November 19, 2025
Arizona Cardinals running back
Emari Demercado (ankle) has been ruled out for the Week 12 contest this Sunday against the visiting Jacksonville Jaguars, head coach Jonathan Gannon said. Demercado suffered a high-ankle sprain in Week 11 and will sit out this weekend. Given the nature of the 26-year-old's injury, there's a good chance he'll miss another game in Week 13 versus the Tampa Bay Buccaneers, too. Meanwhile,
Trey Benson (knee) is having his 21-day practice window opened this week, so he's nearing a return for the first time since injuring his knee in Week 4. When Demercado gets over his ankle injury, he just might be the No. 4 RB on Arizona's depth chart, so he's certainly not worth stashing in 12-team fantasy leagues. With Demercado out this week and Benson probably not ready to return yet,
Bam Knight could get one more week as the RB1, with
Michael Carter working on passing downs.
--Keith HernandezSource: Arizona Sports - Tyler Drake
November 19, 2025
Arizona Cardinals head coach Jonathan Gannon has ruled out wide receiver
Marvin Harrison Jr. (appendix) for the Week 12 game on Sunday against the visiting Jacksonville Jaguars, according to Tyler Drake of Arizona Sports. Harrison had an appendectomy last week and will miss his second straight game this weekend. It remains to be seen if the 23-year-old second-year wideout will be able to return in Week 13 against the Tampa Bay Buccaneers. It's been another disappointing season for the fourth overall pick, although he has improved since quarterback
Jacoby Brissett took over for the injured
Kyler Murray (foot). Through nine games in 2025, Harrison has a 34-525-4 line on 62 targets.
Michael Wilson, who had an incredible 15 catches for 185 yards last week with Harrison out, should once again be primed for a heavy target load in Week 12.
Greg Dortch should serve as the WR2 again for Arizona, too.
--Keith HernandezSource: Arizona Sports - Tyler Drake
November 19, 2025
The Arizona Cardinals are opening the practice window for running back
Trey Benson (knee) to return from Injured Reserve, according to Tyler Drake of AZ Sports. Benson has been on IR since Week 4 due to a knee injury. While this move does not guarantee that he will be active for Week 12 against the Jacksonville Jaguars, it's clearly a positive sign that Benson's return will come in the next few weeks. Across four games this season, the 23-year-old has recorded 224 scrimmage yards on 42 touches. With running back
James Conner (ankle) out for the season, Benson profiles as the clear RB1 in Arizona once fully healthy. If Benson remains sidelined for Week 12, the Cardinals will likely turn to a combination of
Bam Knight and
Michael Carter to handle backfield snaps against Jacksonville.
UPDATE: Benson was officially limited in Wednesday's practice.--Will BradySource: AZ Sports - Tyler Drake
November 19, 2025
Arizona Cardinals wide receiver
Michael Wilson had himself a career day in Week 11, as he set new career-best lines with 15 receptions and 185 receiving yards. The third-year receiver out of Stanford was asked to step up because Marvin Harrison (Appendicitis) and
Zay Jones (Achilles) both missed the game. ESPN's Adam Schefter reported on November 12 that Harrison Jr. underwent surgery for appendicitis and will be sidelined for "at least Week 11 and possibly longer," meaning Wilson may be the team's WR1 in Week 12 if Harrison can't go. The key here is to pay attention to Harrison's practice leading up to Sunday, as Wilson slides down the rankings quite a bit if Harrison returns. Additionally,
Trey McBride is the team's clear number one option. Another thing to note, Brissett will not be throwing the football 57 times and for 452 yards every week. The Cardinals got punched in the mouth early and were behind the whole game, leading to a gameflow script that forced them to throw the ball the entire game. If Harrison plays, Wilson profiles as a WR3 with limited upside. If Harrison is ruled out, Wilson profiles as a low-end WR2 against a stiff Jacksonville Jaguars defense, which ranks much better than the San Francisco 49ers defense, against whom the Cardinals played last week.
--Nicho RoesslerSource: RotoBaller
November 19, 2025
Arizona Cardinals running back
Trey Benson (knee) has been on Injured Reserve since Week 4 due to a knee injury. However, Cardinals head coach Jonathan Gannon indicated that Benson is a candidate to have his activation window opened in the near future. That could mean Benson has a chance to return for Arizona's Week 12 matchup against the Jacksonville Jaguars. However, that appears to be up in the air at this point, given that most of the updates we have received about Benson haven't been encouraging to fantasy managers who have been holding onto him in their IR spots. Benson was pressed into RB1 duties when veteran running back
James Conner (foot) was injured in Week 3 and ruled out for the season; however, Benson was immediately injured in Week 4, which was his first game with RB1 opportunities. Benson profiles as the team's top running back upon his return, considering the Cardinals spent a third-round (66th overall) draft pick on him. In leagues where he is available, Benson is a must-add and stash on your bench or waiver wire. If he remains out in Week 12, the Cardinals will likely continue splitting backfield work between
Bam Knight and
Michael Carter, with
Emari Demercado (ankle) likely out in Week 12.
--Nicho RoesslerSource: RotoBaller
November 18, 2025
Arizona Cardinals running back
Michael Carter recorded a season-high five receptions on seven targets in his team's 41-22 Week 11 loss to the San Francisco 49ers. With Cardinals running back
Emari Demercado (ankle) likely to miss the team's Week 12 matchup against the Jacksonville Jaguars, Carter could be in line for a sizable role for a second straight week. The 26-year-old is unlikely to factor much on early downs, as Carter has fallen behind Arizona back
Bam Knight in the pecking order for carries. However, Carter has recorded at least five targets in three out of six games played for the Cardinals this season. One wrinkle for Carter is the potential return of
Trey Benson (knee), who could be returning soon from the knee injury that has kept him on Injured Reserve since Week 4. However, if Benson and Demercado are out in Week 12, Carter could have some deep-league fantasy appeal.
--Will BradySource: RotoBaller
November 18, 2025
Arizona Cardinals running back
Emari Demercado suffered a high ankle sprain in Sunday's 41-22 loss to the San Francisco 49ers and is considered unlikely to play in Week 12 against the Jacksonville Jaguars, per Adam Schefter of ESPN. Demercado left the game in the second quarter after recording five carries for eight yards and two catches (three targets) for 12 tards. The injury comes at an unfortunate time for the 26-year-old as he was beginning to establish himself as the preferred option in Arizona's backfield, but he will now be sidelined for at least one week and possibly longer as ankle injuries tend to linger.
Bam Knight handled most of the backfield duties in his absence and would be expected to take on an even larger role if
Trey Benson (knee) is still unable to return in Week 12.
--Kyle McCarthySource: Adam Schefter
November 18, 2025
Arizona Cardinals quarterback
Jacoby Brissett completed an NFL record 47 passes in their 41-22 blowout loss to the San Francisco 49ers in Week 11. Brissett's 452 passing yards trail only
Joe Flacco's 470-yard performance in Week 9 for the most passing yards in a game this season. His passing volume has been among the highest in the league since taking over as the starter in Week 11. The 32-year-old signal caller has 212 pass attempts in that span, behind only Flacco, and is the QB4 in points per game (22.5). The Cardinals have often found themselves in negative game scripts, which has led to Brissett slinging it at a high rate. For fantasy managers looking for a viable quarterback with the slew of injuries at the position this year, Brissett is one of the better adds off the waiver wire this week and is only rostered in 23.6% of ESPN leagues.
--Kyle McCarthySource: Pro Football Reference
November 17, 2025
Arizona Cardinals running back
Bam Knight saw a scaled back role in the rushing game during Sunday's game against the San Francisco 49ers. Heading into this game, Knight had seen nine carries or more in each of his last four games. However, Knight carried the ball only five times for 24 yards and scored a touchdown in the loss. He also hauled in all four of his targets through the air for 21 additional yards. The fact the game was a blowout could've contributed to the lack of carries for Knight. He figures to have a bigger role during next week's matchup against the Jacksonville Jaguars. Fantasy managers should be able to plug in Knight as a low-end flex option
--Andy WebbSource: Pro Football Reference
November 17, 2025
Arizona Cardinals wide receiver
Greg Dortch has been a non-factor basically all season until making some noise during Sunday's game. Dortch was asked to step up into a larger role with
Marvin Harrison Jr. (appendix) sidelined this weekend. The 27-year-old delivered as he hauled in all six of his targets for 66 yards and a touchdown in the loss to the San Francisco 49ers. Dortch played a season-high 66 percent of the offensive snaps during this contest. He could be worth snagging off the waiver wire for Week 12, assuming Harrison misses another game.
--Andy WebbSource: Pro Football Reference
November 17, 2025
Arizona Cardinals running back
Trey Benson (knee) has been on Injured Reserve since Week 4 due to a knee injury. However, Cardinals head coach Jonathan Gannon indicated leading into Week 11 that Benson is a candidate to have his activation window opened in the near future. That could mean Benson has a chance to return for Arizona's Week 12 matchup against the Jacksonville Jaguars, although that's far from a guarantee at this point. With Cardinals running back
James Conner (ankle) out for the season, Benson profiles as the team's RB1 upon his return. In leagues where he is available, Benson may be worth targeting on the waiver wire for the stretch run of the fantasy season. If he remains out in Week 12, Arizona will likely continue splitting backfield work between
Bam Knight,
Emari Demercado, and
Michael Carter.
--Will BradySource: RotoBaller
November 17, 2025
Arizona Cardinals wide receiver
Michael Wilson had himself a career day on Sunday, as he set new career-best lines with 15 receptions and 185 receiving yards. The third-year receiver out of Stanford was thrust into duties on Sunday as Marvin Harrison (Appendicitis) and
Zay Jones (Achilles) both missed the game. The Cardinals were down early in this contest again, which set up perfectly for Wilson,
Jacoby Brissett, and
Trey McBride fantasy owners. Brissett threw for 452 yards, and McBride had 115 receiving yards and a touchdown to go along with Wilson's career day. If Harrison continues to miss time and Wilson is thrust into WR1 duties, he is borderline a must-start option in an offense that is racking up a ton of yards over the last three weeks. That being said, the Cardinals face the Jaguars in Week 12, who are stiffer competition than what the Cardinals had in Week 11. Regardless, Wilson is a must-add off the waiver wire right now, and should be comfortably in the WR3 conversation should Harrison miss additional time.
--Nicho RoesslerSource: RotoBaller
November 16, 2025
Arizona Cardinals quarterback
Jacoby Brissett completed 47 of his 57 pass attempts for 452 passing yards, two touchdowns, and two interceptions during Sunday's Week 11 loss against the San Francisco 49ers. Brissett's 47 completions broke the NFL's all-time single-game record, surpassing
Jared Goff and Drew Bledsoe, who both once had 45 completions. The two turnovers are a blemish on his stat line, but the veteran quarterback still drastically exceeded expectations in fantasy football, even without
Marvin Harrison Jr. (appendix) at his disposal. He has 11 total touchdowns in five games since taking over for
Kyler Murray (foot), and during that span, he ranks as the overall QB4 in fantasy points per game. He has emerged as a must-start quarterback for Week 12 against the Jacksonville Jaguars.
--Andersen PickardSource: RotoBaller
November 16, 2025
Arizona Cardinals tight end
Trey McBride caught 10 of his 11 targets for 115 yards and one touchdown during Sunday's Week 11 loss against the San Francisco 49ers. McBride was already the top weapon in Arizona's passing attack, but he took on an even larger role this week with
Marvin Harrison Jr. (appendix) sidelined. The tight end benefited from
Jacoby Brissett completing 47 passes, which is a new NFL all-time single-game record. McBride now has five consecutive games with a touchdown, scoring six different times in that span. He'll remain a must-start, high-end TE1 even after Harrison returns to action. The Cardinals will host the Jacksonville Jaguars in Week 12.
--Andersen PickardSource: RotoBaller
November 16, 2025
Arizona Cardinals wide receiver
Michael Wilson caught 15 of his 18 targets for 185 yards during Sunday's Week 11 loss to the San Francisco 49ers. We knew Wilson was going to take on an expanded role with
Marvin Harrison Jr. (appendix) sidelined, but nobody could have predicted that he would be this involved and productive against the Niners. He benefited from
Jacoby Brissett setting a new record for most completions (47) in a single game in NFL history. It's unlikely that Brissett throws the ball as much next week, and it's also too early to tell whether Harrison will miss additional time. Nevertheless, Wilson's big game will keep him in the WR3/flex tier with WR2 upside for Week 12 against the Jacksonville Jaguars.
--Andersen PickardSource: RotoBaller
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