X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Player Comparisons
Rookies & Call-Ups
24x7 News and Alerts

DraftKings Daily Fantasy Baseball Picks (5/22/21): MLB DFS Lineups

DraftKings chopped our slates up a little bit today. There's a two game matinee "turbo" beginning at 1:05 pm Eastern. The afternoon slate with seven games starts at 4:05 Eastern. The six game "main" slate gets underway at 7:15 pm Eastern. It could be a nice, full day of baseball. Instead DraftKings chases our almighty dollars by giving us several start times to waste entry fees on. We see where their priorities lie.

This is going to cover the six game "main" slate. You can see our DraftKings and FanDuel DFS lineup pick for the early slate here as well. Coors is off the slate and so is most of the rain. The wind is blowing in at 14 mph in Dunedin, but it's not like it really matters. It was blowing in there on Thursday and there were still runs and homers galore. Expect more of the same. It's warm and humid there in Florida. We have some good hitting weather in Philly and St. Louis as well.

This article will provide you with my daily fantasy baseball lineup picks for DraftKings on 5/22/2021. The lineup will range from some of the elite players to mid-priced options and value plays. You can also check out today's FanDuel MLB DFS lineup picks and read more DFS advice and lineup picks for other sports too. It’s also important to monitor injury news and today's MLB starting lineups. If you have any questions or comments, contact me on Twitter.

Featured Promo: Get any DFS Premium Bundle for for 30% off using code NEW! Win more with expert advice from proven winners and exclusive DFS tools. Get instant access to RotoBaller's Lineup Optimizers, Research Stations, daily picks and VIP chat rooms across 10 sports! Go Premium, Win More!

 

DraftKings DFS Starting Pitchers

Walker Buehler - LAD at SF ($11,000)

Don't overthink this one. Dinelson Lamet is the long reliever for the Padres, a guy that hasn't gone more than two innings in any of his four appearances, and he's the fourth-highest priced pitcher on this slate. It's mostly garbage, so paying up for Buehler seems prudent. There's no Coors on the late, and though Dunedin is on here, there are still some reasonably priced players in that game. Buehler is the only guy on this entire slate that is guaranteed 20 DraftKings points. I think he'll clear that by a healthy mark. Buehler has never lost to the Giants in five starts and two relief appearances against them. Oh, and he's 4-0 with a 3.09 ERA at Oracle Park.

Adbert Alzolay - CHC at STL ($8,000)

The second pitcher isn't quite as easy. Yes, I'm chasing strikeouts. You can also do that with Robbie Ray, but Ray has given up 11 homers in seven starts and he's pitching in a freaking Class A ballpark. Busch Stadium is a decent hitter's park, but whereas Ray has been rather generous with baserunners, Alzolay has not. Adbert has only walked seven batters in 37 innings this year. He'll give up some long balls too, but that microscopic WHIP (0.89) keeps him from getting hurt too badly. Alzolay doesn't go very deep into games, but the strong strikeout totals and lack of baserunners make his floor the second-safest on the slate.

Other Options: Robbie Ray ($9,500), Chris Bassitt ($7,800). Justus Sheffield ($7,100)

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

DraftKings DFS Infielders

Mike Zunino - C, TB at Dunedin ($3,700)

Zunino has a pretty pathetic batting average against both lefties and righties, but what keeps us coming back against lefties is the homer every 20.5 at bats thing against southpaws. Add in the fact that Ray has been very generous with homers again this year and you have a recipe for a big score at a low price. Ray will likely give up a homer or three tonight. It's a strong bet that Zunino hits one of them.

Vladimir Guerrero Jr. - 1B, TOR vs. TB at Dunedin ($5,700)

Vlad is going to be sad when the Jays bid adieu to Dunedin. He has nine homers and 25 RBI in just 18 games there this year. That's an average of 15.6 DraftKings points per game. Not only that, the Rays are opening with young lefty Shane McClanahan, who has allowed five homers in 22.2 innings this season. He'll be good at some point, but it likely wont be at Dunedin....

Nico Hoerner - 2B, CHC at STL ($4,300)

Hoerner has done nothing but hit since the Cubs brought him up. He is hitting a cool .349 and has eight hits in the last five games. He doesn't hit for much power and is often mired at the bottom of the Cubs order, but don't let that be a deterrent. Hoerner has a .885 OPS through 18 games and he's facing a guy that hasn't seen major league action in about 18 months. Not only that, but the bullpen behind him is struggling. I like a lot of Cubs tonight.

Yandy Diaz - 1B/3B, TB at Dunedin ($3,200)

This is a cheap shot at some production here. Despite not having a home run yet this season, Diaz is still batting cleanup for the Rays. It's not a total loss. He has driven in a modest 14 runs in that spot. Diaz hasn't been held scoreless on DraftKings since May 9. I'm taking a shot on sure production against a lefty that throws batting practice between strikeouts. Diaz had 17 homers in 584 at bats prior to this season. There's some power in there somewhere.

Bo Bichette - SS, TOR vs. TB at Dunedin ($5,800)

SS is loaded on this slate. Whereas Fernando Tatis Jr. has struggled at Petco, Bichette is hitting 98 points higher at Dunedin this year. Five of his nine homers have come there in seven less games with 16 of his 27 RBI. He'll get at least one at bat against a lefty and he has hit lefties at a .331 clip in his career. Even if he doesn't get you a homer, he's getting you something.

 

DraftKings DFS Outfielders

Randy Arozarena - OF, TB at Dunedin ($5,500)

Arozarena is heating up along with the weather. He has three homers and eight RBI (not to mention seven hits and five runs scored) over the last three games. The Blue Jays were so scared of him, they walked him three times last night! Ray like to issue walks and he likes to give up home runs. Those are both right in Arozarena's wheelhouse this week.

Joc Pederson - OF, CHC at STL ($4,000)

Pederson is hitting .412 since May 5 and he finally got his first homer in that stretch last night. While the hits are nice in season-long leagues, the lack of counting stats has fantasy baseball snobs turning up their noses at Pederson. Don't do that in DFS. Hot streaks are amply rewarded in DFS since even the lowliest of hits is worth three points. Pederson's five hits in the last three games have churned out 38 DraftKings points. I want a piece of that against a rusty pitcher and struggling bullpen.

Seth Brown - OF, OAK at LAA ($2,900)

Brown hits righties hard. Tonight he gets to face one that has allowed 13 runs in his last two starts while only giving up one homer in that span! Brown has enough power to hit a homer, but I'm chasing the crooked numbers of multiple hits and runs/RBI just as much. Dylan Bundy obviously doesn't have anywhere near his best stuff right now. Brown in a great, cheap way to get exposure to a struggling pitcher.

 

DraftKings DFS Stacks

  • Tampa Bay Rays at Dunedin/Toronto Blue Jays game stack
  • Los Angeles Dodgers vs. The corpses of Scott Kazmir and Nick Tropeano. Seriously! Who knew they were grave robbers???
  • Chicago Cubs vs. Miles Mikolas
  • Boston Red Sox vs. Spencer Howard
  • Sneaky Stack: Oakland Athletics vs. Dylan Bundy



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Player Comparisons
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Rui Hachimura23 mins ago

Good To Go Against Wizards
Jamal Shead26 mins ago

Questionable For Friday Versus Chicago
LeBron James28 mins ago

Cleared For Action Thursday
Gabe Vincent33 mins ago

Remains Out Thursday
Dorian Finney-Smith37 mins ago

Out Against Wizards
Trae Young42 mins ago

Upgraded To Available Thursday
Kelly Olynyk45 mins ago

Tagged Questionable For Friday
Kaan Ofli50 mins ago

Looks For First UFC Win At UFC Saudi Arabia
Muhammad Naimov52 mins ago

Opens Up UFC Saudi Arabia Main Card
Jairzinho Rozenstruik54 mins ago

A Big Underdog At UFC Saudi Arabia
Gradey Dick56 mins ago

Questionable For Friday's Matchup With Bulls
Sergei Pavlovich58 mins ago

Looks To Snap Losing Streak At UFC Saudi Arabia
Shara Magomedov59 mins ago

Puts Undefeated Record On The Line At UFC Saudi Arabia
William Karlsson1 hour ago

To Miss Upcoming Road Trip
Michael Page1 hour ago

Moves Up To Middleweight At UFC Saudi Arabia
Immanuel Quickley1 hour ago

Listed As Questionable For Friday
Cole Sillinger1 hour ago

Rejoins Blue Jackets Lineup
Owen Tippett1 hour ago

Will Not Play On Thursday
Mikael Granlund1 hour ago

Ready To Face Kraken
Walker Kessler2 hours ago

Playing Thursday Against Minnesota
Alexander Wennberg2 hours ago

Out On Thursday
Max Scherzer2 hours ago

Signs One-Year Deal With Toronto
Mattias Ekholm2 hours ago

Good To Go Thursday
John Collins2 hours ago

Available On Thursday
Charlie McAvoy2 hours ago

Returns To Action Thursday
Dallas Goedert2 hours ago

Being Rested Again On Thursday
DeVonta Smith3 hours ago

Misses Practice Again On Thursday
Mike Conley3 hours ago

Questionable Thursday Against The Jazz
Naz Reid3 hours ago

On Track To Play On Thursday
Alexandre Sarr3 hours ago

Will Not Play Thursday
Sam Merrill3 hours ago

Uncertain For Thursday
Darius Garland3 hours ago

Not On The Injury Report
Caris LeVert4 hours ago

Remains Out On Thursday
Terry Rozier4 hours ago

Part Of Federal Investigation
Sebastian Aho4 hours ago

Questionable For Thursday
Ryker Evans4 hours ago

Day-To-Day With Upper-Body Injury
Andrei Vasilevskiy4 hours ago

Viewed As Game-Time Decision On Thursday
Linus Ullmark5 hours ago

Will Not Suit Up On Thursday
Miro Heiskanen5 hours ago

Deemed Week-To-Week
Mason Marchment5 hours ago

Hopes To Return Before International Break
Justin Tucker5 hours ago

Accused Of Inappropriate Sexual Behavior
Dylan Cease6 hours ago

Cubs A Team To Watch On Dylan Cease
Dorian Finney-Smith10 hours ago

Questionable With A Shoulder Issue
Gabe Vincent10 hours ago

In Danger Of Missing Third Consecutive Game
Rui Hachimura10 hours ago

Probable For Thursday
Dylan Cease11 hours ago

Mets Showing Interest In Dylan Cease, Michael King
Filip Gustavsson11 hours ago

Sharp In Victory Over Toronto
Sidney Crosby11 hours ago

Lifts Penguins To Victory
Quinn Hughes12 hours ago

Extends Point Streak On Wednesday
Matthew Tkachuk12 hours ago

Scores Goal, Adds Two Assists On Wednesday
Jake Allen12 hours ago

Shuts The Door On Wednesday
Owen Tippett12 hours ago

Exits Early On Wednesday
Ja'Marr Chase23 hours ago

Extension A Priority For Bengals This Offseason
Matthew Stafford23 hours ago

Plans To Play In 2025
Dallas Goedert24 hours ago

Sits Out With Ankle Injury
DeVonta Smith24 hours ago

Dealing With Hamstring Injury
Carlos Estévez24 hours ago

Carlos Estevez Signing With Kansas City
Dakota Joshua1 day ago

Rejoins Canucks Lineup Wednesday
Dylan Guenther1 day ago

Upgraded To Day-To-Day
Max Scherzer1 day ago

Blue Jays The Favorites To Land Max Scherzer
Ha-Seong Kim1 day ago

Agrees With Rays, Expected To Return In May
Ryan Pressly1 day ago

To Compete For Ninth-Inning Role In Chicago
Michael King1 day ago

Cubs Have Shown Interest In Michael King
Andrew Novak2 days ago

A Value Play At Pebble Beach
Stephan Jaeger2 days ago

A Risky Option At Pebble Beach
Adam Scott2 days ago

A Boom-Or-Bust Play At Pebble Beach
Sahith Theegala2 days ago

Looking For Bounce-Back At Pebble Beach
Russell Henley2 days ago

In Great Form Heading Into Pebble Beach
Tony Finau2 days ago

Struggles Continue Ahead Of Pebble Beach
Will Zalatoris2 days ago

Back In Action At Pebble Beach
Jason Day2 days ago

A Course Horse At Pebble Beach
Sam Burns2 days ago

In Great Form Ahead Of Pebble Beach
Hideki Matsuyama2 days ago

Looks To Stay Hot At Pebble Beach
NFL2 days ago

Mike McCarthy Won't Coach In The NFL In 2025
New Orleans Saints2 days ago

Kellen Moore In "Strong Position" To Become Saints Head Coach
Marcelo Mayer2 days ago

Roman Anthony, Kristian Campbell, Marcelo Mayer Invited To Spring Training
Jazz Chisholm Jr.2 days ago

Expected To Play Second Base In 2025
Justin Thomas2 days ago

Eyeing Victory At Pebble Beach
Detroit Lions2 days ago

Lions Hire John Morton As New Offensive Coordinator
Washington Commanders2 days ago

Kliff Kingsbury To Stay With Commanders
Cleveland Browns2 days ago

Browns Not Interested In Trading Myles Garrett
Collin Morikawa2 days ago

A Reliable Pick At AT&T Pro-Am
Scottie Scheffler2 days ago

Making Season Debut At Pebble Beach
Davis Thompson2 days ago

Treading Water Heading Into Pebble Beach
Nick Taylor2 days ago

Trending Way Up For Pebble Beach
Justin Rose2 days ago

Cannot Be Counted Out At Pebble Beach
Taylor Moore2 days ago

Attempts To Put Torrey Pines Behind Him
Shane Lowry2 days ago

Tries To Rebound After Torrey Pines
PGA2 days ago

Sungjae Im Can Contend Again At Pebble Beach
Ben Griffin2 days ago

A Bit Of An Unknown For Pebble Beach
Josiah Gray2 days ago

Begins Throwing Program, Targeting Late-Season Return
Matt Fitzpatrick2 days ago

An Intriguing Option For Pebble Beach
Russell Wilson3 days ago

Steelers Unlikely To Re-Sign Both Russell Wilson, Justin Fields
Josh Allen3 days ago

Picks Up Wrist Injury In AFC Championship Loss
A.J. Brown3 days ago

Finds The End Zone In Strong Outing
Saquon Barkley3 days ago

Posts Three-Touchdown Performance
Jalen Hurts3 days ago

Leads Explosive Offense To Super Bowl Berth
Ben Joyce3 days ago

Expected To Open Season In Closer Role
James Cook4 days ago

Scores Two Touchdowns In Loss To Chiefs
Xavier Worthy4 days ago

Leads Receivers In AFC Championship Win
Chicago Bears4 days ago

Bears Hire Dennis Allen, Declan Doyle For Coordinator Roles
Jose Altuve4 days ago

Willing To Move To Outfield
Ryan Pressly4 days ago

Traded To Cubs After Waiving No-Trade Clause
Seattle Seahawks4 days ago

Seahawks Hiring Klint Kubiak As Offensive Coordinator
Carlos Correa4 days ago

Fully Healthy Entering Spring Training
Cristian Javier4 days ago

Targeting Return After All-Star Break
Alex Bregman5 days ago

A "Long Shot" To Return To Houston
Brandon Nimmo5 days ago

Still Dealing With Plantar Fasciitis
Lance McCullers Jr.5 days ago

Luis Garcia, Lance McCullers Jr. Will Not Be Ready For Opening Day
Noah Schultz5 days ago

Invited To Spring Training
Max Scherzer5 days ago

Mets Have Interest In Reunion With Max Scherzer

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

MORE RECENT ARTICLES

 
Dak Prescott - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Five Veterans To Buy In Dynasty Fantasy Football Leagues

Managers who only play in redraft fantasy football leagues have packed it up for the season. Those who also participate in dynasty leagues know there is no offseason. Whether we're looking at the incoming rookie class, concocting trade offers, or planning for the 2025 rookie draft, we are always trying to improve. If you're in […]


Rashee Rice - Fantasy Football Rankings, NFL wr, Draft Sleepers

Five Wide Receivers To Buy In Dynasty Fantasy Football Leagues

While the 2025 fantasy football season is still months away from redraft players, dynasty players work year-round to build a winning roster. Many dynasty players fall off the radar after the regular season until the rookie draft. However, now is the perfect time to make league-winning trades. Everyone loves buy-low trade targets. Yet, sometimes, fantasy […]


Isiah Pacheco - Fantasy Football Rankings, NFL Injury News

Five Running Backs To Buy In Dynasty Fantasy Football Leagues

The great thing about competing in dynasty fantasy football leagues is that managers can make moves all offseason. Whether you are trying to compete in 2025 or entering a rebuild, making different trades in the coming months is almost a must. That's the single best way to upgrade your team for the future.  In this […]


Tucker Kraft - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Five Quarterbacks/Tight Ends To Buy In Dynasty Fantasy Football Leagues

Our Super Bowl LIX matchup is set. That means we are just about done with the 2024-25 NFL season. For dynasty fantasy football leagues, this is a slower time of year until the NFL Draft and rookie draft season are upon us in a few months. However, dynasty gamers are in a prime position to […]


Cam Ward - College Football Rankings, NCAA CFB DFS Lineup Picks

Early 2025 NFL Draft Rankings – Top 10 Quarterback Prospects

Several high-end quarterbacks, such as Jayden Daniels from LSU and Bo Nix from Oregon, were selected in the 2024 NFL Draft class. These quarterbacks have already established themselves as franchise players. However, this class does not have as many high-end options as last season, but it does have some intriguing Day 2 and Day 3 options that […]


Tetairoa McMillan - College Football DFS Lineup Picks, NCAA CFB, NFL Draft Prospect

2025 NFL Mock Draft 1.0 - Pre-Senior Bowl Mock for First Round (Matt Donnelly)

With the Senior Bowl here, the NFL Combine just a few weeks away, and the 2025 NFL Draft closing in, it's time to get our mock on and predict where some of the top players in college football will be taking their talents to in 2025 The 2025 draft class is deep and talented, with […]


Will Howard - College Football Rankings, NCAA CFB DFS Lineup Picks

Five Fantasy Football Sleepers To Target In Dynasty Rookie Drafts

With just one football game left in the season, fans of 30 of the 32 teams in the NFL have already turned their attention to the 2025 NFL Draft. Dynasty fantasy football sickos have already been focused on the draft since midseason, but it is just about time for everyone else to start paying attention. […]


Justin Jefferson - Fantasy Football rankings, NFL DFS, Injury News

Very Early 2025 Fantasy Football Rankings with Rookies and Tiers - Top 230 for Redraft Leagues

The 2024 NFL regular season just ended, but that doesn’t mean fantasy football has to. At least not totally. If you play in a dynasty or keeper league, or maybe you’re just consumed by fantasy football and cannot get enough, these 2025 fantasy football rankings should get you thinking about next season. Anytime you’re doing […]


Tyreek Hill - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Who is the Best NFL Wide Receiver Since 1990?

With the increased popularity of receivers in fantasy football and the advancement of data and film study (colossal shout-out to Reception Perception), the average football fan or fantasy football manager has more data and information at their fingertips than ever. That increased knowledge leads to more intense debates. Who is the best receiver? We could […]


Tyler Warren - College Football Rankings - NCAA CFB DFS Lineup Picks - NFL Draft

Early 2025 NFL Draft Rankings – Top 5 Tight End Prospects

The 2024 NFL Draft class had arguably the best tight end prospect in decades, if not ever. While Brock Bowers was a superstar as a rookie, the rest of the tight end class failed to make an impact. However, there is still hope for the rest of the class. Thankfully, the 2025 NFL Draft class […]


Marvin Harrison Jr. - Fantasy Football Rankings, WR, Waiver Wire, NFL DFS, Rookies

Should I Buy or Sell Marvin Harrison Jr. in Dynasty Fantasy Football Leagues?

When the Arizona Cardinals drafted wide receiver Marvin Harrison Jr. with the fourth overall pick in the 2024 NFL Draft, all fantasy managers believed Harrison was going to put up elite numbers right away. He was tabbed as a generational prospect and landed in one of the best situations. However, Harrison had his ups and […]


Video: Bold First-Round Predictions for 2025 - Way-Too-Early Fantasy Football Draft Preview

With the matchup for the Super Bowl set and the biggest game of the year just over a week away, it's a fun time to start putting together thoughts on 2025 fantasy football drafts! RotoBaller's LaQuan Jones breaks down his thoughts on 2025 in this Way-Too-Early Draft Preview. What are his bold predictions for the […]


Brian Thomas Jr - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Top Buys For Dynasty Fantasy Football – Offseason Trade Targets

The 2025 fantasy football season is still months away for redraft players. However, the game never stops for dynasty fantasy players, as the offseason is anything but slow. Now is the perfect time for fantasy players to explore the trade block and make deals ahead of free agency and dynasty rookie drafts. Everyone loves acquiring […]