👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


FanDuel NFL DFS Lineup Picks for Week 10 - Daily Fantasy Football

Dennis Clausen highlights the top FanDuel NFL DFS lineup picks for Week 10 of the 2021 season, and some value sleepers for your daily fantasy football rosters.

What a wild Week 9 it was. With so many players not only failing to meet projections but also falling well below, the scores throughout the DFS community weren't the prettiest by any means. Yet, it was likely a good day for those who turned to James Conner, Jonathan Taylor, Nick Chubb, or Joe Mixon as their preferred options. Additionally, we can't forget about Lamar Jackson or Justin Herbert's contributions, either, while also acknowledging the performance of the returning George Kittle, who had six receptions for 101 yards and a touchdown in his first game since suffering a calf injury back in Week 4. We also saw some wideouts come out of nowhere to make some noise, with Elijah Moore and Olamide Zaccheaus crushing their respective values.

Of course, things have certainly changed since the conclusion of Week 9, with the top story heading toward Sunday being the unfortunate incident involving Dalvin Cook, who is in danger of possibly missing time. Although that may not happen as early as the Vikings meeting against the Los Angeles Chargers, it's certainly a situation fantasy managers want to keep an eye on, mainly if Cook gets suspended. If that's the case, Alexander Mattison will automatically assume the role as the team's top back, and we all know what the 23-year-old is capable of when given a chance.

In this article, I will be providing you with my Week 10 daily fantasy football lineup picks for FanDuel’s “Main Slate.” These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Feel free to give me a follow on Twitter @DennisMClausen.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

FanDuel Quarterbacks - Week 10 DFS Lineup Picks

Josh Allen, QB - vs. NYJ ($8,700)

We shouldn't be ready to give up on Allen, who surprisingly performed terribly during the improbable loss to the Jaguars. After he got off to a slow start against the Dolphins in Week 7, many had assumed that the bye would do him some good. However, that's not how things played out, as the former Wyoming Cowboy had one of the worst performances of his career against Jacksonville.

Nonetheless, Allen can help lessen the sting by turning things around against the Jets. Fortunately, he has a good chance, actually an excellent chance, of doing just that against a New York team that has struggled defensively, allowing 130 points combined against the Patriots, Bengals, and Colts over the last three weeks.

Dak Prescott, QB - vs. ATL ($8,100)

Prescott returned last Sunday against the Broncos after dealing with a calf injury that forced him to miss some time. Despite the possibility of being rusty, the veteran was still expected to have his way with the Denver defense. Yet, that didn't happen, and just like in Josh Allen's case, his output was a colossal disappointment. Still, he's allowed a free pass, primarily since he likely wasn't 100 percent, so we can put that disastrous outing behind him and move on to Atlanta.

Prescott stated that he has been working on his footwork during practice throughout the week, which was an issue against the Broncos. With that, he should regain some confidence, especially regarding planting his foot during throws, something he had a problem doing during the loss. To make things even more enticing, Vegas has the Cowboys as one of the top-scoring teams on the slate, so it's more likely than not he will bounce back against the Falcons.

Also Consider: Patrick Mahomes ($8,400), Justin Herbert ($8,000)

 

FanDuel Running Backs - Week 10 DFS Lineup Picks

James Conner, RB - vs. CAR ($7,000)

Kyler Murray and DeAndre Hopkins didn't suit up for the Week 9 showdown against the 49ers, and it was seemingly a foregone conclusion that the Cardinals would get smoked. Let's face it, Colt McCoy hasn't been the most reliable signal-caller through the years, and while Christian Kirk and Rondale Moore have had their moments of efficiency, not having an MVP candidate or a stud receiver in the lineup isn't ideal.

Yet, Arizona has arguably the best one-two punch out of the backfield in Conner and Chase Edmonds, so naturally, they were expected to serve as a crutch for McCoy when things got rough. Yet, things got even worse for the birds after Edmonds went down with a high-ankle sprain and didn't finish the game as a result. Luckily, Conner, who most believed was well past his prime, turned on the burners and carried the team on his back to a win.

The former Steeler was already playing well leading up to bout versus San Francisco, scoring at least once in five of his eight showings on the year. Yet, he surpassed expectations by finding the end zone three times in total while racking up nearly 100 rushing yards. He also caught all five of his targets for 77 yards. With Edmonds now out for the foreseeable future, Conner should get plenty of opportunities to produce against a shoddy Panthers defense, even if Murray and Hopkins can make it back.

D'Ernest Johnson, RB - @ NE ($5,400)

When we thought we'd seen the last of Johnson, here he is again, ready to occupy space in an abundance of DFS lineups. Yes, we'd love to believe we can get away with other options to go against the crowd. However, when considering his potential points total in relation to his value, we may not have any other choice than to keep him under consideration against New England.

Kareem Hunt remains out with a calf issue, and Nick Chubb has, you guessed it, COVID-19, so Johnson should be in line to handle the bulk of the work in Week 10. The 22-year-old was a menace against Denver during his only start of the season by racking up 146 yards and a touchdown off 22 carries. He also had a pair of receptions for 22 yards. It isn't unreasonable to believe he may see that same workload against the Patriots. Yet, even if he doesn't produce the way he did against the Broncos, the bargain opportunity certainly makes rolling with Johnson worth the risk.

Also Consider: Jonathan Taylor ($9,400), Austin Ekeler ($8,600), Dalvin Cook ($8,500), Darrel Williams ($6,000), Mark Ingram II ($5,500)

 

FanDuel Wide Receivers - Week 10 DFS Lineup Picks

Davante Adams, WR - vs. SEA ($8,700)

Adams wasn't available for Thursday Night Football versus Arizona in Week 8 after he was placed on the reserve/COVID-19 list. Yet, he made his return last Sunday against Kansas City, albeit he didn't have Aaron Rodgers throwing him the ball. With Rodgers out against the Chiefs because of a positive COVID-19 diagnosis, Jordan Love got the first start of his career.

Without a doubt, the absence of the reigning MVP signal-caller didn't do Adams any favors. He would finish with only 42 receiving yards, catching just six of his 14 looks from Love throughout the game. Fortunately, Rodgers is on track to play against the Seahawks. Still, even if Rodgers doesn't, Adams has plenty of room to produce against Seattle.

Tyreek Hill, WR - @ LV ($8,400)

Hill began the year by nearly compiling 200 yards against the Cleveland Browns. However, he hasn't been as consistent as most fantasy managers had expected him to be since then. Sure, he's had some good outings. Yet, he's had some bad ones as well.

Nonetheless, now is a good time for DFS enthusiasts to start believing in the 27-year-old. His rostering cost is super low. Also, Hill has played well versus the Raiders throughout his career by hauling in 43 catches for 635 yards and six total touchdowns. Although historical trends don't necessarily result in similar outcomes, everyone should be willing to take a chance on this one.

Also Consider: Cooper Kupp ($9,500), Justin Jefferson ($7,500), Diontae Johnson ($7,400), Keenan Allen ($7,200)

 

FanDuel Tight Ends - Week 10 DFS Lineup Picks

Darren Waller, TE - vs. KC ($7,000)

Las Vegas has had its share of ups and downs this year. While the team is playing better than most had anticipated, it's even more impressive that the Raiders have a winning record when you consider the organization parted ways with its head coach, Jon Gruden, and leading wideout, Henry Ruggs III.

Without Ruggs, it was expected that others would step up, and that's just what happened against the Giants. However, Waller remained the most involved by providing a source of comfort for Derek Carr. Overall, Waller received 11 looks from Carr, with the 29-year-old bringing in seven catches for a game-high 92 yards. It will be a battle of arguably the best tight ends in the league, as Waller and Travis Kelce will square off in an AFC West showdown. Fortunately for the former Georgia Tech Yellow Jacket, the Chiefs haven't played well on the defensive end all year. It's also expected that Waller will continue to get more than enough attention from Carr not only in Week 10 but for the remainder of the year.

Also Consider: Travis Kelce ($7,500)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Tyjae Spears

has Limited Long-Term Upside in Dynasty Formats
Jaylen Wright

a Buy-Low Candidate as a Handcuff?
Ollie Gordon II

Dynasty Value Takes a Hit After Teammate's Extension
Ryan Johnson

Takes Over as Canucks GM, Sedins Promoted to Co-Presidents
Drew Helleson

Won't Play Thursday
Radko Gudas

Unlikely to Play Thursday
Jeremy Lauzon

Remains Out Thursday
Mark Stone

Misses Third Consecutive Game
EDM

Kris Knoblauch Fired as Oilers Head Coach
Micah Parsons

Expected to Miss the Early Part of the Season
Colby Parkinson

a Clear Dynasty Sell-High Candidate Entering 2026
Omarion Hampton

Poised for Year 2 Breakout in Los Angeles
Blake Corum

Dynasty Stock Rising After Encouraging 2025 Campaign
Jaxson Dart

Does Jaxson Dart Carry High-End Dynasty QB1 Upside?
David Montgomery

Dynasty Stock Rising Following Move to Houston
Chris Godwin Jr.

Can Chris Godwin Jr. Re-Establish His Dynasty Value in 2026?
Malik Willis

Not Set Up for Immediate Success in Miami
Terrance Ferguson

has Promising Receiving Skills in Crowded TE Room in L.A.
Brenton Strange

Is Brenton Strange a Top-15 Dynasty Tight End?
T.J. Watt

Steelers Ready to Move on From T.J. Watt?
Jacory Croskey-Merritt

Must Make Gains as Pass-Catcher to Take the Next Step
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
Kaytron Allen

Could Kaytron Allen Take on a Big Role Right Away?
Demond Claiborne

Has Long-Term Appeal in Minnesota
Byron Buxton

Scratched on Thursday With Hip Soreness
Cal Raleigh

Heading to Injured List With Oblique Strain
Adam Randall

to Contribute as a Pass-Catcher Right Away?
Francisco Alvarez

has Knee Surgery, Expected to Miss Eight Weeks
Nicholas Singleton

Could Contribute Right Away
Bryce Lance

a Perfect Fit in New Orleans?
Mike Washington Jr.

Can Mike Washington Jr. Force a Backfield Split in Vegas?
Paul Reed

Makes Big Impact Off the Bench Wednesday
Daniss Jenkins

Contributes 19 Points As Starter
Cade Cunningham

Tallies 39 Points in Losing Effort
Max Strus

Notches 20 Points With Six Triples
Evan Mobley

Close to Triple-Double Wednesday
Jarrett Allen

Records Double-Double in Game 5 Win
James Harden

Leads the Way for Cavaliers in Game 5 Victory
Quinn Hughes

Finishes Postseason With 15 Points
Matt Boldy

Posts Two Assists in Season-Ending Loss
Scott Wedgewood

Perfect in Relief Effort
Martin Necas

Records Another Multi-Point Game
Brett Kulak

Sends Avalanche Into Conference Finals
Brayden McNabb

Suspended for One Game
Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
CFB

Isaac Brown Has All-American Upside in 2026
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF