X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

FanDuel NFL DFS Lineup Picks for Week 3 - Daily Fantasy Football

Patrick Mahomes - Fantasy Football Rankings, DFS Lineup Picks, NFL Injury News

Dennis Clausen highlights the top FanDuel NFL DFS lineup picks for Week 3 of the 2021 season, and some value sleepers for your daily fantasy football rosters.

Week 2 is behind us. Still, it's imperative to acknowledge some of the impressive DFS performances, beginning with Tom Brady, who threw five touchdowns against the Atlanta Falcons, while Kyler Murray had another majestic outing, throwing for 400 yards against the Minnesota Vikings. Going down the rest of the list, Derrick Henry and Aaron Jones combined for seven total touchdowns, and at the wideout position, Cooper Kupp totaled 32.3 fantasy points against the Colts, and Tyler Lockett accumulated 178 yards and a touchdown off eight catches against the Tennessee Titans.

Week 3 will begin with a Thursday Night Football showdown between Sam Darnold and the undefeated Carolina Panthers squaring off against the Houston Texans at NRG Stadium. Of course, as we head toward the Sunday slate of contests, there are some injuries to monitor. Dalvin Cook is dealing with a sprained ankle, Josh Jacobs continues to be plagued by a bad toe and ankle, and Saquon Barkley will look to increase his workload after undergoing knee surgery in October. Nonetheless, if any of these guys are out, there will be some value opportunities without a doubt.

In this article, I will be providing you with my Week 3 daily fantasy football lineup picks for FanDuel’s “Main Slate.” These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Feel free to give me a follow on Twitter @DennisMClausen. Also, be sure to check back on Saturday night and Sunday morning for updates heading into Week 2.

Be sure to check all of our fantasy football rankings for 2025:

Article Updated: Saturday, September 25 @10:30 pm

It's late on Saturday night, but a good time to start examining how to attack Week 3. There have been a few updates throughout the day, some that could change the landscape of roster construction for Sunday. Lamar Jackson remains questionable with the stomach bug. However, it would be surprising if he didn't suit against Detroit.

However, Dalvin Cook and Darrell Henderson Jr. appear to be heading in the opposite direction, which will ultimately make guys like Sony Michel and Alexander Mattison see a significant increase in fantasy interest. Still, managers shouldn't be sold that either is a lock to produce, so pivoting off of those two could pay off.

 

FanDuel Quarterbacks - Week 3 Picks

Patrick Mahomes, QB - @ LAC ($8,700)

Mahomes didn't get much recognition after his impressive showing during the overtime loss to Baltimore on Sunday Night Football. Instead, his brother, Jackson, received most of the attention, primarily after he was caught on video pouring water on a heckling Ravens fan. Unfortunately, the viral video overshadowed just how well the Chiefs' signal-caller has played throughout the first few weeks of the 2021 campaign.

Mahomes is playing better than ever this season, averaging 340 passing yards per contest and throwing six touchdowns in total. He also has a quarterback rating of 131.4, which is fantastic, and he only has one erroneous toss to his credit. Of course, as we examine the Week 3 matchups, it doesn't take long to realize that Vegas has Kansas City as the highest-scoring team on the slate. This game is also predicted to run close, which should allow the former MVP plenty of chances to make some noise on the fantasy end.

Kirk Cousins, QB - vs. SEA ($7,700)

Cousins has played as well as anyone could hope. Before the year started, the veteran was in the news. However, it wasn't for a good reason, as many questioned his ability to lead a team. Since then, things have settled down on that front, and Cousins quietly continues to build on to an efficient 2021 season.

The 33-year-old has historically been an accurate passer over the years. Yet, he has improved even more and is currently sitting on a 71.6 completion percentage and a 112.9 passer rating, both career-highs. Cousins' Week 3 opponent, the Seattle Seahawks, hasn't impressed on the defensive end this season either. As a result, he is someone to consider, especially with Dalvin Cook (possibly), Adam Thielen, and Justin Jefferson at his disposal.

Also Consider:

Kyler Murray, QB - vs. Jac ($9,000)

Murray could end up being one of the most rostered options at the position. However, keep in mind that the Cardinals are playing Jacksonville, a team that should get beat up pretty badly. DeAndre Hopkins is also in danger of sitting. Still, Murray can do so much using his legs and is capable of racking up plenty of fantasy points before the game gets out of

Josh Allen, vs. WAS ($8,000)

After getting more than enough attention in DFS columns for Weeks 1 and 2, Allen has been flying under the radar entering Week 3 against the Washington Football Team. Vegas' projections are favorable for the signal-caller, and he has just as good a chance as others to finish as the top quarterback on the slate.

Tom Brady, QB - @ LAR ($7,800)

Rolling with Brady in Week 3 can surely pay off, especially for DFS managers looking to save some cash by avoiding Patrick Mahomes or Kyler Murray. The GOAT will be without Antonio Brown. Yet, he still has Chris Godwin, Mike Evans, and Rob Gronkowski to keep him in the running as one of the most lethal options on the slate.

Matthew Stafford, QB - vs. TB ($7,600)

Stafford arguably has the most talented group of wideouts he has ever had at his disposal. He will also have plenty of opportunities to put up some numbers in a game that should be a shootout.

 

FanDuel Running Backs - Week 3 Picks

Joe Mixon, RB - @ PIT ($6,700)

During Cincinnati's season opener against the Vikings, Mixon carried the pigskin 29 times, resulting in 127 yards and a touchdown to finish out the afternoon. That performance was definitely welcomed by fantasy managers, especially since he missed most of last year because of a foot ailment.

Naturally, many believed Mixon could produce a similar showing in Week 2 against Chicago. He did have 20 touches in that one, which was good. However, he only managed to scrounge together 69 yards on the ground while only catching one of his two targets. Nonetheless, the Bengals will face a familiar foe on Sunday, the Steelers, a team that the former Sooner has encountered many times throughout his career. He has played relatively well against Pittsburgh, too, amassing 5.5 YPC throughout six meetings. He should be a featured piece of the Bengals' offensive approach in Week 3, and after an average performance against Minnesota, his rostering cost took a considerable dip.

Saquon Barkley, RB - vs. ATL ($6,000)

After suffering a season-ending knee injury in 2020, Barkley wasn't a lock to play this early in the year. Yet, after he began the season with some restrictions, he seems to be moving in the right direction.

The former Nittany Lion finished Week 1 against the Denver Broncos by logging just 10 carries. Then, with a Thursday Night Football showdown against Washington just four days later, he touched the ball a few more times. He has been limited at practice throughout the week, but he could see a noticeable bump in snaps, mainly after getting some additional rest. Barkley was once considered the top fantasy back in the league, and with a rostering cost of $6,000, managers should be willing to take a chance on him in Week 3 against Atlanta.

Also Consider:

Derrick Henry, RB - vs. IND ($9,700)

Henry fell off the map in Week 1 but got his revenge in Week 2 by dumping nearly 45 fantasy points on the Seattle Seahawks. Vegas has him finishing with the most rushing yards in Week 3, so that's as good of a reason to keep him in mind, assuming managers are willing to pay nearly $10,000 for his DFS services.

 

FanDuel Wide Receivers - Week 3 Picks

Tyreek Hill, WR - vs. LAC ($8,700)

With Patrick Mahomes expected to lead all quarterbacks in production in Week 3, it is only logical to pair him up with his favorite receiver. This is as good of a stacking opportunity as it can get, mainly with Kansas City potentially putting up a ton of points against the Chargers.

The 27-year-old got off to a fantastic start to the new year. He was targeted 15 times in Week 1, hauling in 11 receptions for nearly 200 yards and a touchdown. Yet, he fizzled against the Baltimore Ravens during Sunday Night Football and only came away with three catches for a miserable 14 yards. Fantasy managers should certainly give Hill a free pass for that performance, as he has a great chance to rebound in Week 3.

Cooper Kupp, WR - vs. TB ($7,900)

Kupp has arguably been the best wideout in the league this season. After Jared Goff was sent to Detroit in exchange for Matthew Stafford, he appears to be meshing quite well with his new signal-caller. He currently ranks first in receptions (16), sixth in targets (21), and third in receiving yards (271).

Although his effectiveness throughout the first two weeks of the year doesn't mean anything in terms of his Week 3 potential, his ceiling remains as high as ever. With the contest against the Tampa Bay Buccaneers foreseen to feature two gunslingers airing it out, Kupp should stay in the conversation as a must-start DFS option in all formats. Managers should consider that he will undoubtedly see a ton of interest, although pivoting here may not be wise.

Also Consider:

Stefon Diggs, WR - vs. WFT ($7,700)

Diggs had just four catches in Week 2 against the Miami Dolphins. However, he's been targeted 21 times by Josh Allen this season, and for the price, managers should be more than eager to get him back in their DFS lineups on Sunday.

DK Metcalf, WR - @ MIN ($7,200)

Metcalf has been overshadowed by the superior play of his teammate, Tyler Lockett, over the last few weeks. With Lockett playing so well, teams will have to adjust by paying extra attention to his activities on the field. As a result, the door could be open for Metcalf to benefit. He had 11 targets from Russell Wilson in Week 2, so he certainly hasn't forgotten about him.

 

FanDuel Tight Ends - Week 3 Picks

Travis Kelce, TE - @ LAC ($8,500)

Regardless of what the Chargers plan to do on the defensive end against the Chiefs, there isn't much the club can do to slow down Kelce, who, once again, is the best tight end in football. The veteran is as good as it gets, and he is nearly guaranteed to produce every time he steps on the field.

The 31-year-old is always involved, so much so that he hasn't had less than seven targets since Week 7 of the 2020 season, including the postseason. As expected, Kelce is anticipated to be the most popular option at the position for Week 3, and he could end up as the most rostered DFS option overall as well.

 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Daniel Berger

Making Start in Season Finale at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Keegan Murray

Expected to Make Season Debut Thursday
Gleyber Torres

Accepts Tigers Qualifying Offer
Alexandre Sarr

Uncertain for Wednesday's Game in Minnesota
Ausar Thompson

Returning Versus Atlanta
Cade Cunningham

Active on Tuesday Night
Jabari Smith Jr.

Questionable with Knee Issue Ahead of Meeting Versus Cleveland
Domantas Sabonis

to Miss Wednesday's Game
Paul George

Won't Play Wednesday Night
Onyeka Okongwu

Available on Tuesday
Joel Embiid

Listed as Doubtful for Wednesday
Jalen Suggs

Available Tuesday
Zaccharie Risacher

Ruled Out With Hip Contusion vs. Pistons
Odell Beckham Jr.

Officially Reinstated by NFL Commissioner
Kristaps Porzingis

Ruled Out on Tuesday Night
Buddy Hield

Available for Tuesday's Matchup With Orlando
Matt Murray

to Miss Six Weeks With Lower-Body Injury
Ilya Lyubushkin

Out on Tuesday
Giannis Antetokounmpo

Out 1-2 Weeks With Groin Strain
Jamie Benn

Makes Season Debut Tuesday
Stephon Castle

Sidelined 1-2 Weeks
Evgenii Dadonov

on Track to Return Tuesday
Dougie Hamilton

a Game-Time Call Tuesday
Anthony Cirelli

Expected to Return Against Devils
Victor Hedman

Questionable for Tuesday
LeBron James

Aims to Make Season Debut Tuesday
Auston Matthews

to Miss at Least Two More Games
Grayson Allen

Sidelined on Tuesday
Gabe Vincent

Set to Suit Up Tuesday
C.J. Stroud

Expected to Return in Week 13 Against Colts
C.J. Stroud

to Miss Another Game
Jonathan Kuminga

Remains Out Tuesday
Keegan Murray

Could Make his Season Debut This Week
Caris LeVert

Liston as Out on Tuesday
Joe Mixon

Uncertainty Remains Around Joe Mixon's Return Timeline
Jaylen Warren

Mike Tomlin Optimistic About Jaylen Warren's Availability for Week 12
C.J. Stroud

Not Expected to Play on Thursday Night
Aaron Rodgers

Won't Need Surgery on Fractured Wrist, Could Play in Week 12?
Davis Mills

Prepping for Third Straight Start in Week 12?
CFB

Sam Leavitt Set to Enter Transfer Portal?
Mason Rudolph

Could Make His First Start of 2025 in Week 12
Brock Wright

Sets Career-High in Targets; Lined Up for More Work?
Kimani Vidal

Struggles Again and Faces Role Uncertainty After Bye
Dak Prescott

in Full Command Monday Night With Four Touchdown Passes
Quentin Johnston

Posts Zero Catches During Offensive Collapse
George Pickens

Erupts for 144 Yards, Touchdown in Monday Night Win
CeeDee Lamb

George Pickens Benched for First Drive
Jose Altuve

Undergoes Foot Surgery
Alex Singleton

Broncos Optimistic Patrick Surtain, Alex Singleton Will Return After the Bye
Trey Hendrickson

Doubtful Again in Week 12
Shedeur Sanders

Expected to Make First Career Start in Week 12
Josh Jacobs

Dealing With Knee Contusion
Mikael Granlund

Unavailable Monday
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
Conor Garland

Misses Monday's Game
Eetu Luostarinen

Out on Monday
Drake London

Considered "Week-to-Week"
Drew Doughty

Listed as Week-to-Week
Ja'Marr Chase

Being Suspended for One Game for Unsportsmanlike Conduct
John Carlson

a Game-Time Call Monday
Viktor Arvidsson

Out Week-to-Week
Charlie McAvoy

Out Against Hurricanes
CFB

James Franklin to be Virginia Tech's Next Head Coach
CFB

Fernando Mendoza the Clear Heisman Trophy Favorite?
CFB

Beau Pribula Has Chance to Face Oklahoma on Saturday
Mitchell Marner

Establishes Vegas Record Sunday
Mats Zuccarello

Logs Two Assists in Overtime Victory
Lucas Raymond

Leads Red Wings to Victory at MSG
Quinn Hughes

Delivers Four Assists in Sunday's Win
Conor Garland

Limited to Handful of Minutes Sunday
Ryan Hartman

Suffers Lower-Body Injury
Jack Della Maddalena

Gets Dominated
Islam Makhachev

Claims UFC Welterweight Belt
Zhang Weili

Gets Outclassed
Valentina Shevchenko

Wins Unanimous Decision At UFC 322
Sean Brady

Suffers First-Round TKO Loss
Michael Morales

Remains Unbeaten
Leon Edwards

Suffers Second-Round Knockout Loss
Leon Edwards

Carlos Prates Becomes The First Man To Knock Out Leon Edwards
Beneil Dariush

Suffers Brutal First-Round Knockout Loss
Beneil Dariush

Benoit Saint Denis Knocks Out Beneil Dariush In 16 Seconds
Josh Naylor

Mariners Finalizing Five-Year Contract
CFB

Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
CFB

Virginia Tech Close To Naming James Franklin As Head Coach
CFB

Garrett Nussmeier Doubtful vs. Arkansas On Saturday
Edwin Díaz

Blue Jays Interested in Signing Edwin Diaz?
Jacob deGrom

Named AL Comeback Player of the Year
Ronald Acuña Jr.

Ronald Acuna Jr. Wins NL Comeback Player of the Year Award
Aroldis Chapman

Named AL Reliever of the Year
Edwin Díaz

Edwin Diaz Named NL Reliever of the Year
Justin Thomas

Will Miss Start Of 2026 After Undergoing Back Surgery
Islam Makhachev

Set For UFC 322 Main Event
Jack Della Maddalena

Set For His First Title Defense
Zhang Weili

Can Become The New Women's Flyweight Champion
Valentina Shevchenko

Set For UFC 322 Co-Main Event
Michael Morales

Looks To Remain Undefeated
CFB

Mario Craver a Game-Time Decision for Week 12
Sean Brady

Set For Title Eliminator Bout
Carlos Prates

A Favorite At UFC 322
Leon Edwards

Looks To Get Back In The Win Column
Benoît Saint Denis

Benoit Saint Denis Set To Open Up UFC 322 Main Card
Beneil Dariush

Looks To Win Back-To-Back Fights
CFB

Virginia's Chandler Morris Trending Toward Facing Duke on Saturday
Edwin Díaz

Edwin Diaz Says There's a "50-50" Chance he Returns to Mets
Shohei Ohtani

Wins his Fourth MVP Award
Aaron Judge

Wins AL MVP Award Again
Raisel Iglesias

Dodgers Interested in Signing Raisel Iglesias
Pete Alonso

Orioles Could be in the Mix to Sign Pete Alonso
Félix Bautista

Felix Bautista Could Return in Second Half in 2026
Kodai Senga

Attracting Trade Interest, Will the Mets Move him?
Yordan Alvarez

Expected to be Ready for Spring Training
Byron Buxton

Could Waive his No-Trade Clause

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP