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Top MLB Betting Picks for Today's Slate (5/24/19)

Nate Duffett's MLB betting picks for 5/24/19. He analyzes Vegas lines and recommends the top expert bets for today's MLB slate including moneylines and over/unders.

Welcome back RotoBallers! On Friday, May 24th, we see a huge 15 game MLB slate. The day starts with a 2:20 PM game between the Cincinnati Reds and Chicago Cubs, and ends with a 10:15 PM game between the Arizona Diamondbacks and San Francisco Giants.

In this article, we will dive into the numbers and pick out my top recommended betting picks for today's slate. Feel free to hit me up on Twitter @Roto_Nate if you have any questions.

So without any further delay, below are my picks for Friday, May 24th. Good luck!

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San Diego Padres (-120) @ Toronto Blue Jays | O/U: 8.5

Both of these teams are 4-6 in their last ten, but the Padres seem to be breaking out, winning three in a row against the Diamondbacks. The Blue Jays lost three of four to the Red Sox and have been looking terrible despite a breakout offensive game on Tuesday. The Blue Jays haven't looked good at home, only managing an 8-16 record at home while the Padres have gone 12-10 on the road. I'm guessing the odds are lower due to the possible jet lag the Padres will be experiencing after the cross-continent travel, but I feel the talent should outweigh that problem today. If jetlag is a worry for you, by all means, stay away. However, I will be all over the Padres.

My Pick: Padres (-120)

 

Cincinnati Reds @ Chicago Cubs (-155) | O/U: 8.5

This is one of those picks that seems too easy, which is something that scares me, but I will be locking it in regardless. The Cubs are 17-8 at home while the Reds are 10-16 on the road. The Reds are sending Anthony DeSclafani to the mound, who has allowed 11 earned runs over his past three starts. Kyle Hendricks is the counter for the Cubs, allowing one or fewer runs in three of his last four starts, including a start against the Reds 10 days ago when he allowed one earned run over eight innings of work. I'm backing the Cubs to win big at Wrigley today.

My Pick: Cubs -1.5 (+135) 

 

 Boston Red Sox (-146) @ Houston Astros | O/U: 8.5

If last weeks series between these two teams is any indication, a Chris Sale game is the only time when the Astros will be underdogs over this weekend set. I think they are giving Sale too much credit in this matchup, as the Astros are the best team against left-handed pitching in the league with a .382 wOBA. The Astros are also 7-3 over their last ten games and 18-6 at home.

My Pick: Astros (+135)

 

Texas Rangers @ Los Angeles (-158) | O/U: 9

As much as I hate to back a team that has Drew Smyly taking the mound, I will hope that he can give us four or five good innings and then make way for the bullpen. This is a possibility as the Angels are one of the worst teams in the league against left-handed pitching with a .285 wOBA. On the other hand, the Rangers are the second-best team against right-handed pitching with a .355 wOBA so they should be able to get to Griffin Canning tonight. The Rangers are 7-3 in their last 10, while the Angels are 3-7. The odds are too good for me not to take a chance on the red-hot Rangers.

My Pick: Rangers (+148)

 

Chicago White Sox @ Minnesota Twins (-210) | O/U: 9

The Twins have racked up 67 runs over their past seven games, and they face Reynaldo Lopez and his 5.14 ERA today. I think they could cover the over by themselves today, but Jose Berrios has also allowed nine runs over his last two starts, so the White Sox should contribute some runs as well. I can't believe we can get this number at 9 with the way the Twins have been tearing the cover off of the ball and Berrios' recent form. One worry is that Lopez has been doing well recently, but he did that in starts against the Jays and Indians, who are two of the worst hitting teams in the league so far this season.

My Pick: Over 9 

More Fantasy Baseball Analysis




REAL-TIME FANTASY NEWS

Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Luke Kornet

Iffy for Monday
Larry Nance Jr.

Won't Play Sunday
De'Aaron Fox

Listed as Questionable for Monday's Action
Jalen Williams

Officially Available for Game 1 Against Spurs
Shai Gilgeous-Alexander

Named MVP for Second Straight Year
Jonah Coleman

is an Intriguing Power Back to Target in Dynasty Leagues
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Darius Slayton

Lacking Long-Term Upside for Dynasty Managers
Keaton Mitchell

a Prime Dynasty Handcuff Option Entering First Season in L.A.
Jadarian Price

Looks Like the Running Back of the Future in Seattle
Isaiah Bond

Dynasty Outlook Clouded by Uncertain Role in Cleveland
James Cook III

Remains a High-End Dynasty RB1 Entering 2026
Lamar Jackson

Poised for Bounce Back Season in 2026
Bucky Irving

Expected to Be Ready for Training Camp
Kyle Williams

Deep Threat Kyle Williams Facing Uphill Battle for Playing Time
Michael Pittman Jr.

Could Receive Short-Term Value Uptick in PPR Leagues
Stefon Diggs

Chiefs, Commanders Could Make Sense for Stefon Diggs
Will Howard

Dynasty Value Dealt a Blow
Jaylen Warren

Should Benefit From Veteran QB's Return to Pittsburgh
Drew Allar

Could Continue to Hold Dynasty Value
Pat Freiermuth

Could See a Small Dynasty Bump With Veteran QB Returning
DK Metcalf

A Dynasty Sell Candidate With Veteran QB Returning?
Bones Hyland

Wants to Stay in Minnesota
Mike Conley

Hints He Will Continue Playing Next Season
Kevin Huerter

Iffy for Sunday Night
Caris LeVert

Questionable for Game 7
Duncan Robinson

Back on Injury Report Ahead of Game 7
Larry Nance Jr.

Likely Out Sunday Due to Illness
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Aaron Rodgers

Signs One-Year Deal With Steelers
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Isaac TeSlaa

Can Isaac TeSlaa Carve Out a Larger Role in Detroit Going Forward?
Troy Franklin

Facing Uphill Battle for Playing Time in Denver
Trevor Lawrence

Should Trevor Lawrence Be Valued as a Dynasty QB1?
Courtland Sutton

in Line for Reduced Role in Denver?
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Duncan Robinson

Nets 14 Points With Four Triples
Cade Cunningham

Contributes 21 Points in Game 6 Win
Jalen Duren

Bounces Back With Double-Double
Anthony Edwards

Finishes Season-Ending Loss With 24 Points
Victor Wembanyama

Tallies 19 Points in Friday's Win
De'Aaron Fox

Highly Effective in Blowout Win
Stephon Castle

Shines in Series-Clincher
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Jordan Westburg

to Have Season-Ending Elbow Surgery
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Tarik Skubal

Resumes Playing Catch, Ahead of Schedule?
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
Pavel Dorofeyev

Enjoys Second Consecutive Multi-Goal Game
Shea Theodore

Records Two Points in Game 6 Win
Mitchell Marner

Scores Special Goal in Series-Clincher
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Quinn Hughes

Finishes Postseason With 15 Points
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
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