PrizePicks NFL DFS Prop Picks - Over/Under Props for Week 16 (Sunday Main Slate)

Hello everybody, and welcome to our PrizePicks NFL DFS prop picks for Week 16 - Sunday Main Slate! The 2024 NFL season is now into the holiday season, and our friends over at PrizePicks have a TON of great DFS plays we can look to take advantage of.

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PrizePicks Over/Under DFS Props Contests

PrizePicks is a great DFS picks site where you can choose to select plays in terms of fantasy points or single stats. The goal is to build a 2-player, 3-player, 4-player, 5-player, or 6-player entry and then select whether or not you want to play for the power play or the flex play.

On the power play, you will need to be correct on each of your selections to win, and on the flex play, you will have a little more wiggle room for a chance to win some money back.

You can mix and match players from different games in your entry or select all of your plays from the same game. Once you have selected your players and props, you can choose the aforementioned flex play or power play option. Let's see what the board offers today!

NFL DFS Props - Over/Under Picks for Week 16

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Jahmyr Gibbs MORE than 88.5 rushing yards

This is a number we would not normally see on Gibbs, but he will be the focal point of the Lions' rushing attack with David Montgomery no longer in the mix after suffering a knee injury last week against the Buffalo Bills.

Gibbs has been a stellar back thus far for the Lions as he has rushed for 1,047 yards on just 186 carries, good for an average of over 5.6 yards per carry. The matchup this week is superb as well as he will be up against a struggling Bears defense.

Over the previous four weeks, the Bears have allowed the third-most rushing yards per game to running backs while allowing an average of over 4.8 yards per carry. The Lions are also 6.5-point favorites in this game and should be able to continue keeping the ball on the ground.

James Conner MORE than 22.5 receiving yards

James Conner has been an important factor in the passing game for the Arizona Cardinals in 2024. Conner has hauled in 41 receptions for 361 receiving yards overall. This matchup against the Carolina Panthers on the road should be a good spot for Conner to thrive.

Conner has eclipsed this total in four of his previous five games. The Panthers have also allowed eight running backs to go over this total on the season. The spread in this game is 4.5 points, which could be close enough to keep Arizona moving the ball through the air.

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