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QB vs Pass Rush Matchups To Watch - Week 16

Gage Bridgford (@GbridgfordNFL) identifies quarterbacks to watch in Week 16 based on the opposing pass rush defense. These QBs could be players to fade and avoid or to start and stream in fantasy football leagues.

Week 16 is here, and fantasy championships are on the line. Some teams head into the fantasy finals as big favorites but others are scrapping to pull off a big win as underdogs. Real teams start at quarterback, and the position is pretty important for fantasy as well.

Quarterbacks have changed the game for fantasy football this year with guys like Lamar Jackson and Josh Allen taking full advantage of their running ability to stress defenses. It gives you more viable options on a week-to-week basis.

Right now, these are the weeks that we've spent months preparing and competing for. There's no room for an error, and it's not time to get cute. We have to set our best lineups to win because we aren't coming back next week if we don't.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Look Away Before It Gets Ugly

Jared Goff @ San Francisco 49ers

You're telling me that Los Angeles Rams quarterback Jared Goff has to go on the road in a do-or-die game against one of the best teams in the conference. I don't like his odds. His offensive line has struggled to generate time for their quarterback despite only giving up 21 sacks this season. In the previous matchup between these two teams, Goff was taken down four times. So, one-fifth of his sacks came in one game, and that was at home.

One issue for the San Francisco 49ers Defense is that they're dealing with several injuries to their pass rush. However, they're still trotting out one of the most fearsome fronts in football from Nick Bosa to Arik Armstead and everyone in between. They have 47 sacks on the year, and, with two games remaining, they would have finished as a top-10 team in sacks last season. This group gets after the quarterback, and, in their fight for playoff seeding, they'll be wanting to make a statement on Saturday night.

 

Sam Darnold vs Pittsburgh Steelers

This Pittsburgh Steelers team is not the best in football, but, with the collection of players that they've been trotting out, they're playing far better than anyone would have expected. It's been largely on the back of their defense. They've gotten an NFL best 49 sacks thus far, and they'll likely be adding to that total in Week 16. They control their playoff destiny if they're able to win in each of the final two weeks. Week 17 isn't guaranteed against a hot Baltimore Ravens team, but they can make life a lot easier with a win this week.

New York Jets quarterback Sam Darnold has been hit a lot this year, as the team has given up 48 sacks on the season. He's also been extremely inconsistent. After seeing ghosts against the New England Patriots, he had a hot few games, but they've also lost to two winless teams (at the time) in the Miami Dolphins and Cincinnati Bengals. They're eliminated from playoff contention, and they have nothing to play for other than draft positioning. Additionally, the dynamic between him and head coach Adam Gase will be interesting to watch after their sideline blowup last week.

 

Daniel Jones @ Washington Redskins

First things first, why are the New York Giants playing Daniel Jones (ankle) despite his high ankle sprain? You just spent a first-round pick on the guy, and you're bringing him back literally two weeks after an injury that typically takes multiple weeks to recover from. This offensive line has allowed 38 sacks this season, and his mobility will likely be limited by the injury. New York just lost tight end Evan Engram (foot) for the remainder of the season, and these final two weeks will not be an amazing swan song.

The Washington Redskins have shown life in recent weeks with quarterback Dwayne Haskins under center, and their defense has also shown some improvement. They're fifth in the NFL with 42 sacks, and they want to see what they have in this rookie with the year nearly over. This is an audition for their next head coach whether that is Urban Meyer or someone else. In a battle of two terrible teams in lost seasons, I think Washington gets after Jones early and often.

 

That's More Like It

Gardner Minshew @ Atlanta Falcons

I would like Jaguars quarterback Gardner Minshew a lot more if this were a home game, but, I still like him this week. No longer under the reign of the almighty Tom Coughlin, this Jaguars team is going to come out and make a statement, and a lot of that is going to be by running the ball and throwing against an overmatched Falcons Defense. The Jaguars are in the top half of the NFL in sacks allowed. Additionally, both of his starting wide receivers are expected to be healthy for this dome contest with D.J. Chark apparently over an ankle injury that cost him the previous game.

The Falcons are led by a defensive-minded head coach, but they've been a lot more bark than bite for a few years. This season, they have just 24 sacks through 14 games. The strength of their pass rush is on the inside with stud defensive tackle Grady Jarrett, but the strength of the Jaguars offensive line is on the interior. The matchups aren't in their favor, and, in a sneaky shootout, the odds favor the Jaguars in this one.

 

Kyler Murray @ Seattle Seahawks

Arizona Cardinals quarterback Kyler Murray has performed about as well as one could have hoped entering the year. He has used his running ability to keep his fantasy floor high, and, despite playing behind a struggling offensive line, he gets the ball out to his receivers. The team is averaging about 22 points per game, and they're going to be forced to score a lot against one of the NFL's top-10 offenses.

Thankfully for Murray and Arizona, the Seahawks don't have the fierce pass rush that they had earlier in the decade. They have just 24 sacks this season, and they're giving up over 24 points per game. This defense allows points, and the offense is often tasked with bailing them out. Murray will find his opportunities to score despite his offensive line's struggles.

 

Drew Lock vs Detroit Lions

Fading the Detroit Lions Defense has been a good strategy for most of the year. They don't have any form of a pass rush, and their secondary, outside of veteran cornerback Darius Slay, can't cover anyone. Drew Lock came back to earth last week against a sneaky good Kansas City Chiefs Defense, but he has the matchup to rebound this week. His offensive line has only allowed three sacks in the three games he has played, and the Lions aren't the type of group that could drastically increase that total.

The Lions have 27 sacks this season with 14.0 of those sacks coming from two players in the forms of Trey Flowers and Devon Kennard. Outside of those two, the next-highest player on the team has just two. If Denver can slow down those two, it's going to be next to impossible for Detroit to generate any pressure. Lock isn't an ideal play, but he's far from the worst on this week's slate.

More Weekly Lineup Prep




REAL-TIME FANTASY NEWS

Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
Indianapolis Colts

Daniel Jones Present at OTA Practice on Wednesday
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
Minnesota Vikings

T.J. Hockenson's Dynasty Stock Continues to Trend Down
Minnesota Vikings

Is Jordan Addison a Clear Buy-Low Candidate Ahead of 2026?
Tampa Bay Buccaneers

Cade Otton Continues to Offer Depth in Dynasty Leagues
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
Detroit Lions

Jared Goff Continues to Have Dynasty Appeal at 31 Years Old
Tampa Bay Buccaneers

No Clear Path to Fantasy Relevance for Tez Johnson in Tampa Bay?
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
Zach Ertz

Could Still Contribute in Dynasty Leagues
De'Aaron Fox

Limited to Nine Points in Game 5 Loss
Russell Henley

a Top Option at Colonial
Dyami Brown

Holds Little Dynasty Value in His Return to Washington
Harry Hall

Hoping Putter Carries Him at Colonial
Julian Champagnie

Notches 22 Points With Four Triples Tuesday
Trevor Etienne

Could Still Find Dynasty Relevance After Quiet Rookie Season
Stephon Castle

Leads Spurs in Scoring Tuesday Night
Rickie Fowler

Looks to Regain Momentum at Colonial
Victor Wembanyama

Struggles in Game 5 Loss to Thunder
Bam Knight

Dynasty Value Has Run Dry in Crowded Running Back Room
Alex Caruso

a Difference-Maker Again in Game 5
Pierceson Coody

Looking to Stay Hot at Colonial
Jared McCain

Produces 20 Points in First Playoff Start
Mac Jones

and 49ers Agree to a Revised Contract
Shai Gilgeous-Alexander

Scores Game-High 32 Points in Game 5 Win
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Tory Horton

Could Do Some Stuff "Toward the End of Spring"
Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
MarShawn Lloyd

Sees Short-Term Value Soar
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Bucky Irving

is Expected to be Ready for Training Camp
Zion Williamson

to See More Versatile Role
Parker Washington

Jaguars Think Parker Washington Can Replicate Second-Half Production
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Josh Jacobs

Arrested on Five Charges, Booked Into Jail
Claude Giroux

Planning to Return for 20th NHL Campaign
Josh Sweat

Cardinals Receiving Trade Calls on Josh Sweat
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Tetairoa McMillan

Working With the Training Staff on Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
RANKINGS
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1B
2B
3B
SS
OF
SP
RP

RANKINGS

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