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Updated Week 6 fantasy football running back rankings as of October 15th, 2022. Set your winning lineups with our Week 6 NFL rankings for fantasy football.
It's already Week 6 in the NFL, and it feels like the season just began. The running back landscape is tumultuous, to say the least, as consensus #1 overall pick Jonathan Taylor has been ruled out and a handful of key backs have either been ruled out or come in as true question marks. See below for our updated Week 6 fantasy football running back rankings, as of October 15th. Our goal is to help you set those winning lineups, so let's see where key running backs like Raheem Mostert, Travis Etienne, Joe Mixon, Eno Benjamin, Najee Harris, and AJ Dillon rank, among others.
Our running back fantasy football rankings are put together by Nick Mariano, Brandon Murchison and Andersen Pickard. In addition to our staff rankings, below you will also find a summary of the important fantasy football injury news for this week. There are always key injuries to keep track of, so be sure to check back until kickoff.
You should also bookmark our fantasy football rankings portal and check back regularly for updates. In addition to these RB rankings, read our fantasy football articles and analysis - our NFL team discusses lineup sleepers, busts, NFL players to start and sit, waiver wire pickups and so much more. Most importantly, our brand new free mobile app is a must have - download it and configure your notifications. We deliver all the top NFL news, injuries, and fantasy analysis 24x7 with our free push notification alerts!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings (redraft)
- Dynasty fantasy football rankings
- 2025 NFL rookie fantasy football rankings
- Best ball fantasy football rankings
- Quarterback fantasy football rankings
- Running back fantasy football rankings
- Wide receiver fantasy football rankings
- Tight end fantasy football rankings
Week 6 Running Backs Fantasy Football News and Injuries
- Damien Harris A Game-Time Call For Week 6
- Jonathan Taylor, Nyheim Hines Ruled Out in Week 6
- Mike Boone Practices Fully On Friday
- Justice Hill Doubtful Against Giants
- Damien Harris Questionable For Week 6
- Raheem Mostert Officially Questionable Against Vikings
- Saquon Barkley Not On Final Injury Report
- James Conner Out For Week 6
- Cam Akers Out For Week 6
- Samaje Perine Logs A Full Practice On Friday
Week 6 Fantasy Football Running Back Rankings
You can also check out our Week 6 Half-PPR rankings and Standard rankings. A big congrats to our very own Nick Mariano who once again finished as a top-10 ranker in 2021 across the entire fantasy football industry!
Last updated on Sunday 10/16 at 9:30 am ET:
| RB Tier |
RB Rank |
Player Name |
Pos. | Overall Rank |
| 1 | 1 | Saquon Barkley | RB | 2 |
| 1 | 2 | Austin Ekeler | RB | 5 |
| 1 | 3 | Nick Chubb | RB | 6 |
| 1 | 4 | Christian McCaffrey | RB | 7 |
| 2 | 5 | Dalvin Cook | RB | 9 |
| 2 | 6 | Alvin Kamara | RB | 10 |
| 2 | 7 | Rhamondre Stevenson | RB | 14 |
| 2 | 8 | Aaron Jones | RB | 15 |
| 2 | 9 | Leonard Fournette | RB | 16 |
| 2 | 10 | Jeff Wilson Jr. | RB | 20 |
| 2 | 11 | Joe Mixon | RB | 21 |
| 2 | 12 | Breece Hall | RB | 24 |
| 2 | 13 | Eno Benjamin | RB | 27 |
| 2 | 14 | Miles Sanders | RB | 30 |
| 2 | 15 | Melvin Gordon III | RB | 33 |
| 3 | 16 | David Montgomery | RB | 36 |
| 3 | 17 | Ken Walker III | RB | 38 |
| 3 | 18 | Raheem Mostert | RB | 43 |
| 3 | 19 | J.K. Dobbins | RB | 46 |
| 3 | 20 | Clyde Edwards-Helaire | RB | 48 |
| 3 | 21 | Kareem Hunt | RB | 50 |
| 3 | 22 | Najee Harris | RB | 51 |
| 3 | 23 | James Robinson | RB | 52 |
| 3 | 24 | Darrell Henderson Jr. | RB | 56 |
| 3 | 25 | Devin Singletary | RB | 58 |
| 3 | 26 | Ezekiel Elliott | RB | 60 |
| 4 | 27 | Travis Etienne Jr. | RB | 61 |
| 4 | 28 | Deon Jackson | RB | 65 |
| 4 | 29 | AJ Dillon | RB | 67 |
| 4 | 30 | Tony Pollard | RB | 70 |
| 4 | 31 | Michael Carter | RB | 82 |
| 4 | 32 | Mike Boone | RB | 94 |
| 4 | 33 | Tyler Allgeier | RB | 96 |
| 4 | 34 | Brian Robinson Jr. | RB | 97 |
| 4 | 35 | J.D. McKissic | RB | 98 |
| 5 | 36 | Rachaad White | RB | 105 |
| 5 | 37 | Khalil Herbert | RB | 107 |
| 5 | 38 | Jerick McKinnon | RB | 108 |
| 5 | 39 | Alexander Mattison | RB | 111 |
| 5 | 40 | Phillip Lindsay | RB | 113 |
| 5 | 41 | Chase Edmonds | RB | 118 |
| 5 | 42 | Antonio Gibson | RB | 126 |
| 6 | 43 | Joshua Kelley | RB | 132 |
| 6 | 44 | Jaylen Warren | RB | 134 |
| 6 | 45 | DeeJay Dallas | RB | 136 |
| 6 | 46 | Samaje Perine | RB | 138 |
| 6 | 47 | Mark Ingram II | RB | 142 |
| 6 | 48 | Caleb Huntley | RB | 143 |
| 6 | 49 | Kenneth Gainwell | RB | 146 |
| 7 | 50 | James Cook | RB | 152 |
| 7 | 51 | Isiah Pacheco | RB | 156 |
| 7 | 52 | Tevin Coleman | RB | 160 |
| 7 | 53 | Avery Williams | RB | 161 |
| 7 | 54 | Zack Moss | RB | 171 |
| 7 | 55 | Myles Gaskin | RB | 173 |
| 7 | 56 | Mike Davis | RB | 180 |
| 7 | 57 | Matt Breida | RB | 181 |
| 8 | 58 | Kyle Juszczyk | RB | 182 |
| 8 | 59 | Latavius Murray | RB | 184 |
| 8 | 60 | D'Onta Foreman | RB | 191 |
| 8 | 61 | Sony Michel | RB | 192 |
| 8 | 62 | Chuba Hubbard | RB | 205 |
| 8 | 63 | Boston Scott | RB | 206 |
| 8 | 64 | Kenyan Drake | RB | 208 |
| 9 | 65 | Gary Brightwell | RB | 210 |
| 9 | 66 | Zander Horvath | RB | 219 |
| 9 | 67 | Mike Strachan | RB | 220 |
| 9 | 68 | Pierre Strong Jr. | RB | 227 |
| 9 | 69 | C.J. Ham | RB | 234 |
| 9 | 70 | Jordan Mason | RB | 236 |
| 10 | 71 | Jonathan Williams | RB | 237 |
| 10 | 72 | Chris Evans | RB | 238 |
| 10 | 73 | Patrick Ricard | RB | 239 |
| 10 | 74 | Ke'Shawn Vaughn | RB | 243 |
| 10 | 75 | Marlon Mack | RB | 245 |
| 10 | 76 | Darrel Williams | RB | 246 |
| 10 | 77 | Trestan Ebner | RB | 248 |
| 10 | 78 | Alec Ingold | RB | 251 |
| 10 | 79 | Dwayne Washington | RB | 252 |
| 10 | 80 | Malcolm Brown | RB | 255 |
| 10 | 81 | Ty Johnson | RB | 257 |
| 11 | 82 | Trey Sermon | RB | 260 |
| 11 | 83 | D'Ernest Johnson | RB | 261 |
| 11 | 84 | JaMycal Hasty | RB | 262 |
| 11 | 85 | Justice Hill | RB | 263 |
| 11 | 86 | Kene Nwangwu | RB | 264 |
| 11 | 87 | Benny Snell Jr. | RB | 266 |
| 11 | 88 | Rico Dowdle | RB | 268 |
| 11 | 89 | Reggie Gilliam | RB | 269 |
| 11 | 90 | Keaontay Ingram | RB | 270 |
| 12 | 91 | Khari Blasingame | RB | 272 |
| 12 | 92 | Devine Ozigbo | RB | 274 |
| 12 | 93 | Darrynton Evans | RB | 277 |
| 12 | 94 | Michael Burton | RB | 280 |
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