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FanDuel MLB DFS Lineup Picks (6/4/21): Daily Fantasy Baseball Advice

Christian Yelich - Fantasy Baseball Rankings, MLB DFS Picks, Betting Picks

Juan Carlos Blanco highlights the top FanDuel MLB DFS lineup picks for 6/4/21, and a couple of sleepers to consider while building daily rosters.

Friday night’s main slate features a full 15-game smorgasbord, giving us no shortage of options to choose from when it comes to hitters. There are also some impressive pitchers taking the hill, and we’ll focus on a couple that are at differing points on the salary scale.

We’re fortunate that there are some attractive ballparks serving as host venues as well -- Camden Yards, Coors Field, Kauffmann Stadium and American Family Field will feature games where the runs could certainly pile up.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel main slate on 6/4/2021. Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also read more DFS advice and lineup picks for sites like DraftKings, and other sports.

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FanDuel DFS Pitchers

Cash Game/GPP Anchor Play:

Zack Wheeler – vs. WSH ($11,500)

Wheeler is the highest-salaried player on the slate and has an elite arm in Max Scherzer opposing him, but I still see him as worth the investment Friday. The right-hander has a 1.88 ERA and 0.67 WHIP, along with a 3-0 mark, over 43 home frames. Wheeler’s 11.0 K/9 and 0.7 HR/9 are also elite, and he’s already posted 37 FD points against the Nationals in a road start this season. Washington comes into Friday’s matchup with a 28.6 percent strikeout rate, .229 average and pedestrian .308 wOBA against righties on the road over the last two weeks. Wheeler has also flashed a ceiling worthy of his salary this season, as he’s posted over 50 FD points in five of his last seven starts.

Potential Alternate Play

Freddy Peralta – vs. ARI ($8,700)   

Peralta sports a very reasonable salary for a pitcher that’s averaged 35.3 FD points this season and that’s posted 49 FD points or more in three of his last four starts. Peralta has been absolutely stellar at home as well, pitching to a 3-0 record, 1.41 ERA, 0.69 WHIP, .102 BAA and 12.9 K/9 across 32 innings. Friday, he gets a crack at a D-Backs team that’s averaging just 3.8 runs per away game and that’s posted a .198 average, .259 wOBA, .096 ISO and -14.3 wRAA against right-handed pitching at home over the last month.

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FanDuel DFS Infielders

Jared Walsh, 1B, vs. SEA ($3,600)

Walsh has been outstanding all season, slashing .300/.362/.558 with a .390 wOBA,.258 ISO and 27.9 percent HR/FB rate. He’s set for a premium matchup against spot starter Robert Dugger, who was just recalled from Triple-A Tacoma and who’s pitched to a 6.23 ERA and 1.44 WHIP across 17.1 big-league innings this season. Dugger has particularly struggled against left-handed hitters, who’ve tagged him for a .296 average, .345 wOBA and 5.08 xFIP. What’s more, Dugger has shown some serious flyball tendencies versus lefty bats, allowing a 52.4 percent FB rate to that handedness. Given Walsh’s success knocking the ball out of the park when putting it in the air against righties, that makes this an especially promising matchup for the surging slugger. When Dugger exits, Walsh continues to be in a good position, as Mariners relievers have allowed a 7.43 ERA, .292 average and .374 wOBA to lefty bats over the last month.

Tommy Edman – 2B, vs. CIN ($2,700)

Edman entered Thursday having slashed .321/.371/.536 with six doubles, two home runs, nine RBI, four walks, three stolen bases and 10 runs across his previous 14 games. The switch hitter draws a favorable matchup Friday against a talented but undeniably struggling pitcher in Luis Castillo, who he’s already tagged for a .375 average and .375 on-base percentage with zero strikeouts in 16 career plate appearances. Edman has had his greatest success against lefties, but he does own a .287 average versus righties at home, along with a 23.4 percent line-drive rate in that split. Meanwhile, Castillo has had plenty of trouble versus left-handed hitters, surrendering a .325 average, .907 OPS and .389 wOBA in that split this season.

Josh Fuentes– 3B, vs. OAK ($3,000)

Fuentes offers some cost-effective exposure to the Rockies end of Friday’s Coors Field clash, and he checks in with a .271 average, .220 ISO and .758 OPS against right-handed pitching at home. Fuentes has a solid 38.6 percent hard-contact rate in that split as well, while A’s starter Frankie Montas has allowed a .366 wOBA, 2.2 HR/9 and .850 OPS to right-handed hitters, along with a 5.49 xFIP when facing righty bats on the road. The Coors setting naturally only makes the entire scenario more appealing and helps to nullify the fact Montas has had the majority of his issues at home. It also helps that Fuentes has enjoyed plenty of success against Montas’ trademark sinker, posting a .389 wOBA and striking out just 7.7 percent against that offering this season.

Marcus Semien – SS, vs. HOU ($3,700)

Semien entered Thursday on a torrid pace at the plate, as he’d slashed .400/.480/.769 with 13 extra-base hits and 12 RBI over his last 16 games. The veteran infielder no longer has TD Ballpark in Dunedin to call home now that Toronto is closer to home in Buffalo’s Sahlen Field, but the latter is also a very hitter-friendly venue. Friday, Semien gets a tough matchup on paper against Zack Greinke, but it’s one he’s often mastered in the past – he owns a 389 average with only one strikeout across 20 career plate appearances versus the accomplished right-hander. Semien checks in with a .393 wOBA overall, and a .318 average, .992 OPS and .422 wOBA versus right-handed pitching specifically. Greinke has a solid 5-2 record and 3.67 ERA, but he has a 6.96 K/9 that’s his lowest since 2005 while also allowing a .279 average, 25.4 percent line-drive rate and .333 wOBA to right-handed hitters.

 

FanDuel DFS Outfielders

Christian Yelich– vs. ARI ($3,600)

Yelich makes for a very high-upside left-handed bat to roster against D-Backs starter Matt Peacock, who’s allowed a .283 average, .900 OPS and .368 wOBA to lefty hitters in a 48-batter sample thus far. Peacock has been extremely effective in a very small road sample this season, but Yelich checks in with a .334 wOBA against right-handed pitching and is still in the process of finding his groove after playing in only 23 games to date. Yelich will also draw a premium matchup once Peacock exits, as D-Backs relievers have allowed a .307 average, .365 wOBA and 1.7 HR/9 to left-handed hitters over the last month.

Alex Kirilloff- at KC ($2,700)

Kirilloff is holding his own against big-league arms thus far, posting a .242 average and .440 slugging percentage across 97 plate appearances going into Thursday. The rookie has an elite .398 xwOBA and .627 xSLG as well, and he’s hit three of his four homers thus far off righties. Meanwhile, Royals starter Brad Keller has struggled against both handedness of hitter, and he’s surrendering a .362 average, .438 wOBA and massive 30.8 percent line-drive rate to lefty bats at home specifically. Royals relievers have had their share of struggles against left-handed hitters at home in the last month as well, allowing a 5.91 ERA, .824 OPS and .351 wOBA across a 97-batter sample.

Austin Meadows– at TEX ($4,300)

Meadows checked into Thursday with four homers in his previous six games, a stretch during which he’s hit .450 with 10 RBI across 26 plate appearances. The lefty-hitting slugger gets an opposite-handed matchup versus a veteran in Kyle Gibson who’s slated to come off the injured list due to a groin issue for this start. Gibson has been impressive against both handedness of hitter thus far, but Meadows has been lethal on the road versus righties to the tune of a .277 average, .317 ISO and .398 wOBA, along with a 154 wRC+. Texas relievers could be excellent targets for Meadows as well, as they’ve allowed a .292 average and .343 wOBA to lefty hitters at home in the last month.



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REAL-TIME FANTASY NEWS

Darius Garland

Exits Early Wednesday With Foot Injury
Jalen Suggs

to Miss Sixth Straight Game Thursday
Wendell Carter Jr.

Cleared to Play in Berlin
Myles Turner

Available Thursday
Deni Avdija

Likely to Remain Out Thursday
Jaylen Brown

Ready to Face Heat Thursday
Bruce Brown

Spencer Jones, Bruce Brown Available Wednesday
Aaron Gordon

Cleared for Wednesday Night
Jamal Murray

Active Wednesday Night
Cade Cunningham

Ready to End Two-Game Absence
Devin Booker

Questionable for Thursday Night
Giannis Antetokounmpo

Probable to Face Spurs
Brandon Williams

Available Wednesday
Max Christie

Out Wednesday
P.J. Washington

Returns to Action Wednesday
Scotty Pippen Jr.

Season Debut Delayed for at Least Four More Weeks
Brandon Clarke

to Miss 4-6 More Weeks
Josh Giddey

Starting Ramp-Up Period, Could Return Soon
Ja Morant

Unavailable Thursday
Julian Phillips

Out Wednesday
Coby White

to Be Limited to 28-30 Minutes Wednesday
Mackenzie Blackwood

Activated From Injured Reserve
Ben Griffin

Looks To Stay Hot In 2026
Tom Wilson

Cleared for Contact, Could Return Thursday
Neal Pionk

Lands on Injured Reserve, Out Week-to-Week
Jamie Drysdale

Activated From Injured Reserve
Corey Perry

Unavailable Wednesday
Teuvo Teravainen

to Miss at Least One Game
Connor Bedard

Returns to Practice
Alexandre Texier

Canadiens Sign Alexandre Texier to Two-Year Extension
New York Giants

Giants Making "Massive Push" to Hire John Harbaugh on Wednesday
Ranger Suárez

Ranger Suarez Agrees to Five-Year Deal With Red Sox
CFB

Dante Moore Not Entering 2026 NFL Draft, Will Return to Oregon
NFL

Mike Tomlin Doesn't Plan to Coach in 2026
Travis Hunter

Expected to Play More Defense in 2026
CFB

FBS Coaches Unanimously Vote to Expand Redshirt Eligibility to Nine Games
CFB

Ohio State Transfer Mylan Graham Signs with Notre Dame
CFB

Caden Durham Withdraws from Transfer Portal, Will Stay at LSU
Leon Draisaitl

Has Three Points in Tuesday's Loss
Joel Hofer

Controls Hurricanes Tuesday
Jordan Spieth

Perhaps the Most Intriguing Player at Sony Open
Jeremy Swayman

Posts First Shutout of the Season
Zach Werenski

Totals Three Points in Tuesday's Win
Chandler Stephenson

Available Wednesday
Aaron Rai

Looking For Putting Confidence at Waialae Country Club
Jonathan Marchessault

Moved to Injured Reserve
Brayden Point

Labeled Week-to-Week
Collin Morikawa

Isn't The Safe Play He Used to Be Ahead of Sony Open
Kurt Kitayama

Needs His Putting to Turn Around For Success at Year's First Event
Ryan Weathers

Yankees Add Rotation Depth, Acquire Ryan Weathers in Four-Player Deal
Robert Thomas

Out Tuesday
Jake Walman

Available Against Predators
Troy Terry

a Game-Time Decision Tuesday
Justin Sourdif

Won't Play Tuesday
Jakob Chychrun

a Game-Time Call Tuesday
Morgan Geekie

Available Tuesday
Los Angeles Chargers

Chargers Fire Offensive Coordinator Greg Roman
Pittsburgh Steelers

Mike Tomlin Stepping Down as Steelers Head Coach
CFB

Georgia Tech the Favorite to Land Justice Haynes?
Nolan Arenado

Cardinals Trade Nolan Arenado to Diamondbacks
Tom Kim

Desperately Needs a Solid Week at Sony Open
Billy Horschel

Hoping For a Fast Start to New Season at Sony Open
Corey Conners

Looks to Have a Return to Form in 2026
PGA

Chris Gotterup a Decent Play at Sony Open
Gary Woodland

Could Prosper at the Sony Open
Keith Mitchell

Unlikely to Contend at Sony Open
Robert MacIntyre

Looking for a Good Performance at the Sony Open
Michael Kim

Hopes to Start Sony Open Better This Week
Tom Hoge

Tries to Erase Poor 2025 Second Half in Hawaii
Brian Harman

Seeks Fresh Start in Hawaii
Eric Cole

Looks to Last Year for Success at Sony Open
Daniel Berger

Starts Off 2026 at Sony Open
Nico Collins

Suffers Concussion Against Steelers
Nico Collins

Carted to Locker Room for Concussion Evaluation
Kyle Tucker

Mets Meet With Kyle Tucker
Dalton Kincaid

"Should be Fine" for Divisional Round
Brooks Koepka

Officially Returning To PGA Tour
Tucker Kraft

Hopes to be Ready for Week 1 of Next Season
CFB

Georgia Lands Kentucky Transfer Dante Dowdell
Matthew Stafford

has "Little Sprain," Should be "Good to Go"
CFB

Sam Leavitt Expected to Sign with LSU
Green Bay Packers

Packers Expected to Work Out New Deal With Matt LaFleur in the "Coming Days"
CFB

Dylan Raiola Commits to Oregon
CFB

Isaiah Horton Landing with Texas A&M
George Kittle

Suffers Torn Achilles on Sunday
Omarion Hampton

Active for Wild-Card Round Against Patriots
George Kittle

Ruled Out After Non-Contact Achilles Injury
Las Vegas Raiders

Raiders Request Interview With Ejiro Evero
Los Angeles Rams

Mike LaFleur to Interview With Raiders and Cardinals
Aaron Rodgers

Steelers Open to Re-Signing Aaron Rodgers?
Matthew Stafford

X-Rays Come Back Negative
MacKenzie Gore

Yankees Pursuing Trade for MacKenzie Gore
Alex Bregman

Cubs Sign Alex Bregman to Five-Year, $175 Millon Contract
Freddie Freeman

Withdraws from World Baseball Classic
Max Kepler

Receives 80-Game PED Suspension
CFB

Cam Coleman Visiting Alabama on Friday
Omarion Hampton

Expects to Play Sunday Night
CFB

Eric Singleton Jr. Enters Transfer Portal, Trending to Land at Florida
CFB

NCAA Denies Trinidad Chambliss a Sixth Year of Eligibility
Omarion Hampton

Questionable for Wild-Card Weekend
Kyle Tucker

Mets Remain in Mix for Kyle Tucker
Ketel Marte

Will Remain With Diamondbacks
Rashee Rice

to be Reviewed Under League's Conduct Policy

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