👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


Break The Slate: NFL DFS DraftKings Lineup Picks - Week 15 (Main Slate)

Lamar Jackson - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Joe Nicely's DraftKings NFL DFS picks and lineup sleepers for Week 15. His top daily fantasy football recommendations to target for DraftKings DFS contests.

Hi there, RotoBallers, and welcome back to Break The Slate! If you read this article regularly, then you know what we're about here, but if you are a new reader, let me quickly summarize our goals with this article. We'll spend each week discussing a few plays at each position for the DraftKings main slate that can add tournament-winning upside and/or juicy value to our NFL DFS rosters. I'll highlight my favorite players and breakdown my reasoning behind them.

I try to update the article on Saturdays to reflect any significant injuries or late-breaking news, as the landscape of the slate can change quickly in the NFL, and I definitely recommend you checking those out. Week 15 is shaping up to be a fun slate and I'm excited to dig in! Remember, the NFL is ever-evolving from week to week, which gives us an opportunity to apply what we've learned on the next slate.

These DraftKings lineup recommendations are based on matchups, projected ownership, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home-field advantage, and more. There are quite a few great plays available, so read on to find out which players are the best for Week 15. Be sure to also check out our weekly FanDuel DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Good luck with your DraftKings DFS lineups, let's Break The Slate together!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DraftKings DFS Quarterbacks - Week 15 Picks

Patrick Mahomes - KC @ NO ($7,900)

I rarely write up Mahomes because I feel it goes without saying that he’s an elite option that’s basically matchup proof, but nevertheless, here’s your reminder: 

PATRICK MAHOMES CAN ALWAYS BREAK THE SLATE!

Lamar Jackson - JAX @ BAL ($7,500)

The last time I was heavily invested in Lamar Jackson was Week 5 against the Bengals when he posted 14.5 DK Points. Jackson didn’t look comfortable to me in that game, and as a result, I’ve basically laid off ever since, as the NFL’s reigning MVP has failed to replicate his play from last season. However, Jackson has looked better over Baltimore’s last two, with his rushing output noticeably spiking. He’s ran for 218 yards and three TDs since Week 13, the type of production that was commonplace last year, but has been difficult to come by this season.

He brings that trending production into a true smash spot against Jacksonville this week. This Jags defense is basically horrible in all aspects, ranking 30th in the NFL in yards allowed per carry and 28th in yards allowed per pass. Jackson appears to be getting his groove back and should have his way with this defense.

Jalen Hurts - PHI @ ARI ($5,900)

I waffled back and forth about whether to include Jalen Hurts in this article last week. I loved the price ($5.1k), but feared the situation (first career start against a good Saints Defense). We can fire Hurts up with a little more confidence this week, as we know more about what we're getting with the Philly rookie. The most notable takeaway from his performance against New Orleans was his 18 rushing attempts - a ridiculously-high total for a QB - that produced 106 yards on the ground. While we can't count on quite that much volume on a weekly basis, Hurts' rushing ability is obviously - at least initially - going to be a prominent tool in his toolbox. His work running the ball significantly raises his DFS floor and he's set to square off against an Arizona defense that's allowing 5.45 yards per carry to opposing QBs, the fourth-highest mark in the NFL. Even though DK has bumped his price from $5.1k to $5.9k, you can argue that he remains underpriced due to his extensive role on the ground.

SATURDAY UPDATE: 

The big news at the QB position is Drew Brees' surprising availability for the Saints. I would make the argument that Brees getting the start makes Patrick Mahomes an even better play this week (NO is more likely to put up points and stay in the game with Brees at the helm of the offense). I'm fairly locked in with the highlighted QB plays personally, but Chicago's Mitch Trubisky is a viable (though gag-inducing) value option.

 

DraftKings DFS Running Backs - Week 15 Picks

Derrick Henry - DET @ TEN ($9,500)

All Derrick Henry wanted for Christmas was to play Jacksonville and Detroit in back-to-back weeks. I guess The King gets what The King wants, as Henry is set to face the hapless Lions fresh off an absolute demolition of the Jags last week. The Titans back rumbled for 215 yards and 2 TDs on 26 carries last week, and we can assume it will be more of the same this week against a Lions Defense that - somehow - grades out even worse against the run than Jacksonville. Detroit has allowed the second-most DK Points in the NFL to the RB position and is relinquishing a MASSIVE 4.57 yards per carry to opposing rushers. This is the perfect storm, as Tennessee should be leading throughout in this one and will be very content to feed Henry the ball 25-plus times. 

Jonathan Taylor - HOU @ IND ($7,200)

If we could get a visual chart of the fantasy community’s opinion on Jonathan Taylor throughout the year, it would look like the Rocky Mountains. Everyone was in love with Taylor when the Colts drafted him in the second round of the NFL Draft. His prospects then really shot up when Indy’s incumbent RB, Marlon Mack, went down with a season-ending injury in Week 1. However, the rookie failed to do anything much with the opportunity, and appeared to lack burst and vision, as his fantasy stock plummeted. But a funny thing happened on the way to Taylor becoming Trent Richardson...he actually started producing around Week 11...when the Colts seemed to “recommit” to him by giving him 26 touches against Green Bay. Taylor has responded by posting DK Point totals of 15.4, 22.5, & 33.5 over his last three starts. 

We could argue that the production has been the result of three tremendous matchups, but Taylor once again draws a smash spot against Houston this week. The Texans are ridiculously bad against the run and are the only team in the NFL allowing over FIVE yards per carry this year. The only real concern here is that Nyheim Hines remains an effective back for the Colts and will likely continue to steal some work from Taylor. 

Cam Akers - NYJ @ LAR ($6,600)

At first glance, this feels like a tremendous spot for Cam Akers, a player that's starting to look like a superstar-in-the-making. However, after digging into it, I'm not as in love with Akers in this spot as some will be. The Jets are undoubtedly terrible, but perhaps their lone bright spot has been a defense that ranks eighth in the NFL in DVOA against the run. Yes, Akers has been given the keys to this backfield over the last two weeks, but we are dealing with a coach in Sean McVay that's been extremely unpredictable with his RB rotations, so it wouldn't be surprising to see Darrell Henderson mix in fairly heavily for the Rams if this game gets out of hand.

After reading those thoughts, it's fair if you're wondering, "Why are you recommending Cam Akers then?" Well, I do love Akers' talent level, as well as his receiving ability out of the backfield, which makes him a "very good, but maybe not as awesome as everyone else might think" play for me. This is also a tough slate for the RB position and - barring a late-week injury situation - there's very little to love as we go down the salary scale, so Akers is certainly a viable play that brings real upside to the table at $6.6k.

SATURDAY UPDATE: 

Drew Brees' availability really reverberates throughout several positions on this slate and Alvin Kamara is perhaps the biggest beneficiary of the news. Kamara's $7.4k price tag reflects his "expected performance with Taysom Hill at QB", which makes him very underpriced for what he should be able to do with Brees. Tampa's Ronald Jones isn't expected to play this week, which throws Leonard Fournette into the mix. Atlanta's run defense has been sneaky solid as of late - so this isn't the smash spot that it might appear to be - but we're pretty starved for value on this slate and Fournette is a viable salary saver at just $4.7k. Two injury situations I'll be keeping an eye on...Arizona's Chase Edmonds is Questionable and Kenyan Drake's value would jump if Edmonds can't go. Miami's backfield situation is also up in the air, as Myles Gaskin is still on the COVID list and Salvon Ahmed is Questionable but trending in the right direction. Ahmed would be a great value option if he's able to suit up.

 

DraftKings DFS Wide Receivers - Week 15 Picks

Tennessee Titans WRs - DET @ TEN

A.J. Brown  ($7,600) & Corey Davis ($5,800)

Sometimes you can't pick just one! There's so much to love about these Titans pass catchers this week against the Lions, as A.J. Brown brings legitimate slate-breaking upside to the table, while the resilient Corey Davis is a tremendous salary saver at just $5.8k. Detroit ranks dead last in the NFL in both yards per target (9.38) and catch-rate percentage (71.2% - the only team in the league allowing a catch percentage over 70%!) allowed to the WR position. Not only is this Lions secondary terrible, but they are also banged up, as both Desmond Trufant and Jeff Okudah are on IR.

The only drawback is that Detroit is also absolutely horrible against the run and the Titans have a guy by the name of Derrick Henry in the backfield. It's easy to envision Tennessee controlling this one throughout and just handing Henry the ball 30 times at the expense of Brown & Davis. However, betting on these high-upside pass catchers instead of Henry is a really interesting contrarian route that you can take in GPPs.

Brandon Aiyuk - SF @ DAL ($6,300) 

I highlighted Brandon Aiyuk in this article last week, but despite the risk of being redundant - and a $900 DK price increase - I’m still on the Niners rookie in Week 15. Aiyuk overcame a matchup that we knew was difficult against Washington last week to post 119 yards and 10 catches on 16 targets. It’s that volume - in addition to his talent level - that’s led him to an average of 21.74 DK Points per game over his last five starts. While last week’s matchup was a tough one, this week's isn't...as he’s in a true smash spot against the Dallas Cowboys. Not only is the Cowboys secondary currently banged up, they’ve been consistently bad throughout the season. Dallas ranks 25th in the NFL in DK Points allowed to the WR position and they are relinquishing a juicy average of 8.78 yards per target to opposing receivers.

T.Y. Hilton - HOU @ IND ($5,500)

It admittedly feels “point chasey” to go after TY Hilton this week - and we do have to think there will be some negative TD regression incoming at some point - however, the Colts veteran WR has a combination of price and matchup in Week 15 that’s almost impossible to ignore. Despite posting DK Point totals of 28.0 (against Houston) and 25.6 over Indy’s last two games, Hilton still sits at just $5.5k. He’ll also see one of the better matchups in football against a Texans secondary that has been routinely torched in the absence of Bradley Roby. Hilton himself lit them up for 110 yards and a TD on eight catches in Week 13, and Houston has allowed six opposing WRs to post 25 or more DK Points against them this year. There's a strong chance that "The Ghost" once again spooks Houston's struggling journeyman corner Vernon Hargreaves this week. 

