X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

DraftKings Daily Fantasy Football Lineup Picks (Week 16): NFL DFS Advice

RotoBallers, welcome to Week 16 of the daily fantasy football season. In this column, you will find my recommended DraftKings DFS Lineup Picks to target for Week 16 of the NFL season.

The goal is to identify players to start on DraftKings this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the DraftKings price.

Let's find some DFS lineup sleepers, and win on DraftKings. Good luck in Week 16!

 

DraftKings Quarterbacks - Week 16 DFS Picks

Matthew Stafford - DET @ CIN (DK - $6,200)

Stafford is looking like one of the better options at quarterback this week for a number of reasons. First off, the Lions still have something to play for, so he will be doing all he can to get the win. We know he has multi touchdown upside, as he has done nine times this season. Stafford has put up 17 or more DraftKings points in seven of his last nine games, and has shown to be super consistent. He makes a great play in any format this week, as he is up against the Bengals who have the 18th DVOA against the pass.

Cam Newton - CAR vs TB (DK - $6,800)

Newton has scored 15 or more DraftKings points in six straight games, and is up against one of the worst defenses in the league. He is playing the Buccaneers, who have the 29th DVOA against the pass, and the 21st DVOA against the run. This is a prime spot for him, and he has shown his rushing upside in recent weeks. He has 50 or more rushing yards in five of his last six games, bringing plenty of tournament upside with him.

 

DraftKings Running Backs - Week 16 DFS Picks

Kenyan Drake - MIA @ KC (DK - $7,100)

Drake is up against the Chiefs, who have the 31st DVOA against the run, putting him in a great spot this week. Over the past four week, Drake has 80% of the Dolphins rushing attempts, which means he is their lead back and will be in the game regardless of the situation. The game script isn't saying they will be in this game, as they are a 10 point underdog, but if they want a shot in this game, they will run the ball a lot and slow the game down, putting Drake in a spot to succeed.

Christian McCaffrey - CAR vs TB (DK - $6,400)

McCaffrey brings a dual threat out of the backfield, as he has seen 22 targets over his last four games. He isn't a pure running back and has only gone for a season high of 66 yards this season, but saw double digit rushing attempts last week for the first time since Week 9. This is an encouraging sign, which should benefit him this week, since his opponent has a very bad defense. He is up against the Buccaneers, who have the 21st DOVA against the pass, and the 23rd DVOA against running backs in the passing game. Prime match up for him, and the Panthers are still in a spot where they need to win games, so they won't easy off the gas.

 

DraftKings Wide Receivers - Week 16 DFS Picks

Robert Woods - LAR @ TEN (DK - $6,500)

Woods is back from his injury, and last week he put six receptions 45 yards, and one touchdown. He is good mid range option who has some PPR upside against a Titans team who has the 24th DVOA against the pass. This puts him in a good spot, since the Rams still have something to play for, and will not be resting their starters. Woods has multi touchdown upside, which he has shown in the games before his injury.

Chris Godwin - TB @ CAR (DK - $3,000)

With DeSean Jackson being out of practice yet again on Thursday, Godwin is in a spot to see increased targets, as he did last week, after Jackson left the game early with the injury. Last week he ended with five receptions for 68 yards, for a total of 11.8 DraftKings points. He is also super cheap on DraftKings, so the savings he brings to your lineup will allow you to get up to the higher priced players.

 

DraftKings Tight End - Week 16 DFS Pick

Eric Ebron - DET @ CIN (DK - $3,700)

Everyone and their mother is talking about Antonio Gates this week as a tight end option, since he is so cheap, and will be seeing more targets now that Hunter Henry is done for the year. If you want another option at tight end, look at Ebron. he is up against the Bengals who have the 30th DVOA vs tight ends, and have suffered major losses on their defense. He has 15 receptions over his last two games, and with the Lions needing to win games to stay in the playoff picture, he will see plenty of snaps.

 

DraftKings Defense - Week 16 DFS Pick

Detroit Lions @ Cincinnati Bengals

The Lions are in a spot where they need to win games to try and make the playoffs, so look to their defense to step up against a weak Bengals team. Last week against the Vikings we saw that the Bengals have all but given up on the season, making them a nice target this week. The Lions have seven sacks over their last four games, along with five interceptions in that span. They have turnover potential against this weak Bengals offense.

 

More Weekly DFS Analysis





REAL-TIME FANTASY NEWS

Marcus Foligno

Available Against Panthers
Jaylen Brown

Considered Questionable for Friday
Tony DeAngelo

Unavailable Thursday
Anthony Mantha

Good to Go Thursday
Paul Skenes

Greeted Harshly by Mets on Opening Day
Thomas Chabot

Out 4-8 Weeks After Surgery
Jalen Suggs

Available on Thursday
Robert Thomas

Sits Out Thursday's Action
Tyler Toffoli

a Game-Time Call Thursday
Artturi Lehkonen

Returns to Action Thursday
Daniel Gafford

Unavailable for Friday
Brandon Lowe

Hits Two Home Runs on Opening Day
Buffalo Bills

Bills Sign Receiver Trent Sherfield
Immanuel Quickley

Ruled Out for Friday
Jaden Ivey

Shut Down for the Rest of the Season
Jalen Smith

Sidelined for Remainder of Season
Ketel Marte

Active, Leading Off on Opening Day
Tyler Goodson

Falcons Sign Tyler Goodson for Running Back Depth
Myles Garrett

Browns Won't Trade Myles Garrett
Kevin McGonigle

Batting Sixth in MLB Debut
Jeremy Peña

Jeremy Pena Not in the Lineup on Opening Day
Jonathan Greenard

Colts Interested in Jonathan Greenard
JJ Wetherholt

Batting Leadoff in MLB Debut
Micah Parsons

Expected to Miss First Three or Four Games of 2026
Breece Hall

Still a Chance Breece Hall Plays 2026 on Franchise Tag
Myles Garrett

Browns Modify Myles Garrett's Contract
Kyle Pitts Sr.

Remains a Risky Tight End Option Despite 2025 Breakout
Dalton Schultz

Upside Remains Limited Despite Resurgent 2025 Production
Kimani Vidal

Could Be Sliding Down the Running Back Depth Chart in Los Angeles
Juwan Johnson

Can Juwan Johnson Repeat Steady 2025 Production in 2026?
Jackson Chourio

Placed on Injured List with Fractured Hand
Francisco Lindor

Officially Starting on Opening Day
Tank Dell

Can Tank Dell Re-Establish His Career Coming Off His Serious Injury?
Chuba Hubbard

Has Chuba Hubbard Reclaimed the RB1 Role in Carolina?
Keegan Murray

Cleared for Basketball Activities
Killian Hayes

Uncertain for Thursday
Precious Achiuwa

Questionable Thursday
Jalen Suggs

Could Miss Third Consecutive Game
Anthony Black

Misses 11th Straight Game
Franz Wagner

Remains Out Thursday
Anthony Edwards

Could Return Saturday
Mika Zibanejad

Pots Two Goals Versus Toronto
Pavel Zacha

Adds Two More Points Against Buffalo
Jordan Addison

in Line for 2026 Resurgence with Improved Quarterback Play?
Landry Shamet

to Remain Out Thursday
Gunnar Helm

Appears Well-Positioned for 2026 Breakout
Vít Krejčí

Vit Krejci Misses Sixth Straight Game
Peyton Watson

Good to Go Wednesday
Dalton Kincaid

Facing Durability and Usage Questions Heading into 2026
Aaron Gordon

Misses Second Leg of Back-to-Back
Jakob Poeltl

Cleared to Play Against Clippers
Colston Loveland

Poised for Superstar Breakout in 2026?
Immanuel Quickley

Won't Play Wednesday
Brandon Ingram

Active Against Clippers
Khalil Shakir

Could See His Role in Buffalo Shrink in 2026
Myles Turner

Won't Play Against Trail Blazers
Christian Watson

Is Christian Watson's Breakout Season Coming in 2026?
Pat Freiermuth

Should Have More Volume, but QB Situation Still a Mystery
Nicolas Roy

to Be Out For "a Little Bit"
Anton Lundell

Likely Out for Rest of Regular Season
Anthony Mantha

Day-to-Day With Lower-Body Injury
Evgeni Malkin

to Remain Out Thursday
Mattias Samuelsson

a Game-Time Call Wednesday
Jonathan Quick

Remains Unavailable Wednesday
Victor Hedman

Takes Leave of Absence
Jake Bates

Lions Officially Re-Sign Jake Bates
Sean Murphy

Lands on 10-Day Injured List
Bryce Miller

Placed on 15-Day Injured List With Oblique Strain
Lars Nootbaar

Will Begin the Season on 60-Day Injured List
Jackson Holliday

Placed on 10-Day Injured List
Jeremy Peña

Jeremy Pena on the Astros Opening Day Roster
Blake Snell

Dodgers Place Blake Snell on 15-Day Injured List
John Carlson

Sets Up Three Goals Tuesday Night
Joel Hofer

Picks Up Sixth Shutout of the Season
John Tavares

Records Three Assists in Tuesday's Win
NJ

Arseni Gritsyuk Scheduled for Imaging Wednesday
Tony DeAngelo

Suffers Lower-Body Injury Tuesday
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Kirby Yates

Angels Place Kirby Yates on 15-Day Injured List
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Nick Lodolo

Will Open 2026 on the Injured List Due to Finger Ailment
Pete Crow-Armstrong

Agrees to Six-Year, $115 Million Extension With the Cubs
Francisco Lindor

Likely to be Ready for Opening Day
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Roki Sasaki

to Stick in Rotation Despite Spring Struggles
Kevin McGonigle

Makes Tigers Opening Day Roster
Scottie Scheffler

Withdraws From Texas Children's Houston Open
Ryan Pepiot

Placed on Injured List to Open the Season
Luke Clanton

Might Have a Problem in Houston
Sam Stevens

Happy to See Houston This Week
Keith Mitchell

Tries to Rebound After The Players Championship
Will Zalatoris

Returning This Week at Houston
Wyndham Clark

Trending in the Wrong Direction Heading to Houston
Shane Lowry

Seeking Better Luck in Houston This Weekend
Kurt Kitayama

Poised to Bounce Back at the Houston Open
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Iwo Baraniewski

Delivers 28-Second TKO
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Tyler Reddick

the Clear Favorite at Darlington
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
William Byron

Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
Chase Elliott

Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
Joey Logano

May Not Have the Speed to Warrant A Darlington DFS Lineup Spot
Ross Chastain

Should DFS Players Trust Ross Chastain at Darlington?
Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF