Updated Week 16 Flex Rankings (Top 200)

Welcome to Week 16 RotoBallers. Below are our updated consensus Week 16 Flex rankings for fantasy football, including some running notes on relevant injuries, player news and rankings updates. These Flex rankings are geared towards making decisions for your Flex spot (RB/WR or RB/WR/TE), which in most leagues consists of running backs, wide receivers and in many cases tight ends as well:

• Jarvis Landry, Rashard Higgins, Donovan Peoples-Jones (COVID) To Miss Week 16
• James Robinson Will Not Play
• DeVante Parker Officially Out For Saturday
• Mike Gesicki Is Active For Week 16
• James Conner Returns To Full Practice
• Ronald Jones II Officially Ruled Out
• Ezekiel Elliott Thinks He'll Play Against Eagles
• Julio Jones Officially Ruled Out
• Antonio Gibson Practicing Again, Expected To Play
• Terry McLaurin Listed As Doubtful, Not Expected To Play
• George Kittle May Will His Return On Saturday
• Myles Gaskin Activated From COVID-19 List
• Ito Smith Named #1 RB Over Todd Gurley II
• Keenan Allen Game-Time Decision, Not Expected To Play
• Tyler Boyd In Concussion Protocol
• Hunter Henry Placed On COVID-19 List, Ruled Out
• Larry Fitzgerald Listed As Questionable
• Tre'Quan Smith Lands On Injured Reserve
• Eric Ebron Practiced In Full
• Kyle Rudolph Has Been Officially Ruled Out
• Kenny Golladay Officially Out For Week 16
• Joe Mixon Won't Play In Week 16
• Christian McCaffrey Doubtful For Week 16
• John Brown Remains On Injured Reserve
• Clyde Edwards-Helaire Out For Remainder Of Regular Season
• Raheem Mostert's Season Likely Over
• Cam Akers To Miss Week 16
• Buffalo Not Overly Worried About Stefon Diggs’ Foot Ailment
• Greg Olsen On Track To Return To Action In Week 16

These rankings are a consensus from four of our lead fantasy football columnists - Nick Mariano, Pierre Camus, Brandon Murchison, Scott Engel, and Dominick Petrillo - who have all analyzed the NFL matchups and game slates for Week 16.

And in case you weren't aware, our very own Nick Mariano was ranked #11 overall in 2018 out of ~120 industry experts, and was ranked #9 overall the year before. So be sure to follow his rankings every week!

• 2025 fantasy football rankings (redraft)
• Dynasty fantasy football rankings
• 2025 NFL rookie fantasy football rankings
• Best ball fantasy football rankings
• Quarterback fantasy football rankings
• Running back fantasy football rankings
• Wide receiver fantasy football rankings
• Tight end fantasy football rankings

Week 16 Fantasy Football Flex Rankings

You can also see our full Week 16 ranks for PPR, Half-PPR and Standard scoring.

Last updated on Sunday 12/27 at 9:30 am ET:

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