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DraftKings Daily Fantasy Baseball Picks (5/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on May 21, 2018. Adam Meyer's MLB DFS analysis and sleepers for building optimal DFS rosters.

It's a short nine-game slate on Monday. Two games have an over/under of at least nine total runs. Five teams are heavy favorites (-185): STL, MIN, NYY, LAD, and WSH. However, while you would think pitching would be loaded, the player pool isn't elite.
On a positive note, weather shouldn't be an issue for Monday. The weekend was full of rain and caused headaches for us all.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @CharlieSideHstl.

DraftKings Starting Pitchers

Walker Buehler, LAD (vs. COL) - $9,300

The MLB team with the lowest runs scored in 2018 was able to produce four earned runs against Buehler in his last start (@ MIA). While that news is somewhat alarming, Buehler still managed to strike out seven batters, continuing his streak of at least five Ks per appearance this season. The Rockies are next for Buehler. Colorado has struck out the seventh-most times this season (426). The Rockies are also 27th in team wOBA against right-handed pitchers (.294). From a Vegas point-of-view, the COL/LAD matchup has the lowest over/under on the slate (seven total runs) and the Dodgers are one of the strongest favorites of the ticket (-180). Both odds are in favor of Buehler.

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Jose Berrios, MIN (vs. DET) - $8,500

It’s a mixed bag when it comes to Berrios and his stat lines. He’s been known to strike out 11 batters in a game, or strikeout none. He’s produced three shutouts in 2018, and allowed five earned runs in three starts this year. However, on a slate this small, without strong pitching prospects, I’d roll the dice on Berrios. His opponent, the Tigers, are 26th in team wOBA against righties (.295) and Vegas has given Minnesota the strongest odds to win on Monday (-200).

 

DraftKings Infielders

C - Gary Sanchez, NYY (@ TEX) - $4,800

After an amazing 4-for-5 performance where Sanchez smacked two home runs in Kansas City, he was given the day off. Now, he’ll look to return to action and continue his hot streak. In the past week, Sanchez is 5-for-11 (.455) with two doubles and two home runs. Sanchez is also third on the team in ISO against right-handed pitchers (.262).

1B - Trey Mancini, BAL (@ CWS) - $3,800

I wanted to wait and see who got the nod for some lineups before I locked in my post for Monday. First base can always be a crucial spot to build, when adding power-hitters to your DFS lineup. I tend to lean towards home running hitting options in this position. Mancini is only 2-for-11 (.111) in the past week, but he's homered three times in the last 10 games. Also, his Orioles are projected to score 4.9 runs (fourth-most) against the White Sox.

2B - Brian Dozier, MIN (vs. DET) - $3,900

Here’s another cold bat that you may not be thrilled with, at first. Dozier is 1-for-21 (.048) in the past week, but his proficiency against lefties is still profitable to the DFS community. He leads the team with a .280 ISO against left-handed pitchers (since 2017). When you get a combination of high ISO, with a leadoff hitter (high in the order), and a reasonable price tag you add them to your DK roster.

3B - Anthony Rendon, WSH (vs. SD) - $3,800

Sure, if you add Rendon with the past two selections you get 3-for-44 (.068) in the last seven days. Rendon is 1-for-12 (.083) in the past week. However, all three are solid selections against southpaws. Rendon leads the Nationals with a .320 ISO against left-handed pitchers.

SS - Didi Gregorius, NYY (@ TEX) - $3,900

I swear these are my suggestions for Monday and not an All-Star team of struggling batters. Gregorius is oh-fer in the past week (0-for-7), but again, the ISO doesn't lie. Even with his recent slump, Gregorius still owns a solid ISO against right-handed pitchers since 2017 (.246). Hopefully, this minor rest (hasn't played since Friday) is enough to wake up his bat and return him to his April numbers (.330 AVG, 10 HR, and 30 RBI).

DraftKings Outfielders

Tommy Pham, STL (vs. KC) - $4,600

The Cardinals have the third-highest implied run total for the Monday slate (5.1 runs). Compared to the previously mentioned bats, Pham is phenomenal. He's batting .280 (7-for-25) with one home run and one double in the past week. He's also tallied at least two hits in three of the past five games. Pham has also produced a .306 AVG against right-handed pitchers this season. His .207 ISO against righties also adds to his case.

