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Fantasy Football Injury Reports For NFL RBs: Week 6 Updates for Alvin Kamara, Bijan Robinson, Jonathan Taylor, James Cook

James Cook - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Below is our fantasy football injuries report for running backs in Week 6, as of October 12. The injury statuses for various NFL running backs are up in the air for Week 6, including Alvin Kamara, Bijan Robinson, Jonathan Taylor, and James Cook.

As the fantasy football season continues, every decision, transaction, and lineup change matters. These are critical running back injuries to keep track of throughout the week. Being up-to-date on NFL injury news can give you an edge over your league mates in fantasy football.

To keep close tabs on all the news across the NFL, favorite or bookmark the fantasy football player news page, or download the free RotoBaller fantasy football mobile app with push notification alerts on all the latest news. Let's look at the updates for some running backs and see whether they may play in Week 6.

Be sure to check all of our fantasy football rankings for the 2025 playoffs:

 

Alvin Kamara Injury Update

Kamara (hip, hand) has been cleared to play in Week 6 despite failing to log a full practice this week. Fantasy managers should deploy him as a mid-to-high RB1 against a Buccaneers defense that ranks among the league's worst when defending pass-catching backs.

 

Bijan Robinson Injury Update

Robinson (hamstring) was added to the injury report as a limited participant on Thursday, but he upgraded to a full participant on Friday and has been cleared to play in Week 6. He continues to rank as a low-end RB1 in most fantasy leagues.

 

Jonathan Taylor Injury Update

Taylor (ankle) has been ruled out after missing all three practices this week. He's now slated to miss his second consecutive game, leaving Trey Sermon in line to start for the Colts once again.

 

James Cook Injury Update

Cook (toe) was listed as a non-participant again after Friday's practice walkthrough. He presumably needs to get back on the field in some capacity on Saturday to play on Monday night against the Jets.

 

Brian Robinson Jr. Injury Update

Robinson (knee) missed all three practices this week. The Commanders have listed him as questionable and view him as a game-time decision, but it's difficult for any player to suit up on Sunday after failing to practice. If he can't start against the Ravens, Austin Ekeler and Jeremy McNichols would handle larger roles.

 

Austin Ekeler Injury Update

Ekeler (heel) was limited on Wednesday but has logged two full practices since then. The veteran has been removed from the injury report and will play this week versus Baltimore. He's a solid RB3/FLEX play who would jump to the RB2 tier if Robinson is ruled out.

 

Rachaad White Injury Update

White (foot) is doubtful for Week 6 after missing two consecutive practices. At this point, it would take some sort of miracle for him to play. Look for Bucky Irving to step up as Tampa Bay's primary running back on Sunday in New Orleans.

 

Joe Mixon Injury Update

Mixon (ankle) has logged back-to-back full practices and is officially questionable for Week 6 against the Patriots. Houston's backfield is a mess to decipher right now with Cam Akers starting the last two weeks, Pierce returning to the fold, and Joe Mixon (ankle) listed as questionable. If Mixon manages to play, he would lead the running back room, ranking as a low-end RB1 in fantasy football.

 

Rhamondre Stevenson Injury Update

Stevenson (foot) missed all three practices this week and has been ruled out for Sunday's game against the Texans. It has been an eventful couple of weeks for Stevenson and Antonio Gibson. Stevenson was benched for Gibson ahead of Week 5 but ended up leading the backfield in touches and logging their lone touchdown. Now, he's sidelined with Gibson and Ja'Mycal Hasty headed for expanded opportunities.

 

Travis Etienne Jr. Injury Update

Etienne (shoulder) was limited in practice this week but has been cleared to play against the Bears on Sunday morning in London. He has been quite underwhelming as of late but still has the upside to be a low-end RB1 in fantasy football. For now, managers should still deploy him in lineups.

 

Zamir White Injury Update

White (groin) upgraded to a limited participant on Friday after missing back-to-back practices. The Raiders have listed him as questionable, and while his outlook isn't particularly promising, the good news is that he managed to get on the field in some capacity to close out the week of practice. Regardless of his status on Sunday, White is tough to trust from a fantasy perspective.

 

Nick Chubb Injury Update

Chubb (knee) has been ruled out for Week 6 against the Eagles. The talented running back was limited in practice all week long, but it looks like the Browns will wait until he's a full participant before activating him. Jerome Ford will lead Cleveland's backfield on Sunday.

 

Devin Singletary Injury Update

Singletary (groin) was limited in practice all week long and is listed as questionable ahead of Sunday's game against the Bengals. If active, the veteran running back would rank as a fantasy RB3 while bumping Tyrone Tracy Jr. out of managers' starting lineups.

 

Trey Sermon Injury Update

Sermon (collarbone) has logged back-to-back full practices ever since being sidelined on Wednesday. He has been removed from the injury report and will play in Week 6. Sermon will lead Indianapolis' backfield once again with Jonathan Taylor (ankle) already ruled out versus Tennessee.

 

Zack Moss Injury Update

Moss (foot) has progressed every day this week, gradually going from a non-participant Wednesday to a full participant Friday. He has been removed from the injury report and will play against the Giants this week. He could be headed for a larger role if Chase Brown (quadricep) doesn't suit up.

 

Chase Brown Injury Update

Brown (quadricep) is questionable for Week 6 after logging two consecutive limited practices. It's promising that Brown practiced in some capacity every day this week, but he could still end up being a game-time decision. If the young running back is inactive, Zack Moss would handle extra opportunities.

 

Jaylen Warren Injury Update

Warren (knee) was a full participant on Friday, but the Steelers are still being careful by listing him as questionable for Week 6. Even if active, he'd be off the fantasy radar as an RB4 in most leagues.

 

Cordarrelle Patterson Injury Update

Patterson (ankle) has been ruled out after missing three consecutive practices. The veteran running back will give way to a backfield of Najee Harris, Aaron Shampklin, and possibly Warren (knee) this week.

 

Gus Edwards Injury Update

Edwards (ankle) has been ruled out after failing to practice this week. His absence will lead to extra opportunities for Hassan Haskins, who is now slated to back up J.K. Dobbins against Denver on Sunday.

 

Dameon Pierce Injury Update

Pierce (hamstring) has logged back-to-back full practices and will be active for Week 6 against the Patriots. Houston's backfield is a mess to decipher right now with Cam Akers starting the last two weeks, Pierce returning to the fold, and Joe Mixon (ankle) listed as questionable.

 

D'Onta Foreman Injury Update

Foreman (ankle) has gradually progressed this week, going from a non-participant Wednesday to a full participant Friday. He has been removed from the injury report and will play against the Eagles, presumably operating as the backup to Jerome Ford. The veteran has seen some solid volume lately, but he's still off the radar in most fantasy leagues.

 

Kendre Miller Injury Update

Miller (hamstring) practiced in full all week long, but the Saints are still listing him as questionable as they mull whether to activate him from injured reserve prior to the Saturday 4 p.m. deadline. Even if he is active for Week 6, Miller would not make his way onto the fantasy radar.

 

Nyheim Hines Injury Update

Hines (knee) has been ruled out for Week 6 against the Eagles. The talented special teamer was limited in practice all week long, but it looks like the Browns will wait until he's a full participant before activating him. Even once he returns, Hines will be a non-factor in most fantasy leagues.

 

Pierre Strong Jr. Injury Update

Strong (hamstring) logged a full practice on Friday after logging back-to-back limited practices. He has been removed from the injury report and will play on Sunday. He'll presumably operate as the Browns' No. 3 running back behind Ford and Foreman, keeping him off the fantasy radar for the time being.

 

Audric Estime Injury Update

Estime (ankle) is still listed as questionable despite being a full participant in practice this week. This designation is presumably a product of Estime being on injured reserve; Denver has until 4 p.m. Saturday to decide whether he should be activated and will likely take that decision up until the final minutes.

 

Rasheen Ali Injury Update

Ali (neck) is questionable to play on Sunday despite being a full participant in practice this week. The young running back remains on injured reserve and would need to be activated by 4 p.m. Saturday in order to suit up for this week's clash with Washington.

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