RADIO
If you have players set to play on Monday night, you can read our Monday Night Football matchups analysis article for the Chargers vs. Cardinals game to help make any fantasy football lineup decisions for both season-long and DFS.
The Chargers are sitting at 3-2, while the Cardinals are seemingly in a must-win situation with a 2-4 record. Both teams have looked promising at times early in the 2024 campaign, and both organizations have a path to playoff contention. All in all, this should be an exciting AFC vs. NFC bout.
Let's waste no more time and dive into the fantasy football matchups for Kyler Murray, Justin Herbert, J.K. Dobbins, James Conner, Marvin Harrison Jr., Ladd McConkey, Michael Wilson, and more. Read our fantasy football breakdowns for this game -- the recommended starts, sits, and matchups we love heading into the Week 7 matchups. Good luck, RotoBallers!
Be sure to check all of our fantasy football rankings for the 2025 playoffs:- Quarterback fantasy football rankings
- Running back fantasy football rankings
- Wide receiver fantasy football rankings
- Tight end fantasy football rankings
- Kicker fantasy football rankings
- FLEX fantasy football rankings
- Defense (D/ST) fantasy football rankings
- Superflex fantasy football rankings
- IDP fantasy football rankings
- Dynasty fantasy football rankings
Los Angeles Chargers at Arizona Cardinals
Spread: Chargers -2.5
Implied Total: Chargers (23) vs. Cardinals (20.5)
Matchups We Love
Now, Justin Herbert being on the love list doesn't mean you should be automatically starting him this week. He has yet to finish as a top-20 fantasy quarterback this year, and he's averaging only 16 completions per game. However, he could be a potential QB2 option against the Cardinals in Week 7. Arizona has allowed the fourth-most fantasy points per game to quarterbacks this season.
Chargers WRs
It has been hard to rely on both Quentin Johnston and Ladd McConkey in fantasy this year. But both Chargers wideouts are potential flex plays in 12-plus team leagues in Week 7. The Cardinals have allowed the eighth-most fantasy points per game to wideouts this year and the fourth-most fantasy points per game to slot wideouts. So McConkey is a better play of the two Chargers playmakers.
Keep that football!
Ladd McConkey finds the blue paint for his first NFL TD!
📺: #LVvsLAC on CBS/Paramount+
📱: https://t.co/waVpO909ge pic.twitter.com/2Px6BcGS2W— NFL (@NFL) September 8, 2024
Update: Johnston (ankle) is doubtful for Monday, while McConkey is questionable. If McConkey plays, he should be the clear No. 1 option in the passing game.
Matchups We Hate
RB James Conner
James Conner only scored 6.6 PPR fantasy points last week, and things don't get easier for him in Week 7 against the Chargers. Los Angeles has given up the sixth-fewest fantasy points per game to opposing running backs this season. It has also yet to allow a top-16 fantasy running back through the first six weeks. As a result, Conner is a riskier RB2 option this weekend.
Other Matchups
QB Kyler Murray
It has been an up-and-down fantasy season so far for Kyler Murray. Murray has finished as a top-5 fantasy quarterback twice through six weeks while also finishing outside the top 16 three times. So it might be hard to trust him as your QB1 this week. But after seeing what Bo Nix did last week against the Chargers -- rushing for 61 yards and finishing with 21.7 fantasy points -- Murray will be a low-end QB1 in Week 7.
Bye bye Ky 👋 @AZCardinals take an early lead!
📺: #AZvsSF on FOX
📱: https://t.co/waVpO909ge pic.twitter.com/EUHKDDLEoO— NFL (@NFL) October 6, 2024
RB J.K. Dobbins
J.K. Dobbins saw a career-high 25 carries in last week's win over the Denver Broncos. While Dobbins won't see that many carries every week, he is a strong RB2 option this week against the Cardinals. He has finished as a top-15 running back in three of five games, and the Cardinals have allowed four running backs to finish top-15 at the position over the past four weeks.
There's a chance that Marvin Harrison Jr. (concussion) will suit up on Monday after practicing on Thursday. However, he'll be a low-end WR2 in Week 7 against the Chargers. Harrison has totaled over 65 receiving yards just once this season and now faces a Chargers secondary that has yet to allow a top-15 fantasy finish at the wide receiver position.
MARVIN HARRISON JR.'S FIRST NFL TOUCHDOWN HAS ARRIVED pic.twitter.com/EFquDWaM8V
— Arizona Cardinals (@AZCardinals) September 15, 2024
Update: Harrison practiced in full on Saturday, and he will play on Monday.
On paper, this might not seem like the best matchup for Michael Wilson, as the Chargers have given up the fifth-fewest fantasy points per game to opposing wideouts. But Los Angeles' secondary is currently banged up, and Ja'Sir Taylor (fibula) and Kristian Fulton (hamstring) could miss Monday's game. That makes Wilson a potential flex play in 12-plus team leagues. If Harrison is out, Wilson would be an even better play.
TE Trey McBride
McBride is Murray's favorite target in the passing game. He has caught at least six passes in three of the past four games while finishing in double figures in PPR formats in all three of those contests. The Cardinals tight end now faces a Chargers secondary that has allowed a top-3 fantasy tight end twice this season. So get him into your lineups this week.
Notable Injuries
- Quentin Johnston (ankle)
- Ladd McConkey (toe)
- DJ Chark (groin)
- Hayden Hurst (groin)
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