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DraftKings Daily Fantasy Basketball Picks (3/25/21): NBA DFS Lineups

The top daily fantasy basketball lineup picks for DraftKings on March 25, 2021. Euan Leith provides NBA DFS analysis and sleeper picks for building optimal DFS rosters.

Happy Thursday, RotoBallers! With the NBA trade deadline coming and going this afternoon, the potential for lineup changes is at its highest point of the season. It is a must to double-check those lineups before the games kick off tonight. Trades, scratches, and buyouts will be happening thick and fast as the deadline draws nearer. Some moves may slip under the radar, and you'll need to turn on those Woj Bomb Twitter notifications to stay ahead of the game.

Injuries are taking their toll across the league. Joel Embiid, LeBron James, Anthony Davis, and Stephen Curry will all sit, and it takes some great talent off the board. My favorite game is the Golden State-Sacramento contest. It's the only matchup where both teams average more than 102 possessions per game, and it will open the door for some terrific fantasy production.

This article will provide you with my daily fantasy basketball lineup picks for DraftKings on 3/25/21. You can also check out today's FanDuel lineup picks. With COVID-19 a significant factor, remember to monitor injury news as the slate can completely change before lineups lock.

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DraftKings DFS Guards

Ben Simmons - PG/SF, PHI at LAL ($8,600)

No Embiid. No James. No Davis. Please give me all the Ben Simmons I can get for tonight's matchup. He's taken on a more prominent role in the 76ers offense, and it's paying off in his counting categories. Over his last four games, the 24-year old is averaging 16.8 points, 9.8 points, 6.8 assists, and a steal in 37.4 minutes.

Another thing in Simmons' favor will be the Laker's recent backcourt defense. They come into the contest as the worst defense versus point guards over their last 15 matchups. This game does have the lowest over/under among the five games (211.5 points), but I'm hoping that will cause some DFS players to fade Simmons. I highly recommend him for tonight's slate and will gladly roster him despite the Vegas indicators.

Kendrick Nunn - PG, MIA vs. POR ($4,600)

The Heat seems to be in every trade rumor on the planet, and it could make their lineup unpredictable for tonight's contest. While Nunn is one of the players that could be on the move, he is well worth a $4,600 investment if he stays in the friendly confines of South Beach. Goran Dragic (back) is injured while also involved in trade rumors. The Slovenian's absence will allow Nunn to build on his positive performance from Tuesday.

The 25-year old logged 35 minutes and tallied 25 points on 5-for-9 shooting from behind the three-point arc. The Trail Blazers defense is third-worst versus point guards over the last 15 games and won't provide much resistance against Nunn and the rest of the Heat's guards tonight.

Damion Lee - SG/SF, GS at SAC ($3,900)

Sometimes you've got to risk it for the biscuit, and that's what I'm doing with Damion Lee in my lineups tonight. While Jordan Poole ($6,100) is the apparent replacement for Curry, I can't resist Lee's boom potential. If he gets the minutes, he will produce. Lee had his best game of the season against Memphis last week with 28 minutes on the court. In that time, he had 21 points, five rebounds, two assists, a block, and a steal with four threes. He cost $3,300 in that game and provided TEN-times his value with 35.75 fantasy points.

Slotting Lee into your lineup will allow DFS players to spend up at a couple of other positions In a stars and scrubs strategy. It's only a five-game slate, and getting some of those studs consolidated into one lineup is more than a viable strategy for tonight's contests.

 

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DraftKings DFS Forwards

Richaun Holmes - PF/C, SAC vs. GS ($7,300)

The Warriors enter this matchup as the fourth-worst defense against centers over their last 15 games, which will equal fantasy success for Richaun Holmes. The 2015 second-round pick is in a great run of form at the moment and set to put up another high fantasy total for his managers. He has five double-doubles in his last seven games, and he will look to make it six of eight against the Warriors.

Since the All-Star break, the 27-year old is averaging 18.1 points, 10.9 rebounds, and 1.9 blocks per game. Add all that production up, and it comes out to 45.7 FPPG. That would be a six-times return on value at his $7,300 salary tonight. Sign me up twice for those kinds of numbers. Holmes is a rock-solid option at the power forward or center spot tonight.

Kyle Kuzma - SF/PF, LAL vs. PHI ($6,900)

LeBron James (ankle) and Anthony Davis (calf) remain sidelined for the Lakers, and it will likely result in a chalkish night for Kuzma. Not all chalk is bad chalk, and the fourth-year forward will be a primary offensive threat for the purple and gold against the 76ers. Last time out, the 25-year old recorded 41.5 fantasy points when he produced 16 points, 10 rebounds, seven assists, one steal, and four threes in 34 minutes.

DFS managers will be hoping for a similar output tonight, but it will be tough against a stout Philly defense. Still, someone has to score and create for the Lakers, and Kuzma is the best candidate for that role. He's averaging 32.1 minutes per game over his last six tilts and is a safe bet to return at least five-times his value on his $6,900 salary.

RJ Barrett - SF, NY vs. WAS ($6,800)

The $6,500-$7,500 range is full of talent at the forward positions tonight, and Barrett is no exception. The second-year player is averaging 35.4 FPPG over his last five games, and his game has taken a step forward during his sophomore season. For the year, Barret is averaging 17.3 points, 6.1 rebounds, and three assists per contest.

While he's only taking 3.3 threes per game, he is still making 34.5 percent of his attempts. The Wizards allow their opponents to make 38.6 percent of their three-point attempts this season, the fourth-worst mark in the league. The Wizards will also force the Knicks to play fast than usual with their league-leading pace. More opportunities and a great matchup will make Barrett a suitable target for your DFS rosters.

 

DraftKings DFS Centers

Mitchell Robinson - C, NY vs. WAS ($5,100)

Well, that didn't take long. In just his second game back from a month-long injury absence, Robinson came through for DFS managers. The 22-year old posted a spectacular stat line with 16 points, 12 rebounds, two assists, and three blocks in 31 minutes. The Wizards are a bottom-seven rebounding team in the league this season, and Robinson should be able to approach double-digits in that category again.

The rebounding-floor and the potential points and blocks-upside for the 2018 draft pick make him an enticing option for Thursday. Throw in that $5,100 price tag, and Robinson is a lock for my lineups.

 



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REAL-TIME FANTASY NEWS

Cal Raleigh

Exits With Apparent Side Injury on Wednesday Night
Juan Soto

X-Rays Come Back Negative on Juan Soto's Ankle
Jacob Misiorowski

Pulled Early With Possible Leg Injury
Juan Soto

Exits Wednesday's Game Early with Ankle Injury
Tim Patrick

Jets Agree to Terms With Veteran Receiver Tim Patrick
Malik Nabers

Undergoes Second Knee Surgery
De'Von Achane

Dolphins, De'Von Achane Agree to Four-Year Contract Extension
Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Jalen Hurts

Can Jalen Hurts Bounce Back as a Rusher in 2026?
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Zach Charbonnet

Dynasty Value in Question Entering 2026
DeVonta Smith

Poised to Reach a New Level of Production in 2026?
Chris Olave

Facing Increased Target Competition in New Orleans Entering 2026
Chris Bell

Dynasty Stock Rising Following NFL Draft
Ted Hurst

Facing Uphill Battle for Playing Time in Tampa Bay
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
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NFL Veteran Tom Moore Joins Iowa Coaching Staff
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Can Cam Cook Dominate in Return to Big 12?
Chris Brazzell II

Is Chris Brazzell II the Top Deep Threat in Carolina's Receiver Room?
Kaelon Black

a Threat to Win Backup RB Job in San Fran?
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ACC, Big 12 Support 24-Team College Football Playoff
De'Zhaun Stribling

to be 49ers' New "F" Receiver?
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Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
Drew Allar

Steelers "Uninstalling" Everything Drew Allar Learned in College
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Kwazi Gilmer Set for Big Impact at Nebraska
Ja'Kobi Lane

Is Ja'Kobi Lane the Pass-Catching Answer the Ravens Have Been Seeking?
Zachariah Branch

Does Zachariah Branch Have a Path to Immediate Production?
Max Klare

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Eli Stowers

the Tight End of the Future in Philadelphia?
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Germie Bernard

Already in a Tough Spot to Hold Dynasty Value
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Denzel Boston

a Smart Bet to Meet or Exceed Value in Dynasty Rookie Drafts
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Matthew Stafford

a Sell Candidate with Touchdown Regression Likely on its Way
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
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Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Jayden Reed

Dynasty Value Tethered to His Underwhelming Usage
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Sidney Crosby

Joins Team Canada for World Championship
Ryan Poehling

Suffers Upper-Body Injury in Game 5 Loss
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Dylan Harper

Cleared for Action Tuesday
De'Aaron Fox

Available for Game 5 Against Timberwolves
Caris LeVert

Remains on Injury Report With Heel Issue
Duncan Robinson

Listed as Questionable for Game 5
Memphis Grizzlies

Brandon Clarke Dies at Age 29
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Sam Malinski

Day-to-Day With Upper-Body Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Artturi Lehkonen

Considered Day-to-Day
Charlie Coyle

Lands Six-Year Extension
Ukko-Pekka Luukkonen

to Start Game 4 Against Canadiens
Drew Helleson

Unavailable for Game 5
Radko Gudas

Still Out Tuesday
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
Luka Dončić

Luka Doncic Admits He Wasn't Close to Returning Before Season Ended
CFB

Isaac Brown Has All-American Upside in 2026
LeBron James

Uncertain About Future After Season-Ending Loss
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
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An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
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Waldo Cortes-Acosta Looks To Extend His Win Streak
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF