PrizePicks NFL DFS Prop Picks - 49ers vs. Seahawks Thursday Night Football

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NFL DFS Picks for 49ers at Seahawks

Christian McCaffrey more than 75.5 rushing yards - This is a rather high number for CMC as he has only eclipsed this total once in his previous five contests, but the matchup is ripe for a solid game here. The Seahawks have allowed the second-most rushing yards to running backs over the previous four weeks by allowing 522 yards. The Niners are also favored by 3.5 points, which lends to the running game. Add in the fact that the Niners could be on their fourth quarterback this season in Josh Johnson, and you have a recipe for success here.

Geno Smith more than 242.5 passing yards - While this may seem like a stretch for Smith, he has gone over this total in his five previous games. The Seahawks could also be without Kenneth Walker III or a limited version of him, which would also lead to more passing by this offense. The Niners have also been somewhat suspect against the pass in recent weeks as they have allowed nearly 260 passing yards per game over the previous four weeks. Seattle is also expected to be trailing in this game, so some extra passing can be expected.

Tyler Lockett more than 60.5 receiving yards- You could honestly take D.K. Metcalf or Tyler Lockett in this spot, but we are going to go with Lockett as he has amassed 21 targets over his previous two games and has been the hot hand for Seattle recently. He has also eclipsed this total in three of his previous five contests while missing it by just one yard in another. The Niners have struggled quite a bit against some pedestrian receivers over the previous four weeks as well by allowing nearly 200 receiving yards per game to the position.

Other Recommendations: D.K. Metcalf more than 62.5 receiving yards

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