🖥 CYBER WEEK - TAP TO SAVE 50% WITH CODE CYBER
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Midwest Region: March Madness Bracket Predictions

NCAA Tournament - March Madness College Basketball

NCAA Tournament bracket picks and team predictions for the Midwest Region. Read Seth's March Madness picks, sleepers and busts including teams to target and avoid.

March Madness is officially here, so let's fill out some winning brackets! RotoBaller will be bringing you a full breakdown on each tournament region, including some potential sleepers and busts. Today we'll be taking a look at the Midwest Region and my bracket picks.

I'm here to tell you some teams that I believe in to help you make the right tournament bracket decisions. Below I analyze the top four seeds, a potential bust, and a potential final four candidate. Hopefully, my college basketball predictions can help you win your March Madness pools. I really like to use Ken Pomeroy's advanced analytics to help determine a champion. Since 2002, each team to win the title except for one, was ranked top-20 in both offensive and defensive efficiency. I'll be putting those numbers in parentheses after each breakdown of the top-four seeds. Now let's get to it.

Once you're done here, be sure to also check out the rest of our NCAA Tournament articles and analysis including previews, predictions, sleepers, busts and guides on how to fill out your including other predictions for the East, South, and West regions.

Cyber Week Special! Save 50% on any Premium Pass using discount code CYBER. Win more with our DFS, Betting and Season-Long Premium Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

Midwest Region Top Four Seeds 

Top four seeds: No. 1 Illinois | N0. 2 Houston | No. 3 West Virginia | No. 4 Oklahoma State

Illinois is the hottest team in the country. They've won seven in a row, including wins over Michigan and Ohio State twice, the second coming in the Big 10 championship. Ayo Donsunmu is a star. They'll make a deep run. (Ken Pom: #7 offense, #5 defense)

Houston will not be a popular play. People don't know much about them but they can score a lot and play really good defense. (Ken Pom: #8 offense, #16 defense)

West Virginia is seeded too high. You'd think a Bob Huggins coached team would play good defense, but they don't. They won't make it out of the first weekend. (Ken Pom: #11 offense, #65 defense)

Oklahoma State will be a very popular pick because of likely number one overall pick Cade Cunningham. But they have a very difficult first-round matchup against Liberty. The Flames have a good cast of upper and lower classmen. They beat Mississippi State as the No. 12 seed in the NCAA Tournament two years ago. Last year they won their conference tournament and were going to do damage. Now, no one is giving them a chance. (Ken Pom: #54 offense, #22 defense)

 

Most Intriguing First Round Matchup

No. 6 San Diego State vs. No. 11 Syracuse

Of course, Syracuse makes the tournament and isn't even a last four in. They're always given the benefit of the doubt by the committee. The Aztecs are favored by two so this will go down to the wire. San Diego State has won 14 in a row. They play a slow methodical physical game. First to 60 wins. And the winner will likely be headed to the Sweet 16.

 

Bust of the Region

Oklahoma State. They'll go as far as Cade Cunningham takes them. If he has a bad game, they'll be out in the First Round. I'm going to take Liberty over the Cowboys in that game.

 

Final Four Pick

Houston. If you want to win your pool, you'll need to take a shot and not go with the popular chalk. Everyone will have Illinois out of this region. Illinois vs. Houston has the potential to be an epic Elite Eight game.

More March Madness Brackets Advice




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
Patrick Williams

Dalen Terry Available Versus Pacers
Coby White

Returns With Minutes Restriction Friday
Ayo Dosunmu

Out Friday Against Pacers
Zach Collins

Available for Season Debut Friday
Robert Williams III

Donovan Clingan Out, Robert Williams III in for Portland Friday
Evan Mobley

Ready to Play Friday
Kristaps Porzingis

Coming Off the Bench Friday
Spencer Jones

Available Against Hawks
OG Anunoby

Returns to Knicks LIneup Friday
Tre Mann

Misses Third Consecutive Game
Ryan Kalkbrenner

Available Friday
LaMelo Ball

Upgraded to Available
Brandon Miller

Returns to Action Friday
Steven Adams

Alperen Sengun Out Friday, Steven Adams Starting
Ozzy Wiesblatt

to Miss 8-10 Weeks With Upper-Body Injury
Jalen Johnson

Returning To Atlanta's Lineup On Friday
Pierre-Olivier Joseph

Out With Illness Friday
Evander Kane

Doubtful for Friday
Jusuf Nurkić

Jusuf Nurkic Questionable For Friday Night
Conor Garland

Back From Two-Game Absence Friday
Tyler Herro

Sitting Out Of Friday's Game
Thomas Harley

Could Be an Option Next Week
Daniel Gafford

Out For Friday Night's Game
Mikael Granlund

Returning From 10-Game Absence Friday
P.J. Washington

Won't Suit Up Friday Night
John Carlson

Misses Second Consecutive Game Friday
Rome Odunze

has Fractured Foot, Labeled Week-to-Week
Brandon Miller

Trending Toward A Return To The Court
Paul George

Avoids Injury Report On Friday
Sauce Gardner

Ruled Out for Sunday
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Aaron Jones Sr.

Cleared to Play in Week 14
Chris Olave

Listed as Questionable for Week 14
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Alvin Kamara

Ruled Out for Sunday
Brandon Moreno

Searches For His Third Win In A Row
Rome Odunze

Ruled Out for Week 14
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Drake London

Ruled Out vs Seattle
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Lamar Jackson

Will Play on Sunday
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
Dalton Kincaid

to be Questionable for Week 14
Tee Higgins

Clears Concussion Protocol, is a Full-Go for Sunday
CFB

Jam Miller Unlikely to Play in SEC Title Game
CFB

Penn State Expected to Hire Matt Campbell from Iowa State
Mike Evans

Not Quite Ready to Return This Week
Jayden Daniels

Will Start Against Vikings
Lamar Jackson

Returns to Practice, on Track to Play on Sunday
Kyler Murray

Won't Return This Year, Cardinals Non-Committal on his Future
Trey Benson

Out in Week 14; Could he Miss the Rest of the Season?
Marvin Harrison Jr.

Ruled Out for Sunday's Game
CeeDee Lamb

in the League's Concussion Protocol
Brian Branch

Out with Torn Achilles
Detroit Lions

Brian Branch Feared to Have Suffered an Achilles Injury
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jayden Daniels

Tracking Towards a Week 14 Return
Justin Herbert

Trending in the Right Direction to Play Monday Night
Mathew Barzal

Leads Islanders Past Avalanche
Elias Lindholm

Posts Hat Trick of Assists Thursday
Leon Draisaitl

Notches Season-High Four Points in Thursday's Win
Connor McDavid

Nets 13th Career Hat Trick
Teuvo Teravainen

Expected to Be Fine After Thursday's Exit
Shane Pinto

Exits Loss With Injury
Joseph Woll

Sustains Lower-Body Injury Thursday
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
Kirill Marchenko

Returns From Four-Game Absence
Carter Verhaeghe

Ready to Return Thursday
Scott Wedgewood

Skips Thursday's Game
Danila Yurov

Misses Second Straight Game
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
Andrei Vasilevskiy

Unavailable Thursday
CFB

Buster Faulkner Set to Become Florida's New Offensive Coordinator
David Pastrnak

Still Out Thursday
Ryan McDonagh

Lightning Sign Ryan McDonagh to Three-Year Extension
CFB

Joe Sloan Expected to be Kentucky's New Offensive Coordinator
CFB

Lane Kiffin Working to Keep Defensive Coordinator Blake Baker at LSU
CFB

Brian Daboll a Candidate for Penn State Head-Coaching Job?
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
CFB

Brent Key Signing Five-Year Deal to Remain at Georgia Tech
CFB

Brian Hartline Expected to Land USF Head-Coaching Job
CFB

Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
CFB

Chris Klieman Considering Stepping Down at Kansas State
CFB

D.J. Durkin Staying at Auburn Under Alex Golesh
CFB

Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP