FanDuel NFL DFS Week 15 Picks: Top Daily Fantasy Lineup Plays Include Dak Prescott, Patrick Mahomes, Deebo Samuel, Travis Kelce, More

It’s a wonderful time of year, with the NFL expanding the schedule to include three games on Saturday. While an additional day of football is never bad, it can be semi-problematic for DFS enthusiasts, primarily since fewer players will be available. But depending on how you look at things, injuries across the league can be good, considering it opens the door for value opportunities. At the same time, more than a few teams aren’t expected to make the postseason (and they know it), potentially allowing lesser-known players to get in on the action.

Speaking of injuries, the Chargers will be without Justin Herbert for the remainder of the season after he suffered a fractured finger in last Sunday's loss to the Denver Broncos. In addition, Keenan Allen didn't play on Thursday because of a heel injury, although it is certainly possible fantasy managers have seen the last of him this season. Brandon Staley's days as the Chargers' head coach may also be nearing an end if they haven't already by the time this piece is read. 

In this article, I will be providing you with my Week 15 daily fantasy football lineup picks for FanDuel. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big!

FanDuel Quarterbacks - Week 15 DFS Lineup Picks

Dak Prescott - @ BUF ($8,600)

The Eagles were projected to run away with the NFC East entering the 2023-24 campaign. Unfortunately for Philadelphia, that isn't the case, as the team needs to turn things around in the final four weeks of the regular season. Of course, it's easy to say Philadelphia didn't play well in Sunday's embarrassing loss to the Dallas Cowboys. But in all fairness, Prescott played a massive role in ensuring the Cowboys took over the top spot in the division.

The signal-caller wasn't the most accurate, completing only 61.5% of his throws, his second-lowest mark of the year. But he still threw for 271 yards and two touchdowns. More importantly, he didn't make any glaring mistakes, something that's been an issue in the past. Prescott's next test will occur in Week 15 against Buffalo. Without question, the Bills defense can be a nightmare. Yet, many of the unit's top performers are injured, and there could be more ruled out by Sunday morning. Either way, Prescott at least warrants DFS consideration, especially since he's played so well in the last few months.

Patrick Mahomes - @ NE ($8,100)

Mahomes and the Chiefs couldn't get through the Buffalo Bills in Week 14. With the loss, Kansas City has lost their previous two games (and three of their last four), which isn't a common occurrence, especially this time of year. Of course, everyone was talking about Mahomes' sideline outburst toward the end of Sunday's loss.

But if anything, there's a good chance he'll carry that hostility into the Week 15 meeting with the Patriots. New England is easily one of the worst teams in the National Football League; the offense is a mess, and the defense isn't always reliable. With that in mind, Mahomes will be a dangerous individual in Week 15, and his rostering cost is too good to pass up.

Also Consider: Brock Purdy ($8,400), Sam Howell ($7,700), Matthew Stafford ($7,200)

FanDuel Running Backs - Week 15 DFS Lineup Picks

Bijan Robinson - @ CAR ($8,600)

Robinson, the No. 8 overall pick in the 2023 NFL Draft, has been a top fantasy back this season. While he's not at the level most were expecting heading into the 2023-24 campaign, especially for the managers who took him early in fantasy drafts, he hasn't been a bust, which is great news. Unfortunately, it took Robinson eight games before scoring his first rushing touchdown, longer than most had expected.

But since then, the former Longhorn has been getting it done, and he now has a rushing touchdown in three of his previous four appearances. Robinson will meet the Panthers for the second time in his career, with the 21-year-old going for 10 carries for 56 yards while catching all six targets for 27 yards and a score back in Week 1. Carolina isn't a good football team, and that's putting it as nicely as possible, meaning Robinson could be in line for another productive showing.

James Cook – vs. DAL ($7,200)

Cook hasn't been the most impactful rusher this season. Although he's averaging a respectable 4.8 yards per carry, he has just one touchdown on the ground. However, the 24-year-old has excelled as a pass-catcher. He currently has 38 receptions, easily surpassing his 2022-23 total.

Even better, he's found the end zone three times on the receiving end. Two of those scores have been in the last three games, and lastly, Cooks was targeted 12 times in the previous two games combined. It appears his rapport with Josh Allen is better than ever, so the duo may continue to connect in Sunday's clash with the Dallas Cowboys.

Clyde Edwards-Helaire - @ NE ($6,100)

Isiah Pacheco has been an essential piece of the Chiefs' offense all year. However, he didn't suit up in the Week 14 loss to Buffalo, and it seems he's trending toward not playing in Sunday's game in New England after missing practice on Wednesday and Thursday. If Pacheco is out for a second consecutive contest, Edwards-Helaire and Jerick McKinnon would presumably split carries.

Both logged nearly the same number of snaps against the Bills. Yet, CEH was the primary ball carrier while also seeing more looks as a pass-catcher. Granted, the former LSU Tiger wasn't the most productive fantasy option (for various reasons). But he should get plenty of opportunities to make up for it against the Pats.

Also Consider: Christian McCaffrey ($10,500), Kyren Williams ($9,600), Tony Pollard ($7,000)

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FanDuel Wide Receivers - Week 15 DFS Lineup Picks

Deebo Samuel - @ ARI ($8,400)

The 49ers hit a rough patch in October, losing three straight contests. Since then, San Francisco has won their last five games. Coincidentally enough, Samuel was injured at the beginning of that losing streak, so it's safe to say his absence played a big part in the team's struggles. That said, Samuel had one of the best games of his career in the Week 14 win over the Seattle Seahawks.

He caught seven of nine targets for 149 yards and a touchdown, amassing 21.3 yards per catch. He also ran for a score, his third straight game with a rushing touchdown. It doesn't appear anything will slow him down anytime soon. This includes the Cardinals defense, a squad that's struggled in many areas all season.

Rashee Rice - @ NE ($6,500)

Not many have exceeded expectations the way Rice has this season. The 2023 second-round pick has been on a roll all year, and he currently has six touchdowns to his credit. He'll likely add a few more before the end of the regular season. More importantly, Rice has established himself as one of Patrick Mahomes' go-to receivers, with Travis Kelce being the only guy who gets more attention consistently.

But the rookie still gets love from his signal-caller, totaling 29 targets in the last three games. DFS managers can't look in a different direction at this rate, even more so when you factor in his $6,500 rostering cost.

Also Consider: CeeDee Lamb ($9,200), Cooper Kupp ($8,200), Puka Nacua ($8,000), Terry McLaurin ($6,700), Jayden Reed ($6,100-Questionable)

FanDuel Tight Ends - Week 15 DFS Lineup Picks

Travis Kelce - @ NE ($7,500)

Kelce appears to have taken a step back this season. To be fair, he missed a few games. Still, he has only five touchdowns, so it will be tough to match his total of 12 from a season ago. But there's reason for fantasy managers to remain optimistic regarding Kelce's outlook heading into Week 15. Sure, the Patriots haven't allowed many points to opposing tight ends all year.

Then again, New England hasn't faced many (if any) quality tight ends this season, at least anyone other than Jake Ferguson, who had seven catches for 77 yards when the Cowboys demolished the Patriots back in early October. Without going out on a limb, there's no question Kelce is more talented, so the "defense versus position" should be thrown right out the window. The All-Pro is not often priced below the $8,000 mark, so get him in your lineup.

Also Consider: George Kittle ($6,800), Jake Ferguson ($5,900)

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