X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Daily Fantasy Football Lineup Picks (Week 16): NFL DFS Advice

RotoBallers, welcome to Week 16 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 16 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 16!

 

DraftKings Quarterbacks - Week 16 DFS Picks

Matthew Stafford - DET @ CIN (DK - $6,200)

Stafford is looking like one of the better options at quarterback this week for a number of reasons. First off, the Lions still have something to play for, so he will be doing all he can to get the win. We know he has multi touchdown upside, as he has done nine times this season. Stafford has put up 17 or more DraftKings points in seven of his last nine games, and has shown to be super consistent. He makes a great play in any format this week, as he is up against the Bengals who have the 18th DVOA against the pass.

Cam Newton - CAR vs TB (DK - $6,800)

Newton has scored 15 or more DraftKings points in six straight games, and is up against one of the worst defenses in the league. He is playing the Buccaneers, who have the 29th DVOA against the pass, and the 21st DVOA against the run. This is a prime spot for him, and he has shown his rushing upside in recent weeks. He has 50 or more rushing yards in five of his last six games, bringing plenty of tournament upside with him.

 

DraftKings Running Backs - Week 16 DFS Picks

Kenyan Drake - MIA @ KC (DK - $7,100)

Drake is up against the Chiefs, who have the 31st DVOA against the run, putting him in a great spot this week. Over the past four week, Drake has 80% of the Dolphins rushing attempts, which means he is their lead back and will be in the game regardless of the situation. The game script isn't saying they will be in this game, as they are a 10 point underdog, but if they want a shot in this game, they will run the ball a lot and slow the game down, putting Drake in a spot to succeed.

Christian McCaffrey - CAR vs TB (DK - $6,400)

McCaffrey brings a dual threat out of the backfield, as he has seen 22 targets over his last four games. He isn't a pure running back and has only gone for a season high of 66 yards this season, but saw double digit rushing attempts last week for the first time since Week 9. This is an encouraging sign, which should benefit him this week, since his opponent has a very bad defense. He is up against the Buccaneers, who have the 21st DOVA against the pass, and the 23rd DVOA against running backs in the passing game. Prime match up for him, and the Panthers are still in a spot where they need to win games, so they won't easy off the gas.

 

DraftKings Wide Receivers - Week 16 DFS Picks

Robert Woods - LAR @ TEN (DK - $6,500)

Woods is back from his injury, and last week he put six receptions 45 yards, and one touchdown. He is good mid range option who has some PPR upside against a Titans team who has the 24th DVOA against the pass. This puts him in a good spot, since the Rams still have something to play for, and will not be resting their starters. Woods has multi touchdown upside, which he has shown in the games before his injury.

Chris Godwin - TB @ CAR (DK - $3,000)

With DeSean Jackson being out of practice yet again on Thursday, Godwin is in a spot to see increased targets, as he did last week, after Jackson left the game early with the injury. Last week he ended with five receptions for 68 yards, for a total of 11.8 DraftKings points. He is also super cheap on DraftKings, so the savings he brings to your lineup will allow you to get up to the higher priced players.

 

DraftKings Tight End - Week 16 DFS Pick

Eric Ebron - DET @ CIN (DK - $3,700)

Everyone and their mother is talking about Antonio Gates this week as a tight end option, since he is so cheap, and will be seeing more targets now that Hunter Henry is done for the year. If you want another option at tight end, look at Ebron. he is up against the Bengals who have the 30th DVOA vs tight ends, and have suffered major losses on their defense. He has 15 receptions over his last two games, and with the Lions needing to win games to stay in the playoff picture, he will see plenty of snaps.

 

DraftKings Defense - Week 16 DFS Pick

Detroit Lions @ Cincinnati Bengals

The Lions are in a spot where they need to win games to try and make the playoffs, so look to their defense to step up against a weak Bengals team. Last week against the Vikings we saw that the Bengals have all but given up on the season, making them a nice target this week. The Lions have seven sacks over their last four games, along with five interceptions in that span. They have turnover potential against this weak Bengals offense.

 

More Weekly DFS Analysis





REAL-TIME FANTASY NEWS

Jason Day

Looks to Keep Long-Running Success Going at Pebble Beach
Hunter Strickland

Re-Signs With Angels on Minors Deal
Pierceson Coody

to Keep Good Form Going at First Career Pebble Beach Appearance
Colin Rea

on the Outside Looking in for Rotation Spot
Emilio Pagán

Emilio Pagan Will be Slow-Played in Spring Training
Chase Dollander

Makes Tweaks Entering Second Season
Sam Burns

Needs a Good Showing at Pebble Beach to Shift Fleeting Momentum
Junior Caminero

Reportedly Trims Down, Appears in Great Shape
Daylen Lile

Nestling Into Large Role for 2026
Sandy Alcantara

Fantasy Managers Looking for Sandy Alcantara to Return to Ace Form
Colson Montgomery

Shows That His Power is Here to Stay
Salvador Perez

Continue to Show Off His Power
Sal Frelick

Continues to Offer an Impact Bat and Glove
Giancarlo Stanton

Elbow Will be Monitored in 2026
Jett Williams

to See Third Base Reps at Spring Training
Gio Urshela

Agrees to Minor-League Deal With Twins
Ben Casparius

Building Up as Starting Pitcher
Jarren Duran

Could Hit the Bench Against Lefties
Carson Benge

Mets Invite Carson Benge to Spring Training
Anthony Seigler

Heads to Boston in Trade
Ivica Zubac

Uncertain for Pacers Debut Tuesday
Andruw Monasterio

Red Sox Acquire Andruw Monasterio From Brewers
Mitchell Robinson

Won't Play on Tuesday
Jayson Tatum

Takes Part in G-League Practice
OG Anunoby

is Tagged as Questionable for Tuesday
Shane McClanahan

Expected to be Ready by Opening Day
Dyson Daniels

Sidelined Monday, CJ McCollum Enters Starting Five
Shane Drohan

Brewers Acquire Pitcher Shane Drohan From Red Sox
David Hamilton

Brewers Acquire Infielder David Hamilton From Boston
Jalen Johnson

Ruled Out Monday vs. Timberwolves
Wendell Carter Jr.

is Cleared for Monday's Game
Guerschon Yabusele

Jalen Smith Out Monday, Guerschon Yabusele to Start
Tre Jones

Josh Giddey, Tre Jones Miss Monday vs. Nets
Bennedict Mathurin

Set for Clippers Debut on Tuesday
Kenneth Walker III

Runs Away With Super Bowl MVP Honors
Johnny Furphy

Out for Remainder of Season
Franz Wagner

Good to Go Versus Bucks
Deandre Ayton

Active Against Thunder
Doug McDermott

Set to Suit Up Monday
Domantas Sabonis

Unavailable on Monday
Vinicius Oliveira

Suffers His First UFC Loss
Mario Bautista

Gets Back In The Win Column
Kyoji Horiguchi

Dominates At UFC Vegas 113
Amir Albazi

Gets Dominated At UFC Vegas 113
Rizvan Kuniev

Earns His First UFC Win
Jailton Almeida

Drops Decision At UFC Vegas 113
Marc-Andre Barriault

Loses Back-To-Back Fights
Michal Oleksiejczuk

Gets His Third Win In A Row
Las Vegas Raiders

Klint Kubiak Confirms he Will be Next Raiders Head Coach
Jonas Rondbjerg

Out for Olympics
Brad Marchand

Good to Go for Olympic Opener
Gabriel Landeskog

Healthy for Olympics
Jack Hughes

Cleared for Olympics
Robert Williams III

Listed as Questionable vs. Philadelphia
Jaylon Tyson

Could Miss First Game Since November
Scoot Henderson

Probable Monday vs. 76ers
Cedric Coward

Set to Return Monday Against Warriors
Santi Aldama

Out Again Monday Against Warriors
Ajay Mitchell

Ruled Out Against Lakers
Jaxon Smith-Njigba

Returns to Super Bowl After Injury Scare
Jaxon Smith-Njigba

Being Evaluated for Concussion, Questionable to Return
James Pearce Jr.

Arrested Following Police Chase
Quinn Hughes

Enters Olympics in Red-Hot Form
NHL

Juho Lammikko Returns to Switzerland
Pavel Zacha

Misses Olympics
Travis Kelce

Undecided on Playing Future, Leaning Towards Returning in 2026?
CFB

Rutgers Hiring South Dakota Head Coach Travis Johansen as Defensive Coordinator
Vinicius Oliveira

Looks For His Seventh Consecutive Win
Mario Bautista

A Favorite At UFC Vegas 113
Kyoji Horiguchi

Set For UFC Vegas 113 Co-Main Event
Amir Albazi

Looks To Bounce Back
Rizvan Kuniev

Looks For His First UFC Win
Jailton Almeida

Looks To Get Back In The Win Column
Marc-Andre Barriault

In Dire Need Of Victory
Michal Oleksiejczuk

Looks For His Third Win In A Row
Michael Penix Jr.

Says he's Ahead of Schedule After Knee Surgery
Cleveland Browns

Jim Schwartz Resigns as Browns Defensive Coordinator
Malik Nabers

Says his Rehab has Been "Phenomenal"
CFB

Oklahoma Hiring Former NFL Defensive Lineman DeShawn Williams to Analyst Role
CFB

Jahmal Edrine Charged with Sexual Assault, No Longer Enrolled at Virginia
Jakob Chychrun

Makes Big Impact in Thursday's Win
Brandon Bussi

Shuts Out Rangers With 16 Saves
Anze Kopitar

Reaches 1,300 Career Points
Mark Stone

Becomes First Vegas Player With 100 Multi-Point Games
Daniil Tarasov

Injured in Battle of Florida
Andrei Kuzmenko

Hurt Versus Vegas
John Carlson

Suffers Lower-Body Injury
Matthew Stafford

Named 2025 NFL MVP, Will Return in 2026
Jaxon Smith-Njigba

Takes Home Offensive Player of the Year Honors
Christian McCaffrey

Named Comeback Player of the Year
Tetairoa McMillan

Named Offensive Rookie of the Year
Myles Garrett

Unanimously Wins Defensive Player of the Year Award
Brad Marchand

Evan Rodrigues Among Panthers Absentees Thursday
Calum Ritchie

Rejoins Islanders Lineup as Second-Line Center
Zach Benson

Sits Out Second Straight Game
Pierre-Luc Dubois

Available Against Predators
Rickard Rakell

Out Thursday
Brayden Point

Won't Play in Olympics
Jonathan Huberdeau

to Have Season-Ending Hip Surgery
CFB

Houston, Vanderbilt, Tennessee Land Top-Three QBs in 2026 Class
Joe Mixon

Committed to Playing in 2026
CFB

Michigan Signs Top-15 Recruiting Class Despite Coaching Change
CFB

USC Finishes with No. 1 Signing Class in 2026
CFB

Trinidad Chambliss Denied Medical Redshirt Waiver By NCAA
CFB

Sam Leavitt to be Limited In Spring Practice
Jordan Love

Avoids Offseason Surgery
Matt Fitzpatrick

Back in Action at WM Phoenix Open
Sahith Theegala

Riding Hot Start Into WM Phoenix Open
J.J. Spaun

Looks to Regain Form at WM Phoenix Open
Viktor Hovland

a Volatile Option at WM Phoenix Open
Rasmus Hojgaard

Aims to Build on Solid Start to 2026
Brian Harman

Looks to Find Form at WM Phoenix Open
Daniel Berger

Has the Tools to Go One Step Higher at Scottsdale
Max Greyserman

Searching for Consistency at WM Phoenix Open
Jake Knapp

Wants Revenge at WM Phoenix Open
CFB

Joey Aguilar Granted Temporary Restraining Order Against NCAA
Joel Dahmen

Carrying Momentum Into WM Phoenix Open
Corey Conners

Unlikely to Contend at Scottsdale
Sepp Straka

Seeks a Rebound After The American Express
Jordan Spieth

Healthy Heading to WM Phoenix Open
Keith Mitchell

Building Momentum for Event in Scottsdale
Tom Hoge

The Tom Hoge Roller Coaster Heads to Scottsdale for WM Phoenix Open
Rickie Fowler

Worth a Look at WM Phoenix Open
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF