X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Daily Fantasy Football Lineup Picks (Week 16): NFL DFS Advice

RotoBallers, welcome to Week 16 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 16 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 16!

 

DraftKings Quarterbacks - Week 16 DFS Picks

Matthew Stafford - DET @ CIN (DK - $6,200)

Stafford is looking like one of the better options at quarterback this week for a number of reasons. First off, the Lions still have something to play for, so he will be doing all he can to get the win. We know he has multi touchdown upside, as he has done nine times this season. Stafford has put up 17 or more DraftKings points in seven of his last nine games, and has shown to be super consistent. He makes a great play in any format this week, as he is up against the Bengals who have the 18th DVOA against the pass.

Cam Newton - CAR vs TB (DK - $6,800)

Newton has scored 15 or more DraftKings points in six straight games, and is up against one of the worst defenses in the league. He is playing the Buccaneers, who have the 29th DVOA against the pass, and the 21st DVOA against the run. This is a prime spot for him, and he has shown his rushing upside in recent weeks. He has 50 or more rushing yards in five of his last six games, bringing plenty of tournament upside with him.

 

DraftKings Running Backs - Week 16 DFS Picks

Kenyan Drake - MIA @ KC (DK - $7,100)

Drake is up against the Chiefs, who have the 31st DVOA against the run, putting him in a great spot this week. Over the past four week, Drake has 80% of the Dolphins rushing attempts, which means he is their lead back and will be in the game regardless of the situation. The game script isn't saying they will be in this game, as they are a 10 point underdog, but if they want a shot in this game, they will run the ball a lot and slow the game down, putting Drake in a spot to succeed.

Christian McCaffrey - CAR vs TB (DK - $6,400)

McCaffrey brings a dual threat out of the backfield, as he has seen 22 targets over his last four games. He isn't a pure running back and has only gone for a season high of 66 yards this season, but saw double digit rushing attempts last week for the first time since Week 9. This is an encouraging sign, which should benefit him this week, since his opponent has a very bad defense. He is up against the Buccaneers, who have the 21st DOVA against the pass, and the 23rd DVOA against running backs in the passing game. Prime match up for him, and the Panthers are still in a spot where they need to win games, so they won't easy off the gas.

 

DraftKings Wide Receivers - Week 16 DFS Picks

Robert Woods - LAR @ TEN (DK - $6,500)

Woods is back from his injury, and last week he put six receptions 45 yards, and one touchdown. He is good mid range option who has some PPR upside against a Titans team who has the 24th DVOA against the pass. This puts him in a good spot, since the Rams still have something to play for, and will not be resting their starters. Woods has multi touchdown upside, which he has shown in the games before his injury.

Chris Godwin - TB @ CAR (DK - $3,000)

With DeSean Jackson being out of practice yet again on Thursday, Godwin is in a spot to see increased targets, as he did last week, after Jackson left the game early with the injury. Last week he ended with five receptions for 68 yards, for a total of 11.8 DraftKings points. He is also super cheap on DraftKings, so the savings he brings to your lineup will allow you to get up to the higher priced players.

 

DraftKings Tight End - Week 16 DFS Pick

Eric Ebron - DET @ CIN (DK - $3,700)

Everyone and their mother is talking about Antonio Gates this week as a tight end option, since he is so cheap, and will be seeing more targets now that Hunter Henry is done for the year. If you want another option at tight end, look at Ebron. he is up against the Bengals who have the 30th DVOA vs tight ends, and have suffered major losses on their defense. He has 15 receptions over his last two games, and with the Lions needing to win games to stay in the playoff picture, he will see plenty of snaps.

 

DraftKings Defense - Week 16 DFS Pick

Detroit Lions @ Cincinnati Bengals

The Lions are in a spot where they need to win games to try and make the playoffs, so look to their defense to step up against a weak Bengals team. Last week against the Vikings we saw that the Bengals have all but given up on the season, making them a nice target this week. The Lions have seven sacks over their last four games, along with five interceptions in that span. They have turnover potential against this weak Bengals offense.

 

More Weekly DFS Analysis





REAL-TIME FANTASY NEWS

Keyonte George

is Available to Play on Saturday
De'Anthony Melton

is Returning on Saturday
Draymond Green

is Available on Saturday
Keston Hiura

Exits After Getting Hit by Pitch
Leo De Vries

Exits Early on Saturday
Kyle Stowers

is Dealing with Minor Hamstring Strain
Cody Bellinger

is Dealing with Back Injury
Corbin Carroll

Likely Ready for Opening Day
Vladislav Namestnikov

Out Week-to-Week
Nino Niederreiter

Recovering From Surgery
Colton Parayko

Doubtful for Sunday
Zach Benson

Activated From Injured Reserve
Anthony Cirelli

a Game-Time Decision Saturday
Roope Hintz

Remains Out Saturday
Andrei Kuzmenko

Out Week-to-Week After Meniscus Surgery
Starling Marte

Royals Agree With Starling Marte
Rafael Devers

Being Shut Down for 2-4 Days With Hamstring Tightness
Ronald Acuña Jr.

Ronald Acuna Jr. Hits Grand Slam in Grapefruit League Game
J.J. Wetherholt

JJ Wetherholt Homers for First Spring Hit
Bryce Miller

Shut Down for Five Days With Side Soreness
Spencer Strider

Diminished Velocity a Cause for Concern?
Xander Bogaerts

Can Xander Bogaerts Play a Fully Healthy Season in 2026?
Jordan Beck

Can Jordan Beck Be a 20/20 Outfielder in 2026?
Otto Lopez

Profiles as a Projectable Middle-Infield Option in 2026
Alec Burleson

Carries a Safe Production Floor Heading into 2026
Luis Castillo

May Be Showing Signs of Decline Heading into 2026
Trey Yesavage

to be Ramped Up While in Toronto's Rotation
Alex Lyon

Picks Up Victory Against Former Club
Mikko Rantanen

Likely to Miss More Than Two Weeks
A.J. Brown

Patriots "Have Explored Trade Talks" Involving A.J. Brown
Shane Bieber

Throwing at 120 Feet, Timeline Remains Fuzzy
Josh Lowe

Still Bothered by Oblique
Starling Marte

Royals Discussing Deal With Starling Marte
Ceddanne Rafaela

Roman Anthony, Ceddanne Rafaela Fine After Collision, Playing on Saturday
Deni Avdija

Likely to Miss Another Game
Dallas Mavericks

Tyus Jones Set to be Waived by Dallas
Phoenix Suns

Cole Anthony Parts Ways with Phoenix
Quenton Jackson

Earns Three-Year Deal with Pacers
Mason Plumlee

Staying with Spurs For Remainder Of Season
Devin Booker

Targeting Return Tuesday Or Thursday
Keegan Murray

Out at Least Two Weeks
Tyler Myers

Not Expected to Play Saturday
Luke Hughes

Could Return Saturday
Oskar Sundqvist

Available Saturday
Uvis Balinskis

Exits Early Friday Night
Mark Scheifele

Vladimir Namestnikov Hurt in Friday's Loss
Joel Eriksson Ek

Leaves Game With Facial Injury
Logan Thompson

Defeats the Golden Knights
Norman Powell

Considered Week-to-Week
Pierre-Luc Dubois

Scores Twice in Victory
Jabari Smith Jr.

to Miss Game Vs. Heat
Kristaps Porzingis

Questionable Vs. Lakers
Draymond Green

On Track to Play Saturday
Julian Strawther

Spencer Jones, Julian Strawther Good to Go Vs. Thunder
Jamal Murray

Jalen Pickett Cleared To Play Friday
Dejounte Murray

Won't Play on Saturday
Trey Murphy III

is Ruled Out for Saturday's Game
Caleb Martin

is Unavailable on Friday
Klay Thompson

is Resting on Friday
P.J. Washington

to Remain Out on Friday
Tyler Seguin

Offically Out for Rest of Season
Zach Benson

Could Be an Option Friday
Tom Wilson

Good to Go Friday
John Carlson

to Miss At Least Two More Games
Lone'er Kavanagh

Set For UFC Mexico City Main Event
Brandon Moreno

Looks To Bounce Back
David Martinez

Set For UFC Mexico City Co-Main Event
Marlon Vera

In Dire Need Of Victory
King Green

Looks To Win Back-To-Back Fights
Daniel Zellhuber

Aims To Snap Two-Fight Skid
Felipe Bunes

Looks To Get Back In The Win Column
Édgar Cháirez

Edgar Chairez A Favorite At UFC Mexico City
George Pickens

Cowboys Not Interested in Trading George Pickens
Ashton Jeanty

Not in Line for Workhorse Role in 2026?
Anthony Richardson Sr.

Colts Give Anthony Richardson Sr. Permission to Seek a Trade
Kyler Murray

Prefers to be Released
Derek Carr

"Strong Belief" That Derek Carr is "Very Serious" About Unretiring
Andy Dalton

Is Andy Dalton Available for a Trade?
Keith Mitchell

Making The Comfortable Return to PGA National
CFB

Chandler Morris Suing NCAA for Seventh Year of Eligibility
Chris Kirk

Searching for a Spark at Cognizant Classic
Brooks Koepka

Making Third PGA Tour Start at Cognizant Classic
Mackenzie Hughes

a Steady Option at Cognizant Classic
Seamus Power

Seeking More Green in Florida
PGA

Haotong Li Back From a Break as Florida Stretch Starts
Stephan Jaeger

Trying to Put Four Rounds Together in Florida
PGA

Nico Echavarria Again Attempting to Make the Weekend
Patrick Fishburn

Looking for a Spark at Cognizant Classic
Blades Brown

Set for Cognizant Classic Debut
Michael Thorbjornsen

Looking to Bounce Back at Cognizant Classic
Maxx Crosby

Raiders Expect Maxx Crosby to Return
Billy Horschel

Looks to Improve Season at Cognizant Classic
Kyle Pitts Sr.

Falcons Place Franchise Tag on Kyle Pitts Sr.
Joe Highsmith

Returns to Defend at Cognizant Classic
Quinshon Judkins

Out of Walking Boot, Will be Ready for Training Camp
Breece Hall

Jets Will Use Franchise Tag on Breece Hall if Extension isn't Reached
Joel Dahmen

Needs Better Consistency Heading Into The Florida Swing
Daniel Berger

Looks to Improve Putting as PGA Tour Begins Its Florida Swing
Kirk Cousins

Falcons Plan to Release Kirk Cousins
Zach Ertz

Plans to Return for 14th Season
Davis Thompson

Struggling to Find Birdies as Florida Looms
Tom Kim

Not Quite Cutting It in 2026
Nicolai Hojgaard

Wants to Build Momentum from Scottsdale
Christiaan Bezuidenhout

Returns After Extended Break for Florida Event
CFB

Gunner Rivers Follows His Father, Commits To North Carolina State
Will Zalatoris

Set to Make Tournament Debut at Cognizant Classic
Rasmus Hojgaard

Trending Up at the Cognizant Classic
Anthony Hernandez

Suffers Third-Round TKO Loss
Sean Strickland

Gets Back In The Win Column
Kyle Pitts Sr.

Falcons Planning to Use Franchise Tag on Kyle Pitts Sr.
Geoff Neal

Suffers Back-To-Back Knockout Losses
Uros Medic

Shines At UFC Houston
Dan Ige

Gets Finished For The First Time In His Career
Melquizael Costa

Extends His Win Streak To Six
NASCAR

Bubba Wallace Falls Short of Victory at EchoPark Speedway
Carson Hocevar

Rallies to Fourth At EchoPark Speedway After Early Struggles
Ross Chastain

Finishes Third At EchoPark Speedway
Chase Briscoe

Scores First Career Top-Five Finish at EchoPark Speedway
Tyler Reddick

Nabs His Second Win of the Season At EchoPark Speedway
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF