👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


NFL Betting Picks For Week 2 - Best Bets, Expert Odds and Predictions

Antonio Gibson - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Steve Janik's top NFL betting picks and best bets for Week 2 of the 2022 NFL season. His free picks target the under, over and the moneyline.

We got off to a positive start for the 2022 NFL season, going 2-1 including a +118 money line whit with the Browns winning in walk-off field goal style over the Panthers. I'll continue to look for these +EV moneyline plays as the season rolls on, but finding value earlier in the season is much easier than as the year rolls on.

I have always and will always put the disclaimer of **I'm not a professional.** I do this for fun, use my free time to research my favorite plays, and give a little of my insight into why I'm doing a particular play. My goal is to provide you with information that can help you make informed bets, whether you agree or disagree with me.

  • 2022 Record: 2-1, +1.08 units
  • Spread: 0-0
  • Total/Team Total: 1-1, -.1 units
  • Moneyline: 1-0, +1.18 units
  • Props: 0-0

Be sure to follow me on the Twitter machine @stevejanik6 and on Action Network, where I'll have all of my bets this season. It's not only a goal to have a better season, but I'm looking for more engagement on Twitter this season, so feel free to hit me up! Now down to the nitty-gritty - please remember this is all for entertainment. With that, I hope you enjoy it, best of luck, and please bet responsibly!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Week 2 NFL Betting Picks - Totals

New England Patriots (-2) at Pittsburgh Steelers

Sunday 9/18, 1:00pm PM EST | O/U: 40.5

The Patriots had a bit of a stunner in Week 1, falling 20-7 to the Dolphins. The offense was beyond anemic, amassing just 271 yards of offense. Mac Jones turned the ball over twice and by the end of the game was experiencing some back spasms, so overall it was just a down day. The run game was serviceable, as Damien Harris and Rhamondre Stevenson averaged 4.3 yards per carry as a duo, but with the overall lack of success on offense, the Pats were just plain flat.

Things won't get easier in Week 2 as they travel to Pittsburgh who is fresh off a five-takeaway game. While Jones is expected to play, it will be interesting to see how they attack after a week of game prep. New England was one of the slowest-paced teams in Week 1, averaging just over 30 seconds between offensive plays. I wouldn't be surprised to see this pace continue to try and kill any momentum the Steelers' defense tries to build.

The Steelers quite frankly didn't deserve to win against the Bengals in Week 1. If there was an offense that looked worse than the Patriots, it was the Steelers. Mitch Trubisky got little protection, and when he did, he made very bad decisions. Najee Harris (foot) reaggravated a training camp injury and is questionable for this one. If he doesn't play, it will put even more pressure on Trubisky to make plays, which is not what the Steelers want to gameplan for.

Pittsburgh's defense was very much back, after registering five takeaways from the Bengals. However, TJ Watt (pectoral) is out for a few weeks, which puts a damper on the pass rush. However, this defense is still dangerous enough that putting Mac Jones in pressure situations won't be hard to do.

Under Mike Tomlin, the Steelers are notorious for getting off to slow starts in games. Last week, they kept their pace slow (30 seconds in between snaps). As previously mentioned the Pats were slow in Week 1, but especially slow in the first half (34 seconds in between snaps) and didn't cross their opponent's 40-yard line in the entire first half. While I don't think they'll struggle quite that bad again, I look for this first half to be slow and uneventful.

Pick: 1H Under 20 (-110, Fanduel) Bet to win 1 Unit

 

Carolina Panthers at New York Giants (-1.5)

Sunday 9/18 1:00PM EST | O/U: 43.5

Baker Mayfield wasn't exactly the game changer Carolina was hoping for in Week 1, but he did enough to give the team a chance to win. After all, Christian McCaffrey is the be-all, end-all of this team, and even he was held in check by the Browns defense. As a unit, they put up 261 yards of offense and scored 17 of their 24 points in the fourth quarter. Realistically, this is the type of game we can expect out of Mayfield, but with CMC, it's just a matter of when, not if he goes nuts.

The Panthers' run unit was easily the worst in all of Week 1, after giving up 217 yards to Nick Chubb and Kareem Hunt, and Football Outsiders and ProFootballFocus agree, based on their ratings. Now they get Saquon Barkley who looked revitalized in his first game back.

The Giants are in a weird place in that they have a franchise player at running back and a new coach who has been heralded for his play-calling abilities. However, their quarterback is considered one of the worst in the league. Yet, they found a way to beat the Titans in Week 1. Daniel Jones is that culprit, and while his numbers look serviceable (17 for 21 with 188 yards and two touchdowns), the majority of that success was in the second half. Saquon Barkley rushed for 168 and a score and looks as good as new.

This defense is on the same level as the Browns after Week 1. However, their downfall was the passing game, allowing 288 yards and two touchdowns and sitting as the 31st worst pass defense by DVOA. Again, small sample. They held Derrick Henry to just 82 yards and no scores but got dissected by Ryan Tannehill. Could we see a similar outcome in Week 2, as the matchup seems eerily similar?

I think Barkley is going to run up, down, and around the Panthers on Sunday. I think Mayfield throws for over 300 yards against this weak Giants secondary. I picked up the total when it opened at 42.5 and it has since gone up to 43.5, but I see upside for both offenses this week, and I think the over is the play.

Pick: Over 42.5 (-110, Draftkings) Bet to win 1 Unit

 

Sports Betting Promo Offers

Featured Promo: Get any Betting Premium Pass for 50% off using code SPRING. Win more with exclusive betting picks from proven winners across 9 sports! Find optimal bets with our Betting Picks Tool and Bet Weighting Tool and follow along in our VIP chat rooms! Go Premium, Win More!

 

Week 2 NFL Betting Picks - Moneyline

Washington Commanders at Detroit Lions (-1.5)

Sunday 9/18 1:00PM EST | O/U 48.5

All things considered, it was a great start to the year for the Commanders when they won 28-22 over the Jaguars in Week 1. New quarterback Carson Wentz showed promise with his receiving corps, tossing for over 300 yards with four touchdowns. Of course, two interceptions bring that down a bit, but overall the offense moved the ball and many players had an impact, including rookie receiver Jahan Dotson, who caught his first two career touchdowns.

Defensively, the Commanders are suspect. They're missing Chase Young, but in Week 1, they registered a 68 rating for pass rush by ProFootballFocus, so against a banged-up Lions offensive line, it's imperative that type of pass rush continues.

The Lions put up a heck of a fight against the Eagles last week. They lost 38-35 and outscored Philly 21-14 in the second half. Jared Goff did what the team needed him to do and that was spread the ball around and limit mistakes. He threw two touchdowns and one interception, but it was enough to allow the run game to succeed to the tune of 181 yards and three touchdowns between D'Andre Swift and Jamaal Williams. Swift wound up on the injury report during the week but is expected to go Sunday.

The Lions' defense got absolutely gashed by the Eagles. Four different Philly players scored a rushing touchdown in Week 1, and while the Commanders will likely have a different game plan, this unit is not strong. Aiden Hutchinson is a stud and will generate pressure on Wentz, but outside of him, there's a lot to be desired. They come into this ranked 28th in DVOA, though obviously a small sample.

The Lions are without a doubt making positive strides, but I'm not there quite yet on buying in. I give Washington advantages at the quarterback, wide receiver, and on defense. With the spread at 1.5, it's essentially a toss-up, but I'm siding with the slight road underdog here and taking the Washington money line and hoping Wentz doesn't completely blow this one up.

Pick: Washington Commanders ML (+118) Bet 1 Unit

 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Advice




RANKINGS

QB
RB
WR
TE
K
DEF

RANKINGS

QB
RB
WR
TE
K
DEF

REAL-TIME FANTASY NEWS

Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Jalen Hurts

Can Jalen Hurts Bounce Back as a Rusher in 2026?
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Zach Charbonnet

Dynasty Value in Question Entering 2026
DeVonta Smith

Poised to Reach a New Level of Production in 2026?
Chris Olave

Facing Increased Target Competition in New Orleans Entering 2026
Chris Bell

Dynasty Stock Rising Following NFL Draft
Ted Hurst

Facing Uphill Battle for Playing Time in Tampa Bay
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
Chris Brazzell II

Is Chris Brazzell II the Top Deep Threat in Carolina's Receiver Room?
Kaelon Black

a Threat to Win Backup RB Job in San Fran?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
De'Zhaun Stribling

to be 49ers' New "F" Receiver?
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
Drew Allar

Steelers "Uninstalling" Everything Drew Allar Learned in College
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Ja'Kobi Lane

Is Ja'Kobi Lane the Pass-Catching Answer the Ravens Have Been Seeking?
Zachariah Branch

Does Zachariah Branch Have a Path to Immediate Production?
Max Klare

Can Max Klare Separate Himself in Rams' Tight End Room?
Eli Stowers

the Tight End of the Future in Philadelphia?
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Germie Bernard

Already in a Tough Spot to Hold Dynasty Value
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Denzel Boston

a Smart Bet to Meet or Exceed Value in Dynasty Rookie Drafts
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Matthew Stafford

a Sell Candidate with Touchdown Regression Likely on its Way
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Jayden Reed

Dynasty Value Tethered to His Underwhelming Usage
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Kenyon Sadiq

Is Kenyon Sadiq the Next Great Rookie Tight End?
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Sidney Crosby

Joins Team Canada for World Championship
Ryan Poehling

Suffers Upper-Body Injury in Game 5 Loss
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Cade Klubnik

Becoming Fan Favorite, in Play to Win Backup QB Job?
Michael Penix Jr.

Throwing During Offseason Program
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Dylan Harper

Cleared for Action Tuesday
De'Aaron Fox

Available for Game 5 Against Timberwolves
Caris LeVert

Remains on Injury Report With Heel Issue
Duncan Robinson

Listed as Questionable for Game 5
Memphis Grizzlies

Brandon Clarke Dies at Age 29
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Sam Malinski

Day-to-Day With Upper-Body Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Artturi Lehkonen

Considered Day-to-Day
Charlie Coyle

Lands Six-Year Extension
Ukko-Pekka Luukkonen

to Start Game 4 Against Canadiens
Drew Helleson

Unavailable for Game 5
Radko Gudas

Still Out Tuesday
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
Luka Dončić

Luka Doncic Admits He Wasn't Close to Returning Before Season Ended
CFB

Isaac Brown Has All-American Upside in 2026
LeBron James

Uncertain About Future After Season-Ending Loss
Ajay Mitchell

Continues to Excel for Thunder
CFB

Nyck Harbor Heading into Breakout Year?
Shai Gilgeous-Alexander

Posts 35 Points in Series Clincher
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
Cade Cunningham

Struggles in Game 4 Loss
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas