👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

EPL DFS Lineup Picks for FanDuel (4/22/21) - English Premier League Soccer

Vince's FanDuel EPL DFS lineup picks for English Premier League soccer on 4/22/21. His top daily fantasy soccer forwards, midfielders, defenders, goalkeepers.

Welcome back, RotoBallers! If you missed single-game slates after Wednesday's two-gamer, don't worry because there's just one EPL game Thursday and one Friday. That means two straight single-game DFS slates before the weekend. I will be breaking down that game in full for you here. Keep reading this breakdown for my DFS soccer picks on RotoBaller and see how to have success on Thursday's slate.

The very large majority of my DFS content will be EPL or UCL-related, however, there is more soccer than just what is being played in England. If you want to chop it up with myself and other RotoBaller writers about non-EPL leagues or other sports, consider becoming a premium member and joining our ever-growing community of DFS and fantasy sports enthusiasts! There was some great conversation over the four UCL slates we had this week, and the Premium Slack chat is as full as ever!

In this article, I will be providing you with my English Premier League daily fantasy soccer lineup picks for FanDuel on 4/22/21 for the slate that locks at 3:00 pm ET. Be sure to also check out our other DFS lineup picks for other active sports. You can always find me on Twitter @vdray5 if you have any questions. Good luck, RotoBallers!

 

EPL DFS Lineup Picks - Overview

Leicester vs West Brom

Not long ago, Leicester (-175) was looking really good to secure a UCL spot for next year. Now they've lost two straight games and only sit one point ahead of Chelsea in 3rd place - but they do have a one in hand that they'll get back here. West Brom have shown some life with two consecutive wins in which they scored eight and only conceded two. They still have some heavy lifting to do if they want to return to the Premier League next season though. West Brom will likely be overmatched in this game against a good Leicester team at home. The goal total over/under is 2.5.

 

FanDuel DFS Forwards / Midfielders

So many people are liking going to see Jamie Vardy ($15) - a prolific goalscorer - in this prime matchup at home and plug him right into the captain spot without looking back. It's definitely not a bad strategy to get Vardy though. His -140 anytime scoring odds are best on the slate, and he can punish WBU's defense. They're giving up an average of 1.9 goals per game this year overall and still give up 1.73 per game on the road. The big downside with Vardy is his form with just one league goal since Christmas, and his price remains at the maximum. This especially looks bad when you can get Kelechi Iheanacho ($14) for a dollar less who has the same great matchup and has seven goals in his last five EPL games. I recommend one of them in the captain spot, and if you can somehow work it to get both, you give yourself a very high ceiling.

James Maddison ($13) is another top-tier play for Leicester in this matchup. They should roll West Brom in this game. Maddison has the best floor out of Leicester's top three with his chances created and SOGs, and he has solid goal upside at +200. Youri Tielemans ($9) is a strong candidate for a third Leicester attacker. The matchup is good enough for three Leicester attackers, and I highly recommend getting three. You can jam in a fourth Leicester attacker - Marc Albrighton ($7) - and ride a full 4/1 Leicester stack.

West Brom has been scoring more recently than any other time in the season. They draw a far more difficult matchup in this game on the road against Leicester. West Brom only average 1.07 goals per game on the road. Matheus Pereira ($14) is the best WBU attacking option if you want to choose one, but he's very expensive which will essentially take him out of my player pool. Callum Robinson ($11) is much more economical, and Okay Yokuslu ($7) is the deep value guy on the slate with his ability to get peripherals.

 

FanDuel DFS Defenders

The defenders on this slate are not great. None are in particularly good form, the wingbacks with attacking upside are not strong, and neither team allow many defensive peripherals.

Dara O'Shea ($5) immediately hits my player pool as the cheapest expected starter on the slate. Leicester allow the least clearances in the league, but they do force a decent amount of tackles and interceptions. O'Shea can still collect those two stats at a good rate. If he adds in a few clearances or other stats, he'll be well worth $5.

Caglar Soyuncu ($6) is another one of my preferred DEF plays. West Brom allow a good number of clearances (6th most in the league). Soyuncu should fare well with how he can accumulate clearances during a game. Plus, West Brom allow interceptions and tackles at a decent rate. Soyuncu has a strong floor and a good ceiling for a cheap price tag. Not to mention that a clean sheet bonus is a decent possibility too.

 

Thanks for reading my EPL DFS lineup picks breakdown on RotoBaller and good luck!

More DFS Analysis & Lineup Picks

POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Brent Rooker

Exits Early on Thursday Due to Apparent Injury
NFL

No New Injury Issues for Francis Mauigoa
Travis Hunter

to be "Limited Participant" During Offseason Workouts
Carolina Panthers

Denzel Boston Visiting With Panthers on Thursday
Mark Andrews

Ready for More Opportunities in 2026
Tyrone Tracy Jr.

Part of a Muddled Giants Backfield Heading into 2026
Chimere Dike

Fantasy Value Potentially Limited by What He Offers in Return Game
Chase Brown

an Important Name to Monitor on Day 1 of the NFL Draft
Bijan Robinson

Could Just Be Entering His Prime
Jameson Williams

Consistency the Key to a True Jameson Williams Breakout
Jarace Walker

May Exit Pacers Lineup Again Thursday
Aaron Nesmith

Out for Sixth Consecutive Game
T.J. McConnell

Andrew Nembhard, T.J. McConnell Unavailable Thursday
Dru Smith

Iffy for Thursday
Norman Powell

Questionable Thursday
Sam Hauser

Could Miss Thursday's Game
Neemias Queta

Uncertain for Thursday
Zach Benson

Scores Twice in Comeback Victory
Logan Thompson

Shuts Out the Leafs
Zach Eflin

Undergoes Successful Elbow Surgery, Will Miss Remainder of 2026
Derrick White

Listed as Questionable for Thursday
Tre Johnson

Iffy for Thursday
Jaylen Brown

Iffy to Face Knicks
Bilal Coulibaly

Questionable Against Bulls
Gui Santos

Could Miss Another Game Thursday
Alexandre Sarr

Out Again Thursday
Al Horford

to Remain Out Thursday
Caleb Martin

Remains Sidelined Wednesday
Kristaps Porzingis

Unavailable Against Lakers
Klay Thompson

Ruled Out Wednesday
Stephen Curry

Questionable for Thursday Night
Brandon Williams

to Miss Back-To-Back with Illness
LeBron James

Ready to Return Thursday
Daniel Gafford

Ruled Out Vs. Phoenix
J.K. Dobbins

Broncos Prioritized Re-Signing J.K. Dobbins
NFL

Francis Mauigoa to Undergo Additional Imaging on a Back Issue
Kaleb McGary

Retires After Seven Years in the NFL
Jawaan Taylor

Signs with the Falcons
Andrei Kuzmenko

to Be Re-Evaluated in 7-8 Days
Mason Appleton

Won't Play Thursday
Tony DeAngelo

Expected to Return Thursday
John Klingberg

Rejoins Sharks Lineup Wednesday
Alex Lyon

Dealing With Lower-Body Injury
Oliver Ekman-Larsson

Back in Action Wednesday
Alex Ovechkin

Won't Decide Future Until Offseason
Cole Ragans

"Should be Good" for Next Start
Reynaldo López

Reynaldo Lopez Handed Seven-Game Suspension
Jorge Soler

Suspended Seven Games, Will Appeal
NFL

NFL Scouts See Plenty of Upside With Drew Allar
NFL

Ty Simpson to Fall into Second Round in NFL Draft?
Cleveland Browns

Todd Monken "Fired Up" About Quarterback Competition
Cleveland Browns

KC Concepcion Visiting With the Browns
Cole Ragans

Diagnosed With Thumb Contusion
Houston Texans

Texans Pick Up Will Anderson's Fifth-Year Option
C.J. Stroud

Texans Exercise C.J. Stroud's Fifth-Year Option
Cole Ragans

Leaves Early on Wednesday After Being Hit in the Hand
Jacob deGrom

Expects to Make his Next Start
Konnor Griffin

Pirates Sign Konnor Griffin to Nine-Year Extension
Parker Washington

Undervalued Despite League-Winning Finish in 2025
Nico Collins

Is Nico Collins Still a Dynasty WR1?
Justus Annunen

Ends Predators' 120-Game Streak Without a Shutout
Trevor Zegras

Leads Flyers to Victory Tuesday
Kevin Bahl

Sustains Lower-Body Injury Against Stars
Michael Rasmussen

Likely to Miss Rest of Regular Season
Dmitry Kulikov

Done for the Season After Breaking Finger
Jalen Chatfield

Exits Early With Lower-Body Injury
Nazem Kadri

Suffers Upper-Body Injury Tuesday
Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Morgan Geekie

Collects Second Career Hat Trick
Joel Eriksson Ek

has Three Points in Victory
Jacob deGrom

Doesn't Have Structural Damage in his Knee
J.T. Realmuto

Leaves Game on Tuesday Due to Bruised Right Foot
Cody Ponce

to Have Knee Surgery, Expected to Miss Six Months
Alejandro Kirk

Facing Six-Week Absence
Jacob deGrom

to Undergo MRI on Tuesday
Mike Trout

Back in the Lineup on Tuesday
Hunter Brown

Diagnosed with Grade 2 Shoulder Strain
Pavel Mintyukov

Returns From Three-Game Absence
Cutter Gauthier

Remains Sidelined Tuesday
Kirby Dach

Ready to Return Tuesday
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Cade Horton

to Undergo Season-Ending Elbow Surgery
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Jacob deGrom

Pitches Through Knee Issue on Monday
Dalton Rushing

Smacks Two Homers in Rout of Blue Jays
Max Scherzer

Dealing With Forearm Tendinitis, Expected to Make his Next Start
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Mike Trout

Held Out of Series Opener Against Braves
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF