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College Football Betting Expert Picks for Week Twelve (11/21/2020)

Our CFB betting picks, analysis and top recommendations for Week 12. Every week, Nick reviews some of the best bets and wagers for the college football slate.

In Week Eleven, our fortunes continued with the fourth consecutive 3-0 week. Heading into the final weekend of games before Thanksgiving, the recent performance leaves us with much to be thankful for.

In the early noon game this past weekend, Miami managed to hold off the Virginia Tech Hokies as a 2.5-point underdog. At 3:00pm, the UTSA Roadrunners then provided win #2 with an easy rout of their in-state rivals at UTEP. In the late game, Oregon overcame a sluggish start to overcome a young, but impressive Washington State squad. This 12-0 run over the past four weeks improves the season-long record to 22-8.

Week Twelve's list of games should have bettors licking their chops with the amount of action available. Here are some betting picks to follow along with as you enjoy another college football Saturday.

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Clemson at Florida State (+35.5)

O/U: 63

Coach Dabo Swinney's Clemson Tigers will certainly be on a mission to pursue any style points that they can rack up before the anticipated ACC Championship rematch with Notre Dame on December 19. Star quarterback Trevor Lawrence, who should start looking for apartments in New York pretty soon, is returning after a two week absence caused by a positive COVID-19 test. Freshman DJ Uiagalelei stepped in admirably against Notre Dame and Boston College, causing Clemson fans to breathe a sigh of relief for when the time comes that Lawrence departs for the NFL. With Lawrence and Travis Etienne - the ACC's all-time rushing leader - the Clemson offense has hummed to the tune of 40.4 points per game. With a win on Saturday, Trevor Lawrence will tie Rodney Williams, Tajh Boyd, and Deshaun Watson for the record for the most career wins as a starting quarterback at Clemson.

The 2020 season has been an unmitigated disaster for first-year head coach Mike Norvell in Tallahassee, Florida. The team just received word that defensive tackle Marvin Wilson, who is likely a top NFL draft pick in the spring, will miss the remainder of the season with an injury. Additionally, star receiver Tamorrion Terry left the team to begin preparing for the draft, and former starting quarterback James Blackman announced his intention to transfer. 

The talent disparity between these two teams is vast, and expecting Clemson to put up a flurry of points is expected. However, expecting Florida State to be kept off the board is unreasonable with the dual-threat quarterback Jordan Travis leading the way. The Clemson defense has given up 21 points or more in each of its last three games, and if Florida State can get at least 2 touchdowns, it will be difficult for Clemson to cover such a large spread.

Pick: Florida State +35.5

Georgia State at South Alabama (+3.5)

O/U: 58.5

The Georgia State Panthers put quite a scare into the Appalachian State Mountaineers last week in Boone, North Carolina, but were unable to hold onto the close upset opportunity. Entering the game with a mediocre 3-4 record, the Panthers have had a few opportunities slip through their fingers, including the 4-point loss to Appalachian State and a 3-point loss to Louisiana (Lafayette). On offense, freshman quarterback Cornelius Brown IV has had a strong campaign (1,340 passing yards, 13 touchdowns, 5 interceptions) and looks to have a bright future in Atlanta. Brown's top target this year has been Sam Pinckney, aided by junior receiver Cornelious McCoy. The offense averages 33.3 points per game, and should have no problem putting up a flurry of points in Mobile. Surprisingly, Georgia State has never won in any of the 3 matchups against South Alabama on the road, while winning 4 of 5 at home.

The South Alabama Jaguars are chasing their first .500 or better season since 2013. Success is not synonymous with the Jaguars program, something that head coach Steve Campbell is hoping to change. With wins over Southern Miss, Texas State, and Louisiana-Monroe, the team took advantage of the "low-hanging fruit" on the schedule, and was competitive in losses to Tulane and Georgia Southern. Sophomore quarterback Desmond Trotter, when healthy, has paced the team on offense with his ability to pass with efficiency (9 touchdowns to 3 interceptions) and take off and run when nothing is there. Trotter's top target is Jalen Tolbert, who had a major breakout early in the season and has 44 catches and 5 touchdowns. The Jaguars offense has stalled at times, averaging only 20.9 points per game, as result of an anemic rushing attack.

This Sun Belt clash should be an exciting tilt between two teams that are clearly on the rise in the conference. Georgia State has the built-in recruiting advantage in the Atlanta metro area, and in recent years that has shown itself with more consistent on-field play. While the Trotter-to-Tolbert connection does show plenty of promise, there are too many holes throughout the rest of the roster to trust the Jaguars at this point in time.

Pick: Georgia State -3.5

#20 Southern California (USC) at Utah (+3)

O/U: 57.5

USC has opened its season with a pair of closer than expected wins over the Arizona schools, causing some concern. The Trojans' offense has been sharp, spearheaded by sophomore quarterback Kedon Slovis, and his two star receivers Amon-Ra St. Brown and Tyler Vaughns, all of whom will be playing on Sundays. When it comes to night games, USC thrives with an all-time 72.6% winning percentage in games played 5pm or later. In Utah's banner season last year, USC was the only regular season opponent to vanquish the Utes behind their backup quarterback Matt Fink.

The Utah Utes have yet to play this season, with their first two games being postponed due to the Coronavirus. Finally, things look to be trending in the positive (pun intended) direction, as they aim for their opener this weekend. Long-time coach Kyle Whittingham had arguably his most talented team last season, and was probably a win in the Pac-12 championship game away from Utah's first appearance in the College Football Playoff. Gone are quarterback Tyler Huntley, running back Zack Moss, and nine defensive starters (five of whom were drafted in the 2020 NFL draft). The new signal caller will be one of the triumvirate atop the depth chart - former walk-on Drew Lisk, South Carolina graduate transfer Jake Bentley, and highly-touted sophomore Cameron Rising. With an entirely new defense and a new quarterback, there may be an adjustment period in Salt Lake City.

Utah is still scrambling with contact tracing and some lingering positive COVID-19 student-athletes, which might cause nearly 20% of the roster to be unavailable on Saturday. With a few games under their belt so far, USC will have the clear edge and Slovis will try to make his mark early on against a young, new and unproven Utah defense.

Pick: USC -3




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REAL-TIME FANTASY NEWS

Davante Adams

Not Expected to Play in Week 18
Stephon Castle

Active on Wednesday
Tyler Kolek

Elevated to Available on Wednesday
Tari Eason

Questionable Versus Brooklyn
Tobias Harris

Not Expected to Suit Up on Thursday
Ariel Hukporti

Available For Wednesday
Alperen Sengün

Alperen Sengun Questionable Versus Brooklyn
Mason Plumlee

Undergoes Groin Surgery
Zach Collins

Out at Least 10 More Days
Jerami Grant

Unavailable Again on Wednesday
Geno Smith

Won't Play in Week 18
Aaron Rodgers

Considering Playing Beyond 2025?
Sean Monahan

Sits Out Wednesday's Game
Zach Werenski

Misses Fourth Straight Game Wednesday
Dougie Hamilton

Questionable Wednesday
Radko Gudas

Expected to Remain Out Wednesday
Stefon Diggs

Expected to Play in Week 18
Ilya Lyubushkin

Back From One-Game Absence Wednesday
Alex Lyon

to Miss "Bit of Time"
Erik Cernak

Rejoins Lightning Lineup Wednesday
Christian McCaffrey

Trending to Play in Week 18
Kon Knueppel

To Make Return For Charlotte On Wednesday, In Starting Lineup
Jalen Hurts

Eagles Expected to Rest Jalen Hurts, Most Starters in Week 18
George Kittle

49ers Will be "Very Surprised" if George Kittle Doesn't Play on Saturday
Marvin Harrison Jr.

Ruled Out for Regular-Season Finale
CFB

Lane Kiffin Interested in Sam Leavitt, Brendan Sorsby at LSU
Shakir Mukhamadullin

Questionable Wednesday
Adam Gaudette

Unavailable Wednesday
Darcy Kuemper

Activated From Injured Reserve
Alex Lyon

Nursing Lower-Body Injury
William Karlsson

to Miss Olympics
Jack Eichel

a Game-Time Decision Wednesday
Jason Dickinson

Hurt Versus Islanders
Mitchell Robinson

Sits Out Wednesday's Game
Grayson Allen

Listed as Doubtful Wednesday
Mason Plumlee

Ryan Kalkbrenner, Mason Plumlee Remain Out Wednesday
Kon Knueppel

Likely to Return Wednesday
Miles Bridges

Listed as Questionable Wednesday
Isaiah Hartenstein

Misses Second Straight Game
Devin Vassell

Ruled Out for Wednesday
Stephon Castle

Iffy for Wednesday
Josh Giddey

Sidelined "at Least a Few Weeks"
Desmond Bane

Might Miss Wednesday's Game in Indiana
Jalen Suggs

on the Injury Report Again for Wednesday Night
Connor Dewar

Available Tuesday
TOR

Chris Tanev to Miss Time With Lower-Body Injury
Dakota Joshua

Out With Kidney Problem
MON

Samuel Montembeault Returns to Canadiens Crease
Erik Karlsson

Good to Go Tuesday
William Nylander

Misses Second Consecutive Game
Auston Matthews

a Game-Time Call Tuesday
CFB

Deuce Knight Officially Entering Transfer Portal
CFB

Kewan Lacy Expected to Be Full-Go Against Georgia
Stefon Diggs

Facing Strangulation, Assault Charges
CFB

Chip Kelly Named Northwestern Offensive Coordinator
Riley Leonard

Will Start Against the Texans
Bijan Robinson

Explodes for 229 Total Yards, Two Touchdowns on Monday Night
Davante Adams

Officially Out on Monday Night
Drake London

Active Against Rams
Justin Herbert

Won't Face Broncos in Week 18
Marcus Mariota

Considered "a Stretch" to Play in Week 18
Geno Smith

Dealing With Significant Ankle Injury
Dak Prescott

Will Play in Week 18
Lamar Jackson

Week 18 Status "to be Determined"
Joe Mixon

Won't Return This Season
T.J. Watt

a Long Shot to Play in Week 18?
CFB

Penn State Working to Hire D'Anton Lynn as Next Defensive Coordinator
Joe Burrow

Will Play in Week 18 Against the Browns
CFB

Omar Cooper Expected to be Full-Go for Rose Bowl
CFB

Marcus Freeman Staying with Notre Dame for 2026 Season
CFB

Star Wideout Cam Coleman Entering Transfer Portal
CFB

Jay Hill Expected to be Next Michigan Defensive Coordinator
CFB

Michigan Targeting Kyle Whittingham as Next Head Coach
CFB

Texas Leading Rusher Quintrevion Wisner Set to Transfer

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