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Top MLB Betting Picks for Today's Slate (5/24/19)

Nate Duffett's MLB betting picks for 5/24/19. He analyzes Vegas lines and recommends the top expert bets for today's MLB slate including moneylines and over/unders.

Welcome back RotoBallers! On Friday, May 24th, we see a huge 15 game MLB slate. The day starts with a 2:20 PM game between the Cincinnati Reds and Chicago Cubs, and ends with a 10:15 PM game between the Arizona Diamondbacks and San Francisco Giants.

In this article, we will dive into the numbers and pick out my top recommended betting picks for today's slate. Feel free to hit me up on Twitter @Roto_Nate if you have any questions.

So without any further delay, below are my picks for Friday, May 24th. Good luck!

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San Diego Padres (-120) @ Toronto Blue Jays | O/U: 8.5

Both of these teams are 4-6 in their last ten, but the Padres seem to be breaking out, winning three in a row against the Diamondbacks. The Blue Jays lost three of four to the Red Sox and have been looking terrible despite a breakout offensive game on Tuesday. The Blue Jays haven't looked good at home, only managing an 8-16 record at home while the Padres have gone 12-10 on the road. I'm guessing the odds are lower due to the possible jet lag the Padres will be experiencing after the cross-continent travel, but I feel the talent should outweigh that problem today. If jetlag is a worry for you, by all means, stay away. However, I will be all over the Padres.

My Pick: Padres (-120)

 

Cincinnati Reds @ Chicago Cubs (-155) | O/U: 8.5

This is one of those picks that seems too easy, which is something that scares me, but I will be locking it in regardless. The Cubs are 17-8 at home while the Reds are 10-16 on the road. The Reds are sending Anthony DeSclafani to the mound, who has allowed 11 earned runs over his past three starts. Kyle Hendricks is the counter for the Cubs, allowing one or fewer runs in three of his last four starts, including a start against the Reds 10 days ago when he allowed one earned run over eight innings of work. I'm backing the Cubs to win big at Wrigley today.

My Pick: Cubs -1.5 (+135) 

 

 Boston Red Sox (-146) @ Houston Astros | O/U: 8.5

If last weeks series between these two teams is any indication, a Chris Sale game is the only time when the Astros will be underdogs over this weekend set. I think they are giving Sale too much credit in this matchup, as the Astros are the best team against left-handed pitching in the league with a .382 wOBA. The Astros are also 7-3 over their last ten games and 18-6 at home.

My Pick: Astros (+135)

 

Texas Rangers @ Los Angeles (-158) | O/U: 9

As much as I hate to back a team that has Drew Smyly taking the mound, I will hope that he can give us four or five good innings and then make way for the bullpen. This is a possibility as the Angels are one of the worst teams in the league against left-handed pitching with a .285 wOBA. On the other hand, the Rangers are the second-best team against right-handed pitching with a .355 wOBA so they should be able to get to Griffin Canning tonight. The Rangers are 7-3 in their last 10, while the Angels are 3-7. The odds are too good for me not to take a chance on the red-hot Rangers.

My Pick: Rangers (+148)

 

Chicago White Sox @ Minnesota Twins (-210) | O/U: 9

The Twins have racked up 67 runs over their past seven games, and they face Reynaldo Lopez and his 5.14 ERA today. I think they could cover the over by themselves today, but Jose Berrios has also allowed nine runs over his last two starts, so the White Sox should contribute some runs as well. I can't believe we can get this number at 9 with the way the Twins have been tearing the cover off of the ball and Berrios' recent form. One worry is that Lopez has been doing well recently, but he did that in starts against the Jays and Indians, who are two of the worst hitting teams in the league so far this season.

My Pick: Over 9 

More Fantasy Baseball Analysis




REAL-TIME FANTASY NEWS

Cade Otton

Remains a Quality Dynasty Depth Piece
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
Austin Reaves

Scores 31 Points in Game 2 Defeat
T.J. Hockenson

Bounce-Back Chances Stifled by Improved Pass-Catching Depth
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
Chet Holmgren

Anchors Thunder Past Lakers in Game 2
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
Jordan Addison

Facing Competition for No. 2 Role?
Tobias Harris

Stays Hot in Game 2 Victory
Cade Cunningham

Pushes Pistons to 2-0 Series Lead
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
Taylor Heinicke

Retiring After 11 Seasons
Jarrett Allen

Provides Bright Spot in Cavs' Game 2 Loss to Pistons
Jauan Jennings

Signs With Vikings on One-Year Deal
CFB

Rasheem Biles an Instant Impact Player for Texas
James Harden

Struggles in Game 2 Loss
Donovan Mitchell

Finishes Game 2 Loss with 31 Points
Gradey Dick

Open to Trade Away From Toronto
Michael Porter Jr.

Wants to Stay in Brooklyn
Charlotte Hornets

Hornets Extend Charles Lee After 25-Win Improvement
Jarred Vanderbilt

Ruled Out for Game 2 Against Thunder
Luke Kennard

Cleared to Play Thursday
Ayo Dosunmu

Considered Questionable for Game 3 Against Spurs
Anthony Edwards

Remains Questionable on Injury Report Ahead of Game 3
Mitchell Robinson

Probable for Friday's Action
Kevin Huerter

Remains Out Thursday
Sam Merrill

Unavailable Thursday
OG Anunoby

Tagged as Questionable for Friday
Joel Embiid

Listed as Questionable for Game 3 Against Knicks
Dan Vladar

Looks to Return to Winning Ways Thursday
Connor Dewar

Penguins Re-Sign Connor Dewar for Two Years
Mikko Rantanen

Played Through Torn MCL Late in the Season
Rasmus Dahlin

Ready to Go Friday
Kyle Pitts Sr.

Signs Franchise Tender on Thursday
Alexander Nikishin

Set to Return Thursday
Joe Burrow

Attending Voluntary Workouts, Ready for Monster Season?
Christian Dvorak

Available Thursday
Owen Tippett

Remains Out Thursday
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
T.J. Hockenson

Can T.J. Hockenson Bounce Back with Improved Quarterback Play in Minnesota?
Jordan Love

Is Jordan Love's Dynasty Upside Fading Entering 2026?
Dalton Schultz

Facing Increased Playing Time Competition in Houston Entering 2026
Kimani Vidal

Dynasty Value in Question Due to Uncertain Playing Time Outlook
Juwan Johnson

Facing Reduced Role in New Orleans Following NFL Draft?
Chuba Hubbard

a Prime Bounce-Back Candidate Following Offseason Moves
Indianapolis Colts

Kenny Moore Granted his Release by Colts
Minnesota Vikings

Chad Alexander a Candidate for Vikings GM Job
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Minnesota Vikings

Vikings Request to Interview RJ Gillen for GM Job
Drake Maye

Shoulder Doing "Great"
Gunnar Helm

a Clear Breakout Candidate Despite Crowded Offense?
Travis Hunter

Dynasty Managers Regret Drafting Travis Hunter?
Khalil Shakir

Offseason Addition a Threat to Khalil Shakir's Consistency?
Christian Watson

Can Christian Watson Overcome Injury History?
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Paul George

Does a Little Bit of Everything in Game 2 Loss
Tyrese Maxey

Tallies Team-High 26 Points in Wednesday's Loss
Mark Stone

Nets Late Power-Play Goal in Losing Effort
Leo Carlsson

Pots Game-Winner Wednesday Night
Juraj Slafkovsky

Ends Point Drought in Game 1 Loss
Bowen Byram

Ties Franchise Record With Fourth Postseason Goal
Zach Benson

Posts Second Consecutive Multi-Point Game
Rasmus Dahlin

"Seems Fine" After Early Exit on Wednesday
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Nils Hoglander

Will Miss World Championship Due to Injury
Christian Dvorak

Likely to Play in Game 3 Against Hurricanes
Owen Tippett

a Game-Time Decision Thursday
Noah Cates

to Miss Rest of Round 2
Arber Xhekaj

Rejoins Canadiens Lineup Wednesday
Brendan Gallagher

Scratched on Wednesday
Logan Stanley

Returns to Action Wednesday
Framber Valdez

Suspended Six Games
Tyler Glasnow

Exits Early on Wednesday With Back Pain
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Brandon Woodruff

has Fluid Drained From his Right Shoulder
Brandon Woodruff

to Resume Throwing on Saturday, Return Imminent?
Carlos Correa

to Have Season-Ending Ankle Surgery
Jacob Misiorowski

Listed as Friday's Probable Starter
Logan Webb

Dealing With Knee Discomfort
Carlos Correa

Expected to Miss Significant Time With Ankle Injury
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Mats Zuccarello

Extends Point Streak to Five Games
Emilio Pagán

Emilio Pagan Headed for Injured List With Hamstring Injury
Emilio Pagán

Emilio Pagan Carted Off With Apparent Hamstring Injury on Tuesday
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
MLB

Cardinals-Brewers Game Postponed on Tuesday
Roman Anthony

Day-to-Day With Wrist Sprain
Jacob Misiorowski

"All Things Look Good" for Jacob Misiorowski to Start on Wednesday
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
MLB

Rockies-Mets Game Postponed Due to Inclement Weather
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Tim Elliott

Drops Decision At UFC Perth
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
William Byron

Might have the Speed to Compete for the Win at Texas
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Tyler Reddick

One of the Favorites to Win at Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
RANKINGS
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OF
SP
RP

RANKINGS

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K
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