🖥 TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Daily Fantasy Football Lineup Picks (Week 16): NFL DFS Advice

RotoBallers, welcome to Week 16 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 16 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 16!

 

DraftKings Quarterbacks - Week 16 DFS Picks

Matthew Stafford - DET @ CIN (DK - $6,200)

Stafford is looking like one of the better options at quarterback this week for a number of reasons. First off, the Lions still have something to play for, so he will be doing all he can to get the win. We know he has multi touchdown upside, as he has done nine times this season. Stafford has put up 17 or more DraftKings points in seven of his last nine games, and has shown to be super consistent. He makes a great play in any format this week, as he is up against the Bengals who have the 18th DVOA against the pass.

Cam Newton - CAR vs TB (DK - $6,800)

Newton has scored 15 or more DraftKings points in six straight games, and is up against one of the worst defenses in the league. He is playing the Buccaneers, who have the 29th DVOA against the pass, and the 21st DVOA against the run. This is a prime spot for him, and he has shown his rushing upside in recent weeks. He has 50 or more rushing yards in five of his last six games, bringing plenty of tournament upside with him.

 

DraftKings Running Backs - Week 16 DFS Picks

Kenyan Drake - MIA @ KC (DK - $7,100)

Drake is up against the Chiefs, who have the 31st DVOA against the run, putting him in a great spot this week. Over the past four week, Drake has 80% of the Dolphins rushing attempts, which means he is their lead back and will be in the game regardless of the situation. The game script isn't saying they will be in this game, as they are a 10 point underdog, but if they want a shot in this game, they will run the ball a lot and slow the game down, putting Drake in a spot to succeed.

Christian McCaffrey - CAR vs TB (DK - $6,400)

McCaffrey brings a dual threat out of the backfield, as he has seen 22 targets over his last four games. He isn't a pure running back and has only gone for a season high of 66 yards this season, but saw double digit rushing attempts last week for the first time since Week 9. This is an encouraging sign, which should benefit him this week, since his opponent has a very bad defense. He is up against the Buccaneers, who have the 21st DOVA against the pass, and the 23rd DVOA against running backs in the passing game. Prime match up for him, and the Panthers are still in a spot where they need to win games, so they won't easy off the gas.

 

DraftKings Wide Receivers - Week 16 DFS Picks

Robert Woods - LAR @ TEN (DK - $6,500)

Woods is back from his injury, and last week he put six receptions 45 yards, and one touchdown. He is good mid range option who has some PPR upside against a Titans team who has the 24th DVOA against the pass. This puts him in a good spot, since the Rams still have something to play for, and will not be resting their starters. Woods has multi touchdown upside, which he has shown in the games before his injury.

Chris Godwin - TB @ CAR (DK - $3,000)

With DeSean Jackson being out of practice yet again on Thursday, Godwin is in a spot to see increased targets, as he did last week, after Jackson left the game early with the injury. Last week he ended with five receptions for 68 yards, for a total of 11.8 DraftKings points. He is also super cheap on DraftKings, so the savings he brings to your lineup will allow you to get up to the higher priced players.

 

DraftKings Tight End - Week 16 DFS Pick

Eric Ebron - DET @ CIN (DK - $3,700)

Everyone and their mother is talking about Antonio Gates this week as a tight end option, since he is so cheap, and will be seeing more targets now that Hunter Henry is done for the year. If you want another option at tight end, look at Ebron. he is up against the Bengals who have the 30th DVOA vs tight ends, and have suffered major losses on their defense. He has 15 receptions over his last two games, and with the Lions needing to win games to stay in the playoff picture, he will see plenty of snaps.

 

DraftKings Defense - Week 16 DFS Pick

Detroit Lions @ Cincinnati Bengals

The Lions are in a spot where they need to win games to try and make the playoffs, so look to their defense to step up against a weak Bengals team. Last week against the Vikings we saw that the Bengals have all but given up on the season, making them a nice target this week. The Lions have seven sacks over their last four games, along with five interceptions in that span. They have turnover potential against this weak Bengals offense.

 

More Weekly DFS Analysis





POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Seth Jarvis

to Be "Out for a While"
Phillip Danault

Rejoins Canadiens for Draft Pick
Mason Marchment

Blue Jackets Acquire Mason Marchment
Ja Morant

to Miss Second Straight Game Saturday
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
RJ Barrett

to Remain Out Saturday
Jakob Poeltl

Facing Another Potential Absence Saturday
Jerami Grant

Picks Up Questionable Tag
Deandre Ayton

to Miss Matchup Against Clippers Saturday
Lauri Markkanen

Unlikely to Play Saturday
Klay Thompson

Iffy for Saturday
Anthony Davis

Expected to Play Saturday
James Harden

Available Saturday
Domantas Sabonis

to Miss 4-5 More Weeks
Anthony Edwards

Returns Without Minutes Restriction Friday
Zach Collins

Upgraded to Available Friday
Tre Jones

Available With Minutes Restriction
Ayo Dosunmu

Returns From Three-Game Absence
Kasparas Jakucionis

Makes First Career Start Friday
Davion Mitchell

Ruled Out Friday
Craig Porter Jr.

Skips Friday's Game
Sam Hauser

Available Versus Heat
Shane Baz

Orioles Acquire Shane Baz From the Rays
Andrew Wiggins

Misses Friday's Action
Donovan Mitchell

Unavailable Friday Due to Illness
Jonathan Marchessault

Out Day-to-Day
Tristan Jarry

Oilers Place Tristan Jarry on Injured Reserve
Patrick Kane

to Remain Out Saturday
Shea Theodore

Considered Week-to-Week
Karl-Anthony Towns

& Josh Hart Active Friday Night
Jack Eichel

to Miss at Least Two More Games
Davante Adams

Likely Won't Play in Week 17
Jordan Martinook

Misses Friday's Contest
Evan Rodrigues

Available Against Hurricanes
Tyler Seguin

Undergoes Surgery, to Be Re-Evaluated After Olympics
Marvin Harrison Jr.

Listed as Questionable for Week 16
Drake London

Expected to Play Sunday
Tee Higgins

Questionable to Play in Week 16
Michael Carter

Will Start at RB in Week 16
Dalton Kincaid

Will Practice on Friday, Expected to Play on Sunday
Garrett Wilson

Shelved for Remainder of 2025
CFB

Darian Mensah Returning to Duke Next Season
CFB

Josh Hoover Linked to Indiana in Transfer Portal
CFB

Arch Manning Agrees to Reduced Compensation for 2026 Season
Zach Werenski

Enjoys Second Consecutive Multi-Goal Game
Logan Thompson

Collects Second Shutout of the Season
Linus Ullmark

Blanks Penguins Thursday
Tyson Kozak

Hurt Against Flyers
Conor Timmins

to Miss 6-8 Weeks With Broken Leg
Tristan Jarry

Sustains Lower-Body Injury Versus Bruins
Anthony Cirelli

Injured in Thursday's Loss
Kenneth Walker III

Breaks Off Long Touchdown in Comeback Win vs. Rams
Matthew Stafford

Racks Up Highest Yardage Total in Over a Decade
Puka Nacua

Delivers Career-Best Performance on Thursday Night Football
Michael King

Padres Bring Michael King Back on Three-Year Deal
Logan Webb

Will Pitch for Team USA in World Baseball Classic
Tarik Skubal

Joins Team USA for World Baseball Classic
Jakobi Meyers

Jaguars Agree to Three-Year Extension With Jakobi Meyers
Davante Adams

Officially Out on Thursday Night
Michael Kesselring

Available After 14-Game Absence
Peyton Krebs

Good to Go Thursday
Jake Bean

Set for Surgery, Out Indefinitely
Devin Neal

Placed on Injured Reserve, Will Not Return in 2025
CFB

Will Muschamp Becoming Next Texas Defensive Coordinator
Christian Watson

Questionable for Week 16
Josh Jacobs

Listed as Questionable for Saturday Night
T.J. Watt

Unlikely to Play in Week 16
D'Andre Swift

Questionable to Face the Packers
Rome Odunze

Ruled Out for Week 16
Jawhar Jordan

Could be in for Significant Workload Against Raiders
Rome Odunze

Expected to Miss Third Straight Game
CFB

Beau Pribula Set to Enter Transfer Portal
Josh Jacobs

Expected to Play in Week 16
Bo Bichette

Willing to Make the Move to Second Base
CFB

Jeremiyah Love Officially Heading to NFL Draft
CFB

Jake Merklinger Leaving Tennessee for Transfer Portal
Mike Trout

Angels Open to Mike Trout Playing Center Field in 2026
CFB

Kansas State's Jayce Brown Intends to Transfer
CFB

Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
Justin Crawford

Phillies Planning to Start Justin Crawford in Center Field
CFB

Jayden Maiava Signs New Deal to Return to USC
CFB

Aidan Mizell Won't Return to Florida, Entering Transfer Portal
CFB

East Carolina Targeting Jordan Davis as Next Offensive Coordinator
CFB

Michigan QB Jadyn Davis Set to Enter Transfer Portal
CFB

Travis Williams Joining Texas A&M Defensive Staff
CFB

Dylan Raiola Entering His Name into Transfer Portal
CFB

Cincinnati's Brendan Sorsby Plans to Transfer When Portal Opens
Adolis García

Adolis Garcia, Phillies Finalizing One-Year Deal on Monday
Brandon Royval

Suffers First-Round TKO Loss
CFB

Baylor, LSU, Miami Among Potential Suitors for DJ Lagway
CFB

Aidan Chiles Will Enter Transfer Portal
Manel Kape

Shines At UFC Vegas 112
Kevin Vallejos

Gets Second-Round Knockout Win
Giga Chikadze

Suffers His First Career Knockout Loss
CFB

Quarterback DJ Lagway Entering Transfer Portal
Cesar Almeida

Gets Dominated
Cezary Oleksiejczuk

Wins Sixth Fight In A Row
Morgan Charrière

Morgan Charriere Suffers First-Round Knockout Loss
Melquizael Costa

Gets First-Round Knockout Win
Marcus Buchecha

Still Winless In The UFC
Kennedy Nzechukwu

And Marcus Buchecha Fight To Draw
Lance Gibson jr

Lance Gibson Jr. Drops Decision In His UFC Debut
King Green

Gets Back In The Win Column
Kenley Jansen

Agrees to One-Year Deal With Tigers
Merrill Kelly

Returns to Diamondbacks on Two-Year Deal

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP