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QB vs Pass Rush Matchups To Watch - Week 10

Week 10 is in full swing, and we have to find our quarterbacks. We've had some lock-it-in options this year, but we've also had some players that have fallen short. In a week where we have a lot of quality defensive lines with decent matchups, good options are more difficult to find.

In addition to the guys discussed here, there are others with good or bad matchups, but we're trying to focus on ones that maybe you have to think extra about. You may even still start some of the bad matchup guys but as long as you're thinking about it, that's where we come in.

There are six teams on byes this week which makes finding a starting quarterback even more difficult. While a few teams, such as the Washington Redskins, don't inspire quarterback confidence, the New England Patriots, Houston Texans, and Philadelphia Eagles being off means you're likely missing a starter.

Be sure to check all of our fantasy football rankings for 2025:

 

Look Away Before It Gets Ugly

Sam Darnold vs New York Giants

New York Jets quarterback Sam Darnold just cannot buy a break. His offensive line has been decimated by injuries, and star running back Le'Veon Bell is now dealing with a knee injury. In Week 10, he doesn't play the NFL's best defense, but he'll likely be adding to his team's NFL-worst total of 37 sacks allowed. In just five games played, he's been sacked 18 times, including an eight-sack massacre at the hands of the Jacksonville Jaguars two weeks ago.

The New York Giants are "heading" to the Meadowlands this weekend, and their defensive line is looking to get after Darnold early. They've racked up 22 sacks thus far, which is tied for 10th in the NFL, and they're getting it done without elite production coming from any one player. EDGE rusher Markus Golden leads the team with 5.5 sacks while no one else has more than 2.5. Against a Jets team that will be without multiple starting offensive linemen for this week, this Giants Defense can harass Darnold.

Josh Allen @ Cleveland Browns

The Cleveland Browns entered the year with a ton of hype and praise. They had added talented players all over their offense, and it was their time to break out. That hasn't happened for several reasons, but the defense, specifically the pass rush, has been able to keep them in games. Behind defensive end Myles Garrett's 10 sacks, they've been able to harass quarterbacks week in and week out. If Cleveland is going to win this game, the pass rush has to get home and bother the opposing quarterback.

Buffalo Bills quarterback Josh Allen is mobile, athletic, and capable of making great plays. The only problem is that he's also shown a lack of awareness in the pocket that has resulted in him taking far too many sacks. He's been sacked 49 times in just 20 career games. Luckily for him, he'll have his full complement of offensive linemen, but this is one of the best group of pass rushers he's faced this season. On the road against a desperate team, this could be a rough week for him.

Kyle Allen @ Green Bay Packers

Carolina Panthers quarterback Kyle Allen took over for quarterback Cam Newton after Week 2. Outside of a drubbing at the hand of the San Francisco 49ers, he's been more than capable as he's 5-1 on the season. On Sunday, he gets a Green Bay Packers Defense that has been susceptible as of late, but a few factors are working against him. He's on the road in Lambeau Field where there is snow on the ground, and he's still without starting tackle Greg Little (concussion). Carolina has also given up 26 sacks on the year.

The Green Bay defense has had some trouble as of late, but they've been consistently getting after the quarterback this season. They're tied for 10th in the NFL with 22 sacks and in the games they've won handily this season, they have generated turnovers. Allen has thrown four picks in six games, and he had six fumbles in his first three games. If the Packers can generate pressure, which they should be able to, they can force Allen into a bad decision or two.

 

That's More Like It

Brian Hoyer vs Miami Dolphins

Indianapolis Colts backup quarterback Brian Hoyer ends up in this spot due to quarterback Jacoby Brissett (knee) being unable to play. The Colts offensive line has been one of the best in football over the last two seasons, and they're a top-10 unit on the year right now despite a couple of down weeks. They've allowed just 16 sacks on the year, and nine of those have come in the last two weeks. They have far more good than bad tape.

In Week 10, they get the Miami Dolphins at home. The Dolphins Defense has just 12 sacks on the year, and they're still not getting after the passer at a consistent rate with an adjusted sack rate of just 5.0 percent. This will be a home game for the Colts and while the Dolphins will be riding high after their first win of the season, most of that has come from the offense under quarterback Ryan FitzpatrickHoyer has a good matchup this week.

Jimmy Garoppolo vs Seattle Seahawks

The San Francisco 49ers are undefeated but they get their toughest test of the season on Monday night against the Seattle Seahawks. However, that test won't be on the defensive side of the ball. Seattle is allowing over 25 points per game, and they're the fifth-worst team in the league in passing yards per game allowed in large part because of their lack of a pass rush. They have just 15 sacks, which is tied for the sixth-worst mark in the NFL.

49ers quarterback Jimmy Garoppolo hasn't been lighting up the stat sheet this year, but this is as good of a matchup as he's going to get. He's at home with a decent weather forecast against a division rival. The 49ers have an elite defense, but the Seahawks have an elite offense. Quarterback Russell Wilson will find ways to put points on the board, and Jimmy G will have to keep up. Against a bad defense in a game where he will likely have to throw a fair bit, he's got a good matchup.

Mitch Trubisky vs Detroit Lions

Before you come after me about Chicago Bears quarterback Mitchell Trubisky, hear me out. He's a mobile passer playing at home against a Detroit Lions Defense that has been rather ineffective at rushing the passer. Trubisky, in the one game he played against Detroit last season, threw for over 300 yards and three touchdowns. His offensive line is around the middle of the pack at keeping him upright, but this comes down to Trubisky still having the tools to be successful.

The Lions defense has struggled to get after the quarterback, and, outside of the Week 2 matchup with the Los Angeles Chargers, all of their opponents have scored 23 or more points. They're tied for the fifth-worst mark in the NFL with 14 sacks on the year and they're playing on the road. In a lot of league styles, you're not starting Trubisky, but, if he's your third quarterback in a two-QB league where one of your guys is on a bye, you could have a worse option this week.

More Weekly Lineup Prep




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REAL-TIME FANTASY NEWS

D'Andre Swift

Active for Week 10 Against Giants
Harold Fannin Jr.

Active Against Jets
Aaron Jones Sr.

Active for Week 10 Against Ravens
Tetairoa McMillan

Suiting Up Against Saints in Week 10
Garrett Wilson

Officially Active Against Browns
Alvin Kamara

Active for Week 10 Against Panthers
Daniel Jones

Colts Plan to Offer Daniel Jones a Long-Term Extension
Micah Parsons

Prohibited From Being Traded Back to NFC East?
Cooper Kupp

Still Up in the Air for Week 10
Jayden Daniels

Will be Re-Evaluated During Bye Week
Scott Laughton

to Miss Sunday's Action
Ryan McDonagh

Exits With Injury Saturday
William Karlsson

Out Day-to-Day
Warren Foegele

Ready to Rejoin Kings Lineup Sunday
Jalen Chatfield

Out Indefinitely
Dougie Hamilton

to Miss at Least One Week
Harold Fannin Jr.

Likely Good to Go Against the Jets
Cedric Tillman

Anticipated to Play on Sunday
Tetairoa McMillan

Likely Playing on Sunday
D'Andre Swift

Anticipated to Play Against the Giants
Garrett Wilson

Expected to Suit Up in Week 10
Luke Kennard

Out On Saturday Night Against Lakers, Will Miss Second Straight Game
Maxi Kleber

Will Make Season Debut Saturday Night Against Hawks
Dean Wade

Questionable For Saturday Night Against Bulls
Larry Nance Jr.

Listed As Questionable For Saturday Night Against Bulls
Jared McCain

Available For Saturday Night Against Raptors
Ryker Evans

Comes Off Injured Reserve
Bilal Coulibaly

Officially Out For Saturday Night Against Mavericks
Joey Daccord

Kraken Place Joey Daccord on Injured Reserve
Jordan Kyrou

Rejoins Blues Lineup Saturday
Anthony Cirelli

Won't Play on Saturday
Casey Mittelstadt

Misses Meeting With Maple Leafs
Charlie McAvoy

Sits Out Saturday's Game
Sean Monahan

a Game-Time Decision Saturday
Tetairoa McMillan

Trending Towards Playing in Week 10
Jamal Murray

Listed As Questionable For Saturday Night Against Pacers
Aaron Gordon

Questionable For Saturday Night Against Pacers
Norman Powell

Listed As Probable For Saturday Night Against Blazers
Jaime Jaquez Jr.

Listed Questionable For Saturday Night Against Blazers
Bam Adebayo

Ruled Out For Second Straight Game
A.J. Brown

Off Final Injury Report, Set To Play Monday Versus Packers
Jalen Johnson

Questionable For Saturday Night Against Lakers
Saquon Barkley

Cleared From Final Injury Report, Good To Go For Monday
Nickeil Alexander-Walker

Listed As Questionable For Saturday Against Lakers
Ayo Dosunmu

Listed As Probable For Saturday Night Against Cleveland
Jakob Poeltl

Ruled Out For Saturday's Matchup Against Sixers
Justin Fields

Set to Start in Week 10 Against Browns
Aaron Jones Sr.

Expected to Play Sunday Against Ravens
Kristaps Porzingis

Ruled Out Versus the Lakers
Darius Garland

Resting on Saturday Night
Kyshawn George

in Danger of Missing Another Game on Saturday
Dereck Lively II

Not Expected to Face the Wizards
Daniel Gafford

on the Injury Report for Saturday Night
Anthony Davis

Questionable to Play Versus the Wizards
Brock Purdy

Could Return in Week 11
Artemi Panarin

Ends Dry Spell With Three-Point Outing
Marcus Johansson

Extends Point Streak to Eight Games
Spencer Knight

Posts First Shutout of the Season
Matt Duchene

to Remain Out Saturday
Zayne Parekh

Expected to "Miss a Little Bit of Time"
Frank Nazar

Day-to-Day Following Friday's Early Exit
Aaron Judge

Headlines AL Silver Slugger Award Winners
William Eklund

Moved to Injured Reserve
Gustav Nyquist

Expected to Remain Out Friday
Shohei Ohtani

Headlines List of NL Silver Slugger Winners
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Munetaka Murakami Officially Being Posted on Friday
Randy Brown

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Gabriel Bonfim

Looks To Extend His Win Streak
Joseph Morales

A Favorite At UFC Vegas 111
Matt Schnell

Set For UFC Vegas 111 Co-Main Event
Uros Medic

Aims To Win Back-To-Back Fights
Muslim Salikhov

Looks For His Fourth Consecutive Win
Chris Padilla

Looks To Remain Unbeaten In The UFC
Ismael Bonfim

Looks To Get Back In The Win Column
Marco Tulio

Looks To Remain Undefeated In The UFC
Christian Leroy Duncan

Set To Open Up UFC Vegas 111 Main Card
Kyle Tucker

Headlines List of 13 Players to Receive Qualifying Offers
Pete Fairbanks

Becomes a Free Agent
CFB

Luke Fickell Will Return as Wisconsin's Head Coach in 2026
Bo Bichette

Blue Jays Extend Qualifying Offer to Bo Bichette
Craig Stammen

Named Padres New Manager
Jorge Polanco

Declines his 2026 Option to Become a Free Agent
Chris Sale

Braves Picking Up Chris Sale's 2026 Option
Michael Thorbjornsen

Poised to Continue Hot Play in Mexico
Davis Riley

Struggling to Find Form Ahead of World Wide Technology Championship
Taylor Montgomery

Leaning on Putter at World Wide Technology Championship
Stephan Jaeger

Offers Strong Value at World Wide Technology Championship
Ben Griffin

Looks to Stay Hot at El Cardonal
Nick Dunlap

Looking to Find His Game at El Cardonal
Wyndham Clark

Searching for Consistency at El Cardonal
Michael Brennan

Aims to Extend Fairytale Start at El Cardonal
Shane Bieber

Staying in Toronto for 2026
Salvador Perez

Agrees to Two-Year Extension With Royals
Trevor Story

Opts in for Remaining Two Years on his Contract
Yu Darvish

to Miss All of 2026 Following Flexor-Tendon Surgery
Shota Imanaga

Becomes a Free Agent
Luis Robert Jr.

White Sox Pick Up 2026 Option on Luis Robert Jr.
CFB

LJ Martin Expected to Play in Top-10 Matchup Against Texas Tech
PGA

LIV Golf Expanding To 72-Hole Format In 2026
Atlanta Braves

Braves Hire Walt Weiss as Their Next Manager
Kris Bubic

Cleared to Begin a Throwing Program
Brandon Woodruff

Declines Mutual Option for 2026
Freddy Peralta

Brewers Exercise 2026 Option on Freddy Peralta
Lucas Giolito

Declines his 2026 Player Option
J.J. Spaun

Finishes Sixth at Procore Championship
PGA

Matti Schmid Finishes Tied for 46th at Baycurrent Classic
Keith Mitchell

Finishes Tied for 10th at Baycurrent Classic
Si Woo Kim

Finishes Tied for 21st at Genesis Championship
Mackenzie Hughes

Misses The Cut at Sanderson Farms Championship
Max Greyserman

Finishes Second at Baycurrent Classic
Austin Eckroat

Finishes Tied for 56th at Baycurrent Classic
Luke Clanton

Finishes Tied for 56th at Bank of Utah Championship
Pete Alonso

Officially Opts Out of his Contract With Mets
Kyle Larson

Wins His Second NASCAR Cup Series Championship at Phoenix
Ryan Blaney

Concludes the 2025 Season with A Win at Phoenix
William Byron

Strong Championship Effort Ends With Late-Race Flat-Tire Crash

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