👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

FanDuel NFL DFS Lineup Picks for Week 10 - Daily Fantasy Football

Dennis Clausen highlights the top FanDuel NFL DFS lineup picks for Week 10 of the 2021 season, and some value sleepers for your daily fantasy football rosters.

What a wild Week 9 it was. With so many players not only failing to meet projections but also falling well below, the scores throughout the DFS community weren't the prettiest by any means. Yet, it was likely a good day for those who turned to James Conner, Jonathan Taylor, Nick Chubb, or Joe Mixon as their preferred options. Additionally, we can't forget about Lamar Jackson or Justin Herbert's contributions, either, while also acknowledging the performance of the returning George Kittle, who had six receptions for 101 yards and a touchdown in his first game since suffering a calf injury back in Week 4. We also saw some wideouts come out of nowhere to make some noise, with Elijah Moore and Olamide Zaccheaus crushing their respective values.

Of course, things have certainly changed since the conclusion of Week 9, with the top story heading toward Sunday being the unfortunate incident involving Dalvin Cook, who is in danger of possibly missing time. Although that may not happen as early as the Vikings meeting against the Los Angeles Chargers, it's certainly a situation fantasy managers want to keep an eye on, mainly if Cook gets suspended. If that's the case, Alexander Mattison will automatically assume the role as the team's top back, and we all know what the 23-year-old is capable of when given a chance.

In this article, I will be providing you with my Week 10 daily fantasy football lineup picks for FanDuel’s “Main Slate.” These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Feel free to give me a follow on Twitter @DennisMClausen.

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

FanDuel Quarterbacks - Week 10 DFS Lineup Picks

Josh Allen, QB - vs. NYJ ($8,700)

We shouldn't be ready to give up on Allen, who surprisingly performed terribly during the improbable loss to the Jaguars. After he got off to a slow start against the Dolphins in Week 7, many had assumed that the bye would do him some good. However, that's not how things played out, as the former Wyoming Cowboy had one of the worst performances of his career against Jacksonville.

Nonetheless, Allen can help lessen the sting by turning things around against the Jets. Fortunately, he has a good chance, actually an excellent chance, of doing just that against a New York team that has struggled defensively, allowing 130 points combined against the Patriots, Bengals, and Colts over the last three weeks.

Dak Prescott, QB - vs. ATL ($8,100)

Prescott returned last Sunday against the Broncos after dealing with a calf injury that forced him to miss some time. Despite the possibility of being rusty, the veteran was still expected to have his way with the Denver defense. Yet, that didn't happen, and just like in Josh Allen's case, his output was a colossal disappointment. Still, he's allowed a free pass, primarily since he likely wasn't 100 percent, so we can put that disastrous outing behind him and move on to Atlanta.

Prescott stated that he has been working on his footwork during practice throughout the week, which was an issue against the Broncos. With that, he should regain some confidence, especially regarding planting his foot during throws, something he had a problem doing during the loss. To make things even more enticing, Vegas has the Cowboys as one of the top-scoring teams on the slate, so it's more likely than not he will bounce back against the Falcons.

Also Consider: Patrick Mahomes ($8,400), Justin Herbert ($8,000)

 

FanDuel Running Backs - Week 10 DFS Lineup Picks

James Conner, RB - vs. CAR ($7,000)

Kyler Murray and DeAndre Hopkins didn't suit up for the Week 9 showdown against the 49ers, and it was seemingly a foregone conclusion that the Cardinals would get smoked. Let's face it, Colt McCoy hasn't been the most reliable signal-caller through the years, and while Christian Kirk and Rondale Moore have had their moments of efficiency, not having an MVP candidate or a stud receiver in the lineup isn't ideal.

Yet, Arizona has arguably the best one-two punch out of the backfield in Conner and Chase Edmonds, so naturally, they were expected to serve as a crutch for McCoy when things got rough. Yet, things got even worse for the birds after Edmonds went down with a high-ankle sprain and didn't finish the game as a result. Luckily, Conner, who most believed was well past his prime, turned on the burners and carried the team on his back to a win.

The former Steeler was already playing well leading up to bout versus San Francisco, scoring at least once in five of his eight showings on the year. Yet, he surpassed expectations by finding the end zone three times in total while racking up nearly 100 rushing yards. He also caught all five of his targets for 77 yards. With Edmonds now out for the foreseeable future, Conner should get plenty of opportunities to produce against a shoddy Panthers defense, even if Murray and Hopkins can make it back.

D'Ernest Johnson, RB - @ NE ($5,400)

When we thought we'd seen the last of Johnson, here he is again, ready to occupy space in an abundance of DFS lineups. Yes, we'd love to believe we can get away with other options to go against the crowd. However, when considering his potential points total in relation to his value, we may not have any other choice than to keep him under consideration against New England.

Kareem Hunt remains out with a calf issue, and Nick Chubb has, you guessed it, COVID-19, so Johnson should be in line to handle the bulk of the work in Week 10. The 22-year-old was a menace against Denver during his only start of the season by racking up 146 yards and a touchdown off 22 carries. He also had a pair of receptions for 22 yards. It isn't unreasonable to believe he may see that same workload against the Patriots. Yet, even if he doesn't produce the way he did against the Broncos, the bargain opportunity certainly makes rolling with Johnson worth the risk.

Also Consider: Jonathan Taylor ($9,400), Austin Ekeler ($8,600), Dalvin Cook ($8,500), Darrel Williams ($6,000), Mark Ingram II ($5,500)

 

FanDuel Wide Receivers - Week 10 DFS Lineup Picks

Davante Adams, WR - vs. SEA ($8,700)

Adams wasn't available for Thursday Night Football versus Arizona in Week 8 after he was placed on the reserve/COVID-19 list. Yet, he made his return last Sunday against Kansas City, albeit he didn't have Aaron Rodgers throwing him the ball. With Rodgers out against the Chiefs because of a positive COVID-19 diagnosis, Jordan Love got the first start of his career.

Without a doubt, the absence of the reigning MVP signal-caller didn't do Adams any favors. He would finish with only 42 receiving yards, catching just six of his 14 looks from Love throughout the game. Fortunately, Rodgers is on track to play against the Seahawks. Still, even if Rodgers doesn't, Adams has plenty of room to produce against Seattle.

Tyreek Hill, WR - @ LV ($8,400)

Hill began the year by nearly compiling 200 yards against the Cleveland Browns. However, he hasn't been as consistent as most fantasy managers had expected him to be since then. Sure, he's had some good outings. Yet, he's had some bad ones as well.

Nonetheless, now is a good time for DFS enthusiasts to start believing in the 27-year-old. His rostering cost is super low. Also, Hill has played well versus the Raiders throughout his career by hauling in 43 catches for 635 yards and six total touchdowns. Although historical trends don't necessarily result in similar outcomes, everyone should be willing to take a chance on this one.

Also Consider: Cooper Kupp ($9,500), Justin Jefferson ($7,500), Diontae Johnson ($7,400), Keenan Allen ($7,200)

 

FanDuel Tight Ends - Week 10 DFS Lineup Picks

Darren Waller, TE - vs. KC ($7,000)

Las Vegas has had its share of ups and downs this year. While the team is playing better than most had anticipated, it's even more impressive that the Raiders have a winning record when you consider the organization parted ways with its head coach, Jon Gruden, and leading wideout, Henry Ruggs III.

Without Ruggs, it was expected that others would step up, and that's just what happened against the Giants. However, Waller remained the most involved by providing a source of comfort for Derek Carr. Overall, Waller received 11 looks from Carr, with the 29-year-old bringing in seven catches for a game-high 92 yards. It will be a battle of arguably the best tight ends in the league, as Waller and Travis Kelce will square off in an AFC West showdown. Fortunately for the former Georgia Tech Yellow Jacket, the Chiefs haven't played well on the defensive end all year. It's also expected that Waller will continue to get more than enough attention from Carr not only in Week 10 but for the remainder of the year.

Also Consider: Travis Kelce ($7,500)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Cole Hutson

Delivers Two Assists Saturday
Mikhail Sergachev

Ties Mammoth Record With Four Assists
Connor McDavid

Reclaims Scoring Lead With Three-Point Effort
Dmitri Voronkov

Unavailable Sunday
Aliaksei Protas

Suffers Upper-Body Injury Saturday Night
Ty Gibbs

Should Fantasy Players Roster Ty Gibbs At Martinsville?
Josh Anderson

Limited Due to Illness Saturday
Ryan Preece

Is A Solid DFS Option for Martinsville Lineups
Josh Berry

Could Josh Berry Pay Off for Tournament DFS Lineups At Martinsville?
NHL

Nathan Bastian Makes Early Exit Saturday
Carson Hocevar

May be Too Inconsistent to Start in Martinsville DFS Lineups
Dejounte Murray

Uncertain for Sunday
Austin Cindric

Is Austin Cindric Worth Rostering for DFS At Martinsville?
Jerami Grant

Won't Play Against Wizards
Pascal Siakam

Iffy for Sunday
Chet Holmgren

Available Against Knicks Sunday
Norman Powell

May Miss Sunday's Game
Jaylen Brown

Questionable Sunday
Kevin Porter Jr.

Unlikely to Return This Season
Denny Hamlin

the Favorite to Win at Martinsville
Ryan Blaney

Should Contend at Martinsville
Tyler Reddick

Should Come Back Down to Earth at Martinsville
Joey Logano

Will Be Strong at Martinsville
Deshaun Watson

in "Pole Position" to be Week 1 Starting QB?
NASCAR

Bubba Wallace Looking to Rebound at Martinsville
Shane Van Gisbergen

Shane van Gisbergen Showing Progress, Qualifies Fifth at Martinsville
Gabriel Vilardi

has a Two-Point Performance
Ivan Demidov

Collects Two More Points on Saturday
Alexandre Sarr

Out Sunday vs. Trail Blazers
Neemias Queta

Questionable for Sunday
Jayson Tatum

Could Rest on Back-to-Back
Derrick White

Could Miss Hornets Game
Immanuel Quickley

Remains Sidelined vs. Magic
Brandon Ingram

Questionable Against Orlando
Luka Dončić

Luka Doncic to Serve One-Game Suspension Monday
Walter Clayton Jr.

is Available for Saturday's Game
Dylan Cease

Fans 12 in Blue Jays Debut on Saturday
Jahmai Mashack

is Returning on Saturday
Guerschon Yabusele

is Absent on Saturday
Malik Monk

Moves into Starting Five on Saturday
Kyler Murray

Dynasty Value Gets New Life With Move to Minnesota
Jonathan Kuminga

to Sit Out on Saturday
Onyeka Okongwu

Won't Play on Saturday
Rachaad White

Is Rachaad White the New RB1 for the Commanders?
Jock Landale

is Cleared for Saturday's Game
Shane Wright

Exits Early Saturday
Connor Zary

Remains Out Saturday Night
Noah Laba

a Game-Time Call Sunday
Jonathan Quick

to Remain Unavailable Sunday
Stefon Diggs

Still a Free Agent With April Approaching
Joel Hanley

to Miss Rest of Season
Alvin Kamara

Workload Expected to Look Drastically Different in 2026
Ethen Frank

Remains Out Saturday
Robert Thomas

Available Saturday
Andrew Vaughn

Needs Hand Surgery, Expected to be Out 4-6 Weeks
Jacob deGrom

"Confident" he Will Make his Next Start
Trey Benson

Facing Uphill Battle for Playing Time in Arizona
Jacory Croskey-Merritt

Can Jacory Croskey-Merritt Emerge as the Clear RB1 in Washington?
Lamar Jackson

Looking for Return to Full Health in 2026
Sean Tucker

Remains Buried on Buccaneers' Running Back Depth Chart
Jake Tonges

Appears Likely to Enter 2026 Atop 49ers' Tight End Depth Chart
NFL

Can Ja'Kobi Lane Carve Out a Fantasy-Relevant Role as a Rookie?
Chig Okonkwo

Instantly Jumping to Fantasy Relevance in Washington?
Aaron Jones Sr.

Set for Familiar Role in 2026?
Brandon Aiyuk

a Buy-Low Candidate in Dynasty Leagues?
Romeo Doubs

the New No. 1 Target in New England?
Daniel Jones

a QB1 if Ready for Season Opener?
Jacob deGrom

Scratched From Saturday's Start Due to Neck Stiffness
Jeferson Quero

Brewers Calling Up Catching Prospect Jeferson Quero
Josh Allen

Still the Top Dog at QB in Fantasy
Jared Goff

Should Have Safe Floor as QB1 Again Under New Offensive Coordinator
Jacoby Brissett

Will Jacoby Brissett be on the Streaming Radar Again in 2026?
NFL

Kaytron Allen Should Attract Plenty of Interest in 2026 NFL Draft
NFL

Makai Lemon a Polarizing Receiver Prospect Heading into This Year's Draft
David Pastrnak

Riding 11-Game Point Streak
John Gibson

Gets Back on Track Friday
J.T. Miller

Bags Three Points Against Blackhawks
Tage Thompson

Picks Up 400th Career Point
Patrick Kane

Collects Two Points in Friday's Win
Deyvison De Los Santos

Marlins Promote Deyvison De Los Santos to Major Leagues
Shea Langeliers

Hits Two Home Runs on Opening Day
Kevin Gausman

Picks Up No-Decision But Strikes Out 11 on Opening Day
Tanner Bibee

Day-to-Day, Could Make his Next Start
Shane Baz

Orioles Agree to Five-Year Extension
Jeremy Peña

Jeremy Pena Making Season Debut on Friday Against Angels
Tiger Woods

Involved In Rollover Car Crash
Tanner Bibee

Shoulder Issue Not Considered Serious
Joe Pyfer

Set For UFC Seattle Main Event
Israel Adesanya

Returns At UFC Seattle
Maycee Barber

Looks To Extend Her Win Streak To Eight
Alexa Grasso

Looks To Get Back In The Win Column
Dominic Canzone

a Top Pickup After Two-Homer Game
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Chase DeLauter

Launches Two Home Runs, Emerges as Top Waiver-Wire Target
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
Tanner Bibee

Leaves Opening Day Start Early With Shoulder Inflammation
Cristopher Sánchez

Cristopher Sanchez Makes a Statement on Opening Day With 10 Strikeouts
Kevin McGonigle

has Four Hits in Impressive MLB Debut
Nico Hoerner

Cubs Agree to Six-Year Deal With Nico Hoerner
Jacob Misiorowski

Shows Off his High-Strikeout Upside in Opening Day Win
Paul Skenes

Greeted Harshly by Mets on Opening Day
Brandon Lowe

Hits Two Home Runs on Opening Day
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Scottie Scheffler

Withdraws From Texas Children's Houston Open
Luke Clanton

Might Have a Problem in Houston
Sam Stevens

Happy to See Houston This Week
Keith Mitchell

Tries to Rebound After The Players Championship
Will Zalatoris

Returning This Week at Houston
Wyndham Clark

Trending in the Wrong Direction Heading to Houston
Shane Lowry

Seeking Better Luck in Houston This Weekend
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF