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Nov 14, 2025, 2:54 PM ET

Kansas City Chiefs running back Isiah Pacheco (knee) has officially been ruled out for his team's Week 11 matchup against the Denver Broncos, per Ian Rapoport of NFL Network. This will mark Pacheco's second straight missed game after he suffered an MCL sprain in Week 8. Without him, Kansas City will likely turn to veteran running back Kareem Hunt to handle the majority of their backfield work. Hunt recorded 11 carries for 49 yards and a touchdown in Week 9 against the Buffalo Bills with Pacheco sidelined. Rookie running back Brashard Smith could mix in as well, but Smith earned just four touches against Buffalo. Hunt profiles as a borderline RB2/high-end flex option for fantasy managers in Week 11. Pacheco should have a chance to return to the field in Week 12 when the Chiefs host the Indianapolis Colts.--Will Brady
Source: NFL Network - Ian Rapoport
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