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Top 10 NFL Defenses: Weeks 16,17 First Look and Rankings

Buffalo Bills Defense - Fantasy Football DST Rankings, Draft Sleepers

No. 1 Buffalo Bills (vs. New England Patriots, New York Jets)

If the Bills are somehow still available on waivers, make sure to pick them up immediately. This unit will have an extremely favorable matchup in Week 16 against the Patriots and could be used again in Week 17 against the Jets. Buffalo ranks tied for third in takeaways (24) and has forced a turnover in 12 of 13 games this season.

For Week 16, the Bills defense will be a top-5 play at home. In Week 17, Buffalo will have some potential against a Jets offense that has certainly had its struggles throughout the year. Aaron Rodgers has been sacked at least three times in three of the past four games.

Los Angeles Chargers Defense D/ST Streamers, Rankings, Waiver Wire - Khalil Mack Fantasy Football IDP

No. 2 Los Angeles Chargers (vs. Denver Broncos, New England Patriots)

The Chargers will be a top-3 play in the fantasy football championship against the Patriots, so make sure to pick them up ahead of Week 15. Los Angeles ranks fifth in sacks (39) this season, and this defense has totaled at least three sacks in five of the past seven games.

New England has given up 43 sacks (tied for the fourth-most) this season, and Maye has been sacked at least three times in four of the past five games. He has also thrown six interceptions across the last five contests. They are a top play in Week 17 even with a tougher matchup in Week 16 against the Denver Broncos.

No. 3 New Orleans Saints (vs. Green Bay Packers, Las Vegas Raiders)

The Saints defense won’t be a strong fantasy option in Week 16 against the Packers. However, this unit has a ton of potential against the Raiders in the fantasy football championship. New Orleans has totaled multiple sacks in four straight games, and Las Vegas has allowed 43 sacks this season.

While it remains to be seen if Desmond Ridder or Aidan O’Connell (knee) will start in this game, the Saints will have a high enough fantasy floor to be a top-7 play at home in Week 17. The Raiders also rank first in giveaways and 24th in pass-block win rate this season.

Green Bay Packers Defense - Rashan Gary, DST, D/ST, Rankings, Streamers

No. 4 Green Bay Packers (vs. New Orleans Saints, Minnesota Vikings)

Whether you have a first-round bye or just looking for a defense in advance, the Packers should be added in almost all formats right now. That’s because Green Bay will go up against the Saints in Week 16. With Derek Carr recovering from a fractured hand, there’s a strong chance that Jake Haener will draw another start under center for New Orleans.

This unit has a ton of potential in Week 16 against a Saints offense that will likely be missing Carr, Taysom Hill (knee), and Chris Olave (concussion). New Orleans also ranks 31st in pass-block win rate in 2024. In Week 17, they should be avoided facing a tough Minnesota offense.

Indianapolis Colts Defense - DST Rankings, Julian Blackmon, IDP Fantasy Football

No. 5 Indianapolis Colts (vs. Tennessee Titans, New York Giants)

The Colts are one of the few defenses that can be picked up and played in both Week 16 and Week 17. They’ll play the Titans in the second round of the fantasy football playoffs and the Giants in the championship. 

Opposing defenses are averaging 11.2 fantasy points against the Titans offense this season, and Will Levis has been sacked 24 times over the past five weeks. That’s great news for a Colts defense that has totaled at least three sacks in four of the past five games. After that great matchup in Week 16, the Colts can be used again in Week 17 against the Giants. New York will be starting either Drew Lock or Tommy DeVito in the fantasy football championship, and that offensive line has allowed 12 sacks over the past three games. 

No. 6 Seattle Seahawks (vs. Minnesota Vikings, Chicago Bears)

The Seahawks’ defense should be on everyone’s radar heading into the final weeks of the season. While this unit likely shouldn’t be started in Week 16 against the Vikings, it has a fantastic matchup against the Bears in the fantasy football championship.

Chicago has given up the most sacks (56) this season, and Caleb Williams has been taken down 33 times since Week 9. They have totaled multiple sacks in four straight weeks and have forced nine interceptions over the past seven games. 

No. 7 Tampa Bay Buccaneers (vs. Dallas Cowboys, Carolina Panthers)

In Week 16, the Buccaneers will face the Dallas Cowboys who have struggled to find consistency with Cooper Rush under center. Last weekend, they scored 30 points against the Panthers but the week before they scored only 20 and allowed three sacks with an interception against the Bengals. The Panthers have shown some upside at times but similar to Dallas have struggled to deliver on a consistent basis.

Over their past two games, the Buccaneers have allowed less than 20 points in each of them. Over this span they have tallied five sacks and two interceptions making them a viable low-end streaming option.

Titans Defense D/ST Streamers, Rankings, Waiver Wire - Harold Landry Fantasy Football IDP

No. 8 Tennessee Titans (vs. Indianapolis Colts, Jacksonville Jaguars)

Last weekend, Anthony Richardson and the Colts struggled against a tough Denver defense scoring only 13 points and allowed two sacks with two interceptions. The Jaguars offense took a step forward last weekend but remain a top streaming matchup given Mac Jones’ struggles serving as Trevor Lawrence’s replacement.

The Titans have allowed at least 30+ points in three of their past four contests. While this makes them a difficult option to trust, given their two positive matchups, they could be viewed as a last-resort option. They have tallied four interceptions in their past two games and could find similar success facing two inconsistent quarterbacks.

Jessie Bates Atlanta Falcons Defense - Fantasy Football DST, Defense Streamers, Waiver Wire IDP

No. 9 Atlanta Falcons (vs. New York Giants, Washington Commanders)

The Falcons have one of the best matchups in Week 16, with one of the most challenging in Week 17. This weekend, they will face the New York Giants who have scored just 25 combined points in their previous two games. During this span they have been sacked five times and thrown two interceptions. However, they should not be started in Week 17 facing a potent Washington offense.

The Falcons are coming off a strong defensive showing in Week 15 where they held the Raiders to just nine points. In this game they tallied a safety, four sacks, and two interceptions. They should have similar success against the Giants.

Trey Hendrickson Cincinnati Bengals Defense - Fantasy Football DST Streamers, Rankings, Pickups

Fool's Gold Streamer: Cincinnati Bengals (vs. Cleveland Browns, Denver Broncos)

In Jameis Winston‘s six starts this season, he has shown that he can still air it out in the passing game. That has led to the Browns scoring at least 24 points in three of those games. Even though last weekend he struggled, he could have a nice bounce-back performance especially given Cincinnati’s struggles in the secondary.

During the fantasy championships they face the Denver Broncos who have scored at least 29 points in each of their past four games and will likely be in store for another high-scoring affair facing the Bengals.

REAL-TIME FANTASY NEWS

Braelon Allen

Dynasty Stock Takes a Hit After Teammate's Extension
Josh Allen

Still the Top Dynasty QB in his Prime
Kyler Murray

Suddenly a Rising Dynasty Target in Minnesota
Logan Webb

on Track to Start Against Dodgers on Monday
Mike Matheson

Leads by Example in Game 2 Win
Jakub Dobes

Rebounds After Loss Yet Again for Montreal
Rachaad White

Undervalued in Dynasty Leagues Despite a Path to Upside
Alex Newhook

Sets Tone in Big Montreal Victory
Stephon Castle

Overcomes Shooting Struggles Friday
Jake Tonges

Should by Now Be Rostered by Every Kittle Dynasty Manager
Anthony Edwards

Carries Heavy Usage in Defeat
Chig Okonkwo

a Clear Breakout Candidate in Washington
Lukas Dostal

Gets Pulled in Game 3 Loss on Friday
Victor Wembanyama

Joins Historic Playoff Company
Mikal Bridges

Continues Postseason Surge with 23-Point Game
Aaron Jones Sr.

Still a Low-Cost, Short-Term Dynasty Target
Kelly Oubre Jr.

Keeps Scoring Role Alive
Romeo Doubs

' Buy Window Could Soon Be Wide Open
Joel Embiid

Held to 18 Points in 76ers Game 3 Loss
Brett Howden

Notches Sixth Goal of the Postseason
Jalen Brunson

Tallies 33 Points to Take 3-0 Series Lead
VEG

Mitch Marner Hat Trick Helps Vegas Take Series Lead
Pat Bryant

Working With Training Staff This Offseason
Jacoby Brissett

in Communication With Cardinals Despite Skipping Workouts
Daniel Jones

Could Take Part in 7-on-7 Drills at OTAs
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Sam Merrill

Iffy for Game 3 on Saturday
Anthony Edwards

Rejoins Starting Lineup Friday
Kevin Huerter

Likely to Remain Out Saturday
Jarred Vanderbilt

Considered Questionable for Saturday
Jalen Williams

Ruled Out for Game 3 Against Lakers
Ayo Dosunmu

Cleared to Play Friday
Anthony Edwards

Available Friday Night
Joel Embiid

is Returning for Game 3 on Friday
Brandon Ingram

Undergoes Heel Surgery
Josh Hart

is Available to Play in Game 3
OG Anunoby

is Downgraded to Out for Game 3 on Friday
Mitchell Robinson

is Returning for Game 3
Mats Zuccarello

Expected to Play Saturday
Joel Eriksson Ek

to Be a Game-Time Decision Saturday
Jonas Brodin

Still Out Saturday
Josh Manson

Could Return Saturday
Kaedan Korczak

Scratched for Game 3 Against Ducks
Radko Gudas

Likely to Remain Out Friday
Sam Carrick

Won't Play Friday
Isiah Pacheco

Can Isiah Pacheco Re-Establish His Dynasty Value in Detroit?
Rico Dowdle

Dynasty Ceiling Limited By Backfield Committee in Pittsburgh
Rashid Shaheed

a High-Risk, High-Reward Buy-Low Candidate for Dynasty Managers
Marcus Mariota

Is Marcus Mariota Worth Stashing as an Injury Replacement in Dynasty Leagues?
Jacoby Brissett

a Clear Sell-High Candidate for Dynasty Managers
Blake Snell

to Make Season Debut for Dodgers on Saturday
Najee Harris

Can Najee Harris Re-Establish Some Dynasty Value in 2026?
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Breece Hall

Jets Sign Breece Hall to Three-Year Extension Worth $45.75 Million
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

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Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
Denver Broncos

Broncos Sign GM George Paton to New Five-Year Deal
Brandon McManus

Packers Release Kicker Brandon McManus
New York Jets

Jets Talking to a "Number of Veteran Quarterbacks"
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
Austin Reaves

Scores 31 Points in Game 2 Defeat
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
Chet Holmgren

Anchors Thunder Past Lakers in Game 2
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
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Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
Dan Vladar

Looks to Return to Winning Ways Thursday
Connor Dewar

Penguins Re-Sign Connor Dewar for Two Years
Mikko Rantanen

Played Through Torn MCL Late in the Season
Rasmus Dahlin

Ready to Go Friday
Alexander Nikishin

Set to Return Thursday
Christian Dvorak

Available Thursday
Owen Tippett

Remains Out Thursday
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Mark Stone

Nets Late Power-Play Goal in Losing Effort
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Framber Valdez

Suspended Six Games
Tyler Glasnow

Exits Early on Wednesday With Back Pain
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Brandon Woodruff

has Fluid Drained From his Right Shoulder
Brandon Woodruff

to Resume Throwing on Saturday, Return Imminent?
Carlos Correa

to Have Season-Ending Ankle Surgery
Jacob Misiorowski

Listed as Friday's Probable Starter
Logan Webb

Dealing With Knee Discomfort
Carlos Correa

Expected to Miss Significant Time With Ankle Injury
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Emilio Pagán

Emilio Pagan Headed for Injured List With Hamstring Injury
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Tim Elliott

Drops Decision At UFC Perth
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
William Byron

Might have the Speed to Compete for the Win at Texas
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
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