🦃 BLACK FRIDAY - SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

FanDuel NFL DFS Lineup Picks for Week 3 - Daily Fantasy Football

Patrick Mahomes - Fantasy Football Rankings, DFS Lineup Picks, NFL Injury News

Dennis Clausen highlights the top FanDuel NFL DFS lineup picks for Week 3 of the 2021 season, and some value sleepers for your daily fantasy football rosters.

Week 2 is behind us. Still, it's imperative to acknowledge some of the impressive DFS performances, beginning with Tom Brady, who threw five touchdowns against the Atlanta Falcons, while Kyler Murray had another majestic outing, throwing for 400 yards against the Minnesota Vikings. Going down the rest of the list, Derrick Henry and Aaron Jones combined for seven total touchdowns, and at the wideout position, Cooper Kupp totaled 32.3 fantasy points against the Colts, and Tyler Lockett accumulated 178 yards and a touchdown off eight catches against the Tennessee Titans.

Week 3 will begin with a Thursday Night Football showdown between Sam Darnold and the undefeated Carolina Panthers squaring off against the Houston Texans at NRG Stadium. Of course, as we head toward the Sunday slate of contests, there are some injuries to monitor. Dalvin Cook is dealing with a sprained ankle, Josh Jacobs continues to be plagued by a bad toe and ankle, and Saquon Barkley will look to increase his workload after undergoing knee surgery in October. Nonetheless, if any of these guys are out, there will be some value opportunities without a doubt.

In this article, I will be providing you with my Week 3 daily fantasy football lineup picks for FanDuel’s “Main Slate.” These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Feel free to give me a follow on Twitter @DennisMClausen. Also, be sure to check back on Saturday night and Sunday morning for updates heading into Week 2.

Be sure to check all of our fantasy football rankings for 2025:

Article Updated: Saturday, September 25 @10:30 pm

It's late on Saturday night, but a good time to start examining how to attack Week 3. There have been a few updates throughout the day, some that could change the landscape of roster construction for Sunday. Lamar Jackson remains questionable with the stomach bug. However, it would be surprising if he didn't suit against Detroit.

However, Dalvin Cook and Darrell Henderson Jr. appear to be heading in the opposite direction, which will ultimately make guys like Sony Michel and Alexander Mattison see a significant increase in fantasy interest. Still, managers shouldn't be sold that either is a lock to produce, so pivoting off of those two could pay off.

 

FanDuel Quarterbacks - Week 3 Picks

Patrick Mahomes, QB - @ LAC ($8,700)

Mahomes didn't get much recognition after his impressive showing during the overtime loss to Baltimore on Sunday Night Football. Instead, his brother, Jackson, received most of the attention, primarily after he was caught on video pouring water on a heckling Ravens fan. Unfortunately, the viral video overshadowed just how well the Chiefs' signal-caller has played throughout the first few weeks of the 2021 campaign.

Mahomes is playing better than ever this season, averaging 340 passing yards per contest and throwing six touchdowns in total. He also has a quarterback rating of 131.4, which is fantastic, and he only has one erroneous toss to his credit. Of course, as we examine the Week 3 matchups, it doesn't take long to realize that Vegas has Kansas City as the highest-scoring team on the slate. This game is also predicted to run close, which should allow the former MVP plenty of chances to make some noise on the fantasy end.

Kirk Cousins, QB - vs. SEA ($7,700)

Cousins has played as well as anyone could hope. Before the year started, the veteran was in the news. However, it wasn't for a good reason, as many questioned his ability to lead a team. Since then, things have settled down on that front, and Cousins quietly continues to build on to an efficient 2021 season.

The 33-year-old has historically been an accurate passer over the years. Yet, he has improved even more and is currently sitting on a 71.6 completion percentage and a 112.9 passer rating, both career-highs. Cousins' Week 3 opponent, the Seattle Seahawks, hasn't impressed on the defensive end this season either. As a result, he is someone to consider, especially with Dalvin Cook (possibly), Adam Thielen, and Justin Jefferson at his disposal.

Also Consider:

Kyler Murray, QB - vs. Jac ($9,000)

Murray could end up being one of the most rostered options at the position. However, keep in mind that the Cardinals are playing Jacksonville, a team that should get beat up pretty badly. DeAndre Hopkins is also in danger of sitting. Still, Murray can do so much using his legs and is capable of racking up plenty of fantasy points before the game gets out of

Josh Allen, vs. WAS ($8,000)

After getting more than enough attention in DFS columns for Weeks 1 and 2, Allen has been flying under the radar entering Week 3 against the Washington Football Team. Vegas' projections are favorable for the signal-caller, and he has just as good a chance as others to finish as the top quarterback on the slate.

Tom Brady, QB - @ LAR ($7,800)

Rolling with Brady in Week 3 can surely pay off, especially for DFS managers looking to save some cash by avoiding Patrick Mahomes or Kyler Murray. The GOAT will be without Antonio Brown. Yet, he still has Chris Godwin, Mike Evans, and Rob Gronkowski to keep him in the running as one of the most lethal options on the slate.

Matthew Stafford, QB - vs. TB ($7,600)

Stafford arguably has the most talented group of wideouts he has ever had at his disposal. He will also have plenty of opportunities to put up some numbers in a game that should be a shootout.

 

FanDuel Running Backs - Week 3 Picks

Joe Mixon, RB - @ PIT ($6,700)

During Cincinnati's season opener against the Vikings, Mixon carried the pigskin 29 times, resulting in 127 yards and a touchdown to finish out the afternoon. That performance was definitely welcomed by fantasy managers, especially since he missed most of last year because of a foot ailment.

Naturally, many believed Mixon could produce a similar showing in Week 2 against Chicago. He did have 20 touches in that one, which was good. However, he only managed to scrounge together 69 yards on the ground while only catching one of his two targets. Nonetheless, the Bengals will face a familiar foe on Sunday, the Steelers, a team that the former Sooner has encountered many times throughout his career. He has played relatively well against Pittsburgh, too, amassing 5.5 YPC throughout six meetings. He should be a featured piece of the Bengals' offensive approach in Week 3, and after an average performance against Minnesota, his rostering cost took a considerable dip.

Saquon Barkley, RB - vs. ATL ($6,000)

After suffering a season-ending knee injury in 2020, Barkley wasn't a lock to play this early in the year. Yet, after he began the season with some restrictions, he seems to be moving in the right direction.

The former Nittany Lion finished Week 1 against the Denver Broncos by logging just 10 carries. Then, with a Thursday Night Football showdown against Washington just four days later, he touched the ball a few more times. He has been limited at practice throughout the week, but he could see a noticeable bump in snaps, mainly after getting some additional rest. Barkley was once considered the top fantasy back in the league, and with a rostering cost of $6,000, managers should be willing to take a chance on him in Week 3 against Atlanta.

Also Consider:

Derrick Henry, RB - vs. IND ($9,700)

Henry fell off the map in Week 1 but got his revenge in Week 2 by dumping nearly 45 fantasy points on the Seattle Seahawks. Vegas has him finishing with the most rushing yards in Week 3, so that's as good of a reason to keep him in mind, assuming managers are willing to pay nearly $10,000 for his DFS services.

 

FanDuel Wide Receivers - Week 3 Picks

Tyreek Hill, WR - vs. LAC ($8,700)

With Patrick Mahomes expected to lead all quarterbacks in production in Week 3, it is only logical to pair him up with his favorite receiver. This is as good of a stacking opportunity as it can get, mainly with Kansas City potentially putting up a ton of points against the Chargers.

The 27-year-old got off to a fantastic start to the new year. He was targeted 15 times in Week 1, hauling in 11 receptions for nearly 200 yards and a touchdown. Yet, he fizzled against the Baltimore Ravens during Sunday Night Football and only came away with three catches for a miserable 14 yards. Fantasy managers should certainly give Hill a free pass for that performance, as he has a great chance to rebound in Week 3.

Cooper Kupp, WR - vs. TB ($7,900)

Kupp has arguably been the best wideout in the league this season. After Jared Goff was sent to Detroit in exchange for Matthew Stafford, he appears to be meshing quite well with his new signal-caller. He currently ranks first in receptions (16), sixth in targets (21), and third in receiving yards (271).

Although his effectiveness throughout the first two weeks of the year doesn't mean anything in terms of his Week 3 potential, his ceiling remains as high as ever. With the contest against the Tampa Bay Buccaneers foreseen to feature two gunslingers airing it out, Kupp should stay in the conversation as a must-start DFS option in all formats. Managers should consider that he will undoubtedly see a ton of interest, although pivoting here may not be wise.

Also Consider:

Stefon Diggs, WR - vs. WFT ($7,700)

Diggs had just four catches in Week 2 against the Miami Dolphins. However, he's been targeted 21 times by Josh Allen this season, and for the price, managers should be more than eager to get him back in their DFS lineups on Sunday.

DK Metcalf, WR - @ MIN ($7,200)

Metcalf has been overshadowed by the superior play of his teammate, Tyler Lockett, over the last few weeks. With Lockett playing so well, teams will have to adjust by paying extra attention to his activities on the field. As a result, the door could be open for Metcalf to benefit. He had 11 targets from Russell Wilson in Week 2, so he certainly hasn't forgotten about him.

 

FanDuel Tight Ends - Week 3 Picks

Travis Kelce, TE - @ LAC ($8,500)

Regardless of what the Chargers plan to do on the defensive end against the Chiefs, there isn't much the club can do to slow down Kelce, who, once again, is the best tight end in football. The veteran is as good as it gets, and he is nearly guaranteed to produce every time he steps on the field.

The 31-year-old is always involved, so much so that he hasn't had less than seven targets since Week 7 of the 2020 season, including the postseason. As expected, Kelce is anticipated to be the most popular option at the position for Week 3, and he could end up as the most rostered DFS option overall as well.

 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Travis Kelce

Open to Returning in 2026?
Onyeka Okongwu

Could Miss Matchup With Pelicans
Brandon Aiyuk

49ers, Brandon Aiyuk Headed for a Divorce Soon?
D'Angelo Russell

Ruled Out Against Pelicans
Trey Hendrickson

Ruled Out for Week 12
Tre Jones

Cleared to Play Friday with Planned Minutes Limit
Jaden McDaniels

Cleared to Face Phoenix
Coby White

Ruled Out for Friday's Game Against Miami
Jarrett Allen

Ruled Out on Friday
Jaren Jackson Jr.

Doubtful as Grizzlies Face Mavericks
Adolis García

Rangers Non-Tender Adolis Garcia on Friday
Jaylon Tyson

Returning Versus Indiana
Darius Garland

Cleared to Play on Friday, Expected to See Limited Action
Marvin Bagley III

to Miss Friday's Game Against Raptors
Auston Matthews

Doubtful for Saturday
Rashod Bateman

Ruled Out for Week 12
Alexandre Sarr

Ruled Out for a Second Straight Game
Roman Josi

Could Return Saturday
Samuel Honzek

Out for Six Months After Surgery
Chris Godwin

Officially Questionable for Week 12
Sion James

Expected to Play Through Groin Issue Saturday
Jalen Chatfield

Available for Friday's Matchup
Andrew Wiggins

Labeled as "Day-to-Day"
Nico Sturm

Activated From Injured Reserve
Jason Zucker

Available Friday
Brandon Miller

Returning To Charlotte's Lineup On Saturday
Connor Hellebuyck

to Miss 4-6 Weeks
Jaylen Warren

Cleared From Injury Report Ahead of Week 12
Jalen Brunson

Probable For Saturday's Matchup With The Magic
Brian Thomas Jr.

Ruled Out for Week 12
Kenneth Walker III

Listed as Questionable for Week 12
Kyle Filipowski

Good To Go Friday Night
Trey Benson

Ruled Out For Week 12
Shaedon Sharpe

Won't Suit Up Friday
Jrue Holiday

to Miss Fourth Straight Game Friday Night
Josh Jacobs

Officially Questionable to Play in Week 12
Darius Slayton

Cleared to Return From Hamstring Injury in Week 12
Daniel Jones

"Good to Go" for Week 12
Alvin Kamara

Officially Questionable to Play in Week 12
Xavier Worthy

"Trending in the Right Direction," Officially Questionable
Isiah Pacheco

Out Against Colts
Drake London

Officially Ruled Out for Week 12
CFB

Beau Pribula Expected to Start Against Oklahoma
Aaron Rodgers

Questionable to Play Against Bears
Grayson Allen

Sidelined Again on Friday
Jaden McDaniels

Could Miss Another Game on Friday
Cooper Flagg

Listed as Available on Friday
Rhamondre Stevenson

Expected to Return in Week 12
Jayden Reed

Packers Open Jayden Reed's Practice Window on Friday
Chris Godwin

Trending Toward Playing on Sunday
Joe Burrow

Officially Questionable for Week 12
Dan Hooker

An Underdog At UFC Qatar
Arman Tsarukyan

Looks To Extend His Win Streak
Ian Machado Garry

A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
Alonzo Menifield

Looks For His Third Consecutive Win
Volkan Oezdemir

Looks To Get Back In The Win Column
Myktybek Orolbai

Looks To Win Back-To-Back Fights
Jack Hermansson

Makes His Welterweight Debut
Kyoji Horiguchi

Returns To The UFC
Tagir Ulanbekov

Set To Open Up UFC Qatar Main Card
Sergei Bobrovsky

Frustrates Devils With Shutout
Adam Fantilli

Leads Blue Jackets to Victory in Toronto
Ilya Sorokin

Posts Second Shutout of the Season
Alex Ovechkin

Nets 33rd Career Hat Trick
Andre Burakovsky

Ruled Out for Friday
Gavin Brindley

Hurt Versus Rangers
Jake Evans

Exits With Injury Thursday
Elly De La Cruz

Played Through Partially Torn Quad to End 2025
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal
Simon Holmstrom

Ready for Action Thursday
Lars Eller

Available Thursday
Ridly Greig

Out Against Ducks
Jake Neighbours

Back for Blues Thursday
TB

Nicholas Paul Available Thursday
Victor Hedman

Out for "Couple of Weeks"
Tyler Bertuzzi

Set to Return Thursday
Raisel Iglesias

Returning to the Braves on One-Year Deal
Sahith Theegala

Looking to Continue Fall Run at RSM Classic
Stephan Jaeger

Looking to Bounce Back at RSM Classic
Tom Hoge

Looking to Regain Form at RSM Classic
Joe Highsmith

Searching for Turnaround at RSM Classic
Adam Hadwin

Looking to Build on T11 Finish in Bermuda
Austin Eckroat

Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
CFB

Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

Teetering for PGA Tour Card in 2026
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Gleyber Torres

Accepts Tigers Qualifying Offer
CFB

Sam Leavitt Set to Enter Transfer Portal?
Jose Altuve

Undergoes Foot Surgery
Alex Bregman

Red Sox Going for Either Alex Bregman or Pete Alonso?
CFB

James Franklin to be Virginia Tech's Next Head Coach
CFB

Fernando Mendoza the Clear Heisman Trophy Favorite?
CFB

Beau Pribula Has Chance to Face Oklahoma on Saturday
Jack Della Maddalena

Gets Dominated
Islam Makhachev

Claims UFC Welterweight Belt
Zhang Weili

Gets Outclassed
Valentina Shevchenko

Wins Unanimous Decision At UFC 322
Sean Brady

Suffers First-Round TKO Loss
Michael Morales

Remains Unbeaten
Leon Edwards

Suffers Second-Round Knockout Loss
Leon Edwards

Carlos Prates Becomes The First Man To Knock Out Leon Edwards
Beneil Dariush

Suffers Brutal First-Round Knockout Loss
Beneil Dariush

Benoit Saint Denis Knocks Out Beneil Dariush In 16 Seconds
Josh Naylor

Mariners Finalizing Five-Year Contract
CFB

Jeremiah Smith, Carnell Tate Not Dealing With Long-Term Injuries
CFB

Virginia Tech Close To Naming James Franklin As Head Coach

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP