X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

DraftKings Daily Fantasy Football Lineup Picks (Week 16): NFL DFS Advice

RotoBallers, welcome to Week 16 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 16 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 16!

 

DraftKings Quarterbacks - Week 16 DFS Picks

Matthew Stafford - DET @ CIN (DK - $6,200)

Stafford is looking like one of the better options at quarterback this week for a number of reasons. First off, the Lions still have something to play for, so he will be doing all he can to get the win. We know he has multi touchdown upside, as he has done nine times this season. Stafford has put up 17 or more DraftKings points in seven of his last nine games, and has shown to be super consistent. He makes a great play in any format this week, as he is up against the Bengals who have the 18th DVOA against the pass.

Cam Newton - CAR vs TB (DK - $6,800)

Newton has scored 15 or more DraftKings points in six straight games, and is up against one of the worst defenses in the league. He is playing the Buccaneers, who have the 29th DVOA against the pass, and the 21st DVOA against the run. This is a prime spot for him, and he has shown his rushing upside in recent weeks. He has 50 or more rushing yards in five of his last six games, bringing plenty of tournament upside with him.

 

DraftKings Running Backs - Week 16 DFS Picks

Kenyan Drake - MIA @ KC (DK - $7,100)

Drake is up against the Chiefs, who have the 31st DVOA against the run, putting him in a great spot this week. Over the past four week, Drake has 80% of the Dolphins rushing attempts, which means he is their lead back and will be in the game regardless of the situation. The game script isn't saying they will be in this game, as they are a 10 point underdog, but if they want a shot in this game, they will run the ball a lot and slow the game down, putting Drake in a spot to succeed.

Christian McCaffrey - CAR vs TB (DK - $6,400)

McCaffrey brings a dual threat out of the backfield, as he has seen 22 targets over his last four games. He isn't a pure running back and has only gone for a season high of 66 yards this season, but saw double digit rushing attempts last week for the first time since Week 9. This is an encouraging sign, which should benefit him this week, since his opponent has a very bad defense. He is up against the Buccaneers, who have the 21st DOVA against the pass, and the 23rd DVOA against running backs in the passing game. Prime match up for him, and the Panthers are still in a spot where they need to win games, so they won't easy off the gas.

 

DraftKings Wide Receivers - Week 16 DFS Picks

Robert Woods - LAR @ TEN (DK - $6,500)

Woods is back from his injury, and last week he put six receptions 45 yards, and one touchdown. He is good mid range option who has some PPR upside against a Titans team who has the 24th DVOA against the pass. This puts him in a good spot, since the Rams still have something to play for, and will not be resting their starters. Woods has multi touchdown upside, which he has shown in the games before his injury.

Chris Godwin - TB @ CAR (DK - $3,000)

With DeSean Jackson being out of practice yet again on Thursday, Godwin is in a spot to see increased targets, as he did last week, after Jackson left the game early with the injury. Last week he ended with five receptions for 68 yards, for a total of 11.8 DraftKings points. He is also super cheap on DraftKings, so the savings he brings to your lineup will allow you to get up to the higher priced players.

 

DraftKings Tight End - Week 16 DFS Pick

Eric Ebron - DET @ CIN (DK - $3,700)

Everyone and their mother is talking about Antonio Gates this week as a tight end option, since he is so cheap, and will be seeing more targets now that Hunter Henry is done for the year. If you want another option at tight end, look at Ebron. he is up against the Bengals who have the 30th DVOA vs tight ends, and have suffered major losses on their defense. He has 15 receptions over his last two games, and with the Lions needing to win games to stay in the playoff picture, he will see plenty of snaps.

 

DraftKings Defense - Week 16 DFS Pick

Detroit Lions @ Cincinnati Bengals

The Lions are in a spot where they need to win games to try and make the playoffs, so look to their defense to step up against a weak Bengals team. Last week against the Vikings we saw that the Bengals have all but given up on the season, making them a nice target this week. The Lions have seven sacks over their last four games, along with five interceptions in that span. They have turnover potential against this weak Bengals offense.

 

More Weekly DFS Analysis





REAL-TIME FANTASY NEWS

Stuart Skinner

Starting Game 1 Against Flyers
Alexandre Carrier

Back at Practice
Jared McCann

Undergoes Lower-Body Procedure
Andrei Kuzmenko

Activated From Injured Reserve
Victor Hedman

Out for Game 1 on Sunday
William Karlsson

Unavailable for Start of First-Round Series
Quinn Hughes

Available Saturday
Miro Heiskanen

Cleared for Game 1
Jonathon Brooks

Buy Window is Still Open for Jonathon Brooks
NFL

Skyler Bell Projects More as an NFL Contributor Than Fantasy Difference-Maker
NFL

Can Chris Brazzell II Find More NFL Success Than Past Tennessee Receivers?
Quinshon Judkins

Brings High Floor but Low Ceiling into Second Season
George Kittle

Has Become a High-Risk Bargain
NFL

Eric McAlister's Dynasty Value in Question Coming Off Pre-Draft Injury
Jhoan Duran

Placed on 15-Day Injured List With Oblique Strain
Brian Thomas Jr.

Can Brian Thomas Jr. Rebound After Down Year in 2025?
Patrick Mahomes

Dynasty Value in Question After Injury?
Tre' Harris

Offers Buy-Low Upside for Dynasty Managers
Braelon Allen

Still Offers Dynasty Upside Despite Lost Season in 2025
Kyle Stowers

Will be Activated on Sunday
Aaron Rodgers

Remains a Free Agent Ahead of the NFL Draft
Josh Allen

Healthy and Armed with New Top Receiver
Kyler Murray

a Zero-Risk Dynasty Target?
Rachaad White

Is Rachaad White an Offseason Trade Target in Dynasty Leagues?
Jesper Wallstedt

to Start in Goal for Minnesota on Saturday
Stefon Diggs

Still a Free Agent Ahead of the NFL Draft
Trey Benson

Stuck in a Crowded Backfield
Jacory Croskey-Merritt

Year 2 Value Tied to Pick No. 7 in the NFL Draft
Sean Tucker

Dynasty Value Still Comes Primarily as an Injury Replacement
Jake Tonges

a Capable Fill-in for as Long as He Needs to Be
NFL

Ja'Kobi Lane Could Need Time to Develop for Fantasy Managers
Chig Okonkwo

Could Still Be Undervalued Despite Calls for a Breakout
LaMelo Ball

Scores 23 Points in Season-Ending Loss
Jordan Goodwin

Fills Stat Sheet in Play-In Win
Paolo Banchero

Powers Magic Into Playoffs
Jalen Green

Drops 36 Points to Clinch Playoff Spot
Amen Thompson

Off Injury Report for Playoff Opener
Jabari Smith Jr.

Cleared After Resting in Season Finale
Alperen Sengün

Alperen Sengun Cleared for Game 1 Against Lakers
Logan Stankoven

Presumed Ready for Game 1
Max Muncy

has Another Multi-Homer Game at Coors Field
Lourdes Gurriel Jr.

Expected to Make Season Debut on Saturday
Austin Riley

Hits Two Home Runs in Shutout Win Over Phillies
Daulton Varsho

Removed Early on Friday With Knee Discomfort
Aaron Gordon

Available for Game 1 Against Timberwolves
Julius Randle

Cleared for Playoffs
Jaxson Hayes

Available Saturday Night
Grayson Allen

Will Play Against Warriors
Kristaps Porzingis

Cleared for Friday's Game
Kevin Durant

Iffy for Saturday's Game 1
Mark Williams

Won't Play Friday Night
Spencer Jones

is Questionable for Game 1 on Saturday
Peyton Watson

is Ruled Out for Game 1 on Saturday
Edwin Uceta

Having More Shoulder Issues, "Shut Down for a Few Days"
Moussa Diabaté

Moussa Diabate is Available on Friday
Ayo Dosunmu

is Available for Saturday's Game
Anthony Edwards

Questionable for Saturday's Action
Jonathan Isaac

Remains Out Friday
Jarrett Allen

Removed From Injury Report Ahead of Playoffs
Josh Hader

Moved to 60-Day Injured List
Willson Contreras

Returns to Red Sox Lineup on Friday
Daniel Palencia

Goes on 15-Day Injured List With Oblique Strain
Juan Soto

Still on Track to Return Next Week
Los Angeles Angels

Garret Anderson Dies at 53 Years Old
Mike Malott

A Favorite At UFC Winnipeg
Gilbert Burns

Set For UFC Winnipeg Main Event
Kyler Phillips

Set UFC Winnipeg Co-Main Event
Charles Jourdain

Looks To Extend His Win Streak
Jai Herbert

An Underdog At UFC Winnipeg
Mandel Nallo

Set For His UFC Debut
Karine Silva

Looks To Get Back In The Win Column
Jasmine Jasudavicius

Looks To Bounce Back
Robert Thomas

Wraps Up Season With a Hat Trick
Macklin Celebrini

Establishes Sharks' New Scoring Record
Scott Wedgewood

Keeps Kraken From Scoring Thursday
Nathan MacKinnon

Wins Rocket Richard Trophy With 53 Goals
Connor McDavid

Secures Sixth Art Ross Trophy With Four-Assist Performance
Connor Dewar

Ready for Game 1
Nikita Grebenkin

Unavailable at Start of Playoffs
Parker Messick

Flirts With No-Hitter in Latest Gem Against Orioles
Mike Trout

Hits Five Homers in Series Versus Yankees
CGY

Arsenii Sergeev to Make NHL Debut Thursday
Aleksander Barkov

Cleared for World Championship
Pierre-Luc Dubois

Dealing With Fractured Hand
Zach Whitecloud

Ready to Rock Thursday
Spencer Arrighetti

Fans 10 in Season Debut, to Remain a Focal Point in Rotation?
Nick Pivetta

Dealing With Flexor Strain, Could Miss Months
Nico Hoerner

Homers, Drive in Five in Win Over Phillies
Shota Imanaga

Strikes Out 11 in First Win of the Season
Sal Stewart

Continues to Hit, Goes Deep Twice on Wednesday
Shohei Ohtani

Strikes Out 10 in Win Over Mets
Shohei Ohtani

Will Pitch on Wednesday, But Won't DH
CFB

Michigan Lands Commitment From Quarterback Kamden Lopati
Sahith Theegala

Brings Strong Form Into Harbour Town
Wyndham Clark

Needs Putter to Show Up at RBC Heritage
Jacob Bridgeman

Looks to Return to Elite Form at Harbour Town
J.J. Spaun

a Volatile Option at RBC Heritage
PGA

Sungjae Im Offers High-Upside Value at RBC Heritage
Matt Fitzpatrick

Set for Another Strong Showing at RBC Heritage
Jason Day

Eyes Bounce-Back After Sunday Struggles at the Masters
Akshay Bhatia

Looking to Rebound at Harbour Town
Cameron Young

Hoping to Secure Second Win of Season at RBC Heritage
Scottie Scheffler

Looks to Win Again at RBC Heritage
Shane Lowry

Has Disappointing Final Round at Masters
Viktor Hovland

Hoping to Build on Final Round at Masters
Brian Harman

Struggling For Consistency Heading to RBC Heritage
Chris Gotterup

Putting Together Outstanding 2026 Season
Justin Thomas

Looks to Defend in Hilton Head
Jordan Spieth

in Search of Improved Putting at RBC Heritage
Marco Penge

May Continue Up-and-Down Ride at the RBC Heritage
Xander Schauffele

Could Get The Job Done at RBC Heritage
Jake Knapp

Keeps Building Strong Results in 2026
Kurt Kitayama

Trying to Regain Form From Florida
Collin Morikawa

Continues to be a Scary DFS Play at RBC Heritage
CFB

Tramell Jones Jr. Outperforms Aaron Philo During Florida's Spring Scrimmage
CFB

Keelon Russell Flashes in Alabama's Spring Game
Ty Gibbs

Holds off the Field for His First Cup Series Victory at Bristol
Ryan Blaney

Earns His First Runner-Up Finish at Bristol
Kyle Larson

Dominant Performance At Bristol Falls Short of Victory
Tyler Reddick

Matches his Career-Best Finish at Bristol
Alex Bowman

Crashes Early at Bristol in Return From Injury
Carlos Ulberg

Is The New Light Heavyweight Champion
Jiří Procházka

Jiri Prochazka Suffers First-Round Knockout Loss
Azamat Murzakanov

Suffers His First Loss
Paulo Costa

Wins Back-to-Back Fights
Curtis Blaydes

Drops Decision At UFC 327
Josh Hokit

Remains Unbeaten
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF