🖥 TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Daily Fantasy Football Lineup Picks (Week 16): NFL DFS Advice

RotoBallers, welcome to Week 16 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 16 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 16!

 

DraftKings Quarterbacks - Week 16 DFS Picks

Matthew Stafford - DET @ CIN (DK - $6,200)

Stafford is looking like one of the better options at quarterback this week for a number of reasons. First off, the Lions still have something to play for, so he will be doing all he can to get the win. We know he has multi touchdown upside, as he has done nine times this season. Stafford has put up 17 or more DraftKings points in seven of his last nine games, and has shown to be super consistent. He makes a great play in any format this week, as he is up against the Bengals who have the 18th DVOA against the pass.

Cam Newton - CAR vs TB (DK - $6,800)

Newton has scored 15 or more DraftKings points in six straight games, and is up against one of the worst defenses in the league. He is playing the Buccaneers, who have the 29th DVOA against the pass, and the 21st DVOA against the run. This is a prime spot for him, and he has shown his rushing upside in recent weeks. He has 50 or more rushing yards in five of his last six games, bringing plenty of tournament upside with him.

 

DraftKings Running Backs - Week 16 DFS Picks

Kenyan Drake - MIA @ KC (DK - $7,100)

Drake is up against the Chiefs, who have the 31st DVOA against the run, putting him in a great spot this week. Over the past four week, Drake has 80% of the Dolphins rushing attempts, which means he is their lead back and will be in the game regardless of the situation. The game script isn't saying they will be in this game, as they are a 10 point underdog, but if they want a shot in this game, they will run the ball a lot and slow the game down, putting Drake in a spot to succeed.

Christian McCaffrey - CAR vs TB (DK - $6,400)

McCaffrey brings a dual threat out of the backfield, as he has seen 22 targets over his last four games. He isn't a pure running back and has only gone for a season high of 66 yards this season, but saw double digit rushing attempts last week for the first time since Week 9. This is an encouraging sign, which should benefit him this week, since his opponent has a very bad defense. He is up against the Buccaneers, who have the 21st DOVA against the pass, and the 23rd DVOA against running backs in the passing game. Prime match up for him, and the Panthers are still in a spot where they need to win games, so they won't easy off the gas.

 

DraftKings Wide Receivers - Week 16 DFS Picks

Robert Woods - LAR @ TEN (DK - $6,500)

Woods is back from his injury, and last week he put six receptions 45 yards, and one touchdown. He is good mid range option who has some PPR upside against a Titans team who has the 24th DVOA against the pass. This puts him in a good spot, since the Rams still have something to play for, and will not be resting their starters. Woods has multi touchdown upside, which he has shown in the games before his injury.

Chris Godwin - TB @ CAR (DK - $3,000)

With DeSean Jackson being out of practice yet again on Thursday, Godwin is in a spot to see increased targets, as he did last week, after Jackson left the game early with the injury. Last week he ended with five receptions for 68 yards, for a total of 11.8 DraftKings points. He is also super cheap on DraftKings, so the savings he brings to your lineup will allow you to get up to the higher priced players.

 

DraftKings Tight End - Week 16 DFS Pick

Eric Ebron - DET @ CIN (DK - $3,700)

Everyone and their mother is talking about Antonio Gates this week as a tight end option, since he is so cheap, and will be seeing more targets now that Hunter Henry is done for the year. If you want another option at tight end, look at Ebron. he is up against the Bengals who have the 30th DVOA vs tight ends, and have suffered major losses on their defense. He has 15 receptions over his last two games, and with the Lions needing to win games to stay in the playoff picture, he will see plenty of snaps.

 

DraftKings Defense - Week 16 DFS Pick

Detroit Lions @ Cincinnati Bengals

The Lions are in a spot where they need to win games to try and make the playoffs, so look to their defense to step up against a weak Bengals team. Last week against the Vikings we saw that the Bengals have all but given up on the season, making them a nice target this week. The Lions have seven sacks over their last four games, along with five interceptions in that span. They have turnover potential against this weak Bengals offense.

 

More Weekly DFS Analysis





POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Davante Adams

Not Expected to Play in Week 18
Stephon Castle

Active on Wednesday
Tyler Kolek

Elevated to Available on Wednesday
Tari Eason

Questionable Versus Brooklyn
Tobias Harris

Not Expected to Suit Up on Thursday
Ariel Hukporti

Available For Wednesday
Alperen Sengün

Alperen Sengun Questionable Versus Brooklyn
Mason Plumlee

Undergoes Groin Surgery
Zach Collins

Out at Least 10 More Days
Jerami Grant

Unavailable Again on Wednesday
Geno Smith

Won't Play in Week 18
Aaron Rodgers

Considering Playing Beyond 2025?
Sean Monahan

Sits Out Wednesday's Game
Zach Werenski

Misses Fourth Straight Game Wednesday
Dougie Hamilton

Questionable Wednesday
Radko Gudas

Expected to Remain Out Wednesday
Stefon Diggs

Expected to Play in Week 18
Ilya Lyubushkin

Back From One-Game Absence Wednesday
Alex Lyon

to Miss "Bit of Time"
Erik Cernak

Rejoins Lightning Lineup Wednesday
Christian McCaffrey

Trending to Play in Week 18
Kon Knueppel

To Make Return For Charlotte On Wednesday, In Starting Lineup
Jalen Hurts

Eagles Expected to Rest Jalen Hurts, Most Starters in Week 18
George Kittle

49ers Will be "Very Surprised" if George Kittle Doesn't Play on Saturday
Marvin Harrison Jr.

Ruled Out for Regular-Season Finale
CFB

Lane Kiffin Interested in Sam Leavitt, Brendan Sorsby at LSU
Shakir Mukhamadullin

Questionable Wednesday
Adam Gaudette

Unavailable Wednesday
Darcy Kuemper

Activated From Injured Reserve
Alex Lyon

Nursing Lower-Body Injury
William Karlsson

to Miss Olympics
Jack Eichel

a Game-Time Decision Wednesday
Jason Dickinson

Hurt Versus Islanders
Mitchell Robinson

Sits Out Wednesday's Game
Grayson Allen

Listed as Doubtful Wednesday
Mason Plumlee

Ryan Kalkbrenner, Mason Plumlee Remain Out Wednesday
Kon Knueppel

Likely to Return Wednesday
Miles Bridges

Listed as Questionable Wednesday
Isaiah Hartenstein

Misses Second Straight Game
Devin Vassell

Ruled Out for Wednesday
Stephon Castle

Iffy for Wednesday
Josh Giddey

Sidelined "at Least a Few Weeks"
Desmond Bane

Might Miss Wednesday's Game in Indiana
Jalen Suggs

on the Injury Report Again for Wednesday Night
Connor Dewar

Available Tuesday
TOR

Chris Tanev to Miss Time With Lower-Body Injury
Dakota Joshua

Out With Kidney Problem
MON

Samuel Montembeault Returns to Canadiens Crease
Erik Karlsson

Good to Go Tuesday
William Nylander

Misses Second Consecutive Game
Auston Matthews

a Game-Time Call Tuesday
CFB

Deuce Knight Officially Entering Transfer Portal
CFB

Kewan Lacy Expected to Be Full-Go Against Georgia
Stefon Diggs

Facing Strangulation, Assault Charges
CFB

Chip Kelly Named Northwestern Offensive Coordinator
Riley Leonard

Will Start Against the Texans
Bijan Robinson

Explodes for 229 Total Yards, Two Touchdowns on Monday Night
Davante Adams

Officially Out on Monday Night
Drake London

Active Against Rams
Justin Herbert

Won't Face Broncos in Week 18
Marcus Mariota

Considered "a Stretch" to Play in Week 18
Geno Smith

Dealing With Significant Ankle Injury
Dak Prescott

Will Play in Week 18
Lamar Jackson

Week 18 Status "to be Determined"
Joe Mixon

Won't Return This Season
T.J. Watt

a Long Shot to Play in Week 18?
CFB

Penn State Working to Hire D'Anton Lynn as Next Defensive Coordinator
Joe Burrow

Will Play in Week 18 Against the Browns
CFB

Omar Cooper Expected to be Full-Go for Rose Bowl
CFB

Marcus Freeman Staying with Notre Dame for 2026 Season
CFB

Star Wideout Cam Coleman Entering Transfer Portal
CFB

Jay Hill Expected to be Next Michigan Defensive Coordinator
CFB

Michigan Targeting Kyle Whittingham as Next Head Coach
CFB

Texas Leading Rusher Quintrevion Wisner Set to Transfer

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP