Murray has a favorable matchup against the 49ers, a team that has struggled against opposing quarterbacks this season (ninth-most FPPG allowed to QB's, 18th in pass DVOA). He may be the best signal-caller that the San Francisco defense has seen all year, and our friends in Vegas have him throwing around 275 yards and nearly two touchdowns. That's not even including what he could do on the ground, where he's averaging about 27 rushing yards per game with three rushing touchdowns on the season.
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