Tom Vecchio's DraftKings analysis and advice. The top NFL DFS lineup picks on for Week 6, as well as a couple of sleepers for daily fantasy football rosters.

RotoBallers, welcome to Week 6 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 6 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 6!

• 2025 fantasy football rankings
• Running back (RB) rankings
• Wide receiver (WR) rankings
• Quarterback (QB) rankings
• Tight end (TE) rankings
• Defense (D/ST) rankings
• Kicker (K) rankings
• FLEX rankings
• Dynasty rankings

Quarterbacks - DraftKings Daily Fantasy Football Lineup Starts

Philip Rivers - LAC @ OAK (DK $6,600)

Rivers is a player you may not feel super comfortable with rostering, but he has been proving people wrong lately. Rivers has 20 or more DraftKings points in three of his last four weeks, and now finds himself in a divisional game vs Oakland, who has the 20th DVOA against the pass. This puts Rivers in a good spot to continue his 20 point trend. This game doesn't have an over under or a spread set due to the Derek Carr injury status, but if this is anything like a normal Chargers vs Raiders game, we should be in for plenty of points. Rivers is good in any format this week, and should strongly consider pairing him with one of his top receivers.

Carson Palmer - ARI vs TAM (DK $6,100)

Palmer is a point of much debate this fantasy season, as he is seemingly on the brink of being obsolete. Palmer has thrown for 290 yards or more in four straight games, and 19 or more DraftKings points in three of four. He is hitting value from a cash game perspective, and pairing him with someone like Larry Fitzgerald is a great idea this week. The Cardinals are 2.5 underdogs at home vs the Buccaneers, who have had their struggles on defense, as they have the 27th DVOA against the pass and 22nd DVOA overall. Not many people may look at Palmer as a top option this week, which makes him a good GPP option.

Running Backs - DraftKings Daily Fantasy Football Lineup Starts

Leonard Fournette - JAX vs LAR (DK $8,000)

Fournette is making his case for rookie of the year so far, and has seen 24 or more rushing attempts in the past two weeks. He has so much volume coming his way every game, he makes a great cash game play. The number of touches is fantastic, and a solid match up in front of him this week. He is at home against the Rams, who have the 18th DVOA against the rush. We have seen the Jaguars shift away from the passing game, and make Bortles more of a game manager. This puts Fournette in a spot to be a workhorse back week in and week out.

Duke Johnson Jr. - CLE @ HOU (DK $5,100)

Johnson has touchdowns in three straight weeks, which is good for 17 or more DraftKings points over that span. The Browns are 9.5 point underdogs at the Texans this week, and with the game script predicting that, Johnson should see plenty of work out of the backfield via the passing game. He has 20 targets over the past three weeks, and on a site like DraftKings, where you get full PPR, for his price, that kind of volume has massive upside. He makes a great flex option, and has plenty of tournament upside.

Wide Receivers - DraftKings Daily Fantasy Football Lineup Starts

Mike Evans - TAM @ ARI (DK $6,900)

Evans is $1K cheaper than he was last week, and despite his tough match up, he is worth a roster spot. He will likely be shadowed by Cardinals corner back Patrick Peterson, but has shown upside in this situation before. In Week 2, he was shadowed when playing in Minnesota, and still finished with seven catches on 12 targets for 13 DraftKings points. Evans is becoming similar to AJ Green, in the aspect that he is almost match up proof. For a receiver that is going to see double digit targets, $6.9K is way too cheap, and plenty of time to reach value.

Keenan Allen - LAC @ OAK (DK $7,900)

If you like a lot of targets when it comes to picking a receiver, look at Allen this week. He has seen double digit targets in four of the fives games this season, and he is up against the Raiders, who have the 31st DVOA against WR1. This puts him in an absolute smash spot, and reaching 20 points on DraftKings shouldn't be tough. He makes a great stack with Rivers, who I mentioned above, and they are good for any format. Consistency and volume is key for a receiver, and Allen is a perfect example of that.

Tight Ends - DraftKings Daily Fantasy Football Lineup Starts

Coby Fleener - NO vs DET (DK $3,200)

Fleener, one of the most tilting players in DFS. He seems to disappoint time and time again, but his match up is simply too good this week to pass up, especially if you are rolling out multiple lineups, have some exposure to him. This game has a 50.5 over under, and Fleener is up against the Lions who have the 28th DVOA against tight ends. His price, his match up, and the game projection are simply all going in his favor, there is no possible way he disappoints again, can he?

Defense - DraftKings Daily Fantasy Football Lineup Start

Kansas City Chiefs vs Pittsburgh Steelers (DK $3,200)

Whenever the Chiefs are at home, they are generally a good option, and they are going up against a struggling Steelers offense. The Chiefs have put up 10 or more DraftKings points in three of the last four weeks. They also have 11 sacks over the last four games, so plenty of point potential from them. Good in any format.

More Week 6 Lineup Prep