Updated Week 6 Flex Rankings (Top 200)

Our updated Week 6 fantasy football Flex rankings (RB, WR, TE) for 2021. Follow these fantasy football FLEX ranks when setting your Week 6 lineups.

Welcome to Week 6 RotoBallers. Below are our updated consensus Week 6 Flex rankings for fantasy football, including some running notes on relevant injuries, player news and rankings updates. These Flex rankings are geared towards making decisions for your Flex spot (RB/WR or RB/WR/TE), which in most leagues consists of running backs, wide receivers and in many cases tight ends as well:

• Dalvin Cook Taken Off Final Injury Report
• Terry McLaurin Tweaks Hamstring, Questionable For Week 6
• Mike Williams Is Questionable To Play
• Christian McCaffrey Officially Ruled Out, Placed On IR
• Nick Chubb Ruled Out For Week 6
• Kareem Hunt Officially Listed As Questionable
• Damien Williams Tested Positive For COVID-19
• Khalil Herbert In Line For Lead Role
• Tyreek Hill Is Questionable For Week 6
• Joe Mixon In Line For Full Workload
• Samaje Perine On The COVID-19 List
• Chris Carson Ruled Out, Lands On IR
• Antonio Gibson Officially Questionable In Week 6
• Justin Jefferson, Adam Thielen Good To Go
• Jarvis Landry Activated From IR, Questionable To Play
• Zach Ertz Traded To Cardinals
• Josh Jacobs Misses Thursday's Practice With An Illness
• DeVante Parker Ruled Out
• Sterling Shepard, Darius Slayton On Track To Return

These rankings are a consensus from four of our lead fantasy football columnists - Nick Mariano, Pierre Camus, Brandon Murchison and Scott Engel - who have all analyzed the NFL matchups and game slates for Week 6.

And in case you weren't aware, our very own Nick Mariano was ranked #11 overall in 2018 out of ~120 industry experts, and was ranked #9 overall the year before. So be sure to follow his rankings every week!

• 2025 fantasy football rankings (redraft)
• Dynasty fantasy football rankings
• 2025 NFL rookie fantasy football rankings
• Best ball fantasy football rankings
• Quarterback fantasy football rankings
• Running back fantasy football rankings
• Wide receiver fantasy football rankings
• Tight end fantasy football rankings

Week 6 Fantasy Football Flex Rankings

You can also see our full Week 6 ranks for PPR, Half-PPR and Standard scoring.

Last updated on Sunday 10/17 at 11:00 am ET:

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