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2 months agoHouston Texans running back Joe Mixon (ankle) is still regarded as week-to-week due to an ankle injury that kept him out of the Week 3 loss to the Minnesota Vikings, according to sources. It's no lock that Mixon is able to return to action in Week 4 versus the division-rival Jacksonville Jaguars. We'll have a better idea of Mixon's status for this Sunday's game later in the week. Dameon Pierce (hamstring) hasn't played the last two weeks, but he's trending in the right direction and is expected to return in Week 4. So if Mixon misses a second straight game, both Pierce and Cam Akers figure to split Houston's backfield against the 0-3 Jaguars. Fantasy managers that used Mixon in their starting lineups the first two weeks of the season need to plan as though he'll miss another game this weekend. This is your cue to check the waiver wire and add Pierce if you're in dire straights at the RB position. UPDATE: Mixon did not practice on Wednesday.--Keith Hernandez - RotoBaller
Source: KPRC 2 Sports - Aaron Wilson

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