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Welcome to Week 6 RotoBallers. Below are our updated consensus Week 6 Flex rankings for fantasy football, including some running notes on relevant injuries, player news and rankings updates. These Flex rankings are geared towards making decisions for your Flex spot (RB/WR or RB/WR/TE), which in most leagues consists of running backs, wide receivers and in many cases tight ends as well:
- Dalvin Cook Taken Off Final Injury Report
- Terry McLaurin Tweaks Hamstring, Questionable For Week 6
- Mike Williams Is Questionable To Play
- Christian McCaffrey Officially Ruled Out, Placed On IR
- Nick Chubb Ruled Out For Week 6
- Kareem Hunt Officially Listed As Questionable
- Damien Williams Tested Positive For COVID-19
- Khalil Herbert In Line For Lead Role
- Tyreek Hill Is Questionable For Week 6
- Joe Mixon In Line For Full Workload
- Samaje Perine On The COVID-19 List
- Chris Carson Ruled Out, Lands On IR
- Antonio Gibson Officially Questionable In Week 6
- Justin Jefferson, Adam Thielen Good To Go
- Jarvis Landry Activated From IR, Questionable To Play
- Zach Ertz Traded To Cardinals
- Josh Jacobs Misses Thursday's Practice With An Illness
- DeVante Parker Ruled Out
- Sterling Shepard, Darius Slayton On Track To Return
These rankings are a consensus from four of our lead fantasy football columnists - Nick Mariano, Pierre Camus, Brandon Murchison and Scott Engel - who have all analyzed the NFL matchups and game slates for Week 6.
And in case you weren't aware, our very own Nick Mariano was ranked #11 overall in 2018 out of ~120 industry experts, and was ranked #9 overall the year before. So be sure to follow his rankings every week!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings (redraft)
- Dynasty fantasy football rankings
- 2025 NFL rookie fantasy football rankings
- Best ball fantasy football rankings
- Quarterback fantasy football rankings
- Running back fantasy football rankings
- Wide receiver fantasy football rankings
- Tight end fantasy football rankings
Week 6 Fantasy Football Flex Rankings
You can also see our full Week 6 ranks for PPR, Half-PPR and Standard scoring.
Last updated on Sunday 10/17 at 11:00 am ET:
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Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.
