X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Daily Fantasy Football Lineup Picks (Week 16): NFL DFS Advice

RotoBallers, welcome to Week 16 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 16 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 16!

 

DraftKings Quarterbacks - Week 16 DFS Picks

Matthew Stafford - DET @ CIN (DK - $6,200)

Stafford is looking like one of the better options at quarterback this week for a number of reasons. First off, the Lions still have something to play for, so he will be doing all he can to get the win. We know he has multi touchdown upside, as he has done nine times this season. Stafford has put up 17 or more DraftKings points in seven of his last nine games, and has shown to be super consistent. He makes a great play in any format this week, as he is up against the Bengals who have the 18th DVOA against the pass.

Cam Newton - CAR vs TB (DK - $6,800)

Newton has scored 15 or more DraftKings points in six straight games, and is up against one of the worst defenses in the league. He is playing the Buccaneers, who have the 29th DVOA against the pass, and the 21st DVOA against the run. This is a prime spot for him, and he has shown his rushing upside in recent weeks. He has 50 or more rushing yards in five of his last six games, bringing plenty of tournament upside with him.

 

DraftKings Running Backs - Week 16 DFS Picks

Kenyan Drake - MIA @ KC (DK - $7,100)

Drake is up against the Chiefs, who have the 31st DVOA against the run, putting him in a great spot this week. Over the past four week, Drake has 80% of the Dolphins rushing attempts, which means he is their lead back and will be in the game regardless of the situation. The game script isn't saying they will be in this game, as they are a 10 point underdog, but if they want a shot in this game, they will run the ball a lot and slow the game down, putting Drake in a spot to succeed.

Christian McCaffrey - CAR vs TB (DK - $6,400)

McCaffrey brings a dual threat out of the backfield, as he has seen 22 targets over his last four games. He isn't a pure running back and has only gone for a season high of 66 yards this season, but saw double digit rushing attempts last week for the first time since Week 9. This is an encouraging sign, which should benefit him this week, since his opponent has a very bad defense. He is up against the Buccaneers, who have the 21st DOVA against the pass, and the 23rd DVOA against running backs in the passing game. Prime match up for him, and the Panthers are still in a spot where they need to win games, so they won't easy off the gas.

 

DraftKings Wide Receivers - Week 16 DFS Picks

Robert Woods - LAR @ TEN (DK - $6,500)

Woods is back from his injury, and last week he put six receptions 45 yards, and one touchdown. He is good mid range option who has some PPR upside against a Titans team who has the 24th DVOA against the pass. This puts him in a good spot, since the Rams still have something to play for, and will not be resting their starters. Woods has multi touchdown upside, which he has shown in the games before his injury.

Chris Godwin - TB @ CAR (DK - $3,000)

With DeSean Jackson being out of practice yet again on Thursday, Godwin is in a spot to see increased targets, as he did last week, after Jackson left the game early with the injury. Last week he ended with five receptions for 68 yards, for a total of 11.8 DraftKings points. He is also super cheap on DraftKings, so the savings he brings to your lineup will allow you to get up to the higher priced players.

 

DraftKings Tight End - Week 16 DFS Pick

Eric Ebron - DET @ CIN (DK - $3,700)

Everyone and their mother is talking about Antonio Gates this week as a tight end option, since he is so cheap, and will be seeing more targets now that Hunter Henry is done for the year. If you want another option at tight end, look at Ebron. he is up against the Bengals who have the 30th DVOA vs tight ends, and have suffered major losses on their defense. He has 15 receptions over his last two games, and with the Lions needing to win games to stay in the playoff picture, he will see plenty of snaps.

 

DraftKings Defense - Week 16 DFS Pick

Detroit Lions @ Cincinnati Bengals

The Lions are in a spot where they need to win games to try and make the playoffs, so look to their defense to step up against a weak Bengals team. Last week against the Vikings we saw that the Bengals have all but given up on the season, making them a nice target this week. The Lions have seven sacks over their last four games, along with five interceptions in that span. They have turnover potential against this weak Bengals offense.

 

More Weekly DFS Analysis





REAL-TIME FANTASY NEWS

Dylan Crews

Optioned to Triple-A Rochester
Quinshon Judkins

Does Quinshon Judkins Have RB1 Upside in Dynasty Formats?
Jayden Reed

Is Jayden Reed a Buy-Low Candidate After Injury-Marred 2025 Campaign?
Lerone Murphy

Set For UFC London Main Event
Chris Olave

Rehabs his Dynasty Value With Resurgent 2025 Performance
Movsar Evloev

Looks To Remain Unbeaten
Tyrone Tracy Jr.

Facing Uphill Battle for Playing Time in New York
Michael Aswell

Jr. An Underdog At UFC London
Luke Riley

Set For UFC London Co-Main Event
Chimere Dike

Could See a Diminished Role in 2026
Joe Ryan

Named Opening Day Starter for Twins
Chase Brown

Profiles as a High-End Dynasty Running Back Heading into 2026
Sam Patterson

Looks To Extend His Win Streak
Michael Page

Set For Welterweight Bout
Austen Lane

In Dire Need Of Victory
Iwo Baraniewski

A Favorite At UFC London
C.J. Stroud

Will C.J. Stroud Ever Rediscover his Rookie-Season Magic?
Bijan Robinson

Finally Has the Falcons' Backfield All to Himself
Najee Harris

Remains on the Open Market
George Kittle

Injury Complicates Price Tag
Jameson Williams

Flashes WR1 Upside Ahead of 2026
Parker Washington

a Solidified Fantasy Option Despite Crowded Offense?
Nico Collins

Has Yet to Reach His Full Potential
Collin Murray-Boyles

Unlikely to Play Friday
Jonathan Kuminga

Ruled Out Friday Against Rockets
Aaron Gordon

Off Injury Report Against Toronto
Sergei Bobrovsky

Shuts Out Oilers with 21 Saves
Peyton Watson

Not Yet Ready to Return Friday
Gary Trent Jr.

Exits Thursday with Adductor Issue
Trent Frederic

Exits Early Against Panthers
Malik Monk

Leaves Early Thursday With Shoulder Injury
Mason Appleton

Hurt Thursday Night
Lauri Markkanen

Out at Least Two More Weeks
Tyler Toffoli

Suffers Lower-Body Injury in Thursday's Loss
Victor Hedman

Makes Early Exit Due to Illness
Juuse Saros

Dealing with Upper-Body Injury
Rome Odunze

Steps Into a Larger Role for 2026
Baker Mayfield

Loses Top Receiver After Subpar Season
Ray Davis

' Fantasy Managers Continue to Exercise Patience
Ja'Marr Chase

Has Overall WR1 Upside with Quarterback Healthy
Javonte Williams

Still Penciled Into Workhorse Role
Quentin Johnston

Expected to Handle More Targets in 2026?
Los Angeles Chargers

Derwin James Suffers Minor Injury
Spencer Knight

Shuts Down the Wild on Thursday
Adam Fantilli

Scores Two Goals in Victory
Francisco Alvarez

Pulled Early Thursday With Back Tightness
Amir Coffey

Exits Early with Ankle Sprain
Daeqwon Plowden

Moves Into Starting Lineup Thursday
Jaxon Smith-Njigba

the WR1 Overall in Fantasy After Career Year?
Noah Clowney

Won't Play Friday Vs. New York
GG Jackson II

Unlikely to Play Against Boston
Naz Reid

Could Sit Again Friday
Josh Hart

Ruled Out Friday Against Brooklyn
Jalen Brunson

Set to Play Against Brooklyn
Brice Sensabaugh

Out Against Milwaukee
John Konchar

Out Thursday Against Bucks
Kyle Kuzma

Ready to Play Thursday Vs. Utah
Myles Turner

Set to Return Versus Jazz
Kevin Porter Jr.

Sidelined Against Utah
Donovan Mitchell

Ruled Out, Jaylon Tyson to Start Thursday
Auston Matthews

Ruled Out for 12 Weeks
Austin Reaves

Cleared to Play Thursday
Yaroslav Askarov

Still Out Thursday
Luis Severino

to Start for A's on Opening Day
Kirill Kaprizov

Won't Play Against Blackhawks
Alex Tuch

Expected to Return Thursday
Noah Laba

Unavailable Against Blue Jackets
Andrew Copp

Returns From Three-Game Absence
Josh Anderson

Won't Play Thursday
Logan Gilbert

Named Mariners Opening Day Starter
José Ramírez

Jose Ramirez Back in Cactus League Lineup on Thursday
Hayden Birdsong

to Have Tommy John Surgery, Miss Entire 2026 Season
Zack Wheeler

to Pitch in Minor-League Game on Monday
Paul Skenes

Pirates Officially Name Paul Skenes Their Opening Day Starter
Jurickson Profar

Officially Suspended for Entire 2026 Season
Carson Williams

"Likely" to Be Rays Opening Day Starting Shortstop
Trey Yesavage

Will Open 2026 on the Injured List Due to Shoulder Impingement
Jack Hughes

Posts Another Three-Point Performance in Victory
Jackson Blake

Collects Three Points on Wednesday
WAS

Cole Hutson Scores in NHL Debut on Wednesday
Max Fried

to Start on Opening Day for Yankees
Arizona Diamondbacks

Diamondbacks Not Naming a Closer to Begin the Season
Adrian Kempe

Could Return Thursday
Mason McTavish

Sits Out Second Consecutive Game
Ross Johnston

to Miss 3-4 Weeks
Matthew Liberatore

Named Cardinals Opening Day Starter
Roki Sasaki

to be in Opening Day Starting Rotation
Akshay Bhatia

Withdraws From Valspar Championship
José Berríos

Jose Berrios has Stress Fracture, Won't be Ready for Opening Day
CFB

Alberto Mendoza Drawing Positive Reviews at Georgia Tech
CFB

Anthony Colandrea Impressing in Nebraska's Spring Practices
J.J. Spaun

Offers Upside Despite Poor Course History at Innisbrook
Jeremy Peña

Opening Day "Not Ruled Out" for Jeremy Pena
Aaron Rai

Looks to Bounce Back at Valspar Championship
Johnny Keefer

Brings Ball-Striking Upside to Valspar Championship
Billy Horschel

a Volatile Play at Valspar Championship
Ben Griffin

Looks to Rebound at the Valspar Championship
Corey Conners

Brings Elite Ball-Striking to Valspar Championship
Cole Ragans

Named Royals Opening Day Starter
Xander Schauffele

Trending In The Right Direction For Valspar Championship
Sahith Theegala

Has Shot to Challenge at Valspar Championship
Mackenzie Hughes

Looking to Bounce Back at Valspar Championship
Nicolai Hojgaard

Finding Rhythm For Valspar Championship
Matt Fitzpatrick

Continues Hot Start to 2026 Heading to Valspar Championship
Pierceson Coody

Heads to Valspar Championship Following Two Missed Cuts
Shohei Ohtani

to Pitch in Cactus League Game on Wednesday
Seiya Suzuki

has Sprained Knee, Opening Day Availability Unclear
Wyndham Clark

Searching for Momentum at Valspar Championship
Justin Thomas

Is Justin Thomas Back Ahead of This Week's Valspar Championship?
Jordan Spieth

to Bounce Back at Favored Valspar Championship?
Brooks Koepka

is Starting to Find His Groove Again Ahead of Valspar Championship
Viktor Hovland

is One of The Best DFS Plays at Innesbrook
Rasmus Hojgaard

to Get Back on Track at Valspar Championship
Tony Finau

is Again a Scary Option at Valspar Championship
Blades Brown

Continues PGA Tour Run at Valspar Championship
Josh Emmett

Suffers First-Round TKO Loss
Kevin Vallejos

Scores First-Round TKO
Amanda Lemos

Drops Back-To-Back Fights
Gillian Robertson

Extends Her Win Streak
Andre Fili

Drops Decision on Saturday
Denny Hamlin

Dominates and Gets His Third Career Las Vegas Win
Chase Elliott

Earns Runner-Up Finish at Las Vegas
William Byron

Wins A Stage and Finishes Third at Las Vegas
Christopher Bell

Finishes Fourth at Las Vegas After Strong Run
Kyle Larson

Fades to Seventh Despite Leading Laps Early at Las Vegas
Andre Fili

Jose Delgado Edges Andre Fili in Split-Decision Win
Oumar Sy

Suffers First-Round Submission Loss
Ion Cutelaba

Returns To The Win Column
CFB

CJ Carr Enters Sophomore Season as Heisman Favorite
CFB

Aaron Philo Not a Lock to be Florida's Starting QB?
CFB

George MacIntyre the Favorite to Win Tennessee Quarterback Battle?
CFB

Keelon Russell, Austin Mack Battling for Alabama QB1 Duties
Christopher Bell

Looking for Redemption, Wins Pole at Las Vegas
Denny Hamlin

Should Contend for Another Vegas Win
Chase Briscoe

Qualifies 18th Despite Toyota Dominating at Las Vegas
Chase Elliott

May Fly Under the Radar at Las Vegas
NASCAR

Ross Chastian Has Been As Solid As They Come at Las Vegas
Ty Gibbs

Could Ty Gibbs Finally Break Through With a Win at Las Vegas?
Brad Keselowski

a Solid DFS Pick at Las Vegas
Kyle Larson

Should Kyle Larson be Considered A Favorite for Las Vegas?
William Byron

Could Compete for a Top-Five Finish at Las Vegas
Ryan Blaney

Is Ryan Blaney Worth Rostering in Tournament DFS Lineups for Las Vegas?
Tyler Reddick

Could Continue his Top-10 Streak at Las Vegas
Joey Logano

Should DFS Managers Underestimate Joey Logano for Las Vegas?
Chris Buescher

Is Chris Buescher Worth Rostering For Las Vegas DFS Lineups?
NASCAR

Bubba Wallace is A Risky DFS Option Who Could Pay Off at Las Vegas
Josh Berry

Has Plenty of Upside for Las Vegas DFS Lineups
Ryan Preece

Scores his First Las Vegas Top-10 Starting Spot in Qualifying
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF