November 23, 2025
Arizona Cardinals wide receiver
Michael Wilson has immediately become a legitimate contributor for the Cardinals and fantasy managers in the last two games with
Marvin Harrison Jr. out following an appendectomy. For the second straight week, Wilson had double-digit receptions (10) and over 100 yards (118) on a team-15 targets in the team's 27-24 overtime loss to the Jacksonville Jaguars on Sunday in Week 12. Last week, the 25-year-old caught 15 of his 18 targets for 185 yards. Quarterback
Jacoby Brissett has latched onto Wilson as his top target with Harrison sidelined, making him a popular waiver-wire pickup last week. If Wilson is still available in your league, he needs to be scooped up immediately. It's unclear if Harrison will be ready to return in Week 13 versus the Tampa Bay Buccaneers, but even if he does come back, Wilson should remain involved in a fantastic matchup against a Bucs defense that has given up tons of yardage the last few weeks through the air.
--Keith HernandezSource: ESPN.com
November 23, 2025
Arizona Cardinals quarterback
Jacoby Brissett completed 33 of 49 pass attempts for 317 yards, one touchdown, and zero interceptions in his team's 27-24 overtime Week 12 loss to the Jacksonville Jaguars. Since taking over as the Cardinals' starting QB for the injured
Kyler Murray (foot) in Week 6, Brissett has led one of the league's highest-volume passing attacks. Over his last three games alone, the 32-year-old has attempted a whopping 150 passes. The consistently high volume of throws has helped Brissett put up some impressive counting stats. Across eight games (six starts) in 2025, he's thrown for 1,867 yards, 11 touchdowns, and three interceptions. As long as the Cardinals continue to turn to the air at a high rate, Brissett warrants starting consideration from fantasy managers, even in single-QB formats. Arizona will travel to Tampa Bay to take on the Buccaneers in Week 13.
--Will BradySource: RotoBaller
November 23, 2025
Arizona Cardinals wide receiver
Michael Wilson remains atop the depth chart after
Marvin Harrison Jr. (appendix) was ruled out for Sunday's Week 12 contest against the Jacksonville Jaguars. This will be Wilson's second consecutive game as the top wide receiver in Arizona. He dominated last week's contest, catching a whopping 15 of 18 targets for 185 yards. Quarterback
Jacoby Brissett set the NFL's all-time single-game completion record in that outing, so perhaps Wilson's volume will drop a little in Week 12. Still, he's a strong candidate to fetch double-digit targets. He'll also have a decent chance to score his first touchdown since Week 2, especially against a Jaguars defense allowing the eighth-most touchdowns to wide receivers in 2025. Wilson is a strong fantasy starter in most leagues on Sunday, checking in as the overall WR18 in RotoBaller's latest Week 12 fantasy rankings.
--Andersen PickardSource: RotoBaller
November 23, 2025
Arizona Cardinals wide receiver
Greg Dortch should once again see an expanded role in the receiving game this weekend. Fellow wideout
Marvin Harrison Jr. (appendix) has been ruled out for a second straight game. Last week, Dortch hauled in all six of his targets for 66 yards and a touchdown in the loss to the San Francisco 49ers. Prior to that, Dortch went two straight games without a catch. That being said, Dortch doesn't seem to carry much long-term value, but is worth a look while Harrison is out. Given his success last week, Dortch should once again see a good volume in the passing game. He'll get a favorable matchup against the Jacksonville Jaguars defense that has struggled to contain the passing game. Dortch should be viewed as a flex option for this weekend.
--Andy WebbSource: Pro Football Reference
November 22, 2025
Arizona Cardinals kicker
Chad Ryland has had back-to-back games under five fantasy points for the first time this season. The 26-year-old went one for two with making an extra point attempt during Week 11's matchup against the San Francisco 49ers, making a field goal within the 30 and missing his first field goal on the year from 50-plus yards out. Ryland and the Cardinals will face the Jacksonville Jaguars in Week 12, and they have allowed the 10th most passing yards this season. The Cardinals should be able to move the ball through the air to get Ryland into field goal range quite consistently. Fantasy managers can insert Ryland into lineups as a viable streaming option in Week 12.
