Los Angeles Rams quarterback Matthew Stafford, Indianapolis Colts quarterback Anthony Richardson, and Tampa Bay Buccaneers quarterback Baker Mayfield are three signal-callers rostered in most fantasy leagues.
The mercurial and heavily matchup-dependent nature of QB scoring leads to weekly troubles with deciding who to start.
So let's help you decide who to put in your starting lineups for your crucial Week 16 fantasy football games.
Should I Start Matthew Stafford for Fantasy Football?
Los Angeles Rams quarterback Matthew Stafford is a solid player to start. Last week was a weird divisional matchup rain game, so you should probably ignore his low-scoring output that week. The Rams have an elite offense when it's fully healthy and when flukey, strange games aren't happening.
Matthew Stafford, you are a baaaaaad man! 😮💨#ProBowlVote | More highlights on https://t.co/m9oFPQ096a 🎥 pic.twitter.com/RbVTQRt2hq
— Los Angeles Rams (@RamsNFL) December 9, 2024
Stafford, his elite receivers, and his elite head coach Sean McVay diced up the Buffalo Bills' defense two weeks ago. They'll now face a New York Jets defense that's completely imploded after the firing of former head coach Robert Saleh. The 36-year-old signal-caller can be started with confidence as a low-end QB1.
Should I Start Anthony Richardson for Fantasy Football?
He's being completely carried by his rushing numbers right now, but that's good enough for fantasy football. He's also rushed 10, 10, nine, and seven times each in his last four games -- consistency on that front will be key to maintaining his value moving forward. And the four rushing scores over that span don't hurt either.
Anthony Richardson : 17/38 for 172 yards, 2 INT's & a 36.3 QB Rating; 7 carries for 46 yards & a TD pic.twitter.com/37H8UZ4h5S
— Lee Harvey (@MusikFan4Life) December 16, 2024
He is simply not a good passer. But it doesn't really matter. As long as he can stay healthy, he's a solid QB to start and fits in the low-end QB1 range, though with more risk. If he doesn't get a rush TD, he probably won't have a great game, and you can see that his games without running scores are usually not great.
Should I Start Baker Mayfield for Fantasy Football?
Yes. He's the QB5 on the year, and despite the team losing wide receiver Chris Godwin (ankle) to a season-ending ankle injury much earlier in the season, Mayfield has continued to produce well. He's playing fantastic football, and his offensive coordinator, Liam Coen, is one of the best in the NFL.
BAKER MAYFIELD WITH ONE OF THE CRAZIEST PLAYS OF THE YEAR.
HAVE NEVER SEEN ANYTHING LIKE THIS. WOW.
🤯🤯🤯
— MLFootball (@_MLFootball) November 10, 2024
He's an elite QB this year. He'll face a Dallas Cowboys defense that's suffering from a ton of key injuries. Start him in all leagues.
Popular Week 16 Searches - Start/Sit Comparisons
Below are some popular Week 16 searches and comparisons from our Who To Start tool for Matthew Stafford, Anthony Richardson, Baker Mayfield compared to others. You can also use the free Who Should I Start tool to run your own start/sit comparisons, up to four players at once:
Justin Herbert or Anthony Richardson
Jared Goff or Baker Mayfield
Jayden Daniels or Baker Mayfield
Bo Nix or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Bo Nix or Matthew Stafford
Joe Burrow or Baker Mayfield
Brock Purdy or Matthew Stafford
Jordan Love or Baker Mayfield
Lamar Jackson or Baker Mayfield
Cj Stroud or Matthew Stafford
Jordan Love or Anthony Richardson
Caleb Williams or Matthew Stafford
Tua Tagovailoa or Anthony Richardson
Anthony Richardson or Matthew Stafford
Justin Herbert or Matthew Stafford
Bo Nix or Baker Mayfield
Drake Maye or Anthony Richardson
Aaron Rodgers or Matthew Stafford
Drake Maye or Matthew Stafford
Jalen Hurts or Baker Mayfield
Cooper Rush or Anthony Richardson
Patrick Mahomes or Matthew Stafford
Brock Purdy or Anthony Richardson
Jayden Daniels or Matthew Stafford
Russell Wilson or Anthony Richardson
Matthew Stafford or Anthony Richardson
Jordan Love or Matthew Stafford
Patrick Mahomes or Anthony Richardson
Brock Purdy or Baker Mayfield
Caleb Williams or Anthony Richardson
Sam Darnold or Matthew Stafford
Matthew Stafford or Anthony Richardson
Kyler Murray or Anthony Richardson
Kyler Murray or Baker Mayfield
Sam Darnold or Baker Mayfield
Bo Nix or Matthew Stafford
Jared Goff or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Jayden Daniels or Anthony Richardson
Russell Wilson or Matthew Stafford
Sam Darnold or Anthony Richardson
Baker Mayfield or Matthew Stafford
Cj Stroud or Anthony Richardson
Jameis Winston or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Geno Smith or Anthony Richardson
Justin Herbert or Baker Mayfield
Mac Jones or Matthew Stafford
Michael Penixjr or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Bo Nix or Anthony Richardson
Jared Goff or Anthony Richardson
Joe Burrow or Matthew Stafford
Justin Herbert or Anthony Richardson
Justin Herbert or Matthew Stafford
Lamar Jackson or Matthew Stafford
Aaron Rodgers or Baker Mayfield
Baker Mayfield or Anthony Richardson
Brock Purdy or Matthew Stafford
Cj Stroud or Matthew Stafford
Jared Goff or Anthony Richardson
Jared Goff or Anthony Richardson
Jayden Daniels or Baker Mayfield
Jordan Love or Matthew Stafford
Justin Herbert or Anthony Richardson
Kyler Murray or Matthew Stafford
Mason Rudolph or Anthony Richardson
Matthew Stafford or Baker Mayfield
Michael Penixjr or Matthew Stafford
Patrick Mahomes or Baker Mayfield
Russell Wilson or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Bo Nix or Anthony Richardson
Jalen Hurts or Matthew Stafford
Jared Goff or Anthony Richardson
Kirk Cousins or Matthew Stafford
Kyler Murray or Matthew Stafford
Malik Nabers or Matthew Stafford
Patrick Mahomes or Anthony Richardson
Patrick Mahomes or Matthew Stafford
Sam Darnold or Baker Mayfield
Sam Darnold or Matthew Stafford
Tua Tagovailoa or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Baker Mayfield
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aidan Oconnell or Anthony Richardson
Aidan Oconnell or Matthew Stafford
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Baker Mayfield
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Brock Purdy or Anthony Richardson
Brock Purdy or Anthony Richardson
Brock Purdy or Matthew Stafford
Cj Stroud or Baker Mayfield
Cj Stroud or Matthew Stafford
Drake Maye or Matthew Stafford
Geno Smith or Anthony Richardson
Geno Smith or Matthew Stafford
Jameis Winston or Anthony Richardson
Jared Goff or Matthew Stafford
Jayden Daniels or Baker Mayfield
Jayden Daniels or Matthew Stafford
Jordan Addison or Matthew Stafford
Jordan Love or Anthony Richardson
Jordan Love or Baker Mayfield
Jordan Love or Matthew Stafford
Jordan Love or Matthew Stafford
Jordan Love or Matthew Stafford
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Baker Mayfield
Justin Herbert or Matthew Stafford
Keenan Allen or Anthony Richardson
Kyler Murray or Anthony Richardson
Kyler Murray or Baker Mayfield
Mason Rudolph or Matthew Stafford
Matthew Stafford or Anthony Richardson
Matthew Stafford or Anthony Richardson
Michael Penixjr or Matthew Stafford
Rayray Mccloudiii or Baker Mayfield
Rhamondre Stevenson or Baker Mayfield
Sam Darnold or Baker Mayfield
Travis Etiennejr or Anthony Richardson
Tua Tagovailoa or Anthony Richardson
Tua Tagovailoa or Anthony Richardson
Tua Tagovailoa or Anthony Richardson
Tua Tagovailoa or Anthony Richardson
Tua Tagovailoa or Baker Mayfield
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Anthony Richardson
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aaron Rodgers or Matthew Stafford
Aidan Oconnell or Anthony Richardson
Aj Brown or Baker Mayfield
Alvin Kamara or Matthew Stafford
Anthony Richardson or Baker Mayfield
Anthony Richardson or Matthew Stafford
Anthony Richardson or Matthew Stafford
Anthony Richardson or Matthew Stafford
Anthony Richardson or Matthew Stafford
Anthony Richardson or Matthew Stafford
Anthony Richardson or Matthew Stafford
Baker Mayfield or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Anthony Richardson
Bo Nix or Baker Mayfield
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Bo Nix or Matthew Stafford
Brock Purdy or Anthony Richardson
Brock Purdy or Anthony Richardson
Brock Purdy or Baker Mayfield
Brock Purdy or Baker Mayfield
Brock Purdy or Matthew Stafford
Brock Purdy or Matthew Stafford
Brock Purdy or Matthew Stafford
Brock Purdy or Matthew Stafford
Brock Purdy or Matthew Stafford
Brock Purdy or Matthew Stafford
Caleb Williams or Anthony Richardson
Caleb Williams or Anthony Richardson
Caleb Williams or Matthew Stafford
Caleb Williams or Matthew Stafford
Caleb Williams or Matthew Stafford
Carson Wentz or Matthew Stafford
Christian Watson or Anthony Richardson
Cj Stroud or Anthony Richardson
Cj Stroud or Anthony Richardson
Cj Stroud or Anthony Richardson
Cj Stroud or Baker Mayfield
Cj Stroud or Matthew Stafford
Cj Stroud or Matthew Stafford
Cj Stroud or Matthew Stafford
Cooper Kupp or Anthony Richardson
Cooper Rush or Anthony Richardson
Cooper Rush or Matthew Stafford
Cooper Rush or Matthew Stafford
Dandre Swift or Baker Mayfield
Davante Adams or Matthew Stafford
Derek Carr or Matthew Stafford
Devon Achane or Anthony Richardson
Dj Moore or Anthony Richardson
Dj Moore or Anthony Richardson
Dj Moore or Matthew Stafford
Drake Maye or Anthony Richardson
Drake Maye or Anthony Richardson
Drake Maye or Anthony Richardson
Drake Maye or Matthew Stafford
Drake Maye or Matthew Stafford
Drake Maye or Matthew Stafford
Gus Edwards or Matthew Stafford
Isiah Pacheco or Matthew Stafford
Jalen Hurts or Anthony Richardson
Jalen Hurts or Baker Mayfield
Jalen Hurts or Baker Mayfield
Jalen Mcmillan or Baker Mayfield
Jameis Winston or Anthony Richardson
Jameis Winston or Anthony Richardson
Jameis Winston or Anthony Richardson
Jared Goff or Anthony Richardson
Jared Goff or Baker Mayfield
Jaxon Smithnjigba or Anthony Richardson
Jayden Daniels or Baker Mayfield
Jayden Daniels or Baker Mayfield
Jayden Daniels or Baker Mayfield
Jayden Daniels or Baker Mayfield
Jayden Daniels or Baker Mayfield
Jerome Ford or Anthony Richardson
Joe Burrow or Anthony Richardson
Joe Burrow or Baker Mayfield
Joe Burrow or Baker Mayfield
Joe Mixon or Matthew Stafford
Jordan Love or Anthony Richardson
Jordan Love or Anthony Richardson
Jordan Love or Anthony Richardson
Jordan Love or Anthony Richardson
Jordan Love or Baker Mayfield
Jordan Love or Matthew Stafford
Jordan Love or Matthew Stafford
Jordan Love or Matthew Stafford
Joshua Dobbs or Baker Mayfield
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Anthony Richardson
Justin Herbert or Baker Mayfield
Justin Herbert or Baker Mayfield
Justin Herbert or Matthew Stafford
Justin Herbert or Matthew Stafford
Justin Herbert or Matthew Stafford
Justin Herbert or Matthew Stafford
Kaimi Fairbairn or Baker Mayfield
Khalil Shakir or Matthew Stafford
Kirk Cousins or Anthony Richardson
Kirk Cousins or Anthony Richardson
Kyler Murray or Baker Mayfield
Kyler Murray or Matthew Stafford
Kyler Murray or Matthew Stafford
Kyler Murray or Matthew Stafford
Kyler Murray or Matthew Stafford
Kyler Murray or Matthew Stafford
Kyler Murray or Matthew Stafford
Lamar Jackson or Anthony Richardson
Lamar Jackson or Baker Mayfield
Lamar Jackson or Baker Mayfield
Lamar Jackson or Baker Mayfield
Lamar Jackson or Baker Mayfield
Mac Jones or Anthony Richardson
Mac Jones or Anthony Richardson
Matthew Stafford or Anthony Richardson
Matthew Stafford or Anthony Richardson
Matthew Stafford or Anthony Richardson
Matthew Stafford or Anthony Richardson
Matthew Stafford or Matthew Stafford
Michael Penixjr or Anthony Richardson
Michael Penixjr or Anthony Richardson
Michael Penixjr or Matthew Stafford
Michael Penixjr or Matthew Stafford
Michael Penixjr or Matthew Stafford
Patrick Mahomes or Anthony Richardson
Patrick Mahomes or Anthony Richardson
Patrick Mahomes or Anthony Richardson
Patrick Mahomes or Anthony Richardson
Russell Wilson or Matthew Stafford
Sam Darnold or Anthony Richardson
Sam Darnold or Anthony Richardson
Sam Darnold or Anthony Richardson
Sam Darnold or Baker Mayfield
Sam Darnold or Matthew Stafford
Sam Darnold or Matthew Stafford
Sam Darnold or Matthew Stafford
Saquon Barkley or Baker Mayfield
Tua Tagovailoa or Anthony Richardson
Tua Tagovailoa or Anthony Richardson
Tua Tagovailoa or Anthony Richardson
Tua Tagovailoa or Baker Mayfield
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
Tua Tagovailoa or Matthew Stafford
More Fantasy Football Start 'Em, Sit 'Em Picks
Who Should I Start for Fantasy Football Week 16? Aaron Rodgers, Kyler Murray, Sam Darnold
We are only a few days away from fantasy football championship week. That means you can be sure that fantasy owners everywhere are going through their lineups with a fine-toothed comb. Quarterbacks are always essential to a high-scoring fantasy week. Picking the right signal-caller can give your team the advantage you need. Several quarterbacks that […]
Who Should I Start for Fantasy Football Week 16? Bills D/ST, Bengals D/ST, Cardinals D/ST
We only have two weeks left in the fantasy football season. That means it’s important that gamers evaluate every position in their starting lineups, including team defenses. Fantasy football D/STs can really bail you out with a crooked number if several of your regular starters flop. That’s why gamers should make certain they are choosing […]
Who Should I Start for Fantasy Football Week 16? Jonnu Smith, Brenton Strange, Tucker Kraft
The fantasy football playoffs are in full swing and every start or sit decision becomes that much more important as your team advances to the next round. The margin for error is small when it comes to playoff matchups. Unless you have a player or two go off, you simply need some solid production from […]
Who Should I Start for Fantasy Football Week 16? Falcons D/ST, Packers D/ST, Colts D/ST
Fantasy players everywhere are vying for a spot in their league’s championship game. With so much at stake, every lineup decision is more important than ever. An area gamers often focus on is which D/ST they should start. Sometimes managers can get so consumed with keeping one D/ST on their roster that they overlook other […]
Who Should I Start for Fantasy Football Week 16? Breece Hall, Tony Pollard, Tyrone Tracy Jr.
It's hard to find consistently good running backs in fantasy football. Each year, there are only a few that have zero games with less than double-digit PPR fantasy points. This year, there are none, though, since Baltimore Ravens running back Derrick Henry finally logged his first game of just single-digit scoring. So it's always worth […]
Download Our Free News & Alerts Mobile App
Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!