Aaron Hicks, NYY (@ TEX) - $3,800

Sometimes you need to be creative when adding players from lineups with high implied run totals. While some DFS players will flock to Aaron Judge and Giancarlo Stanton, we need to pivot to cheaper options, like Hicks. His .205 ISO against righties is only seventh-best on New York, but it's in the range we like to use (.200 or better). Hicks is hitting .467 (7-for-15) with one triple and one home run in the past week.

Marcell Ozuna, STL (vs. KC) - $3,300

Ozuna has gone hitless in his last five games, but he still leads the Cardinals with a .226 ISO against right-handed pitchers. As I mentioned in Pham's write-up, St. Louis has the third-highest implied run total on the board. So, gathering as many hitters from the Cardinals is a wise decision. Ozuna's price tag fits the bill for our circumstances.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Nick Scott

Panthers Re-Sign Safety Nick Scott to One-Year Deal
Nico Hischier

has Four-Point Performance on Saturday
Kene Nwangwu

Jets Re-Sign Kene Nwangwu
Seiya Suzuki

Leaves WBC Game on Saturday With Right-Knee Discomfort
Macklin Celebrini

Continues to Dominate With Three Points
Anze Kopitar

Becomes All-Time Leading Scorer for Kings
Linus Ullmark

Posts Shutout Against Ducks
Travis Hunter

Is Travis Hunter Now an IDP-Only Asset?
Blake Corum

Does Blake Corum Have Standalone Flex Value?
Mo Alie-Cox

Re-Signing with Colts
Jaxson Dart

to Benefit from Improved Weaponry in Year 2
Darnell Mooney

Signing with Giants on One-Year Deal
Zach Neto

is Removed After Suffering Hand Injury
TB

Nicholas Paul Rejoins Lightning Lineup
Cole Caufield

Cleared to Play Saturday
Alex Tuch

Set to Return Saturday
Bobby Brink

Remains Out Saturday
J.T. Miller

Returns to Action Saturday
Joe Ryan

Won't Pitch in the World Baseball Classic
Courtland Sutton

Will Courtland Sutton Lose Targets to Younger Teammates?
Rashee Rice

Looking to Return to Rookie Form?
Omarion Hampton

Has High Upside with New Offensive Coordinator
Trey Lance

Returns to the Chargers on a One-Year Deal
A.J. Brown

Rams Out on A.J. Brown, Trade to Patriots Likely?
Calvin Ridley

Restructures Deal with Titans
Jonathan Taylor

Is Jonathan Taylor Being Undervalued in Dynasty?
Tony Pollard

Can Tony Pollard Keep the RB1 Spot for Titans?
David Montgomery

Has Contract Updated by Texans
Zack Wheeler

Throws First Live BP Session on Saturday
Chris Godwin Jr.

Can Chris Godwin Jr. be the Buccaneers' WR1?
LeQuint Allen Jr.

Can LeQuint Allen Jr. Emerge as the Primary Receiving Back in Jacksonville?
Isaiah Davis

Appears Buried on the Jets Running Back Depth Chart
Merrill Kelly

Expected to Open Season on the Injured List
Christian Kirk

Dynasty Value is Fading Heading into 2026
Anthony Richardson Sr.

Packers Interested in Acquiring Anthony Richardson Sr.?
Kevin Gausman

Named Toronto's Opening Day Starter
Kyle Stowers

Back in Grapefruit League Lineup
Kevin Porter Jr.

Questionable Against Hawks
Devin Carter

Out Saturday Against Clippers
Russell Westbrook

Set to Return Against Clippers
Derrick White

Expected to Play Saturday Against Wizards
Michael Porter Jr.

Likely to Miss Second Straight Game
Nicolas Claxton

to Rest Saturday Against Philadelphia
Ace Bailey

Leaves Friday's Game Early with Concussion
Radko Gudas

Handed a Five-Game Suspension
Auston Matthews

to Miss Rest of Season
Emil Heineman

Scores Twice Against the Kings
Joel Hofer

Shuts Down the Oilers
Giannis Antetokounmpo

Could Miss Saturday's Game Vs. Hawks
Keegan Murray

to Be Re-Evaluated in Two Weeks
Aaron Gordon

Expected Back Saturday Vs. Lakers
Jamal Murray

Expected to Suit Up Saturday
Collin Sexton

to Miss Third Straight Game
Jalen Smith

is Ruled Out for Friday's Game
Robert Williams III

is Unavailable for Friday's Contest
Draymond Green

is Downgraded to Out on Friday
De'Anthony Melton

to Play on Friday
Ayo Dosunmu

is Cleared for Friday's Game
Anthony Edwards

is Available on Friday
Norman Powell

is Tagged as Questionable for Saturday
Victor Wembanyama

Questionable Saturday Vs. Hornets
Andrew Wiggins

to Miss Fifth Straight Game
Francisco Lindor

Takes Full Batting Practice on Friday
Brandon Woodruff

Still TBD for Opening Day
Trevor Rogers

to Start on Opening Day for Orioles
Kevin Vallejos

Looks To Remain Undefeated In The UFC
Josh Emmett

In Dire Need Of Victory
Gillian Robertson

A Favorite At UFC Vegas 114
Amanda Lemos

Set For Co-Main Event
Oumar Sy

Looks To Win Back-To-Back Fights
Ion Cutelaba

Looks To Get Back In The Win Column
Nathan MacKinnon

Racks Up Four Points in Victory Over Kraken
Alexis Lafrenière

Alexis Lafreniere Stays Hot in Winnipeg
Semyon Varlamov

Won't Return This Season
Alexander Romanov

Could Return for Playoffs
Declan Carlile

Hurt on Thursday Night
Wyatt Kaiser

Sustains Upper-Body Injury Thursday
Erik Gudbranson

Could Be an Option Saturday
Auston Matthews

Exits Game With Injury
Blake Snell

Around Six Weeks From Being Fully Built Up
Zack Wheeler

to Face Hitters in Live Batting Practice on Saturday
Gerrit Cole

Could Pitch in a Spring Game Next Week
Matthew Boyd

Named the Cubs' Opening Day Starter
Francisco Lindor

Remains on Schedule for Opening Day
Bryce Miller

Shuts Down Bullpen Due to More Oblique Discomfort
Zac Gallen

Named Arizona's Opening Day Starter
Kyle Teel

Could Miss 4-6 Weeks With Hamstring Strain
Hideki Matsuyama

Brings Strong Course History to TPC Sawgrass
Josh Hader

to Start the Year on the Injured List
Adam Scott

in Strong Form Ahead of The Players
Kyle Teel

Exits Tuesday's Game With Hamstring Injury
Rickie Fowler

on Quite the Run Heading to TPC Sawgrass
Sepp Straka

Needs to Forget What Happened Sunday at Bay Hill
Jordan Spieth

an Enigma Heading to The Players Championship
Justin Rose

Trying to Pick Up the Pieces in Florida
Maverick McNealy

Bounces Back at Arnold Palmer Invitational
Brooks Koepka

Continues His Florida Swing With Some Momentum
Nicolai Hojgaard

in Strong Form Ahead of The Players
Robert MacIntyre

a Volatile Option at The Players
Matt Fitzpatrick

Looks to Return to Top Form at The Players
Sam Burns

a High-Risk, High-Reward Option at The Players
Keegan Bradley

Hard to Trust at The Players
Xander Schauffele

Rounding into Form Heading to Players Championship
Rory McIlroy

Set to Return at Players Championship to Defend Title
Jake Knapp

Set to Return at Players Championship
Viktor Hovland

Continues Strong Start to 2026 Season
Rasmus Hojgaard

Looking for Bounce-Back at Players Championship
Tommy Fleetwood

Will Need to Find Putter to Compete at Players Championship
Akshay Bhatia

Continues Improving Heading to Players Championship
Merrill Kelly

Set to Make Spring Training Debut on Friday
Justin Thomas

Continues Competitive Return at The Players Championship
Max Holloway

Drops Decision At UFC 326
Charles Oliveira

Becomes The New BMF Champion
Caio Borralho

Bounces Back
Reinier de Ridder

Reinier De Ridder Loses Back-To-Back Fights
Rob Font

Gets Dominated
Raul Rosas Jr.

Extends His Win Streak
Michael Johnson

Suffers Second-Round Knockout Loss
Drew Dober

Knocks Out Michael Johnson
Ryan Blaney

Earns his Second Consecutive Phoenix Cup Series Win
Christopher Bell

Falls Short of Victory Despite Dominating at Phoenix
Kyle Larson

Earns Hard-Fought Finish of Third at Phoenix
Denny Hamlin

Quietly Gains Another Top-Five Finish at Phoenix
Joey Logano

Crashes out at Phoenix Despite Strong Run
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF