November 18, 2025
Arizona Cardinals running back
Emari Demercado suffered a high ankle sprain in Sunday's 41-22 loss to the San Francisco 49ers and is considered unlikely to play in Week 12 against the Jacksonville Jaguars, per Adam Schefter of ESPN. Demercado left the game in the second quarter after recording five carries for eight yards and two catches (three targets) for 12 tards. The injury comes at an unfortunate time for the 26-year-old as he was beginning to establish himself as the preferred option in Arizona's backfield, but he will now be sidelined for at least one week and possibly longer as ankle injuries tend to linger.
Bam Knight handled most of the backfield duties in his absence and would be expected to take on an even larger role if
Trey Benson (knee) is still unable to return in Week 12.
--Kyle McCarthySource: Adam Schefter
November 18, 2025
Arizona Cardinals quarterback
Jacoby Brissett completed an NFL record 47 passes in their 41-22 blowout loss to the San Francisco 49ers in Week 11. Brissett's 452 passing yards trail only
Joe Flacco's 470-yard performance in Week 9 for the most passing yards in a game this season. His passing volume has been among the highest in the league since taking over as the starter in Week 11. The 32-year-old signal caller has 212 pass attempts in that span, behind only Flacco, and is the QB4 in points per game (22.5). The Cardinals have often found themselves in negative game scripts, which has led to Brissett slinging it at a high rate. For fantasy managers looking for a viable quarterback with the slew of injuries at the position this year, Brissett is one of the better adds off the waiver wire this week and is only rostered in 23.6% of ESPN leagues.
--Kyle McCarthySource: Pro Football Reference
November 17, 2025
Arizona Cardinals running back
Bam Knight saw a scaled back role in the rushing game during Sunday's game against the San Francisco 49ers. Heading into this game, Knight had seen nine carries or more in each of his last four games. However, Knight carried the ball only five times for 24 yards and scored a touchdown in the loss. He also hauled in all four of his targets through the air for 21 additional yards. The fact the game was a blowout could've contributed to the lack of carries for Knight. He figures to have a bigger role during next week's matchup against the Jacksonville Jaguars. Fantasy managers should be able to plug in Knight as a low-end flex option
--Andy WebbSource: Pro Football Reference
November 17, 2025
Arizona Cardinals wide receiver
Greg Dortch has been a non-factor basically all season until making some noise during Sunday's game. Dortch was asked to step up into a larger role with
Marvin Harrison Jr. (appendix) sidelined this weekend. The 27-year-old delivered as he hauled in all six of his targets for 66 yards and a touchdown in the loss to the San Francisco 49ers. Dortch played a season-high 66 percent of the offensive snaps during this contest. He could be worth snagging off the waiver wire for Week 12, assuming Harrison misses another game.
--Andy WebbSource: Pro Football Reference
November 17, 2025
Arizona Cardinals running back
Trey Benson (knee) has been on Injured Reserve since Week 4 due to a knee injury. However, Cardinals head coach Jonathan Gannon indicated leading into Week 11 that Benson is a candidate to have his activation window opened in the near future. That could mean Benson has a chance to return for Arizona's Week 12 matchup against the Jacksonville Jaguars, although that's far from a guarantee at this point. With Cardinals running back
James Conner (ankle) out for the season, Benson profiles as the team's RB1 upon his return. In leagues where he is available, Benson may be worth targeting on the waiver wire for the stretch run of the fantasy season. If he remains out in Week 12, Arizona will likely continue splitting backfield work between
Bam Knight,
Emari Demercado, and
Michael Carter.
--Will BradySource: RotoBaller
November 17, 2025
Arizona Cardinals wide receiver
Michael Wilson had himself a career day on Sunday, as he set new career-best lines with 15 receptions and 185 receiving yards. The third-year receiver out of Stanford was thrust into duties on Sunday as Marvin Harrison (Appendicitis) and
Zay Jones (Achilles) both missed the game. The Cardinals were down early in this contest again, which set up perfectly for Wilson,
Jacoby Brissett, and
Trey McBride fantasy owners. Brissett threw for 452 yards, and McBride had 115 receiving yards and a touchdown to go along with Wilson's career day. If Harrison continues to miss time and Wilson is thrust into WR1 duties, he is borderline a must-start option in an offense that is racking up a ton of yards over the last three weeks. That being said, the Cardinals face the Jaguars in Week 12, who are stiffer competition than what the Cardinals had in Week 11. Regardless, Wilson is a must-add off the waiver wire right now, and should be comfortably in the WR3 conversation should Harrison miss additional time.
--Nicho RoesslerSource: RotoBaller
November 16, 2025
Arizona Cardinals quarterback
Jacoby Brissett completed 47 of his 57 pass attempts for 452 passing yards, two touchdowns, and two interceptions during Sunday's Week 11 loss against the San Francisco 49ers. Brissett's 47 completions broke the NFL's all-time single-game record, surpassing
Jared Goff and Drew Bledsoe, who both once had 45 completions. The two turnovers are a blemish on his stat line, but the veteran quarterback still drastically exceeded expectations in fantasy football, even without
Marvin Harrison Jr. (appendix) at his disposal. He has 11 total touchdowns in five games since taking over for
Kyler Murray (foot), and during that span, he ranks as the overall QB4 in fantasy points per game. He has emerged as a must-start quarterback for Week 12 against the Jacksonville Jaguars.
--Andersen PickardSource: RotoBaller
November 16, 2025
Arizona Cardinals tight end
Trey McBride caught 10 of his 11 targets for 115 yards and one touchdown during Sunday's Week 11 loss against the San Francisco 49ers. McBride was already the top weapon in Arizona's passing attack, but he took on an even larger role this week with
Marvin Harrison Jr. (appendix) sidelined. The tight end benefited from
Jacoby Brissett completing 47 passes, which is a new NFL all-time single-game record. McBride now has five consecutive games with a touchdown, scoring six different times in that span. He'll remain a must-start, high-end TE1 even after Harrison returns to action. The Cardinals will host the Jacksonville Jaguars in Week 12.
--Andersen PickardSource: RotoBaller
November 16, 2025
Arizona Cardinals wide receiver
Michael Wilson caught 15 of his 18 targets for 185 yards during Sunday's Week 11 loss to the San Francisco 49ers. We knew Wilson was going to take on an expanded role with
Marvin Harrison Jr. (appendix) sidelined, but nobody could have predicted that he would be this involved and productive against the Niners. He benefited from
Jacoby Brissett setting a new record for most completions (47) in a single game in NFL history. It's unlikely that Brissett throws the ball as much next week, and it's also too early to tell whether Harrison will miss additional time. Nevertheless, Wilson's big game will keep him in the WR3/flex tier with WR2 upside for Week 12 against the Jacksonville Jaguars.
--Andersen PickardSource: RotoBaller
November 16, 2025
Arizona Cardinals running back
Emari Demercado (ankle) exited during the second quarter of Sunday's Week 11 contest against the San Francisco 49ers. He is officially listed as questionable to return. At the time of his departure, he had eight rushing yards on five carries, plus two catches for an additional 12 receiving yards. Demercado had been sharing reps as part of the Cardinals' backfield committee, so
Bam Knight should take over as the primary running back for the duration of his absence.
Michael Carter also figures to earn some touches.
--Andersen PickardSource: Arizona Cardinals
November 16, 2025
Arizona Cardinals running back
Bam Knight (ankle) is officially active for his team's Week 11 matchup against the San Francisco 49ers. Knight entered Sunday with a questionable injury designation after being limited in practice by an ankle injury. With running back
Trey Benson (knee) still out, Knight and
Emari Demercado should be expected to handle the majority of Arizona's backfield work against San Francisco. Veteran back
Michael Carter could be a factor as well. Knight profiles as a low-end flex option for fantasy managers in Week 11.
--Will BradySource: Arizona Cardinals
November 16, 2025
Arizona Cardinals running back
Bam Knight (ankle) is currently listed as questionable ahead of Sunday's Week 11 matchup against the San Francisco 49ers. Despite that, Knight is expected to play this weekend, according to Adam Schefter. Knight is stuck in a committee with
Emari Demercado and
Michael Carter. Last week, Knight saw 10 carries for 28 yards in the loss to the Seattle Seahawks. He hasn't been successful on the ground lately, so consider him a low-end flex option for Week 11.
--Andy WebbSource: Adam Schefter
November 15, 2025
Arizona Cardinals wide receiver
Xavier Weaver is expected to see an expanded role during the upcoming Week 11 matchup against the San Francisco 49ers. Weaver has barely played this season, and sat out last week's game due to an ankle issue. He appears to be healthy now and ready to make an impact. Weaver could be asked to step up with
Marvin Harrison Jr. (appendix) ruled out for Sunday's game. He figures to serve as the third wideout behind
Michael Wilson and
Greg Dortch. Weaver hasn't done enough on the field to warrant starting this weekend.
--Andy WebbSource: Pro Football Reference
November 15, 2025
Arizona Cardinals tight end
Elijah Higgins has seen an increased role on offense over the last few weeks. Over the last two games, Higgins has hauled in five of his six targets for 49 yards. Despite that, he remains the backup to
Trey McBride, who is one of the best tight ends in the league. It's possible that Higgins does see a slightly larger workload with
Marvin Harrison Jr. (appendix) out in Week 11. Normally, Higgins has been playing about 40 percent of the offensive snaps. There's a chance that does increase, but probably not by too much. Higgins is a desperation deep league option for the Week 11 matchup against the San Francisco 49ers.
--Andy WebbSource: Pro Football Reference
November 15, 2025
Arizona Cardinals tight end
Trey McBride should continue to handle a heavy workload, especially after the team announced that
Marvin Harrison Jr. (appendix) is ruled out for Week 11 against the San Francisco 49ers. Harrison is a talented playmaker who is capable of making catches in coverage, which is similar to McBride's skill set. As a result, when
Jacoby Brissett needs a receiver to make a physical or contested catch, he'll likely trust McBride more than some of the other wide receivers, such as
Michael Wilson or
Greg Dortch. McBride is already the TE1 in PPR scoring this year, catching 61 passes for 603 yards and a career-high six touchdowns. He'll have a chance to build on his strong campaign this Sunday against the 49ers. He remains a must-start fantasy tight end, especially against a 49ers defense allowing the fifth-most fantasy points to tight ends in 2025.
--Andersen PickardSource: RotoBaller
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