--Wyatt McClintockSource: NFL.com
November 22, 2025
The Arizona Cardinals D/ST is looking to bounce back after a rough outing in Week 11 against the San Francisco 49ers. They gave up a season-high 41 points and were unable to force a turnover for the third time this season. In Week 12, the Cardinals D/ST will host the Jacksonville Jaguars, led by turnover-prone quarterback
Trevor Lawrence, without his top receiver,
Brian Thomas Jr. (ankle), who was ruled out with an ankle injury. Lawrence has thrown an interception in each of his last three games and has thrown eight total this season. The Cardinals' D/ST has been able to snag six interceptions this season, and will have top defensive lineman Calais Campbell active to put pressure on the Jaguars' offensive line. With a depleted Jaguars passing attack, the Arizona Cardinals D/ST is worth taking a flyer on this week.
--Wyatt McClintockSource: AZCARDINALS.com
November 22, 2025
Arizona Cardinals running back
Michael Carter saw a spike in targets during Week 11, with a season high of seven targets in Sunday's loss to the San Francisco 49ers. He finished with six yards on two rushing attempts while catching five of seven targets for 22 yards in Week 11. The 26-year-old will remain the change of pace back with teammate
Bam Knight (ankle) suiting up in Week 12 despite battling an ankle injury all week. Carter is RotoBaller's 43rd-ranked running back in PPR Leagues heading into a tough Week 12 matchup against the Jacksonville Jaguars. The Jaguars have allowed the fewest rushing yards and the fourth fewest rushing touchdowns this season. In a limited role, Carter will need to see a heavy workload in the passing attack to stay fantasy-relevant for fantasy managers. Carter is a desperation flex option in deeper PPR Leagues in Week 12.
--Wyatt McClintockSource: AZCARDINALS.com
November 22, 2025
Arizona Cardinals running back
Bam Knight (ankle) was a full participant in Friday's practice and will play in their Week 12 matchup against the Jacksonville Jaguars. Knight had been battling an ankle injury all week, but will lead the Cardinals' backfield with teammate
Emari Demercado (ankle) being ruled out for Sunday with an ankle injury.
Trey Benson (knee) was also ruled out, despite having his 21-day practice window opened earlier this week. Heading into Week 12, Knight is RotoBaller's 31st-ranked running back in PPR Leagues against a stout Jaguars run defense. The Jaguars have allowed the fewest rushing yards and the fourth fewest rushing touchdowns this season. Knight is a touchdown-dependent flex option in a tough matchup against the Jaguars.
--Wyatt McClintockSource: AZCARDINALS.com
November 22, 2025
Arizona Cardinals wide receiver
Greg Dortch is coming off his best fantasy performance this year with six catches for 66 yards and a touchdown in Sunday's loss to the San Francisco 49ers. Heading into Week 12 in a favorable matchup against the Jacksonville Jaguars, Dortch is RotoBaller's 40th-ranked wide receiver in PPR Leagues. The 27-year-old will see an extended role in a pass-happy offense for a second straight week, with teammate
Marvin Harrison Jr. (appendix) ruled out. He will face a Jaguars defense that has allowed the 10th most receiving yards and the fifth most receiving touchdowns this season. Dortch should be viewed as a WR4 with upside in Week 12 and a viable flex option in deeper leagues.
--Wyatt McClintockSource: AZCARDINALS.com
November 22, 2025
Arizona Cardinals wide receiver
Michael Wilson is coming off a historic Week 11 performance against the San Francisco 49ers. The 25-year-old had 15 catches for 185 yards on 18 targets. Wilson finished as the No. 1 wide receiver for the week and has the most receiving yards in a game this season. The former Stanford product will be heavily involved in the offense, with wide receiver
Marvin Harrison Jr. (appendix) being ruled out for a second straight week after undergoing surgery
to address appendicitis. Wilson will face a Jacksonville Jaguars defense that has allowed the 10th most receiving yards this season. In an expanded role, Wilson will have plenty of opportunities to make plays downfield against a vulnerable secondary with quarterback
Jacoby Brissett under center. In a high-volume passing offense in a favorable matchup, Wilson will be a viable flex option for fantasy managers heading into Week 12.
--Wyatt McClintockSource: AZCARDINALS.com
November 22, 2025
Arizona Cardinals tight end
Trey McBride enters Week 12 as RotoBaller's No. 1 overall-ranked tight end and holds Tier 1 to himself. The 26-year-old has set the fantasy world on fire again with back-to-back 27-plus point performances and No. 1 overall finishes. McBride will once again be the focal point of the passing game with wide receiver
Marvin Harrison Jr. (appendix) missing his second straight game after undergoing surgery to address appendicitis. Heading into Week 12, McBride will face a Jacksonville Jaguars defense that has allowed the fifth-most passing touchdowns this season. McBride has caught at least one touchdown pass in his previous five games and has six total touchdowns during that stretch. McBride is a set-it-and-forget-it TE1 with massive upside heading into Sunday in a favorable matchup.
--Wyatt McClintockSource: AZCARDINALS.com
November 22, 2025
Arizona Cardinals quarterback
Jacoby Brissett played his way into the NFL record books for most completions in a regular-season game (47) during Week 11 against the San Francisco 49ers. After a historic performance, the 32-year-old veteran enters Week 12 as RotoBaller's 10th overall-ranked quarterback in a favorable matchup against the Jacksonville Jaguars at home. The Jaguars' defense has allowed the 10th-most passing yards, the fifth-most passing touchdowns, and recorded the third-fewest sacks this season. He should have plenty of time in the pocket to pick apart a vulnerable Jaguars secondary and continue stuffing the stat sheet. Since taking over the offense, Brissett has averaged over 40 passing attempts per game and has taken the Cardinals' passing game to the next level. Brissett should be comfortably inserted into lineups as a QB1 playing in a high-volume passing attack against a struggling defense.
--Wyatt McClintockSource: NFL.com
November 21, 2025
Arizona Cardinals running back
Trey Benson (knee) has officially been ruled out for Sunday's matchup against the Jacksonville Jaguars, according to Tyler Drake of AZSports. Benson was a limited participant in practice every day this week, but the Cardinals ultimately decided to hold him out for another week. Head coach Jonathan Gannon said that the second-year back looked good during practice this week, and that they'd "see how it goes" on Friday in regards to his chances to play in Week 12. It seems like Benson is making progress in his recovery, but he's not quite there yet. He has now been ruled out for his seventh consecutive game and has yet to practice in full capacity, which is likely the next big step for him to take to get back to the field.
Emari Demercado (ankle) has also been ruled out for Sunday, leaving
Bam Knight (ankle) and
Michael Carter to split the backfield duties against the Jaguars.
--Kyle McCarthySource: Tyler Drake
November 21, 2025
According to head coach Jonathan Gannon, Arizona Cardinals running back
Trey Benson (knee) could suit up this weekend for the first time since picking up a meniscus injury in Week 4. "We'll see how he goes today," said Gannon. With the team's backfield at less-than-full health, Arizona could certainly use the 23-year-old back in the fold as they gear up for a home matchup with the Jacksonville Jaguars in Week 12. However, Gannon's sentiment doesn't seem particularly encouraging. Benson has yet to practice in a full capacity since being injured, so you'd have to think the team would like to see him do so before activating him from Injured Reserve. With teammate
Emari Demercado (ankle) already ruled out,
Michael Carter and
Bam Knight (ankle) project to lead the backfield again if Benson sits for another contest.
--Alex CiullaSource: Zach Gershman
November 20, 2025
Arizona Cardinals running back
Michael Carter is trending up ahead of Sunday's Week 12 contest against the Jacksonville Jaguars. The 26-year-old was factored out of the Cardinals' plans in the two games following their bye week, but he returned to a larger role last Sunday, catching five of seven targets for 22 receiving yards. While the sample size is too small to make any guarantees, it certainly appears that Carter could be in line to operate as the Cardinals' top receiving back going forward. He'll earn some carries, too, and managers have to be intrigued after he edged out
Bam Knight for the highest snap share in Arizona's backfield last week. Knight and Carter will split most of the opportunities on Sunday after
Emari Demercado (ankle) was already ruled out for Week 12. Both backs will rank as RB3/flex options, with Carter gaining a slight advantage over his backfield-mate in full-PPR leagues.
--Andersen PickardSource: RotoBaller
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