X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

DraftKings Daily Fantasy Basketball Picks (4/22/21): NBA DFS Lineups

The top daily fantasy basketball lineup picks for DraftKings on April 22, 2021. Euan Leith provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

Happy Thursday, RotoBallers! As is usually the case for the fourth day of the week, the association provides a small(ish) six-game slate to start the weekend early. Six teams will be playing the second half of a back-to-back set tonight. Phoenix, Philadelphia, Detroit, Dallas, Chicago, and San Antonio will play their second game in as many nights. This could bring about some strange lineups and cautious starting fives from any of those six squads.

My favorite game is the Philadelphia-Milwaukee contest. The 227.5 points for the over/under is the largest on the slate. Meanwhile, the Bucks are the fastest-paced team among the 12 units playing on Thursday. The rest of the slate is considerably uglier than the 76ers-Bucks matchup. I will be keeping an eye on the lineups out of Boston, however. Several stars are dealing with illnesses and nagging injuries, and their ailments will open up plenty of shots for a lot of underpriced Celtics.

This article will provide you with my daily fantasy basketball lineup picks for DraftKings on 4/22/21. You can also check out today's FanDuel lineup picks. With COVID-19 a significant factor, remember to monitor injury news as the slate can completely change before lineups lock.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 6 free months of RotoBaller's "Big-4" Premium Pass (NBA, NFL, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

DraftKings DFS Guards

Terry Rozier - PG/SG, CHA at CHI ($8,400)

Terry was too scary for me to play on Tuesday's slate, and he made me look dumb. I won't make that mistake tonight as I build my lineups around the 27-year old. Rozier is playing some of the best basketball of his career with LaMelo Ball (wrist) and Gordon Hayward (foot) on the sidelines for the Hornets. Over his last four games, the 2015 first-round pick is averaging 26 points, nine assists, seven rebounds, 4.2 triples, and 1.7 steals per contest. Rozier has gone over 20 points, eight assists, six rebounds, and two three-pointers in all four of those games. It's not up-and-down production, and he's consistently bringing his A-game. This run of form will continue tonight against a Bulls unit allowing the sixth-most DraftKings fantasy points to point guards over their last 15 games.

Marcus Smart - PG/SG, BOS vs. PHO ($6,600)

Reports are coming out of Boston that Jaylen Brown (shoulder), Jayson Tatum (ankle), and Evan Fournier (medical protocols) will all miss this game against the Suns. That leaves an enormous gap in the Celtics offense with 48.6 shots per game sitting on the trainer's table. Kemba Walker ($7,400) is another option in the Boston backcourt for this game, but I'm snagging the $800 in savings and rolling with Smart. He's topped 40 points in three of his last six appearances, and he's never been reluctant to take more shots when given a chance. Smart's season-high is 25 points, and he will have the opportunity to top that against the Suns on Thursday.

Tyrese Maxey - PG/SG, PHI at MIL ($3,100)

Maxey should only be a consideration if Ben Simmons (illness) is unable to play. Simmons did miss the first half of this back-to-back set and is considered questionable for this Eastern Conference showdown. Maxey came off the bench last night and recorded 14 points, three rebounds, three assists, two steals, and a block in 31 minutes against the Suns. We all witnessed his upside in January when the 76ers gave him extended playing time. If he gets the opportunity tonight, he should be one of the first players in your DFS lineup.

 

Want more NBA DFS tools and content? Our NBA Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our NBA analysts. Check out this recent big win from RotoBaller premium member Bsuperak on FanDuel - join in on the winning!

 

DraftKings DFS Forwards

Brandon Ingram - SF/PF, NO at ORL ($8,700)

I prefer Ingram to be a little cheaper than the $8,700 he's sitting at for tonight's slate, but the 23-year old is producing all over the box score in his last handful of games. In the previous five matchups, Ingram is averaging 28.4 points, 5.6 assists, 4.8 rebounds, 1.2 steals, and 2.2 three-pointers. His most explosive fantasy evenings come when he is active on the defensive end. In the last two games where the All-Star reached a combined three blocks plus steals, he is averaging 57.9 FPPG. The Magic enters tonight's game as the third-worst defense versus small forwards over their last 15 games. Ingram has a good matchup and should have a great shot at returning six or seven times his salary if he can bring it defensively.

Patrick Williams - SF/PF, CHI vs. CHA ($4,300)

The Bulls are in a scrap for the play-in games and will need all their guys to step up down the final 15 games. They have another big matchup against the Charlotte Hornets tonight, and it will be a good spot for Patrick Williams. The fourth pick in the 2020 NBA Draft still has some work to do on the offensive side of the ball, but he can contribute in other ways, and it's turning him into a viable DFS option. In four of his last five games, the rookie has scored at least 23 DK fantasy points and returned five times his value. Charlotte is a bottom-third defense against forwards over the last two weeks and will give Williams the chance to continue his decent form. Over the five-game stretch I just mentioned, the 19-year old is averaging 8.4 points, 5.8 rebounds, 2.4 assists, 1.4 steals, and 0.6 blocks while shooting 60.7 percent from the field and 57.1 percent behind the three-point line.

 

DraftKings DFS Centers

Isaiah Stewart - C, DET at SA ($5,800)

Stewart is showing the NBA fans and DFS players what he can do on the court. The 19-year old is producing some phenomenal stat lines and, as a result, excellent DFS results. Mason Plumlee started last night versus Dallas and severely capped his teammate's upside. However, with the Pistons playing the second half of a back-to-back, they may rest their veteran and let the rookie get another long run. In the last three games where Stewart has logged at least 24 minutes, the New York native is averaging 17.3 points, 16.3 rebounds, 2.3 blocks, and 47.4 DraftKings fantasy points. Make sure to check the Piston's starting lineup before the games begin, but if Stewart gets the starting nod, he should be an all-systems-go kind of play.

 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy basketball mobile app for iPhone and Android with 24x7 player news, injury alerts, lineup notifications & DFS articles. All free!

NBA DFS News and Injury Alerts

More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Robert Williams III

Sidelined on Monday
Vít Krejčí

Vit Krejci Unavailable Against Nets
NFL

Ty Simpson Expected to be a First-Round Pick
Jerami Grant

Ruled Out on Monday
Jake Bobo

Seahawks Match Offer Sheet for Jake Bobo
Tommy DeVito

Becomes QB2 in New England
Quentin Johnston

Chargers Unlikely to Trade Quentin Johnston?
Nick Pivetta

to Start on Opening Day for Padres
Brandon Woodruff

Makes Brewers Opening Day Rotation
Zack Wheeler

to Start Rehab Assignment on Saturday
Carson Benge

Makes Mets Opening Day Roster
D'Andre Swift

Facing Playing-Time Questions Heading into 2026
Travis Kelce

Officially Signs New Contract With the Chiefs
NFL

Can Denzel Boston Overcome Speed and Athleticism Concerns at the NFL Level?
NFL

Jadarian Price's Dynasty Stock is Rising as the 2026 Draft Approaches
NFL

Can Chris Bell Make an Immediate Impact in the NFL?
Seiya Suzuki

to Start the Season on the Injured List
Travis Homer

Signs With Steelers as RB Depth
Lerone Murphy

Suffers His First Loss
Dennis Santana

Won't be Pirates' Primary Closer
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
DeVonta Smith

Wide Range of Possible Outcomes for DeVonta Smith in 2026
Woody Marks

to Serve as Backup in Sophomore Season?
Puka Nacua

Extension for Puka Nacua isn't Expected Soon
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Joshua Dobbs

Patriots Planning to Release Joshua Dobbs
Spencer Strider

to Start the Season on Injured List
Iwo Baraniewski

Delivers 28-Second TKO
Lawson Crouse

Picks Up Three Points in Overtime Win
Jahmyr Gibbs

in Line for a Career Workload
Filip Forsberg

Takes Predators Past Blackhawks
Jaxon Smith-Njigba

Becomes Highest-Paid Wide Receiver in NFL History
Alex Ovechkin

Scores 1,000th Career Goal
NFL

Eli Stowers' Athleticism Should Not be Overshadowed
Nate Schmidt

Exits Early Due to Illness
NFL

Kenyon Sadiq's Low Production at Odds with His Elite Athleticism
Matt Grzelcyk

to Miss Four-Game Road Trip
Mikko Rantanen

to Return to Full Practice
NFL

Carnell Tate Part of a Loaded Ohio State Rookie Class
A.J. Greer

Handed a Three-Game Suspension
Stephon Castle

Iffy for Monday
Bennedict Mathurin

Remains Out Monday
Isaiah Collier

Still Sidelined Monday
Kyle Kuzma

Iffy for Monday Vs. Clippers
Pascal Siakam

May Miss Monday's Game Vs. Orlando
John Collins

Expected to be Available Monday Vs. Bucks
Tristan Vukcevic

Exits Early With Back Tightness
Jonathan Taylor

Still Headlines Colts Backfield
Troy Terry

Wins it for Anahiem
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Ilya Sorokin

Earns Shutout Over Columbus
Jalen Coker

Clock Ticking on Jalen Coker's Buy-Low Window?
Bobby Portis

is Cleared for Monday's Game
Kawhi Leonard

Holds Questionable Tag for Monday
Danny Wolf

Suffers Ankle Injury on Sunday
Killian Hayes

Exits in First Half
Nique Clifford

Exits Early on Sunday
Royce O'Neale

is Ruled Out on Sunday
Kevin Porter Jr.

to Miss Third Straight Game
Collin Murray-Boyles

Remains Out Sunday
Jalen Johnson

Could Miss Second Straight Game
Joel Embiid

Remains Sidelined Monday
Grayson Allen

to Miss Fourth Straight Game
Ethen Frank

Sustains Lower-Body Injury Sunday
Grayson Rodriguez

to Open Season on Injured List
Brett Pesce

Questionable to Return This Season
Stefan Noesen

Done for the Season
Yan Kuznetsov

Misses Fourth Consecutive Game Sunday
Connor Zary

Out Sunday
Mike Trout

Returns on Sunday
Anthony Duclair

Misses Sunday's Game
Ryan Pulock

Unavailable Sunday
Nick Lodolo

Exits Early With a Blister
Jeremy Peña

Astros Not Ruling Out Jeremy Pena for Opening Day
Cristopher Sánchez

Phillies Sign Cristopher Sanchez to a Six-Year Extension
Tyler Reddick

the Clear Favorite at Darlington
Kyle Stowers

Placed on Injured List with Hamstring Strain
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Morgan Geekie

Records Three Assists Against Red Wings
Steven Stamkos

Notches Three Points in Win Over Golden Knights
Cole Caufield

Records Career-High Five Points in Saturday's Win
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
Nikita Kucherov

Takes Over Scoring Lead With Four-Point Effort
Tyler Tucker

Out Week-to-Week
William Byron

Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
Chase Elliott

Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
Joey Logano

May Not Have the Speed to Warrant A Darlington DFS Lineup Spot
Ross Chastain

Should DFS Players Trust Ross Chastain at Darlington?
Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
Seiya Suzuki

Won't be Ready for Opening Day
Gleyber Torres

Clear to Return on Monday
Konnor Griffin

Assigned to Minor-League Camp
Gleyber Torres

Scratched From Lineup on Saturday With Lower-Back Tightness
Tanner Bibee

to Take the Ball on Opening Day
Logan Webb

to Start on Opening Day for Giants
Cristopher Sánchez

Cristopher Sanchez to Start on Opening Day for Phillies
Chris Sale

Braves Name Chris Sale as Their Opening Day Starter
Lerone Murphy

Set For UFC London Main Event
Movsar Evloev

Looks To Remain Unbeaten
Michael Aswell

Jr. An Underdog At UFC London
Luke Riley

Set For UFC London Co-Main Event
Sam Patterson

Looks To Extend His Win Streak
Michael Page

Set For Welterweight Bout
Austen Lane

In Dire Need Of Victory
Iwo Baraniewski

A Favorite At UFC London
Akshay Bhatia

Withdraws From Valspar Championship
CFB

Alberto Mendoza Drawing Positive Reviews at Georgia Tech
CFB

Anthony Colandrea Impressing in Nebraska's Spring Practices
J.J. Spaun

Offers Upside Despite Poor Course History at Innisbrook
Aaron Rai

Looks to Bounce Back at Valspar Championship
Johnny Keefer

Brings Ball-Striking Upside to Valspar Championship
Billy Horschel

a Volatile Play at Valspar Championship
Ben Griffin

Looks to Rebound at the Valspar Championship
Corey Conners

Brings Elite Ball-Striking to Valspar Championship
Xander Schauffele

Trending In The Right Direction For Valspar Championship
Sahith Theegala

Has Shot to Challenge at Valspar Championship
Mackenzie Hughes

Looking to Bounce Back at Valspar Championship
Nicolai Hojgaard

Finding Rhythm For Valspar Championship
Matt Fitzpatrick

Continues Hot Start to 2026 Heading to Valspar Championship
Pierceson Coody

Heads to Valspar Championship Following Two Missed Cuts
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF