 | Trey McBride | TE | 138 |
| 139 | Olamide Zaccheaus | WR | 139 |
| 140 | Dontrell Hilliard | RB | 140 |
| 141 | Chase Claypool | WR | 141 |
| 142 | Damiere Byrd | WR | 142 |
| 143 | Robert Tonyan | TE | 143 |
| 144 | Skyy Moore | WR | 144 |
| 145 | Taysom Hill | TE | 145 |
| 146 | Mike Gesicki | TE | 146 |
| 147 | Justin Watson | WR | 147 |
| 148 | D.J. Chark Jr. | WR | 148 |
| 149 | Chuba Hubbard | RB | 149 |
| 150 | Hunter Henry | TE | 150 |
| 151 | Laviska Shenault Jr. | WR | 151 |
| 152 | Trent Sherfield | WR | 152 |
| 153 | Jauan Jennings | WR | 153 |
| 154 | Marquise Goodwin | WR | 154 |
| 155 | Quez Watkins | WR | 155 |
| 156 | DeVante Parker | WR | 156 |
| 157 | Kenneth Gainwell | RB | 157 |
| 158 | Richie James Jr. | WR | 158 |
| 159 | Tyquan Thornton | WR | 159 |
| 160 | Will Dissly | TE | 160 |
| 161 | Alexander Mattison | RB | 161 |
| 162 | Sammy Watkins | WR | 162 |
| 163 | Kenny Golladay | WR | 163 |
| 164 | Braxton Berrios | WR | 164 |
| 165 | David Bell | WR | 165 |
| 166 | Kylen Granson | TE | 166 |
| 167 | Harrison Bryant | TE | 167 |
| 168 | A.J. Green | WR | 168 |
| 169 | Cade Otton | TE | 169 |
| 170 | Giovani Bernard | RB | 170 |
| 171 | Jonnu Smith | TE | 171 |
| 172 | Josh Reynolds | WR | 172 |
| 173 | Rashid Shaheed | WR | 173 |
| 174 | Justice Hill | RB | 174 |
| 175 | Keaontay Ingram | RB | 175 |
| 176 | Equanimeous St. Brown | WR | 176 |
| 177 | Trenton Irwin | WR | 177 |
| 178 | Jordan Akins | TE | 178 |
| 179 | Steven Sims Jr. | WR | 179 |
| 180 | Phillip Dorsett II | WR | 180 |
| 181 | Caleb Huntley | RB | 181 |
| 182 | Marlon Mack | RB | 182 |
| 183 | Cameron Brate | TE | 183 |
| 184 | Brock Wright | TE | 184 |
| 185 | Keelan Cole Sr. | WR | 185 |
| 186 | Trestan Ebner | RB | 186 |
| 187 | Dante Pettis | WR | 187 |
| 188 | Deon Jackson | RB | 188 |
| 189 | Jack Stoll | TE | 189 |
| 190 | Matt Breida | RB | 190 |
| 191 | Zach Pascal | WR | 191 |
| 192 | Denzel Mims | WR | 192 |
| 193 | Nelson Agholor | WR | 193 |
| 194 | Justin Jackson | RB | 194 |
| 195 | Rex Burkhead | RB | 195 |
| 196 | Dyami Brown | WR | 196 |
| 197 | James Mitchell | TE | 197 |
| 198 | Noah Gray | TE | 198 |
| 199 | Boston Scott | RB | 199 |
| 200 | Isaiah Spiller | RB | 200 |
| 201 | Tre'Quan Smith | WR | 201 |
| 202 | Scotty Miller | WR | 202 |
| 203 | Ameer Abdullah | RB | 203 |
| 204 | Isaiah Hodgins | WR | 204 |
| 205 | Tommy Tremble | TE | 205 |
| 206 | Nyheim Hines | RB | 206 |
| 207 | Adam Trautman | TE | 207 |
| 208 | Chigoziem Okonkwo | TE | 208 |
| 209 | Travis Homer | RB | 209 |
| 210 | Trayveon Williams | RB | 210 |
| 211 | Tanner Hudson | TE | 211 |
| 212 | KhaDarel Hodge | WR | 212 |
| 213 | Mo Alie-Cox | TE | 213 |
| 214 | Shi Smith | WR | 214 |
| 215 | C.J. Uzomah | TE | 215 |
| 216 | Josh Oliver | TE | 216 |
| 217 | O.J. Howard | TE | 217 |
| 218 | Ty Johnson | RB | 218 |
| 219 | Lawrence Cager | WR | 219 |
| 220 | Khalil Shakir | WR | 220 |
| 221 | Kendrick Bourne | WR | 221 |
| 222 | Trent Taylor | WR | 222 |
| 223 | Teagan Quitoriano | TE | 223 |
| 224 | Raheem Blackshear | RB | 224 |
| 225 | Robbie Anderson | WR | 225 |
| 226 | Salvon Ahmed | RB | 226 |
| 227 | Colby Parkinson | TE | 227 |
| 228 | Brandon Johnson | WR | 228 |
| 229 | MyCole Pruitt | TE | 229 |
| 230 | Ashton Dulin | WR | 230 |
| 231 | Ke'Shawn Vaughn | RB | 231 |
| 232 | Marquez Callaway | WR | 232 |
| 233 | DeSean Jackson | WR | 233 |
| 234 | James Proche II | WR | 234 |
| 235 | Zach Gentry | TE | 235 |
| 236 | Chris Evans | RB | 236 |
| 237 | JaMycal Hasty | RB | 237 |
| 238 | Eric Saubert | TE | 238 |
| 239 | Jamal Agnew | WR | 239 |
| 240 | Ian Thomas | TE | 240 |
| 241 | Joshua Kelley | RB | 241 |
| 242 | Breshad Perriman | WR | 242 |
| 243 | Peyton Hendershot | TE | 243 |
| 244 | Kyle Juszczyk | RB | 244 |
| 245 | Byron Pringle | WR | 245 |
| 246 | Samori Toure | WR | 246 |
| 247 | Tutu Atwell | WR | 247 |
| 248 | John Bates | TE | 248 |
| 249 | Tom Kennedy | WR | 249 |
| 250 | Montrell Washington | WR | 250 |
| 251 | Jody Fortson | TE | 251 |
| 252 | Mark Ingram II | RB | 252 |
| 253 | Cedrick Wilson Jr. | WR | 253 |
| 254 | Zack Moss | RB | 254 |
| 255 | Velus Jones Jr. | WR | 255 |
| 256 | Shane Zylstra | TE | 256 |
| 257 | Gunner Olszewski | WR | 257 |
| 258 | Grant Calcaterra | TE | 258 |
| 259 | Sony Michel | RB | 259 |
| 260 | Brandon Bolden | RB | 260 |
| 261 | Malik Davis | RB | 261 |
| 262 | David Johnson | RB | 262 |
| 263 | Jake Ferguson | TE | 263 |
| 264 | Ronnie Rivers | RB | 264 |
| 265 | Brandon Powell | WR | 265 |
| 266 | Avery Williams | RB | 266 |
| 267 | Alec Ingold | RB | 267 |
| 268 | Eno Benjamin | RB | 268 |
| 269 | Ronald Jones II | RB | 269 |
| 270 | Benny Snell Jr. | RB | 270 |
| 271 | Parker Hesse | TE | 271 |
| 272 | Dwayne Washington | RB | 272 |
| 273 | Dan Arnold | TE | 273 |
| 274 | Geoff Swaim | TE | 274 |
| 275 | Jordan Wilkins | RB | 275 |
| 276 | Durham Smythe | TE | 276 |
| 277 | Mike Davis | RB | 277 |
| 278 | Chris Myarick | TE | 278 |
| 279 | Jordan Mason | RB | 279 |
| 280 | Hassan Haskins | RB | 280 |
| 281 | Jalen Virgil | WR | 281 |
| 282 | Josiah Deguara | TE | 282 |
| 283 | Gary Brightwell | RB | 283 |
| 284 | C.J. Ham | RB | 284 |
| 285 | Patrick Ricard | RB | 285 |
| 286 | Myles Gaskin | RB | 286 |
| 287 | Johnny Mundt | TE | 287 |
| 288 | Pierre Strong Jr. | RB | 290 |
| 289 | Reggie Gilliam | RB/TE | 293 |
| 290 | Dare Ogunbowale | RB | 297 |
| 291 | Stephen Anderson | TE | 298 |
| 292 | Tyrion Davis-Price | RB | 300 |
| 293 | DeeJay Dallas | RB | 301 |
| 294 | Michael Burton | RB | 303 |
| 295 | Zander Horvath | RB | 305 |
| 296 | Tre' McKitty | TE | 306 |
| 297 | Jelani Woods | TE | 308 |
| 298 | Devine Ozigbo | RB | 310 |
| 299 | Zamir White | RB | 311 |
| 300 | Anthony Firkser | TE | 313 |
| 301 | Cole Turner | TE | 316 |
| 302 | Tyree Jackson | TE | 319 |
| 303 | D'Ernest Johnson | RB | 320 |
| 304 | Maxx Williams | TE | 322 |
| 305 | Marcus Johnson | WR | 325 |
| 306 | Jakob Johnson | RB | 327 |
| 307 | Ray-Ray McCloud | WR | 329 |
| 308 | River Cracraft | WR | 332 |
| 309 | Michael Bandy | WR | 333 |
| 310 | Keith Smith | RB | 342 |
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