🦃 BLACK FRIDAY - TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Break The Slate: DraftKings NFL DFS Lineup Picks - Week 15

Joe Nicely's DraftKings NFL DFS picks and lineup sleepers for Week 15. His top daily fantasy football recommendations to target for DraftKings DFS contests.

Hi RotoBallers and thanks for joining me for Week 15! We once again have a jam-packed slate that includes a massive nine games with projected point totals of over 45. This means that there are lots of strong options on the board this week, but as a result we can expect very high scores to be needed to win DFS tournaments. Thanks for joining me here at RotoBaller, let's dig in and find some huge scores again this week!

These DraftKings lineup recommendations are based on matchups, projected ownership, overall upside/talent levels, opportunity, and other factors such as Vegas odds, home-field advantage, and more. There are quite a few great plays available, so read on to find out which players are the best for Week 15.

Good luck with your DraftKings DFS lineups, let's Break The Slate together!

Be sure to check all of our fantasy football rankings for 2025:

 

DraftKings DFS Quarterbacks - Week 15 Picks

Deshaun Watson - HOU @ TEN ($6,800)

On paper, this looks like one of the best games to target in DFS tournaments this week, as we have a tight spread, high projected point total, and tons of explosive players on the field. On the Texans side of the ball, Deshaun Watson has as much fantasy upside as any QB in football, as evidenced by his four outings of over 30 DK points. Watson is coming off back-to-back 28-plus point performances and he's in a great spot this week against a Tennessee defense that is 25th in the NFL in yards allowed per pass.

Kyler Murray - CLE @ ARI ($5,600)

This is a great "buy low" opportunity on Arizona's rookie QB Kyler Murray. Murray heads into this home matchup against the Browns at just $5.6k...his lowest DK salary since Week 2 of the season. The price reduction is a result of his pedestrian outings recently against the tough defenses of Pittsburgh and LA, but this game against the Browns offers Murray's most "beatable" matchup since a 30.8-DK point outing against the Bucs in Week 10. To be transparent, Cleveland has been fairly solid against the pass as of late and isn't a secondary that we normally want to go out of our way to target, but the upside his there for Murray at this price, as he's attempted over 30 passes in 11 of 13 games for this high-volume Cards offense.

 

DraftKings DFS Running Backs - Week 15 Picks

Saquon Barkley - MIA @ NYG ($7,700)

This feels like a "now or never" spot for Saquon. There's not any stats behind that analysis, but common sense tells me that Barkley is just simply too good not to produce a big game at some point before this season ends. If (and his recent output makes this a true "if") he is going to do that, there's no better spot than this week against the Miami Dolphins, a team with one of the worst defensive units in the league. Miami has allowed the most rushing yards to RBs in the NFL and New York (in a rarity) is a home favorite against the Dolphins. Barkley is averaging just over 17 carries and almost five targets per game over the Giants last three, and this week presents a matchup in which he should finally be able to capitalize on that volume.

Chris Carson - SEA @ CAR ($7,700)

It's been an up-and-down season for Seahawks RB Chris Carson, as he appeared to have a stranglehold on the job before "fumbling" away the opportunity. Carson's butterfingers brought Rashad Penny firmly into the mix. However, with Penny suffering a season-ending injury last week, Carson should move right back into a bellcow role for Seattle. If we look at his usage from roughly the first 10 games of the season, we can expect at least 20 touches for Carson in this spot against a Panthers Defense that has been slaughtered on the ground. Carolina is DEAD LAST in the league in DK points allowed to the RB position, has allowed 21 rushing TDs to opposing RBs, and is 31st in the NFL in both total rushing yards and yards per carry allowed. Seattle enters every week with a "run first" game plan and that philosophy should especially hold true in this matchup.

Phillip Lindsay - DEN @ KC ($5,800) & Raheem Mostert - ATL @ SF ($5,200)

I wanted to at least touch on these two guys, as they are both well worth consideration in tournaments this week. Both Phillip Lindsay and Raheem Mostert have slate-breaking ability, but both have an extremely unpredictable amount of volume from week to week, so a bet on either/or is a bet on their talent and extreme efficiency. I've been banging the Lindsay drum for several weeks with underwhelming results, but I'm still interested due to his matchup against a Chiefs Defense that is last in the league in DK points allowed to the RB position. As for Mostert, he's basically played his way into playing time by being unbelievably productive with limited opportunities. Niners coach Kyle Shanahan even admitted this week that Mostert has given the team "no choice" but to continue giving him work. I wouldn't go overboard in buying into the "coach speak", but Mostert does draw an intriguing matchup against a Falcons Defense that has been mediocre against running backs, but very bad overall.

 

DraftKings DFS Wide Receivers - Week 15 Picks

Kenny Golladay - TB @ DET ($7,200)

If I'm being honest, I don't love the higher price tag here for Kenny Golladay. However, we are looking for slate breakers, and the Lions wideout has a matchup against the Tampa Bay Bucs that has an excellent chance of producing some DFS fireworks for us. Despite Matt Stafford's absence, Golladay just keeps on rolling. With David Blough stepping in at QB for Detroit's last two, "Baby Tron" has still posted impressive stats, combining for 216 yards and two TDs on 10 catches in Blough's two starts. He gets to tee off against a Bucs defense that strongly funnels volume to the air and ranks DEAD LAST in the NFL in DraftKings points allowed to opposing WRs. With running mate Marvin Jones Jr headed to IR, we should see Golladay get all the work he can handle in this pristine spot.

Darius Slayton - MIA @ NYG ($4,700)

This is our second highlighted Giants player of the week, which is kinda gross in and of itself. However, New York wide receiver Darius Slayton is massively underpriced at just $4.7k this week in a smash spot against the Miami Dolphins. We should be thankful for DK's early pricing, because Slayton's price decreased by $400 on the heels of a huge 35.4-point game on Monday night. The Dolphins are 30th in the NFL in DK points allowed to the WR position and have relinquished 23 receiving TDs to opposing wideouts, the most in the league. Slayton's floor is fairly solid, as he's received target counts of 8/9/7/15 over New York's last four and, as he exhibited in Week 14, he has tournament-winning upside.

Breshad Perriman - TB @ DET ($4,500)

We've already touched on Detroit wide receiver Kenny Golladay in this week's article, but I'm also very interested in the other side of this matchup. As if this Bucs offense wasn't already the perfect setup, they will now be without stud wideout Mike Evans for the remainder of the season. Evans accounted for a huge chunk of usage in this pass-happy system...usage that will be now be inherited by other Bucs pass catchers. The natural inclination here is to head straight for Chris Godwin - and you can definitely do that, so don't feel that I'm low on Godwin - but for the purposes of this article (and salary savings), let's click on Breshad Perriman at just $4.5k. Perriman is a former first-round pick that has bounced around the league over the course of his career, despite possessing obvious athleticism. With Evans out, Perriman will slide into a concrete role beside Godwin as Tampa's number-two receiver. This comes at a time when Perriman has already put together his two best games as a Buc in recent weeks, having combined for 157 yards and a TD on eight catches over Tampa's last two. He draws a dreamy matchup against a Lions secondary that has been routinely torched as of late and has relinquished over 2,300 yards and 13 TDs to the WR position.

 

DraftKings DFS Tight Ends - Week 15 Picks

Zach Ertz - PHI @ WAS ($6,000)

Nothing fancy here, just lots and lots of expected volume for Zach Ertz. With the Philly receiving corps basically non-existent due to a crazy amount of injuries, Ertz is coming off a 13-target game against the Giants last week, his fourth game with double-digit targets over the Eagles last five. His matchup against Washington is soft, as the Redskins stand 24th in the league in DK points allowed to the TE position. This Philly offense hasn't been as potent as we've seen in the past, but Ertz has remained a consistent usage monster and leads the league in TE targets with 119. If you can find the salary to splurge at tight end, he offers a very high floor and always has the potential to pop off for a big outing.

Tyler Higbee - LAR @ CAR ($3,900)

I wrote up Tyler Higbee in this article a couple of weeks ago in advance of his matchup against the Arizona Cardinals, and while Higbee's matchup against Dallas is nowhere near that type of slam dunk, he does remain very viable this week, as he's played unbelievably well in the absence of Gerald Everett. It seems as though this Rams offense has finally realized what they have in Higbee. He's been targeted a massive 19 times in LA's last two games, and has produced to the tune of 14 catches for 223 yards and a TD. This is a "ride the hot hand" type of play and the usage for this Rams offense has been frustratingly sporadic, but the price tag is attractive and the Cowboys Defense does filter targets to tight ends, having allowed the tenth-most DK points in the NFL to the position.

O.J. Howard - TB @ DET ($3,500)

This was supposed to be a monster season for OJ Howard...but things haven't exactly went according to plan for the talented third-year tight end, as Howard has battled injuries that have kept him off the field, ineffectiveness when he does play, and what seems to be a never-ending residence in Coach Bruce Arians' doghouse. However, things might finally be looking up, as he's been targeted five and six times over the Bucs last two games - the most targets he's received over any two-game stretch this season. With Mike Evans now out of the lineup, Tampa might have no choice but to continue and perhaps even increase Howard's usage against a Lions Defense that has been struggling in every aspect. We've been down this road before with Howard, but his price is enticing and he has tournament-winning upside that hasn't been flashed this year.

 

DraftKings DFS Defenses - Week 15 Picks

Seattle Seahawks Defense - SEA @ CAR ($3,700)

Remember when some people thought that Kyle Allen was a superior option to Cam Newton? Yeah...how's that workin' out? Allen has been a human turnover machine over the past month. The second-year QB has fumbled a hard-to-wrap-your-head-around SIX times since Week 10 and has thrown seven picks over the same time frame. It's a great spot for take advantage of with this Seahawks defensive unit that has failed to truly standout, but plays sound, fundamental football.

LA Rams Defense - LAR @ DAL ($2,900)

While everybody has been busy focusing on the Rams offensive issues, their defense has quietly been playing very well. Since Week 10, this Rams D/ST is averaging just under 12 DK points per game. Outside of a 45-point letdown against the Ravens, LA hasn't allowed more than 11 real points since Week 6! They travel to Dallas for a less-than-great matchup, but this Cowboys offense has been visibly sputtering as of late.

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Jameson Williams

Explodes for 144 Yards, Touchdown on Thanksgiving
Dontayvion Wicks

Breaks Out for Two Touchdowns on Thanksgiving
Jordan Love

Lights Up Lions for Four Touchdowns on Thanksgiving
Stephen Curry

Expected To Miss About A Week With Quad Injury
Michael Porter Jr.

Won't Play Friday Versus 76ers
Paul George

Faces Game-Time Call Against Nets
VJ Edgecombe

Sidelined Again Against Nets
Joel Embiid

Out Again Friday vs. Nets
Paolo Banchero

Ruled Out Again Friday With Groin Injury
Jalen Williams

Set to Make Season Debut Friday
Chris Olave

Misses Thursday's Practice
Amon-Ra St. Brown

Will Miss 1-2 Weeks
DeVonta Smith

Off the Injury Report, Cleared for Friday's Game vs. the Bears
Jaxson Dart

Clears Concussion Protocol, Set to Return vs. the Patriots
Amon-Ra St. Brown

Downgraded to Out, Won't Return on Thursday
Daniel Jones

Dealing With Fractured Fibula, Will Play Through it
Jonathan Kuminga

Hoping to Return on Saturday Versus Pelicans
Stephen Curry

to Undergo an MRI
Josh Jacobs

Feels Close to 100%
Brady Tkachuk

Aims to Return Friday
Matthew Tkachuk

Resumes Skating
Jakob Chychrun

Stretches Point Streak to Nine Games
Matej Blumel

Expected to Miss Some Time
Marcus Foligno

Exits With Injury Wednesday
Jaden Schwartz

Suffers Lower-Body Injury Wednesday
Trendon Watford

to Sit Out at Least Two Weeks
Gradey Dick

Injured on Wednesday
RJ Barrett

to Be Re-Evaluated in One Week
Anthony Davis

on the Cusp of Returning
Gary Payton II

Hurt in Wednesday's Loss
Stephen Curry

Diagnosed With Quadriceps Contusion
Alvin Kamara

Doesn't Practice on Wednesday
Lukas Dostal

Out Wednesday Night
Sean Durzi

Available Against Canadiens
Thomas Chabot

to Remain Out Wednesday
Jared McCann

Expected to Rejoin Kraken Lineup Wednesday
Andre Burakovsky

a Game-Time Decision Wednesday
Zach Edey

Good to Go Versus New Orleans
Mikko Rantanen

Returns to Stars Lineup Wednesday
J.K. Dobbins

Could Return Later This Season
Shai Gilgeous-Alexander

Available on Wednesday
Mark Stone

Ready to Return Wednesday
Nikola Jović

Nikola Jovic Good to go on Wednesday
Dylan Cease

Agrees With Blue Jays on Seven-Year, $210 Million Deal
Norman Powell

Back in Action Wednesday
Giannis Antetokounmpo

Ruled Out on Wednesday Evening
Andrew Wiggins

Will Suit Up Against Milwaukee
Terry McLaurin

Plans to Play on Sunday Night
Anthony Rendon

Angels Could Buy Out Final Year of Anthony Rendon's Contract
Brandon Aiyuk

49ers Won't Open Brandon Aiyuk's Practice Window This Week
Joe Burrow

Bengals Officially Activate Joe Burrow for a Return on Thanksgiving
C.J. Stroud

Practicing Wednesday
Trey Benson

Spotted at Practice on Wednesday
Marvin Harrison Jr.

Back at Practice Wednesday
DeVonta Smith

Missing From Practice Again on Wednesday
Josh Hader

Says his Shoulder is "Back to Normal"
Ketel Marte

Diamondbacks "Actively Listening" on Ketel Marte
Jaxson Dart

to be a Full Participant at Wednesday's Practice
Dalton Kincaid

has "a Chance" to Play in Week 13
Josh Norris

Nearing Return
Kevin Lankinen

Not Traveling With Canucks
Zach Werenski

Escapes Serious Injury, May Play Wednesday
Auston Matthews

Could Be an Option Wednesday
Jason Robertson

Scores in Seventh Consecutive Game
Wyatt Johnston

Ends Dry Spell With Four-Point Performance
Vinnie Hinostroza

to Miss 4-6 Weeks
Pyotr Kochetkov

Dealing With Undisclosed Injury
J.T. Realmuto

Red Sox Showing Interest in J.T. Realmuto
Sonny Gray

Red Sox Acquire Sonny Gray From the Cardinals
CFB

Jeremiah Smith, Makai Lemon, Skyler Bell Named Biletnikoff Award Finalists
Shohei Ohtani

to Play for Team Japan in 2026 World Baseball Classic
Colorado Rockies

Warren Schaeffer to Stick Around as Rockies Manager in 2026
CFB

Chris Bell Out for Rivalry Matchup Against Kentucky
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Alonzo Menifield

Suffers First-Round Knockout Loss
Volkan Oezdemir

Gets Back In The Win Column
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
Waldo Cortes-Acosta

Shines At UFC Qatar
Tagir Ulanbekov

Suffers Third-Round Submission Loss
Kyoji Horiguchi

Makes Triumphant UFC Return

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP