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21 seconds agoSan Francisco 49ers quarterback Brock Purdy (shoulder) has been ruled out for Week 12, but the team believes he'll be able to play next weekend against the Buffalo Bills. Purdy's progress was inconsistent earlier this week, and the team did think he'd be able to suit up against the Green Bay Packers before ruling him out. Fantasy managers should expect all Niners playmakers to take a step back in terms of fantasy production. Meanwhile, interim starter Brandon Alle will rank as a low-end QB2.--Andersen Pickard - RotoBaller
Source: Adam Schefter

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