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FanDuel MLB DFS Lineup Picks (9/17/21): Daily Fantasy Baseball Advice

Zack Wheeler - Fantasy Baseball Rankings, Draft Sleepers, MLB Injury nNews

Juan Carlos Blanco highlights the top FanDuel MLB DFS lineup picks for 9/17/21, and a couple of sleepers to consider while building daily rosters.

We're set up with a full Friday night slate, as there are no day games at all this week. There's a strong array of pitching near the top end of the salary scale as well, and although limited pitch counts for hurlers on contending teams do rear their head at times during this part of the season, we have a few arms today we should be able to trust will have a chance at a solid workload

We also have quite a few value options as far as pitchers are concerned, making it possible to put together a strong lineup with several sub-$3K plays and some superstars that will require heftier investment.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel main slate on 9/17/2021. Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also read more DFS advice and lineup picks for sites like DraftKings, and other sports.

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FanDuel DFS Pitchers

Cash Game/GPP Anchor Play:

Zack Wheeler – at NYM ($10,700)

Wheeler has been lights out against his former squad this season, pitching to a 2-1 record, 2.15 ERA and 31:5 K:BB across three starts versus New York. The right-hander has given up a bit more on the road overall, but he actually sports a lower HR/9 when traveling (0.5) than at home (0.9). Wheeler has averaged 40.8 FD points on the season, and he'll check into Friday night's contest with back-to-back 50-plus FD-point tallies. The Mets have been relatively tough on visiting righties in the last month (.335 wOBA), but current New York bats have just a collective .143/.164/.373 slash line against Wheeler over 39 career encounters.

Potential Alternate Play

Logan Webb– vs. ATL ($9,500)    

Webb has developed into one of the most dependable components of the Giants rotation this season, and he just recent scored between 40 and 52 FD points in seven straight starts before managing a solid 27 in his most recent start against the Cubs at Wrigley. The hard-throwing right-hander has been outstanding at home, however, pitching to a 5-0 mark, 1.66 ERA, 0.96 WHIP, 10.4 K/9 and 0.7 HR/9 over 54.1 innings. He also blanked the Braves over seven innings in his one previous start against them this season, and Atlanta hasn't been particularly threatening to righties on the road over the last month with a .235 average, .291 OBP and .317 wOBA. Finally, consider current Braves bats own just a collective .152/.201/.152 slash line against Webb with zero extra-base hits and 11 strikeouts in 42 career encounters.

ALSO CONSIDER: Walker Buehler - at CIN ($9,900)

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FanDuel DFS Infielders

Eric Hosmer- 1B, at STL ($2,600)

Hosmer certainly shouldn't be rostered at a very high rate on a full Friday night slate, but he's an intriguing pivot for tournaments for a couple reasons Friday. The first is the matchup against Cardinals starter Miles Mikolas, who's allowed a .308 average and .359 wOBA to the 61 left-handed hitters he's faced thus far this season, and a .287 average and 12 homers in that split since the start of the 2019 campaign. Then, consider Hosmer sports a solid .329 wOBA against right-handed pitching on the road, along with a modest 16.4 percent strikeout rate and .354 OBP in that split. Finally, there's a prior body of work at play here also, as Hosmer has tagged Mikolas for a .444 average with a double and a home run in nine career encounters.

David Fletcher – 2B, vs. OAK ($2,600)

Fletcher's handiwork this season against left-handed pitching includes a .355 average and .380 OBP versus that handedness at home. The infielder hasn't been anywhere near as productive in the second half of the season as he was during a torrid All-Star-break portion of the campaign, but Fletcher is still a reliable contact hitter that also has a solid matchup against a visiting southpaw in Cole Irvin. Irvin has allowed a .281 average and .330 wOBA to right-handed hitters on the road, and a .296 average and .343 wOBA in the second half of the campaign. What's more, Fletcher has given him trouble in the past in the form of a .556 average with two doubles and zero strikeouts over 11 previous career encounters.

Justin Turner – 3B, at CIN ($3.700)

Turner has actually been a better performer on the road this season, where he sports a .295 average and .900 OPS overall, and a .382 wOBA and 144 wRC+ when facing right-handers outside Dodger Stadium. The veteran has recently snapped out of a multi-game funk with a .438 average over his last four contests, a span during which he's quickly amassed two homers and seven RBI. He'll have a shot at Luis Castillo on Friday, with the Reds right-hander having surrendered 12 of his 18 home runs on the season in same-handed matchups and having pitched to a .327 wOBA since the All-Star break.

Xander Bogaerts – SS, vs. BAL ($3,700)

Bogaerts is always under consideration against a left-hander and especially at Fenway. The veteran shortstop is enjoying another stellar campaign and has punished southpaws for a .419 wOBA and .260 ISO against left-handed pitching at home.  He also has a .333 average and .434 wOBA in 24 September plate appearances, sending him into Friday's matchup with a hot bat. Meanwhile, Orioles left-hander Keegan Akin makes for a great target as well, as he's pitched to a 7.60 ERA, 1.73 WHIP and 2.2 HR/9 when traveling, and he's allowed a .310 average and .397 wOBA to right-handed hitters specifically on the road.

 

FanDuel DFS Outfielders

George Springer - vs. MIN ($3,900)

Springer has hit safely in five of his last six games and tagged right-handed pitching for a .907 OPS overall. He's also boasting a 1.044 OPS and .310 average in his hitter-friendly home parks this season, and he's battered right-handed pitching there for a .427 wOBA and .350 ISO there. All of those figures put him firmly in play against right-hander Michael Pineda on Friday. The veteran has been adequate this season, but he's allowed a .260 average and seven homers to right-handed hitters, and he just yielded a .327 average and .369 wOBA in August, a reminder of his vulnerability. Additionally, the gulf between his 3.11 FIP and 4.64 xFIP against right-handed hitters on the road hints at some good fortune that could run out against a hitter like Springer, who's also pounded Pineda for a .455 average with three doubles and three homers in 23 career encounters.

Bryan De La Cruz– vs. PIT ($3,300)  

De La Cruz makes for an excellent right-handed bat to trot out against Pirates starter Wil Crowe, who's allowed a 7.04 ERA and 1.70 WHIP on the road, and who's given up a .327 average, 2.9 HR/9 and .417 wOBA to righty bats in that split. Meanwhile, De La Cruz has enjoyed an excellent rookie season and thrived in same-handed matchups, posting a .333 average and .836 OPS versus righties, along with a .360 wOBA. He's also been elite at LoanDepot Park, as evidenced by his .365 average and .891 OPS in his home field.

Dylan Carlson – vs. SDP ($2,700)

The switch-hitting Carlson makes for a viable value consideration for tournaments against the debuting Vince Velasquez, who's surrendered a .299 average and .391 wOBA to left-handed hitters. Carlson boasts a .298 average at home, and he's belted 10 of his 13 homers this season when hitting from the left side against righty arms. Moreover, although his average is much better against southpaws, Carlson has been a solid performer versus right-handed pitching at Busch Stadium, where he sports a .270 average, .346 OBP and .327 wOBA in that split.



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More DFS Lineup Picks and Analysis




REAL-TIME FANTASY NEWS

OG Anunoby

is Downgraded to Out for Game 3 on Friday
Mitchell Robinson

is Returning for Game 3
Mats Zuccarello

Expected to Play Saturday
Joel Eriksson Ek

to Be a Game-Time Decision Saturday
Jonas Brodin

Still Out Saturday
Josh Manson

Could Return Saturday
Kaedan Korczak

Scratched for Game 3 Against Ducks
Radko Gudas

Likely to Remain Out Friday
Sam Carrick

Won't Play Friday
Isiah Pacheco

Can Isiah Pacheco Re-Establish His Dynasty Value in Detroit?
Rico Dowdle

Dynasty Ceiling Limited By Backfield Committee in Pittsburgh
Rashid Shaheed

a High-Risk, High-Reward Buy-Low Candidate for Dynasty Managers
Marcus Mariota

Is Marcus Mariota Worth Stashing as an Injury Replacement in Dynasty Leagues?
Jacoby Brissett

a Clear Sell-High Candidate for Dynasty Managers
Blake Snell

to Make Season Debut for Dodgers on Saturday
Najee Harris

Can Najee Harris Re-Establish Some Dynasty Value in 2026?
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Breece Hall

Jets Sign Breece Hall to Three-Year Extension Worth $45.75 Million
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
Denver Broncos

Broncos Sign GM George Paton to New Five-Year Deal
Brandon McManus

Packers Release Kicker Brandon McManus
New York Jets

Jets Talking to a "Number of Veteran Quarterbacks"
Travis Etienne Jr.

a Reliable Dynasty Starter Entering First Season With Saints
Kenneth Gainwell

Is Kenneth Gainwell's Dynasty Stock Still Rising After Offseason Change of Scenery?
Mac Jones

a Deep-League Dynasty Stash Candidate
Tez Johnson

Facing Uphill Battle for Playing Time in Tampa Bay
Jared Goff

Remains a High-Floor Dynasty QB2 Heading into 2026
De'Von Achane

Remains a High-End Dynasty RB Despite Uncertain Supporting Cast
Xavier Worthy

Chiefs Limited Xavier Worthy's Usage After Injury Last Year
Rashee Rice

Chiefs Not Ready to Discuss Extension With Rashee Rice?
Cade Otton

Remains a Quality Dynasty Depth Piece
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
Austin Reaves

Scores 31 Points in Game 2 Defeat
T.J. Hockenson

Bounce-Back Chances Stifled by Improved Pass-Catching Depth
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
Chet Holmgren

Anchors Thunder Past Lakers in Game 2
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
Jordan Addison

Facing Competition for No. 2 Role?
Tobias Harris

Stays Hot in Game 2 Victory
Cade Cunningham

Pushes Pistons to 2-0 Series Lead
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
Jarrett Allen

Provides Bright Spot in Cavs' Game 2 Loss to Pistons
CFB

Rasheem Biles an Instant Impact Player for Texas
James Harden

Struggles in Game 2 Loss
Donovan Mitchell

Finishes Game 2 Loss with 31 Points
Gradey Dick

Open to Trade Away From Toronto
Michael Porter Jr.

Wants to Stay in Brooklyn
Charlotte Hornets

Hornets Extend Charles Lee After 25-Win Improvement
Jarred Vanderbilt

Ruled Out for Game 2 Against Thunder
Luke Kennard

Cleared to Play Thursday
Ayo Dosunmu

Considered Questionable for Game 3 Against Spurs
Anthony Edwards

Remains Questionable on Injury Report Ahead of Game 3
Mitchell Robinson

Probable for Friday's Action
Kevin Huerter

Remains Out Thursday
Sam Merrill

Unavailable Thursday
OG Anunoby

Tagged as Questionable for Friday
Joel Embiid

Listed as Questionable for Game 3 Against Knicks
Dan Vladar

Looks to Return to Winning Ways Thursday
Connor Dewar

Penguins Re-Sign Connor Dewar for Two Years
Mikko Rantanen

Played Through Torn MCL Late in the Season
Rasmus Dahlin

Ready to Go Friday
Alexander Nikishin

Set to Return Thursday
Christian Dvorak

Available Thursday
Owen Tippett

Remains Out Thursday
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Mark Stone

Nets Late Power-Play Goal in Losing Effort
Leo Carlsson

Pots Game-Winner Wednesday Night
Juraj Slafkovsky

Ends Point Drought in Game 1 Loss
Bowen Byram

Ties Franchise Record With Fourth Postseason Goal
Zach Benson

Posts Second Consecutive Multi-Point Game
Rasmus Dahlin

"Seems Fine" After Early Exit on Wednesday
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Nils Hoglander

Will Miss World Championship Due to Injury
Framber Valdez

Suspended Six Games
Tyler Glasnow

Exits Early on Wednesday With Back Pain
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Brandon Woodruff

has Fluid Drained From his Right Shoulder
Brandon Woodruff

to Resume Throwing on Saturday, Return Imminent?
Carlos Correa

to Have Season-Ending Ankle Surgery
Jacob Misiorowski

Listed as Friday's Probable Starter
Logan Webb

Dealing With Knee Discomfort
Carlos Correa

Expected to Miss Significant Time With Ankle Injury
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Emilio Pagán

Emilio Pagan Headed for Injured List With Hamstring Injury
Emilio Pagán

Emilio Pagan Carted Off With Apparent Hamstring Injury on Tuesday
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
MLB

Cardinals-Brewers Game Postponed on Tuesday
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Tim Elliott

Drops Decision At UFC Perth
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
William Byron

Might have the Speed to Compete for the Win at Texas
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Tyler Reddick

One of the Favorites to Win at Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF