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Welcome to Week 6 RotoBallers. Below are our updated consensus Week 6 Flex rankings for fantasy football, including some running notes on relevant injuries, player news and rankings updates. These Flex rankings are geared towards making decisions for your Flex spot (RB/WR or RB/WR/TE), which in most leagues consists of running backs, wide receivers and in many cases tight ends as well:
- Dalvin Cook Taken Off Final Injury Report
- Terry McLaurin Tweaks Hamstring, Questionable For Week 6
- Mike Williams Is Questionable To Play
- Christian McCaffrey Officially Ruled Out, Placed On IR
- Nick Chubb Ruled Out For Week 6
- Kareem Hunt Officially Listed As Questionable
- Damien Williams Tested Positive For COVID-19
- Khalil Herbert In Line For Lead Role
- Tyreek Hill Is Questionable For Week 6
- Joe Mixon In Line For Full Workload
- Samaje Perine On The COVID-19 List
- Chris Carson Ruled Out, Lands On IR
- Antonio Gibson Officially Questionable In Week 6
- Justin Jefferson, Adam Thielen Good To Go
- Jarvis Landry Activated From IR, Questionable To Play
- Zach Ertz Traded To Cardinals
- Josh Jacobs Misses Thursday's Practice With An Illness
- DeVante Parker Ruled Out
- Sterling Shepard, Darius Slayton On Track To Return
These rankings are a consensus from four of our lead fantasy football columnists - Nick Mariano, Pierre Camus, Brandon Murchison and Scott Engel - who have all analyzed the NFL matchups and game slates for Week 6.
And in case you weren't aware, our very own Nick Mariano was ranked #11 overall in 2018 out of ~120 industry experts, and was ranked #9 overall the year before. So be sure to follow his rankings every week!
Be sure to check all of our fantasy football rankings for the 2025 playoffs:- Quarterback fantasy football rankings
- Running back fantasy football rankings
- Wide receiver fantasy football rankings
- Tight end fantasy football rankings
- Kicker fantasy football rankings
- FLEX fantasy football rankings
- Defense (D/ST) fantasy football rankings
- Superflex fantasy football rankings
- IDP fantasy football rankings
- Dynasty fantasy football rankings
Week 6 Fantasy Football Flex Rankings
You can also see our full Week 6 ranks for PPR, Half-PPR and Standard scoring.
Last updated on Sunday 10/17 at 11:00 am ET:
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More Weekly Lineup Prep
Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.
