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Top 10 NFL Defenses: Weeks 16,17 First Look and Rankings

Buffalo Bills Defense - Fantasy Football DST Rankings, Draft Sleepers

No. 1 Buffalo Bills (vs. New England Patriots, New York Jets)

If the Bills are somehow still available on waivers, make sure to pick them up immediately. This unit will have an extremely favorable matchup in Week 16 against the Patriots and could be used again in Week 17 against the Jets. Buffalo ranks tied for third in takeaways (24) and has forced a turnover in 12 of 13 games this season.

For Week 16, the Bills defense will be a top-5 play at home. In Week 17, Buffalo will have some potential against a Jets offense that has certainly had its struggles throughout the year. Aaron Rodgers has been sacked at least three times in three of the past four games.

Los Angeles Chargers Defense D/ST Streamers, Rankings, Waiver Wire - Khalil Mack Fantasy Football IDP

No. 2 Los Angeles Chargers (vs. Denver Broncos, New England Patriots)

The Chargers will be a top-3 play in the fantasy football championship against the Patriots, so make sure to pick them up ahead of Week 15. Los Angeles ranks fifth in sacks (39) this season, and this defense has totaled at least three sacks in five of the past seven games.

New England has given up 43 sacks (tied for the fourth-most) this season, and Maye has been sacked at least three times in four of the past five games. He has also thrown six interceptions across the last five contests. They are a top play in Week 17 even with a tougher matchup in Week 16 against the Denver Broncos.

No. 3 New Orleans Saints (vs. Green Bay Packers, Las Vegas Raiders)

The Saints defense won’t be a strong fantasy option in Week 16 against the Packers. However, this unit has a ton of potential against the Raiders in the fantasy football championship. New Orleans has totaled multiple sacks in four straight games, and Las Vegas has allowed 43 sacks this season.

While it remains to be seen if Desmond Ridder or Aidan O’Connell (knee) will start in this game, the Saints will have a high enough fantasy floor to be a top-7 play at home in Week 17. The Raiders also rank first in giveaways and 24th in pass-block win rate this season.

Green Bay Packers Defense - Rashan Gary, DST, D/ST, Rankings, Streamers

No. 4 Green Bay Packers (vs. New Orleans Saints, Minnesota Vikings)

Whether you have a first-round bye or just looking for a defense in advance, the Packers should be added in almost all formats right now. That’s because Green Bay will go up against the Saints in Week 16. With Derek Carr recovering from a fractured hand, there’s a strong chance that Jake Haener will draw another start under center for New Orleans.

This unit has a ton of potential in Week 16 against a Saints offense that will likely be missing Carr, Taysom Hill (knee), and Chris Olave (concussion). New Orleans also ranks 31st in pass-block win rate in 2024. In Week 17, they should be avoided facing a tough Minnesota offense.

Indianapolis Colts Defense - DST Rankings, Julian Blackmon, IDP Fantasy Football

No. 5 Indianapolis Colts (vs. Tennessee Titans, New York Giants)

The Colts are one of the few defenses that can be picked up and played in both Week 16 and Week 17. They’ll play the Titans in the second round of the fantasy football playoffs and the Giants in the championship. 

Opposing defenses are averaging 11.2 fantasy points against the Titans offense this season, and Will Levis has been sacked 24 times over the past five weeks. That’s great news for a Colts defense that has totaled at least three sacks in four of the past five games. After that great matchup in Week 16, the Colts can be used again in Week 17 against the Giants. New York will be starting either Drew Lock or Tommy DeVito in the fantasy football championship, and that offensive line has allowed 12 sacks over the past three games. 

No. 6 Seattle Seahawks (vs. Minnesota Vikings, Chicago Bears)

The Seahawks’ defense should be on everyone’s radar heading into the final weeks of the season. While this unit likely shouldn’t be started in Week 16 against the Vikings, it has a fantastic matchup against the Bears in the fantasy football championship.

Chicago has given up the most sacks (56) this season, and Caleb Williams has been taken down 33 times since Week 9. They have totaled multiple sacks in four straight weeks and have forced nine interceptions over the past seven games. 

No. 7 Tampa Bay Buccaneers (vs. Dallas Cowboys, Carolina Panthers)

In Week 16, the Buccaneers will face the Dallas Cowboys who have struggled to find consistency with Cooper Rush under center. Last weekend, they scored 30 points against the Panthers but the week before they scored only 20 and allowed three sacks with an interception against the Bengals. The Panthers have shown some upside at times but similar to Dallas have struggled to deliver on a consistent basis.

Over their past two games, the Buccaneers have allowed less than 20 points in each of them. Over this span they have tallied five sacks and two interceptions making them a viable low-end streaming option.

Titans Defense D/ST Streamers, Rankings, Waiver Wire - Harold Landry Fantasy Football IDP

No. 8 Tennessee Titans (vs. Indianapolis Colts, Jacksonville Jaguars)

Last weekend, Anthony Richardson and the Colts struggled against a tough Denver defense scoring only 13 points and allowed two sacks with two interceptions. The Jaguars offense took a step forward last weekend but remain a top streaming matchup given Mac Jones’ struggles serving as Trevor Lawrence’s replacement.

The Titans have allowed at least 30+ points in three of their past four contests. While this makes them a difficult option to trust, given their two positive matchups, they could be viewed as a last-resort option. They have tallied four interceptions in their past two games and could find similar success facing two inconsistent quarterbacks.

Jessie Bates Atlanta Falcons Defense - Fantasy Football DST, Defense Streamers, Waiver Wire IDP

No. 9 Atlanta Falcons (vs. New York Giants, Washington Commanders)

The Falcons have one of the best matchups in Week 16, with one of the most challenging in Week 17. This weekend, they will face the New York Giants who have scored just 25 combined points in their previous two games. During this span they have been sacked five times and thrown two interceptions. However, they should not be started in Week 17 facing a potent Washington offense.

The Falcons are coming off a strong defensive showing in Week 15 where they held the Raiders to just nine points. In this game they tallied a safety, four sacks, and two interceptions. They should have similar success against the Giants.

Trey Hendrickson Cincinnati Bengals Defense - Fantasy Football DST Streamers, Rankings, Pickups

Fool's Gold Streamer: Cincinnati Bengals (vs. Cleveland Browns, Denver Broncos)

In Jameis Winston‘s six starts this season, he has shown that he can still air it out in the passing game. That has led to the Browns scoring at least 24 points in three of those games. Even though last weekend he struggled, he could have a nice bounce-back performance especially given Cincinnati’s struggles in the secondary.

During the fantasy championships they face the Denver Broncos who have scored at least 29 points in each of their past four games and will likely be in store for another high-scoring affair facing the Bengals.

REAL-TIME FANTASY NEWS

Chris Brazzell II

a Year 1 Breakout Candidate in Carolina?
Ja'Kobi Lane

a Great Fit for Ravens, Potential Steal in Rookie Drafts
Josh Jacobs

Back at Practice on Tuesday
Max Klare

Crowded Tight End Room Impacting Max Klare's Dynasty Stock?
Romeo Doubs

Still a Solid Dynasty Option in New England?
CFB

SEC Coach Calls Buster Faulkner a "Home-Run Hire"
CFB

Auburn a Sleeper in the SEC Under Alex Golesh?
CFB

Noah Fifita Primed for Strong 2026 Campaign
CFB

Oregon Assistant Coach Charged with DUII, Reckless Driving
Makai Lemon

Set for Major Role in Debut Season?
CFB

Tight End Nick Pollack Commits to Clemson
Drake Maye

Does Latest Addition Put Drake Maye Among the Upper Echelon of Fantasy Elite?
Jalen Hurts

Could Face Regression After Loss of Top Pass Catcher
DeVonta Smith

Poised for WR1 Role in the Aftermath of Trade?
Daniel Jones

Participating in 7-on-7s
Akshay Bhatia

Needs the Driver to be True in Ohio
Aaron Rai

Primed to take on the Memorial Tournament
J.J. Spaun

Rebounded at Charles Schwab Challenge
Xander Schauffele

One to Watch This Week in Ohio
Hideki Matsuyama

Putter Could be Vital at the Memorial
Nicolai Hojgaard

Rust Concerns at Muirfield Village
Ryan Gerard

Surfaces After Long Cold Stretch with Top 10 Result
Wyndham Clark

May Struggle at the Memorial Tournament
Elly De La Cruz

to Miss 2-4 Weeks of Action
Chase Burns

is Scratched Due to Illness
A.J. Brown

Traded to Patriots in Blockbuster Deal
Deiveson Figueiredo

Suffers Second-Round Submission Loss
Song Yadong

Gets Second-Round Submission Win
Russell Wilson

Taking a Job with CBS for 2026 Season
JuJu Smith-Schuster

Giants Adding JuJu Smith-Schuster on a One-Year Deal
Zhang Mingyang

Suffers Back-To-Back Losses
Alonzo Menifield

Gets Back In The Win Column
Braxton Berrios

New York Giants Agree to One-Year Deal with Braxton Berrios
Odell Beckham Jr.

Signing with Giants
Tallison Teixeira

Suffers First-Round Knockout Loss
Myles Garrett

and Jared Verse Swap Teams in Blockbuster Deal
Sergei Pavlovich

Scores First-Round Knockout Win
Cameron Smotherman

Suffers Third Loss In A Row
Edwin Arroyo

Reds Promote Top Infield Prospect Edwin Arroyo, Viewed as Priority Pick Up Ahead of MLB Debut
Kai Asakura

Earns His First UFC Win
Elly De La Cruz

Placed on IL with Right Hamstring Tightness
Mason Taylor

Dynasty Value Takes a Hit for Now
Denny Hamlin

Earns the first Nashville Cup Series Victory of his Career on Sunday
Zachariah Branch

a Steal in the Second Round of Rookie Drafts?
Christopher Bell

Finishes as the Runner-Up at Nashville
Chase Briscoe

Earns First Career Podium Finish at Nashville
Ryan Blaney

Scores A Solid Top-10 Finish at Nashville
Eli Stowers

Worth Targeting Now Before Eventual Breakout?
Kyle Larson

Top-10 Streak at Nashville Ends after Late Flat Tire Spin
Germie Bernard

Expected to Require Some Patience in Dynasty Leagues
Denzel Boston

a First-Round Target in Dynasty Rookie Drafts
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Chet Holmgren

Fails to Step Up in the Season Finale
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Kyrie Irving

Reports He's Nearing Full Strength in ACL Recovery
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Mitchell Robinson

Plans to Play in Game 1 After Finger Surgery
Ajay Mitchell

Ruled Out for Game 7
Jalen Williams

Unavailable in Decisive Game 7
NBA

Magic Finalizing Hire of Sean Sweeney as Head Coach
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
Jalen Williams

Limited in Game 6 Return
Jared McCain

Provides Bench Spark in Game 6 Loss
Shai Gilgeous-Alexander

Posts Lowest-Scoring Night of His MVP Season
De'Aaron Fox

Struggles From the Field Thursday
MLB

MLB Proposes Hard Salary Cap as Part of Next CBA
Kenley Jansen

Tigers Place Kenley Jansen on Injured List With Pelvic Inflammation
Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
CAR

Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
RANKINGS
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