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FanDuel MLB DFS Lineup Picks (6/4/21): Daily Fantasy Baseball Advice

Christian Yelich - Fantasy Baseball Rankings, MLB DFS Picks, Betting Picks

Juan Carlos Blanco highlights the top FanDuel MLB DFS lineup picks for 6/4/21, and a couple of sleepers to consider while building daily rosters.

Friday night’s main slate features a full 15-game smorgasbord, giving us no shortage of options to choose from when it comes to hitters. There are also some impressive pitchers taking the hill, and we’ll focus on a couple that are at differing points on the salary scale.

We’re fortunate that there are some attractive ballparks serving as host venues as well -- Camden Yards, Coors Field, Kauffmann Stadium and American Family Field will feature games where the runs could certainly pile up.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel main slate on 6/4/2021. Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also read more DFS advice and lineup picks for sites like DraftKings, and other sports.

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FanDuel DFS Pitchers

Cash Game/GPP Anchor Play:

Zack Wheeler – vs. WSH ($11,500)

Wheeler is the highest-salaried player on the slate and has an elite arm in Max Scherzer opposing him, but I still see him as worth the investment Friday. The right-hander has a 1.88 ERA and 0.67 WHIP, along with a 3-0 mark, over 43 home frames. Wheeler’s 11.0 K/9 and 0.7 HR/9 are also elite, and he’s already posted 37 FD points against the Nationals in a road start this season. Washington comes into Friday’s matchup with a 28.6 percent strikeout rate, .229 average and pedestrian .308 wOBA against righties on the road over the last two weeks. Wheeler has also flashed a ceiling worthy of his salary this season, as he’s posted over 50 FD points in five of his last seven starts.

Potential Alternate Play

Freddy Peralta – vs. ARI ($8,700)   

Peralta sports a very reasonable salary for a pitcher that’s averaged 35.3 FD points this season and that’s posted 49 FD points or more in three of his last four starts. Peralta has been absolutely stellar at home as well, pitching to a 3-0 record, 1.41 ERA, 0.69 WHIP, .102 BAA and 12.9 K/9 across 32 innings. Friday, he gets a crack at a D-Backs team that’s averaging just 3.8 runs per away game and that’s posted a .198 average, .259 wOBA, .096 ISO and -14.3 wRAA against right-handed pitching at home over the last month.

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FanDuel DFS Infielders

Jared Walsh, 1B, vs. SEA ($3,600)

Walsh has been outstanding all season, slashing .300/.362/.558 with a .390 wOBA,.258 ISO and 27.9 percent HR/FB rate. He’s set for a premium matchup against spot starter Robert Dugger, who was just recalled from Triple-A Tacoma and who’s pitched to a 6.23 ERA and 1.44 WHIP across 17.1 big-league innings this season. Dugger has particularly struggled against left-handed hitters, who’ve tagged him for a .296 average, .345 wOBA and 5.08 xFIP. What’s more, Dugger has shown some serious flyball tendencies versus lefty bats, allowing a 52.4 percent FB rate to that handedness. Given Walsh’s success knocking the ball out of the park when putting it in the air against righties, that makes this an especially promising matchup for the surging slugger. When Dugger exits, Walsh continues to be in a good position, as Mariners relievers have allowed a 7.43 ERA, .292 average and .374 wOBA to lefty bats over the last month.

Tommy Edman – 2B, vs. CIN ($2,700)

Edman entered Thursday having slashed .321/.371/.536 with six doubles, two home runs, nine RBI, four walks, three stolen bases and 10 runs across his previous 14 games. The switch hitter draws a favorable matchup Friday against a talented but undeniably struggling pitcher in Luis Castillo, who he’s already tagged for a .375 average and .375 on-base percentage with zero strikeouts in 16 career plate appearances. Edman has had his greatest success against lefties, but he does own a .287 average versus righties at home, along with a 23.4 percent line-drive rate in that split. Meanwhile, Castillo has had plenty of trouble versus left-handed hitters, surrendering a .325 average, .907 OPS and .389 wOBA in that split this season.

Josh Fuentes– 3B, vs. OAK ($3,000)

Fuentes offers some cost-effective exposure to the Rockies end of Friday’s Coors Field clash, and he checks in with a .271 average, .220 ISO and .758 OPS against right-handed pitching at home. Fuentes has a solid 38.6 percent hard-contact rate in that split as well, while A’s starter Frankie Montas has allowed a .366 wOBA, 2.2 HR/9 and .850 OPS to right-handed hitters, along with a 5.49 xFIP when facing righty bats on the road. The Coors setting naturally only makes the entire scenario more appealing and helps to nullify the fact Montas has had the majority of his issues at home. It also helps that Fuentes has enjoyed plenty of success against Montas’ trademark sinker, posting a .389 wOBA and striking out just 7.7 percent against that offering this season.

Marcus Semien – SS, vs. HOU ($3,700)

Semien entered Thursday on a torrid pace at the plate, as he’d slashed .400/.480/.769 with 13 extra-base hits and 12 RBI over his last 16 games. The veteran infielder no longer has TD Ballpark in Dunedin to call home now that Toronto is closer to home in Buffalo’s Sahlen Field, but the latter is also a very hitter-friendly venue. Friday, Semien gets a tough matchup on paper against Zack Greinke, but it’s one he’s often mastered in the past – he owns a 389 average with only one strikeout across 20 career plate appearances versus the accomplished right-hander. Semien checks in with a .393 wOBA overall, and a .318 average, .992 OPS and .422 wOBA versus right-handed pitching specifically. Greinke has a solid 5-2 record and 3.67 ERA, but he has a 6.96 K/9 that’s his lowest since 2005 while also allowing a .279 average, 25.4 percent line-drive rate and .333 wOBA to right-handed hitters.

 

FanDuel DFS Outfielders

Christian Yelich– vs. ARI ($3,600)

Yelich makes for a very high-upside left-handed bat to roster against D-Backs starter Matt Peacock, who’s allowed a .283 average, .900 OPS and .368 wOBA to lefty hitters in a 48-batter sample thus far. Peacock has been extremely effective in a very small road sample this season, but Yelich checks in with a .334 wOBA against right-handed pitching and is still in the process of finding his groove after playing in only 23 games to date. Yelich will also draw a premium matchup once Peacock exits, as D-Backs relievers have allowed a .307 average, .365 wOBA and 1.7 HR/9 to left-handed hitters over the last month.

Alex Kirilloff- at KC ($2,700)

Kirilloff is holding his own against big-league arms thus far, posting a .242 average and .440 slugging percentage across 97 plate appearances going into Thursday. The rookie has an elite .398 xwOBA and .627 xSLG as well, and he’s hit three of his four homers thus far off righties. Meanwhile, Royals starter Brad Keller has struggled against both handedness of hitter, and he’s surrendering a .362 average, .438 wOBA and massive 30.8 percent line-drive rate to lefty bats at home specifically. Royals relievers have had their share of struggles against left-handed hitters at home in the last month as well, allowing a 5.91 ERA, .824 OPS and .351 wOBA across a 97-batter sample.

Austin Meadows– at TEX ($4,300)

Meadows checked into Thursday with four homers in his previous six games, a stretch during which he’s hit .450 with 10 RBI across 26 plate appearances. The lefty-hitting slugger gets an opposite-handed matchup versus a veteran in Kyle Gibson who’s slated to come off the injured list due to a groin issue for this start. Gibson has been impressive against both handedness of hitter thus far, but Meadows has been lethal on the road versus righties to the tune of a .277 average, .317 ISO and .398 wOBA, along with a 154 wRC+. Texas relievers could be excellent targets for Meadows as well, as they’ve allowed a .292 average and .343 wOBA to lefty hitters at home in the last month.



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REAL-TIME FANTASY NEWS

Jordan Walsh

Questionable Monday Due to Illness
Ivica Zubac

to Miss Three Weeks
Kevin Love

Resting Against Nuggets
Brandon Clarke

Won't Play On Monday
CFB

Bobby Petrino Joining Bill Belichick as North Carolina's Offensive Coordinator
Peyton Watson

Could Remain on Shelf Monday
Herbert Jones

Listed as Questionable Monday
Klay Thompson

Uncertain to Play Monday
T.J. McConnell

Considered Questionable Monday
Collin Sexton

Likely to Remain Out Monday
Jerami Grant

Tagged as Questionable for Monday
Lauri Markkanen

in Danger of Missing Third Consecutive Game
Cooper Flagg

Questionable for Monday's Action
Chet Holmgren

Iffy for Monday
Ja Morant

Remains Out Monday
TreVeyon Henderson

Exits Week 16 Victory with Head Injury
Jaylen Brown

Could Miss Another Game Monday
Mikhail Sergachev

Sets Up Two Goals
Fabian Zetterlund

Extends Scoring Streak With Three-Point Effort
Jalen Suggs

Unlikely to Play vs Warriors
Jalen Duren

Probable for Monday vs Portland
Cale Makar

Has Three-Point Performance Against Wild
Isaiah Hartenstein

Sidelined to Open Back-to-Back
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Notches Three Points Sunday
Ryan Kalkbrenner

Uncertain for Monday With Elbow Injury
Connor McDavid

Continues Scoring Tear Against Vegas
LaMelo Ball

On Track to Suit Up Against Cleveland
Sidney Crosby

Becomes Pittsburgh's All-Time Leading Scorer
Tristan Jarry

to Miss Couple of Weeks
Lamar Jackson

Questionable to Return in Week 16 with Back Injury
Donovan Mitchell

Likely to Return on Monday Night
Willson Contreras

Shipped to the Red Sox
Patrick Kane

to Miss Fifth Consecutive Game
Tyson Kozak

Misses Second Consecutive Game
Jack Roslovic

Ready to Return Sunday
NJ

Arseni Gritsyuk Back in Devils Lineup Sunday
Timo Meier

Available Sunday
Jack Hughes

Returns From 18-Game Absence Sunday
J.T. Miller

Out Week-to-Week
Quinshon Judkins

Done for the Season with Broken Leg
Gardner Minshew

Likely Tore His ACL on Sunday
Nick Chubb

Officially Active Against Raiders in Week 16
Gardner Minshew

Won't Return in Week 16
Woody Marks

Officially Inactive for Week 16
Quinshon Judkins

Carted Off in Week 16, Ruled Out with Apparent Leg Injury
Tua Tagovailoa

Dolphins Hope to Trade Tua Tagovailoa in the Offseason
Woody Marks

Not Expected to Play in Week 16
Washington Commanders

Commanders to Retain Dan Quinn, Fire Joe Whitt?
New York Giants

Marcus Freeman is a Top Candidate in Giants' Head Coaching Search
Cincinnati Bengals

Zac Taylor Expected to Return as Bengals' Head Coach in 2026
Las Vegas Raiders

Pete Carroll's Future with Las Vegas Raiders in Doubt
Tee Higgins

Active for Week 16 Against Dolphins
Tage Thompson

Scores in Sixth Consecutive Game
Jacob Fowler

Posts First Career Shutout
Jonatan Berggren

Totals Three Points Saturday
Jake Evans

to Sit Out Sunday's Game
Zach Werenski

Injured in Saturday's Loss
Frank Nazar

Expected to Miss Four Weeks
Woody Marks

Plans to Play Against Raiders in Week 16
Tee Higgins

Likely to Play at Miami on Sunday
Drake London

Expected to Return in Week 16
Marvin Harrison Jr.

Expected to Play, Will Ease Back In
Romeo Doubs

Questionable to Return Against Bears in Week 16
Jordan Love

Ruled Out with Concussion, Replaced by Malik Willis
Mike Matheson

Returns Against Former Team Saturday
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
Shane Baz

Orioles Acquire Shane Baz From the Rays
CFB

Darian Mensah Returning to Duke Next Season
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Josh Hoover Linked to Indiana in Transfer Portal
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Arch Manning Agrees to Reduced Compensation for 2026 Season
Michael King

Padres Bring Michael King Back on Three-Year Deal
Logan Webb

Will Pitch for Team USA in World Baseball Classic
Tarik Skubal

Joins Team USA for World Baseball Classic
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Will Muschamp Becoming Next Texas Defensive Coordinator
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Beau Pribula Set to Enter Transfer Portal
Bo Bichette

Willing to Make the Move to Second Base
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Jeremiyah Love Officially Heading to NFL Draft
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Jake Merklinger Leaving Tennessee for Transfer Portal
Mike Trout

Angels Open to Mike Trout Playing Center Field in 2026
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Kansas State's Jayce Brown Intends to Transfer
CFB

Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
Justin Crawford

Phillies Planning to Start Justin Crawford in Center Field
CFB

Jayden Maiava Signs New Deal to Return to USC
CFB

Aidan Mizell Won't Return to Florida, Entering Transfer Portal

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