Updated Week 1 Flex Rankings (Top 200)

Our updated Week 1 fantasy football Flex rankings (RB, WR, TE) for 2021. Nick Mariano was ranked 9th and 11th overall out of 130 experts, follow his Flex ranks.

Welcome to Week 1 RotoBallers. Below are our updated consensus Week 1 Flex rankings for fantasy football, including some running notes on relevant injuries, player news and rankings updates. These Flex rankings are geared towards making decisions for your Flex spot (RB/WR or RB/WR/TE), which in most leagues consists of running backs, wide receivers and in many cases tight ends as well:

• Saquon Barkley Medically Cleared, Set To Return Week 1
• Austin Ekeler Expected To Play In Week 1
• Odell Beckham Jr. Likely To Play Against Chiefs
• Preston Williams Likely Out In Week 1
• A.J. Brown Good To Go For Week 1
• Kyle Rudolph Good To Go For Week 1
• Tests Confirm Torn ACL For Gus Edwards
• Le'Veon Bell Could Be Active In Week 1
• Curtis Samuel Heading To IR
• Jamison Crowder Out Week 1
• Latavius Murray Signs One-Year Deal With Baltimore
• Evan Engram Out Week 1
• Michael Gallup Out Up To Five Weeks
• Saquon Barkley Looks “Promising” Ahead Of Week 1
• Tre'Quan Smith Placed On Injured Reserve
• Jalen Hurd Ruled Out For Week 1
• Austin Ekeler Back At Practice
• Devonta Freeman Signs With Ravens Practice Squad
• Kenny Golladay Practicing Wednesday
• Clyde Edwards-Helaire 100 Percent Healthy And Ready To Go
• Darrell Henderson Fully Recovered From Thumb Injury
• Rhamondre Stevenson Not On The Injury Report
• Kadarius Toney Could Have “Significant Role” In Week 1
• Emmanuel Sanders Hopeful To Play In Opener
• Darnell Mooney Dealing With Back Injury
• Mecole Hardman Limited With Oblique Ailment
• Tre'Quan Smith No Longer On Injury Report
• Rashaad Penny Dealing With Calf Injury
• Adam Trautman Is Healthy For Week 1

These rankings are a consensus from four of our lead fantasy football columnists - Nick Mariano, Pierre Camus, Brandon Murchison and Scott Engel - who have all analyzed the NFL matchups and game slates for Week 1.

And in case you weren't aware, our very own Nick Mariano was ranked #11 overall in 2018 out of ~120 industry experts, and was ranked #9 overall the year before. So be sure to follow his rankings every week!

• 2025 fantasy football rankings (redraft)
• Dynasty fantasy football rankings
• 2025 NFL rookie fantasy football rankings
• Best ball fantasy football rankings
• Quarterback fantasy football rankings
• Running back fantasy football rankings
• Wide receiver fantasy football rankings
• Tight end fantasy football rankings

Week 1 Fantasy Football Flex Rankings

You can also see our full Week 1 ranks for PPR, Half-PPR and Standard scoring.

Last updated on Sunday 9/12 at 10:00 am ET:

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