 

DraftKings DFS Tight Ends - Week 15 Picks

Travis Kelce - KC @ NO ($8,000)

It's pretty simple...if Travis Kelce is playing on the Main Slate, he's going to be in consideration for me. Even though Kelce's price is all the way up to $8k, he's basically the only trustworthy option at the TE position. He heads into a Week 15 matchup against the Saints on the heels of back-to-back 30.6 DK Point performances (Kelce has eerily went for exactly 8/136/1 in EACH of his last two!) and like his KC teammates, Patrick Mahomes & Tyreek Hill, he's basically matchup proof.

Mark Andrews - JAX @ BAL ($5,500)

As of late, I've basically been deploying a "pay all the way up for Kelce or completely punt the TE position" strategy...but Mark Andrews is kinda the natural salary-saver pivot from Kelce, as he's a well-known player in a great matchup that's $2.5k cheaper. I noticed that Andrews' best DFS performance of the season was 22.8 DK Points against Cleveland in Week 1. That's roughly what Kelce averages per game, so make no mistake, saving the salary comes at a cost. That said, Andrews is in a great spot against Jacksonville, a defense that's terrible in every facet and has allowed 10 TDs to the TE position this season, which is the second-most in the NFL.



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Mason Taylor

Dynasty Value Takes a Hit for Now
Denny Hamlin

Earns the first Nashville Cup Series Victory of his Career on Sunday
Zachariah Branch

a Steal in the Second Round of Rookie Drafts?
Christopher Bell

Finishes as the Runner-Up at Nashville
Chase Briscoe

Earns First Career Podium Finish at Nashville
Ryan Blaney

Scores A Solid Top-10 Finish at Nashville
Eli Stowers

Worth Targeting Now Before Eventual Breakout?
Kyle Larson

Top-10 Streak at Nashville Ends after Late Flat Tire Spin
Germie Bernard

Expected to Require Some Patience in Dynasty Leagues
Denzel Boston

a First-Round Target in Dynasty Rookie Drafts
Bryce Young

Dynasty Value Impacted by Inconsistency
Jeremiyah Love

Can Jeremiyah Love Become an Instant Fantasy Contributor?
Odell Beckham Jr.

Giants Working Out JuJu Smith-Schuster and Braxton Berrios in Addition to Odell Beckham Jr.
Odell Beckham Jr.

Working Out for Giants
A.J. Brown

Could Be Dealt Within Next 24 Hours
Parker Washington

Set to Play "Most Important Role" of His Career in Jaguars Offense
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Wan'Dale Robinson

Dynasty Value May Have Peaked in 2025
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
Tyler Shough

Should Dynasty Managers Consider Selling High on Tyler Shough?
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Garrett Wilson

Dynasty Upside Remains High Despite Questionable Offensive Environment in New York
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Kenneth Gainwell

Carries Dynasty Sell-High Appeal After Breakout 2025 Campaign
Emeka Egbuka

Undervalued in Dynasty Formats After Underwhelming Close to 2025?
Trey Benson

a Dynasty Hold Despite Unfavorable Situation
Omar Cooper Jr.

a Long-Term Investment in the First Round of Rookie Drafts
Colston Loveland

Just How High is Colston Loveland's Dynasty Ceiling?
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Zay Flowers

A New-Look Offense in Baltimore Could Impact Zay Flowers' Dynasty Value
LeQuint Allen Jr.

a Dynasty Dart Throw with a Potential Path to Upside
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Chet Holmgren

Fails to Step Up in the Season Finale
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Kyrie Irving

Reports He's Nearing Full Strength in ACL Recovery
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Mitchell Robinson

Plans to Play in Game 1 After Finger Surgery
Ajay Mitchell

Ruled Out for Game 7
Jalen Williams

Unavailable in Decisive Game 7
NBA

Magic Finalizing Hire of Sean Sweeney as Head Coach
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
Jalen Williams

Limited in Game 6 Return
Jared McCain

Provides Bench Spark in Game 6 Loss
Shai Gilgeous-Alexander

Posts Lowest-Scoring Night of His MVP Season
De'Aaron Fox

Struggles From the Field Thursday
MLB

MLB Proposes Hard Salary Cap as Part of Next CBA
Kenley Jansen

Tigers Place Kenley Jansen on Injured List With Pelvic Inflammation
Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
CAR

Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
Russell Henley

a Top Option at Colonial
Harry Hall

Hoping Putter Carries Him at Colonial
Rickie Fowler

Looks to Regain Momentum at Colonial
Pierceson Coody

Looking to Stay Hot at Colonial
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF