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DraftKings Daily Fantasy Baseball Picks (5/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on May 21, 2018. Adam Meyer's MLB DFS analysis and sleepers for building optimal DFS rosters.

It's a short nine-game slate on Monday. Two games have an over/under of at least nine total runs. Five teams are heavy favorites (-185): STL, MIN, NYY, LAD, and WSH. However, while you would think pitching would be loaded, the player pool isn't elite.
On a positive note, weather shouldn't be an issue for Monday. The weekend was full of rain and caused headaches for us all.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @CharlieSideHstl.

DraftKings Starting Pitchers

Walker Buehler, LAD (vs. COL) - $9,300

The MLB team with the lowest runs scored in 2018 was able to produce four earned runs against Buehler in his last start (@ MIA). While that news is somewhat alarming, Buehler still managed to strike out seven batters, continuing his streak of at least five Ks per appearance this season. The Rockies are next for Buehler. Colorado has struck out the seventh-most times this season (426). The Rockies are also 27th in team wOBA against right-handed pitchers (.294). From a Vegas point-of-view, the COL/LAD matchup has the lowest over/under on the slate (seven total runs) and the Dodgers are one of the strongest favorites of the ticket (-180). Both odds are in favor of Buehler.

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Jose Berrios, MIN (vs. DET) - $8,500

It’s a mixed bag when it comes to Berrios and his stat lines. He’s been known to strike out 11 batters in a game, or strikeout none. He’s produced three shutouts in 2018, and allowed five earned runs in three starts this year. However, on a slate this small, without strong pitching prospects, I’d roll the dice on Berrios. His opponent, the Tigers, are 26th in team wOBA against righties (.295) and Vegas has given Minnesota the strongest odds to win on Monday (-200).

 

DraftKings Infielders

C - Gary Sanchez, NYY (@ TEX) - $4,800

After an amazing 4-for-5 performance where Sanchez smacked two home runs in Kansas City, he was given the day off. Now, he’ll look to return to action and continue his hot streak. In the past week, Sanchez is 5-for-11 (.455) with two doubles and two home runs. Sanchez is also third on the team in ISO against right-handed pitchers (.262).

1B - Trey Mancini, BAL (@ CWS) - $3,800

I wanted to wait and see who got the nod for some lineups before I locked in my post for Monday. First base can always be a crucial spot to build, when adding power-hitters to your DFS lineup. I tend to lean towards home running hitting options in this position. Mancini is only 2-for-11 (.111) in the past week, but he's homered three times in the last 10 games. Also, his Orioles are projected to score 4.9 runs (fourth-most) against the White Sox.

2B - Brian Dozier, MIN (vs. DET) - $3,900

Here’s another cold bat that you may not be thrilled with, at first. Dozier is 1-for-21 (.048) in the past week, but his proficiency against lefties is still profitable to the DFS community. He leads the team with a .280 ISO against left-handed pitchers (since 2017). When you get a combination of high ISO, with a leadoff hitter (high in the order), and a reasonable price tag you add them to your DK roster.

3B - Anthony Rendon, WSH (vs. SD) - $3,800

Sure, if you add Rendon with the past two selections you get 3-for-44 (.068) in the last seven days. Rendon is 1-for-12 (.083) in the past week. However, all three are solid selections against southpaws. Rendon leads the Nationals with a .320 ISO against left-handed pitchers.

SS - Didi Gregorius, NYY (@ TEX) - $3,900

I swear these are my suggestions for Monday and not an All-Star team of struggling batters. Gregorius is oh-fer in the past week (0-for-7), but again, the ISO doesn't lie. Even with his recent slump, Gregorius still owns a solid ISO against right-handed pitchers since 2017 (.246). Hopefully, this minor rest (hasn't played since Friday) is enough to wake up his bat and return him to his April numbers (.330 AVG, 10 HR, and 30 RBI).

DraftKings Outfielders

Tommy Pham, STL (vs. KC) - $4,600

The Cardinals have the third-highest implied run total for the Monday slate (5.1 runs). Compared to the previously mentioned bats, Pham is phenomenal. He's batting .280 (7-for-25) with one home run and one double in the past week. He's also tallied at least two hits in three of the past five games. Pham has also produced a .306 AVG against right-handed pitchers this season. His .207 ISO against righties also adds to his case.

Aaron Hicks, NYY (@ TEX) - $3,800

Sometimes you need to be creative when adding players from lineups with high implied run totals. While some DFS players will flock to Aaron Judge and Giancarlo Stanton, we need to pivot to cheaper options, like Hicks. His .205 ISO against righties is only seventh-best on New York, but it's in the range we like to use (.200 or better). Hicks is hitting .467 (7-for-15) with one triple and one home run in the past week.

Marcell Ozuna, STL (vs. KC) - $3,300

Ozuna has gone hitless in his last five games, but he still leads the Cardinals with a .226 ISO against right-handed pitchers. As I mentioned in Pham's write-up, St. Louis has the third-highest implied run total on the board. So, gathering as many hitters from the Cardinals is a wise decision. Ozuna's price tag fits the bill for our circumstances.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Grayson Allen

Sidelined For Sixth Straight Game
Dylan Harper

Nearing Return From Calf Strain
Josh Norris

Nearing Return
Kevin Lankinen

Not Traveling With Canucks
Zach Edey

Status In Doubt Ahead Of Pelicans Matchup
Zach Werenski

Escapes Serious Injury, May Play Wednesday
Auston Matthews

Could Be an Option Wednesday
Neemias Queta

Ruled Out For Wednesday's Contest
Jason Robertson

Scores in Seventh Consecutive Game
Wyatt Johnston

Ends Dry Spell With Four-Point Performance
Jaime Jaquez Jr.

May Skip Wednesday's Contest
Andrew Wiggins

Questionable Wednesday
Norman Powell

Expected to Return Wednesday
Shaedon Sharpe

Uncertain for Wednesday
Giannis Antetokounmpo

Listed as Questionable for Wednesday
Shai Gilgeous-Alexander

In Danger of Missing Wednesday's contest
Trendon Watford

Won't Return to NBA Cup Meeting with Orlando
Corey Kispert

Suffers Thumb Injury on Tuesday Night
DeVonta Smith

Listed as DNP on Tuesday
Vinnie Hinostroza

to Miss 4-6 Weeks
Pyotr Kochetkov

Dealing With Undisclosed Injury
Tristan Jarry

Expected to Be Available Wednesday
Evgenii Dadonov

Doubtful for Wednesday
J.T. Miller

Joins Team for Road Trip
Joel Kiviranta

Ready to Return Wednesday
Ryan Nugent-Hopkins

Expected to Return on Saturday
Marvin Bagley III

Ruled Out Versus Atlanta
Luke Kennard

Available on Tuesday Night
RJ Barrett

Unavailable Wednesday
Landry Shamet

Out for Wednesday
Nikola Jović

Nikola Jovic Questionable for Wednesday's Matchup With Milwaukee
Bogdan Bogdanović

Bogdan Bogdanovic Considered Questionable for Tuesday
Jauan Jennings

Won't be Suspended
Draymond Green

Will be Questionable for Wednesday Against the Rockets
Goga Bitadze

Downgraded to Questionable
Dereck Lively II

Will Miss At Least 7-10 Days
Omarion Hampton

Chargers Open Omarion Hampton's Practice Window
Lamar Jackson

Returns to Practice
DK Metcalf

D.K. Metcalf Will Be Limited Early in the Week
Isiah Pacheco

Set to Return on Thursday
J.T. Realmuto

Red Sox Showing Interest in J.T. Realmuto
Sonny Gray

Red Sox Acquire Sonny Gray From the Cardinals
Brian Thomas Jr.

Expected to Make his Return in Week 13
Aaron Rodgers

Steelers Have "Great Optimism" Aaron Rodgers Will Play in Week 13
CFB

Jeremiah Smith, Makai Lemon, Skyler Bell Named Biletnikoff Award Finalists
Jayden Daniels

has Been Throwing, Return Timeline Unclear
NFL

As Many as Three NFL Teams Could Have Interest in Hiring Bill Belichick
Sam Reinhart

Extends Scoring Streak With Three-Point Effort
Adam Fox

Delivers Two Assists in Monday's Win
Brandon Hagel

Tallies Three Points Against Flyers
Andrei Vasilevskiy

Extends Winning Streak With Shutout Performance
Logan Cooley

Erupts for Five Points in Monday's Win
Mathieu Olivier

Sustains Upper-Body Injury Monday
Zach Werenski

Hurt Against Capitals
Isiah Pacheco

Targeting a Return on Thursday
Shohei Ohtani

to Play for Team Japan in 2026 World Baseball Classic
Lamar Jackson

Now Dealing With a Toe Injury
Jake Walman

to Remain Out Tuesday
Baker Mayfield

Dealing With Low-Grade Shoulder Sprain
Chris Godwin

Buccaneers Plan to "Ramp Up" Chris Godwin's Usage
Colorado Rockies

Warren Schaeffer to Stick Around as Rockies Manager in 2026
Ashton Jeanty

Ankle Injury isn't Severe
Jayden Daniels

to Practice This Week, Considered a Long Shot for Week 13
C.J. Stroud

Remains in Concussion Protocol
Mike Evans

Could Return Before End of Regular Season
J.J. McCarthy

in Concussion Protocol
Tyrod Taylor

to Remain the Jets' Starting QB
Shedeur Sanders

to Make Another Start for Browns in Week 13
CFB

Chris Bell Out for Rivalry Matchup Against Kentucky
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Alonzo Menifield

Suffers First-Round Knockout Loss
Volkan Oezdemir

Gets Back In The Win Column
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
Waldo Cortes-Acosta

Shines At UFC Qatar
Tagir Ulanbekov

Suffers Third-Round Submission Loss
Kyoji Horiguchi

Makes Triumphant UFC Return
Adolis García

Rangers Non-Tender Adolis Garcia on Friday
CFB

Beau Pribula Expected to Start Against Oklahoma
Dan Hooker

An Underdog At UFC Qatar
Arman Tsarukyan

Looks To Extend His Win Streak
Ian Machado Garry

A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
Alonzo Menifield

Looks For His Third Consecutive Win
Volkan Oezdemir

Looks To Get Back In The Win Column
Myktybek Orolbai

Looks To Win Back-To-Back Fights
Jack Hermansson

Makes His Welterweight Debut
Kyoji Horiguchi

Returns To The UFC
Elly De La Cruz

Played Through Partially Torn Quad to End 2025
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP