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DraftKings Daily Fantasy Baseball Picks (5/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on May 21, 2018. Adam Meyer's MLB DFS analysis and sleepers for building optimal DFS rosters.

It's a short nine-game slate on Monday. Two games have an over/under of at least nine total runs. Five teams are heavy favorites (-185): STL, MIN, NYY, LAD, and WSH. However, while you would think pitching would be loaded, the player pool isn't elite.
On a positive note, weather shouldn't be an issue for Monday. The weekend was full of rain and caused headaches for us all.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @CharlieSideHstl.

DraftKings Starting Pitchers

Walker Buehler, LAD (vs. COL) - $9,300

The MLB team with the lowest runs scored in 2018 was able to produce four earned runs against Buehler in his last start (@ MIA). While that news is somewhat alarming, Buehler still managed to strike out seven batters, continuing his streak of at least five Ks per appearance this season. The Rockies are next for Buehler. Colorado has struck out the seventh-most times this season (426). The Rockies are also 27th in team wOBA against right-handed pitchers (.294). From a Vegas point-of-view, the COL/LAD matchup has the lowest over/under on the slate (seven total runs) and the Dodgers are one of the strongest favorites of the ticket (-180). Both odds are in favor of Buehler.

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Jose Berrios, MIN (vs. DET) - $8,500

It’s a mixed bag when it comes to Berrios and his stat lines. He’s been known to strike out 11 batters in a game, or strikeout none. He’s produced three shutouts in 2018, and allowed five earned runs in three starts this year. However, on a slate this small, without strong pitching prospects, I’d roll the dice on Berrios. His opponent, the Tigers, are 26th in team wOBA against righties (.295) and Vegas has given Minnesota the strongest odds to win on Monday (-200).

 

DraftKings Infielders

C - Gary Sanchez, NYY (@ TEX) - $4,800

After an amazing 4-for-5 performance where Sanchez smacked two home runs in Kansas City, he was given the day off. Now, he’ll look to return to action and continue his hot streak. In the past week, Sanchez is 5-for-11 (.455) with two doubles and two home runs. Sanchez is also third on the team in ISO against right-handed pitchers (.262).

1B - Trey Mancini, BAL (@ CWS) - $3,800

I wanted to wait and see who got the nod for some lineups before I locked in my post for Monday. First base can always be a crucial spot to build, when adding power-hitters to your DFS lineup. I tend to lean towards home running hitting options in this position. Mancini is only 2-for-11 (.111) in the past week, but he's homered three times in the last 10 games. Also, his Orioles are projected to score 4.9 runs (fourth-most) against the White Sox.

2B - Brian Dozier, MIN (vs. DET) - $3,900

Here’s another cold bat that you may not be thrilled with, at first. Dozier is 1-for-21 (.048) in the past week, but his proficiency against lefties is still profitable to the DFS community. He leads the team with a .280 ISO against left-handed pitchers (since 2017). When you get a combination of high ISO, with a leadoff hitter (high in the order), and a reasonable price tag you add them to your DK roster.

3B - Anthony Rendon, WSH (vs. SD) - $3,800

Sure, if you add Rendon with the past two selections you get 3-for-44 (.068) in the last seven days. Rendon is 1-for-12 (.083) in the past week. However, all three are solid selections against southpaws. Rendon leads the Nationals with a .320 ISO against left-handed pitchers.

SS - Didi Gregorius, NYY (@ TEX) - $3,900

I swear these are my suggestions for Monday and not an All-Star team of struggling batters. Gregorius is oh-fer in the past week (0-for-7), but again, the ISO doesn't lie. Even with his recent slump, Gregorius still owns a solid ISO against right-handed pitchers since 2017 (.246). Hopefully, this minor rest (hasn't played since Friday) is enough to wake up his bat and return him to his April numbers (.330 AVG, 10 HR, and 30 RBI).

DraftKings Outfielders

Tommy Pham, STL (vs. KC) - $4,600

The Cardinals have the third-highest implied run total for the Monday slate (5.1 runs). Compared to the previously mentioned bats, Pham is phenomenal. He's batting .280 (7-for-25) with one home run and one double in the past week. He's also tallied at least two hits in three of the past five games. Pham has also produced a .306 AVG against right-handed pitchers this season. His .207 ISO against righties also adds to his case.

Aaron Hicks, NYY (@ TEX) - $3,800

Sometimes you need to be creative when adding players from lineups with high implied run totals. While some DFS players will flock to Aaron Judge and Giancarlo Stanton, we need to pivot to cheaper options, like Hicks. His .205 ISO against righties is only seventh-best on New York, but it's in the range we like to use (.200 or better). Hicks is hitting .467 (7-for-15) with one triple and one home run in the past week.

Marcell Ozuna, STL (vs. KC) - $3,300

Ozuna has gone hitless in his last five games, but he still leads the Cardinals with a .226 ISO against right-handed pitchers. As I mentioned in Pham's write-up, St. Louis has the third-highest implied run total on the board. So, gathering as many hitters from the Cardinals is a wise decision. Ozuna's price tag fits the bill for our circumstances.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

A.J. Brown

Continues Dominant Stretch With 100 Yards in Monday Night Loss
Saquon Barkley

Rips Off Long Touchdown Run in Monday Night Loss
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
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to Become Full-Time DH in 2026?
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Ranger Suárez

Orioles Interested in Signing Ranger Suarez
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Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
Riley Leonard

"Week-to-Week" With Strained Knee
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Patriots-Ravens Week 16 Game Flexed to Sunday Night Football
Omarion Hampton

Making his Return on Monday Night
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Heisman Trophy Finalists Announced on Monday
Justin Herbert

Officially Active Against Eagles
Indianapolis Colts

Colts Bringing Philip Rivers in for a Workout
Justin Herbert

Expected to Start on Monday Night
Trey Benson

Cardinals Could Hold Trey Benson Out Another Week
Keegan Murray

Available on Monday
Anthony Edwards

Set to Suit Up Monday
Jack Roslovic

Not Close to Returning
Dennis Schröder

Dennis Schroder Sidelined Again on Monday
Jake Walman

to Miss at Least Two More Weeks
Berkly Catton

Out Week-to-Week
Franz Wagner

Likely to Miss 2-4 Weeks
Nils Hoglander

Set for Season Debut Monday
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Misses Second Straight Game
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Out Indefinitely
Brayden Point

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Anthony Hill Jr. Declaring for 2026 NFL Draft
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Ryan Walters a Candidate for Tennessee Defensive Coordinator Job?
Trey Hendrickson

Set for Core-Muscle Surgery, Expected to Miss Around Six Weeks
Drake London

Considered Day-to-Day Going into Thursday Night
Jayden Daniels

No Long-Term Concerns for Jayden Daniels
Zach Ertz

MRI Confirms Season-Ending Torn ACL for Zach Ertz
Tee Higgins

Back in the Concussion Protocol
Riley Leonard

Week 15 Status Uncertain Due to Knee Injury
Mike Evans

Could Return on Thursday Night
De'Von Achane

May Require Rest This Week
Daniel Jones

' Season Over With Torn Achilles
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

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Jordan Spieth

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Shedeur Sanders

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Hideki Matsuyama

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Tennessee Fires Defensive Coordinator Tim Banks
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Jordan Poole

Remains Sidelined on Monday
Merab Dvalishvili

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Herbert Jones

Tagged as Questionable Against Spurs
Petr Yan

Reclaims Bantamweight Title
CeeDee Lamb

Progressing Well After Concussion
Stephon Castle

has a Chance to Return on Monday
Alexandre Pantoja

Era Ends With Gruesome Injury
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Becomes Second-Youngest UFC Champion
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Iffy for Monday Night
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Payton Talbott Retires Henry Cejudo
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Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
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Keegan Murray

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Defeats Rangers Sunday
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Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

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Kyle Schwarber

Pirates Make Four-Year Offer to Kyle Schwarber
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Mississippi State, Rice Accept Bowl Bids as 5-7 Teams
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Auburn, Florida State, Baylor Among Teams to Decline Bowl Bids
Paul George

Available on Sunday Evening
Joel Embiid

Available Against Lakers
Lauri Markkanen

Ruled Out Versus OKC
Jimmy Butler III

Officially Active on Sunday Night
CFB

Rob Aurich Set to Become Nebraska's Defensive Coordinator
LeBron James

Available Versus Philadelphia
MON

Samuel Montembeault Ruled Out for Sunday
Carter Hart

Available Against Rangers Sunday
Ryan Leonard

to Miss "Extended Period of Time"
John Carlson

a Game-Time Decision Sunday
Jordan Kyrou

Unavailable Against Canadiens
Matt Duchene

Set to Return Against Penguins
Pyotr Kochetkov

Back for Hurricanes Sunday
CFB

Notre Dame Opting Out of Postseason Amid College Football Playoff Exclusion
Karl-Anthony Towns

Ruled Out Against Orlando
Draymond Green

Remains on the Shelf Versus Chicago
Jimmy Butler III

Expected to Return on Sunday
Immanuel Quickley

Now Probable Versus Boston
Shai Gilgeous-Alexander

Will Miss First Game of the Year on Sunday
Joel Embiid

Upgraded to Probable Against Lakers
CFB

Kendal Briles a Candidate for South Carolina Offensive Coordinator Job
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James Madison Playoff-Bound After Duke Wins ACC Title?
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Notre Dame, Miami, Alabama on College Football Playoff Bubble
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Harry Ford

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Cody Bellinger

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MacKenzie Gore

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Petr Yan

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Merab Dvalishvili

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Alexandre Pantoja

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Looks To Win Back-To-Back Fights
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Searches For His Third Win In A Row
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Henry Cejudo

Set For His Retirement Fight
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Looks To Extend His Win Streak
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Emmett Johnson Leaving Nebraska for 2026 NFL Draft
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Jam Miller Unlikely to Play in SEC Title Game
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Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

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Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
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Billy Napier Finalizing Deal to Become James Madison's New Head Coach
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RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP