Fantasy Football Running Back Injury Reports: Week 12 Updates for Isiah Pacheco, Josh Jacobs, D'Andre Swift, Alexander Mattison

Below is our fantasy football injuries report for running backs in Week 12, as of November 23. The injury statuses for various NFL running backs are up in the air for Week 12, including Isiah Pacheco, Josh Jacobs, D'Andre Swift, and Alexander Mattison.

As the fantasy football season continues, every decision, transaction, and lineup change matters. These are critical running back injuries to keep track of throughout the week. Being up-to-date on NFL injury news can give you an edge over your league mates in fantasy football.

To keep close tabs on all the news across the NFL, favorite or bookmark the fantasy football player news page, or download the free RotoBaller fantasy football mobile app with push notification alerts on all the latest news. Let's look at the updates for some running backs and see whether they may play in Week 12.

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Isiah Pacheco Injury Update

As expected, Pacheco (ankle) will not play in Week 12 against the Panthers. He had made significant progress this week, but the expectation in Kansas City was that he would be held out one more game. Kareem Hunt should get an additional opportunity to lead the Chiefs' backfield on Sunday.

Here's the final injury report for the Chiefs and Panthers. pic.twitter.com/2gwu1lTs1d

— Matt McMullen (@KCChiefs_Matt) November 22, 2024

Josh Jacobs Injury Update

Jacobs (quadricep, calf) was limited in practice all week long, but he has been removed from the injury report and will play against the 49ers on Sunday. The veteran is a solid RB1 option for fantasy football.

Full injury report for Sunday’s 49ers-Packers game: pic.twitter.com/QVPpVHwlBe

— Adam Schefter (@AdamSchefter) November 22, 2024

D'Andre Swift Injury Update

Swift (groin) practiced in full on Friday, but he's still listed as questionable to play against the Vikings. Fantasy managers should view him as an RB2 option, assuming he suits up on Sunday.

The final Vikings-Bears injury report... pic.twitter.com/52Lsav8LCO

— Alec Lewis (@alec_lewis) November 22, 2024

Alexander Mattison Injury Update

Mattison (ankle) is doubtful to play in Week 12 after missing three consecutive practices. With both Mattison and Zamir White (quadricep) likely sidelined on Sunday, look for Ameer Abdullah to lead the Las Vegas backfield. Rookie Dylan Laube should also earn additional opportunities.

Raiders/Broncos Fri Injury Report #Raiders pic.twitter.com/rbXc8Omt2z

— Your Boy Q (@YourboyQ254) November 22, 2024

Tyjae Spears Injury Update

Spears (concussion) has been ruled out for Week 12 despite being upgraded to a limited participant in practice on Friday. Julius Chestnut will once again operate as the backup to Tony Pollard.

Titans #TENvsHOU Injury Report @FBHealthPlans pic.twitter.com/im5nOc9bSs

— Tennessee Titans (@Titans) November 22, 2024

Jonathon Brooks Injury Update

Brooks (knee) is questionable for Week 12 against the Chiefs. He logged another full week of practice, but the Panthers aren't quite ready to confirm he'll make his NFL debut. With that said, the overarching belief is that he'll play, operating behind Chuba Hubbard.

Here's the final injury report for the Chiefs and Panthers. pic.twitter.com/2gwu1lTs1d

— Matt McMullen (@KCChiefs_Matt) November 22, 2024

Justice Hill Injury Update

Hill (concussion) was able to log a full practice on Friday. The Ravens still have one more day before they need to issue injury designations, but it looks like Hill is trending in the right direction. He'd rank as a low-end fantasy RB3 if confirmed as active for Week 12.

Friday's injury report: pic.twitter.com/zToyDLaOue

— Baltimore Ravens (@Ravens) November 22, 2024

Zamir White Injury Update

White (quadricep) is doubtful to play in Week 12 after missing three consecutive practices. With both White and Alexander Mattison (ankle) likely sidelined on Sunday, look for Ameer Abdullah to lead the Las Vegas backfield. Rookie Dylan Laube should also earn additional opportunities.

Raiders/Broncos Fri Injury Report #Raiders pic.twitter.com/rbXc8Omt2z

— Your Boy Q (@YourboyQ254) November 22, 2024

Emari Demercado Injury Update

Demercado (shoulder) will play in Week 12 after being upgraded to a full participant on Friday. He figures to remain in a depth role with Trey Benson behind James Conner.

Jalen Thompson is officially out for Sunday's game against the Seahawks. Darius Robinson and Jonah Williams are both questionable.

Full Cardinals-Seahawks injury report: pic.twitter.com/OCVqFmAEaW

— Theo Mackie (@theo_mackie) November 22, 2024

Miles Sanders Injury Update

Sanders (ankle) has been ruled out for Week 12 after missing three practices in a row. The veteran running back's absence will lead to additional opportunities for Hubbard and (possibly) Brooks.

Here's the final injury report for the Chiefs and Panthers. pic.twitter.com/2gwu1lTs1d

— Matt McMullen (@KCChiefs_Matt) November 22, 2024

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