November 13, 2025
Arizona Cardinals running back
Bam Knight (ankle) was seen at practice for the second straight day on Thursday, according to Dani Sureck of AZCardinals.com. Knight was listed as a limited participant in the team's walkthrough practice on Wednesday after injuring his ankle in the Week 10 loss to the Seattle Seahawks on Sunday. The 24-year-old may need a full practice this week to avoid a questionable tag going into the weekend, but as of right now, two practices suggest he has a chance to be active this Sunday versus the San Francisco 49ers. Since the team's bye in Week 8, Knight and
Emari Demercado have been splitting most of Arizona's backfield touches, with Demercado being the more productive back. Knight hasn't scored since Week 6 and has averaged just 3.4 yards per carry on 33 rushing attempts in his three "starts." If he's active against San Fran, fantasy managers should consider him a low-upside RB3/flex option.
UPDATE: Knight was limited again on Thursday.--Keith HernandezSource: AZCardinals.com - Dani Sureck
November 13, 2025
Arizona Cardinals running back
Trey Benson (knee) could quickly become a hot commodity in fantasy circles as he nears a return from injured reserve. Cardinals head coach Jonathan Gannon said Wednesday that he did not have an update on the running back's status, but he is now eligible to have his practice window opened at any time. Fellow running back
James Conner (ankle) will miss the rest of the year, so Benson figures to have a clear hold of the No. 1 spot in the backfield upon his return, giving Benson rest-of-season potential even if he doesn't play in Week 11. Some redraft managers lost their nerve and dropped him during the IR stint, which would make him an easy addition, but he's also a sensible trade target for managers thinking about making a playoff push.
--Nick PiotrowiczSource: Pro Football Reference
November 13, 2025
Arizona Cardinals wide receiver
Greg Dortch has a pathway to seeing more targets in Week 11 with his team set to play the San Francisco 49ers without top wideout
Marvin Harrison Jr. (appendectomy). The former Wake Forest man scored a rushing touchdown last week, but has not caught a pass since Week 7. Dortch has always been a volatile fantasy option given his unpredictable usage in the Cardinals' offense. In one two-week stretch earlier this year, he played 64% of the team's snaps one week, then 7% the next. He'll still be solidly behind tight end
Trey McBride and wide receiver
Michael Wilson this week, but the absence of Harrison opens the door for more usage. Managers in deeper leagues who need a Week 11 fill-in can consider him a high-risk, high-reward option.
--Nick PiotrowiczSource: Greg Dortch
November 13, 2025
Arizona Cardinals wide receiver
Michael Wilson has seen his fantasy value surge with his team set to play Week 11 without top wide receiver
Marvin Harrison Jr. (appendectomy). Tight end
Trey McBride continues to be the team's No. 1 pass catcher, but Wilson is third on the team in most receiving categories and should be the No. 1 receiver this week. The Cardinals, who have had a rotating cast of running backs and are playing with backup quarterback
Jacoby Brissett, have been one of the toughest teams to gauge in the NFL for fantasy leagues. Wilson is earning a middling 6 yards per target and has only 22 catches through nine games, so managers shouldn't expect a week-winning performance, but Wilson's likely increase in volume could be worth a look in deeper leagues or as a one-week fill-in.
--Nick PiotrowiczSource: Pro Football Reference
November 12, 2025
Arizona Cardinals running back
Emari Demercado could see an increased workload heading into the team's Week 11 matchup with the San Francisco 49ers. With
Bam Knight (ankle) a limited participant in Wednesday's practice, Demercado may build on his career-best performance last week, where he picked up 104 yards from scrimmage on just seven touches. The 26-year-old back is likely to see heavy usage moving forward, with quarterback
Jacoby Brissett poised to get the ball out quickly to his playmakers.
--Shaun AlbinSource: Arizona Cardinals
November 12, 2025
Arizona Cardinals running back
Bam Knight (ankle) was a limited participant during Wednesday's practice. This doesn't come as a shock after Knight was forced to exit during the fourth quarter of Sunday's game against the Seattle Seahawks due to an ankle issue. He'll open the week as a limited participant, but the Cardinals likely want to be cautious to begin the week. Lately, Knight has been splitting up the reps with
Emari Demercado in the backfield. Demercado and
Michael Carter would take over the backfield duties if Knight misses the Week 11 matchup against the San Francisco 49ers. Fantasy managers will need to check back on Thursday for another update on Knight.
--Andy WebbSource: Bo Brack
November 12, 2025
Arizona Cardinals wide receiver
Zay Jones (Achilles) tore his Achilles in last week's loss to the Seattle Seahawks on Sunday and will miss the rest of the season, according to Adam Schefter of ESPN. Additionally, the Cardinals will be without top wideout
Marvin Harrison Jr. "this week and possibly longer" after he underwent surgery for appendicitis. Arizona's receiving corps will be very thin for quarterback
Jacoby Brissett on Sunday against the division-rival San Francisco 49ers. Tight end
Trey McBride should be a target hog, with
Michael Wilson and
Greg Dortch stepping up as the top two receiving options in the passing attack. Jones, 30, wasn't really on the fantasy radar to begin with in 2025 in a struggling Cardinals offense. He will finish with just 12 catches for 183 yards and no touchdowns in his eight games played.
--Keith HernandezSource: ESPN - Adam Schefter
November 12, 2025
Arizona Cardinals head coach Jonathan Gannon did not have an injury update on running back
Bam Knight (ankle) on Wednesday, according to Theo Mackie of The Arizona Republic. Knight, who has become the Cardinals' primary option in the backfield in recent weeks with
Trey Benson (knee) on Injured Reserve, picked up an ankle injury in the fourth quarter of the Week 10 loss to the Seattle Seahawks. The 24-year-old only had 28 rushing yards on 10 carries in the blowout loss before leaving, adding one catch for five yards. Fantasy managers will want to check back on Knight's practice status on Wednesday. Benson has yet to resume practicing, so he feels unlikely to make his return this Sunday against the division-rival San Francisco 49ers. Fantasy managers in need of RB help may want to pick up
Emari Demercado now in case Knight is unable to go this weekend.
--Keith HernandezSource: The Arizona Republic - Theo Mackie
November 12, 2025
Arizona Cardinals head coach Jonathan Gannon did not give an update on running back
Trey Benson (knee) on Wednesday, according to Theo Mackie of The Arizona Republic. Benson was eligible to return from Injured Reserve and play in Week 10, but that did not happen, and it remains unclear if he'll have his 21-day practice window opened this week. At the very least, it doesn't look likely that the 23-year-old second-year back will come off IR to play this Sunday against the division-rival San Francisco 49ers. The Cardinals also don't have an update on
Bam Knight (ankle), who picked up an ankle injury in the Week 10 loss to the Seattle Seahawks. With Benson not expected to return this week and Knight's status up in the air,
Emari Demercado could be Arizona's primary option in the backfield this weekend.
Michael Carter would also see an uptick in touches if both Benson and Knight are ruled out.
--Keith HernandezSource: The Arizona Republic - Theo Mackie
November 12, 2025
ESPN's Adam Schefter reports that Arizona Cardinals wide receiver
Marvin Harrison Jr. (appendix) underwent surgery for appendicitis and will be sidelined for "at least this week and possibly longer." It's a tough blow for the 23-year-old, who had recorded 10 catches for 129 yards and two touchdowns on 22 targets over the last two weeks. Harrison Jr. will now miss his team's Week 11 matchup against the San Francisco 49ers, and it appears there's no guarantee he'll be back in Week 12 to face the Jacksonville Jaguars. Without Harrison Jr. on the field, Arizona tight end
Trey McBride could see an even larger target share. Additionally, Cardinals wideout
Michael Wilson could be in line for significantly more looks from quarterback
Jacoby Brissett. Wilson saw a season-high seven targets in Week 10 and may be in for another target spike in Week 11.
--Will BradySource: ESPN - Adam Schefter
November 12, 2025
Arizona Cardinals running back
Trey Benson (knee) is nearing a return to action in the coming weeks. Benson underwent arthroscopic knee surgery after Week 5 and was placed on injured reserve. The typical recovery timeline for a meniscus clean-up is four to six weeks, which puts him right on schedule entering Week 11. Before the injury, Benson logged 224 scrimmage yards on 41 touches across four games while mostly serving as the backup to
James Conner. With Conner now out for the season, Benson is expected to step into the RB1 role once healthy. Fantasy managers should view him as a strong buy-low candidate who could make a significant impact down the stretch.
--Nathan HarveySource: Pro Football Reference
November 11, 2025
Despite increased involvement in the Arizona Cardinals' backfield of late, running back
Emari Demercado is listed as the No. 2 RB behind
Bam Knight heading into the team's Week 11 divisional clash with the San Francisco 49ers this Sunday. Knight made the start in Sunday's blowout loss to the Seattle Seahawks and led the backfield with 10 carries before leaving late in the game with an ankle injury. Knight's ankle injury doesn't seem to be serious enough to keep him from playing this weekend, which makes the 26-year-old Demercado less attractive as a potential DFS sleeper against San Fran. Trying to predict Arizona's backfield since
Trey Benson's knee injury has been a headache for fantasy managers, although as long as he stays healthy, Knight appears to be the guy in more of a committee approach. Dermercado had a season-high 14 carries for 79 yards on Nov. 3 against the Cowboys, but he handled only eight touches in Week 10, going for 67 scrimmage yards. It's hard to recommend any Cardinals RB in fantasy as anything more than a desperation RB3/flex until Benson returns from IR.
--Keith HernandezSource: Arizona Cardinals Insiders
November 11, 2025
Arizona Cardinals running back
Bam Knight is still listed as the team's RB1 on the depth chart ahead of their Week 11 matchup against the San Francisco 49ers. Knight has maintained a narrow edge in snaps over
Emari Demercado over the past two weeks, playing 71 snaps to Demercado's 56. The 24-year-old Knight has ceded more work on passing downs, but has handled four of the seven carries inside the 10-yard line in the past two games.
Trey Benson (knee) is expected to return soon and should retain his duties as the lead back, but his timeline is still uncertain as of now. Knight will remain in RB3 territory in Week 11 if Benson is out.
--Kyle McCarthySource: Arizona Cardinals
November 11, 2025
Arizona Cardinals quarterback
Jacoby Brissett has posted solid numbers since moving into the starting role, and he'll keep the starting job while
Kyler Murray (foot) spends at least the next three weeks on IR. Brissett has thrown for over 250 yards in each of his four starts and has thrown for exactly two touchdowns in each outing. He added a touchdown run as well in the team's win over the Cowboys in Week 9, and in Week 10, he threw for 258 passing yards on 44 pass attempts against the Seahawks. Coach Jonathan Gannon has shown plenty of trust in Brissett to air it out, and this week, he has a favorable matchup against the 49ers. San Francisco has allowed the ninth-most fantasy points to quarterbacks this season, so Brissett is definitely worth a look as a streaming option or as a QB2 in Week 11.
--Zach ThompsonSource: RotoBaller
November 10, 2025
The Arizona Cardinals will place wide receiver
Zay Jones (Achilles) on Injured Reserve with an Achilles injury that he suffered in the Week 10 blowout loss to the Seattle Seahawks on Sunday, according to Zach Gershman of AZCardinals.com. Jones wasn't really on the fantasy radar to begin with in standard-sized leagues, but now he'll be forced to miss at least the next four games for the Cardinals. The 30-year-old veteran pass-catcher had only 12 catches on 18 targets for 183 yards and no touchdowns through eight games this year in a struggling Cardinals passing game. With Jones out for the foreseeable future,
Greg Dortch should see more targets, but he's only worth a waiver-wire pickup for WR depth in deeper leagues. The earliest that Jones will be able to return will be for a Week 15 matchup on Sunday, Dec. 14, against the Houston Texans on the road.
--Keith HernandezSource: AZCardinals.com - Zach Gershman
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