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DraftKings Daily Fantasy Baseball Picks (5/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on May 21, 2018. Adam Meyer's MLB DFS analysis and sleepers for building optimal DFS rosters.

It's a short nine-game slate on Monday. Two games have an over/under of at least nine total runs. Five teams are heavy favorites (-185): STL, MIN, NYY, LAD, and WSH. However, while you would think pitching would be loaded, the player pool isn't elite.
On a positive note, weather shouldn't be an issue for Monday. The weekend was full of rain and caused headaches for us all.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @CharlieSideHstl.

DraftKings Starting Pitchers

Walker Buehler, LAD (vs. COL) - $9,300

The MLB team with the lowest runs scored in 2018 was able to produce four earned runs against Buehler in his last start (@ MIA). While that news is somewhat alarming, Buehler still managed to strike out seven batters, continuing his streak of at least five Ks per appearance this season. The Rockies are next for Buehler. Colorado has struck out the seventh-most times this season (426). The Rockies are also 27th in team wOBA against right-handed pitchers (.294). From a Vegas point-of-view, the COL/LAD matchup has the lowest over/under on the slate (seven total runs) and the Dodgers are one of the strongest favorites of the ticket (-180). Both odds are in favor of Buehler.

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Jose Berrios, MIN (vs. DET) - $8,500

It’s a mixed bag when it comes to Berrios and his stat lines. He’s been known to strike out 11 batters in a game, or strikeout none. He’s produced three shutouts in 2018, and allowed five earned runs in three starts this year. However, on a slate this small, without strong pitching prospects, I’d roll the dice on Berrios. His opponent, the Tigers, are 26th in team wOBA against righties (.295) and Vegas has given Minnesota the strongest odds to win on Monday (-200).

 

DraftKings Infielders

C - Gary Sanchez, NYY (@ TEX) - $4,800

After an amazing 4-for-5 performance where Sanchez smacked two home runs in Kansas City, he was given the day off. Now, he’ll look to return to action and continue his hot streak. In the past week, Sanchez is 5-for-11 (.455) with two doubles and two home runs. Sanchez is also third on the team in ISO against right-handed pitchers (.262).

1B - Trey Mancini, BAL (@ CWS) - $3,800

I wanted to wait and see who got the nod for some lineups before I locked in my post for Monday. First base can always be a crucial spot to build, when adding power-hitters to your DFS lineup. I tend to lean towards home running hitting options in this position. Mancini is only 2-for-11 (.111) in the past week, but he's homered three times in the last 10 games. Also, his Orioles are projected to score 4.9 runs (fourth-most) against the White Sox.

2B - Brian Dozier, MIN (vs. DET) - $3,900

Here’s another cold bat that you may not be thrilled with, at first. Dozier is 1-for-21 (.048) in the past week, but his proficiency against lefties is still profitable to the DFS community. He leads the team with a .280 ISO against left-handed pitchers (since 2017). When you get a combination of high ISO, with a leadoff hitter (high in the order), and a reasonable price tag you add them to your DK roster.

3B - Anthony Rendon, WSH (vs. SD) - $3,800

Sure, if you add Rendon with the past two selections you get 3-for-44 (.068) in the last seven days. Rendon is 1-for-12 (.083) in the past week. However, all three are solid selections against southpaws. Rendon leads the Nationals with a .320 ISO against left-handed pitchers.

SS - Didi Gregorius, NYY (@ TEX) - $3,900

I swear these are my suggestions for Monday and not an All-Star team of struggling batters. Gregorius is oh-fer in the past week (0-for-7), but again, the ISO doesn't lie. Even with his recent slump, Gregorius still owns a solid ISO against right-handed pitchers since 2017 (.246). Hopefully, this minor rest (hasn't played since Friday) is enough to wake up his bat and return him to his April numbers (.330 AVG, 10 HR, and 30 RBI).

DraftKings Outfielders

Tommy Pham, STL (vs. KC) - $4,600

The Cardinals have the third-highest implied run total for the Monday slate (5.1 runs). Compared to the previously mentioned bats, Pham is phenomenal. He's batting .280 (7-for-25) with one home run and one double in the past week. He's also tallied at least two hits in three of the past five games. Pham has also produced a .306 AVG against right-handed pitchers this season. His .207 ISO against righties also adds to his case.

Aaron Hicks, NYY (@ TEX) - $3,800

Sometimes you need to be creative when adding players from lineups with high implied run totals. While some DFS players will flock to Aaron Judge and Giancarlo Stanton, we need to pivot to cheaper options, like Hicks. His .205 ISO against righties is only seventh-best on New York, but it's in the range we like to use (.200 or better). Hicks is hitting .467 (7-for-15) with one triple and one home run in the past week.

Marcell Ozuna, STL (vs. KC) - $3,300

Ozuna has gone hitless in his last five games, but he still leads the Cardinals with a .226 ISO against right-handed pitchers. As I mentioned in Pham's write-up, St. Louis has the third-highest implied run total on the board. So, gathering as many hitters from the Cardinals is a wise decision. Ozuna's price tag fits the bill for our circumstances.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Troy Terry

Adds Three Points in Return to Lineup
Leo Carlsson

Picks Up Trio of Points on Sunday
Dejounte Murray

Battling Illness Ahead of Monday
Alperen Sengün

Alperen Sengun Could Miss Another Game Monday
Noah Clowney

Sidelined Monday Versus Trail Blazers
Michael Porter Jr.

to Miss Third Straight Game
José Ramírez

Jose Ramirez is Day-to-Day with Shoulder Inflammation
Alexandre Sarr

Out Monday Against Golden State
Jeremy Sochan

Returns to Action Sunday
Ömer Yurtseven

Omer Yurtseven Set to Debut Sunday for Golden State
Quinten Post

Cleared to Play Sunday Against New York
Malik Monk

to Miss Third Straight Game Sunday
Devin Carter

Sidelined Sunday Versus Utah
Brendan Gallagher

Rejoins Canadiens Lineup Sunday
Russell Westbrook

Won't Play Sunday Versus Jazz
Josh Hart

Cleared to Play Sunday Against Golden State
Daniil Tarasov

Starting Against Kraken
Quinn Ewers

Set to Back Up New Quarterback
Ty Emberson

Remains Out Sunday
Chris Brooks

the Preferred Handcuff in Green Bay?
Bobby Brink

Questionable Sunday
Kendre Miller

Continues to Fall Out of Favor in New Orleans
Oliver Ekman-Larsson

Unavailable Against Wild
Brashard Smith

Ascension Put on Pause?
Ryan Nugent-Hopkins

a Game-Time Call Sunday
Corbin Carroll

to Resume Playing Defense This Week
John Carlson

Set for Ducks Debut
Francisco Lindor

Non-Committal About Status for Opening Day
Nathan Eovaldi

Named Rangers' Opening Day Starter
Hayden Birdsong

Diagnosed with Grade 2 Forearm Strain and UCL Sprain
Jacksonville Jaguars

Jaguars Eyeing Defensive Linemen and a Tight End in the NFL Draft?
Davante Adams

Rams Explored Trading Davante Adams
Dallas Goedert

Eagles Bring Back Dallas Goedert on a One-Year Deal
Marvin Harrison Jr.

Continues to Disappoint in Year 2
Theo Johnson

Facing Increased Competition in New York
Kyle Monangai

Will Continue to Test Fantasy Managers' Patience
Jayden Daniels

' Suppressed Dynasty Value Makes him a Buy-Low Candidate
Zay Flowers

an Early Free Agency Winner
Joe Burrow

Can a Healthy Joe Burrow Challenge for QB1?
Amon-Ra St. Brown

Is Amon-Ra St. Brown the Safest Pick in Fantasy?
Xavier Worthy

Dynasty Value Continues to Tumble
Andrei Iosivas

Overshadowed by Two Stud Receivers in Cincy
Jaylen Wright

a Handcuff Option With Upside Going into Year 3
Tyjae Spears

Figures to be in Backup Pass-Catching Role Again in 2026
Tyler Shough

Looking to Build on Encouraging Close to 2025
Karl-Anthony Towns

Rejoins Knicks Lineup Sunday
Marcelo Mayer

Scratched With Left-Knee Soreness
Zach Neto

Tests Come Back Negative, Dealing With Sprained Hand
Ausar Thompson

Returns to Action Sunday
NFL

Emmett Johnson Could Develop into a Three-Down Workhorse in the NFL
Isaiah Hartenstein

Cleared to Return Sunday
NFL

Does Jordyn Tyson Carry Future WR1 Upside?
Anthony Edwards

Available Sunday
Christopher Bell

Looking for Redemption, Wins Pole at Las Vegas
Denny Hamlin

Should Contend for Another Vegas Win
Chase Briscoe

Qualifies 18th Despite Toyota Dominating at Las Vegas
Chase Elliott

May Fly Under the Radar at Las Vegas
De'Anthony Melton

Held Out Sunday Versus New York
NASCAR

Ross Chastian Has Been As Solid As They Come at Las Vegas
Ty Gibbs

Could Ty Gibbs Finally Break Through With a Win at Las Vegas?
Kristaps Porzingis

Won't Play Sunday Versus Knicks
Brad Keselowski

a Solid DFS Pick at Las Vegas
Kevin Porter Jr.

Sidelined Sunday Versus Pacers
Jarrett Allen

to Miss Fifth Straight Game Sunday
Kyle Filipowski

to Sit Sunday for Rest
Francisco Lindor

is Making Spring Debut on Sunday
Carter Verhaeghe

Anton Lundell Expected to Return Sunday
Kyle Larson

Should Kyle Larson be Considered A Favorite for Las Vegas?
Sam Bennett

Considered Day-to-Day
William Byron

Could Compete for a Top-Five Finish at Las Vegas
Sam Reinhart

Not Traveling on Four-Game Road Trip
Ryan Blaney

Is Ryan Blaney Worth Rostering in Tournament DFS Lineups for Las Vegas?
Michael Rasmussen

Ruled Out for One Week
Tyler Reddick

Could Continue his Top-10 Streak at Las Vegas
Declan Carlile

to Miss 4-5 Weeks
Joey Logano

Should DFS Managers Underestimate Joey Logano for Las Vegas?
Igor Chernyshov

Exits Early Due to Injury Saturday
Chris Buescher

Is Chris Buescher Worth Rostering For Las Vegas DFS Lineups?
NASCAR

Bubba Wallace is A Risky DFS Option Who Could Pay Off at Las Vegas
Josh Berry

Has Plenty of Upside for Las Vegas DFS Lineups
Ryan Preece

Scores his First Las Vegas Top-10 Starting Spot in Qualifying
Justin Allgaier

Will Fill In for an Injured Alex Bowman at Las Vegas
Nico Hischier

has Four-Point Performance on Saturday
Seiya Suzuki

Leaves WBC Game on Saturday With Right-Knee Discomfort
Macklin Celebrini

Continues to Dominate With Three Points
Anze Kopitar

Becomes All-Time Leading Scorer for Kings
Linus Ullmark

Posts Shutout Against Ducks
Zach Neto

is Removed After Suffering Hand Injury
TB

Nicholas Paul Rejoins Lightning Lineup
Cole Caufield

Cleared to Play Saturday
Joe Ryan

Won't Pitch in the World Baseball Classic
Zack Wheeler

Throws First Live BP Session on Saturday
Merrill Kelly

Expected to Open Season on the Injured List
Kevin Gausman

Named Toronto's Opening Day Starter
Kyle Stowers

Back in Grapefruit League Lineup
Francisco Lindor

Takes Full Batting Practice on Friday
Brandon Woodruff

Still TBD for Opening Day
Trevor Rogers

to Start on Opening Day for Orioles
Kevin Vallejos

Looks To Remain Undefeated In The UFC
Josh Emmett

In Dire Need Of Victory
Gillian Robertson

A Favorite At UFC Vegas 114
Amanda Lemos

Set For Co-Main Event
Oumar Sy

Looks To Win Back-To-Back Fights
Ion Cutelaba

Looks To Get Back In The Win Column
Blake Snell

Around Six Weeks From Being Fully Built Up
Zack Wheeler

to Face Hitters in Live Batting Practice on Saturday
Gerrit Cole

Could Pitch in a Spring Game Next Week
Hideki Matsuyama

Brings Strong Course History to TPC Sawgrass
Adam Scott

in Strong Form Ahead of The Players
Rickie Fowler

on Quite the Run Heading to TPC Sawgrass
Sepp Straka

Needs to Forget What Happened Sunday at Bay Hill
Jordan Spieth

an Enigma Heading to The Players Championship
Justin Rose

Trying to Pick Up the Pieces in Florida
Maverick McNealy

Bounces Back at Arnold Palmer Invitational
Brooks Koepka

Continues His Florida Swing With Some Momentum
Nicolai Hojgaard

in Strong Form Ahead of The Players
Robert MacIntyre

a Volatile Option at The Players
Matt Fitzpatrick

Looks to Return to Top Form at The Players
Sam Burns

a High-Risk, High-Reward Option at The Players
Keegan Bradley

Hard to Trust at The Players
Xander Schauffele

Rounding into Form Heading to Players Championship
Rory McIlroy

Set to Return at Players Championship to Defend Title
Jake Knapp

Set to Return at Players Championship
Viktor Hovland

Continues Strong Start to 2026 Season
Rasmus Hojgaard

Looking for Bounce-Back at Players Championship
Tommy Fleetwood

Will Need to Find Putter to Compete at Players Championship
Akshay Bhatia

Continues Improving Heading to Players Championship
Justin Thomas

Continues Competitive Return at The Players Championship
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF