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DraftKings Daily Fantasy Baseball Picks (5/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on May 21, 2018. Adam Meyer's MLB DFS analysis and sleepers for building optimal DFS rosters.

It's a short nine-game slate on Monday. Two games have an over/under of at least nine total runs. Five teams are heavy favorites (-185): STL, MIN, NYY, LAD, and WSH. However, while you would think pitching would be loaded, the player pool isn't elite.
On a positive note, weather shouldn't be an issue for Monday. The weekend was full of rain and caused headaches for us all.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @CharlieSideHstl.

DraftKings Starting Pitchers

Walker Buehler, LAD (vs. COL) - $9,300

The MLB team with the lowest runs scored in 2018 was able to produce four earned runs against Buehler in his last start (@ MIA). While that news is somewhat alarming, Buehler still managed to strike out seven batters, continuing his streak of at least five Ks per appearance this season. The Rockies are next for Buehler. Colorado has struck out the seventh-most times this season (426). The Rockies are also 27th in team wOBA against right-handed pitchers (.294). From a Vegas point-of-view, the COL/LAD matchup has the lowest over/under on the slate (seven total runs) and the Dodgers are one of the strongest favorites of the ticket (-180). Both odds are in favor of Buehler.

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Jose Berrios, MIN (vs. DET) - $8,500

It’s a mixed bag when it comes to Berrios and his stat lines. He’s been known to strike out 11 batters in a game, or strikeout none. He’s produced three shutouts in 2018, and allowed five earned runs in three starts this year. However, on a slate this small, without strong pitching prospects, I’d roll the dice on Berrios. His opponent, the Tigers, are 26th in team wOBA against righties (.295) and Vegas has given Minnesota the strongest odds to win on Monday (-200).

 

DraftKings Infielders

C - Gary Sanchez, NYY (@ TEX) - $4,800

After an amazing 4-for-5 performance where Sanchez smacked two home runs in Kansas City, he was given the day off. Now, he’ll look to return to action and continue his hot streak. In the past week, Sanchez is 5-for-11 (.455) with two doubles and two home runs. Sanchez is also third on the team in ISO against right-handed pitchers (.262).

1B - Trey Mancini, BAL (@ CWS) - $3,800

I wanted to wait and see who got the nod for some lineups before I locked in my post for Monday. First base can always be a crucial spot to build, when adding power-hitters to your DFS lineup. I tend to lean towards home running hitting options in this position. Mancini is only 2-for-11 (.111) in the past week, but he's homered three times in the last 10 games. Also, his Orioles are projected to score 4.9 runs (fourth-most) against the White Sox.

2B - Brian Dozier, MIN (vs. DET) - $3,900

Here’s another cold bat that you may not be thrilled with, at first. Dozier is 1-for-21 (.048) in the past week, but his proficiency against lefties is still profitable to the DFS community. He leads the team with a .280 ISO against left-handed pitchers (since 2017). When you get a combination of high ISO, with a leadoff hitter (high in the order), and a reasonable price tag you add them to your DK roster.

3B - Anthony Rendon, WSH (vs. SD) - $3,800

Sure, if you add Rendon with the past two selections you get 3-for-44 (.068) in the last seven days. Rendon is 1-for-12 (.083) in the past week. However, all three are solid selections against southpaws. Rendon leads the Nationals with a .320 ISO against left-handed pitchers.

SS - Didi Gregorius, NYY (@ TEX) - $3,900

I swear these are my suggestions for Monday and not an All-Star team of struggling batters. Gregorius is oh-fer in the past week (0-for-7), but again, the ISO doesn't lie. Even with his recent slump, Gregorius still owns a solid ISO against right-handed pitchers since 2017 (.246). Hopefully, this minor rest (hasn't played since Friday) is enough to wake up his bat and return him to his April numbers (.330 AVG, 10 HR, and 30 RBI).

DraftKings Outfielders

Tommy Pham, STL (vs. KC) - $4,600

The Cardinals have the third-highest implied run total for the Monday slate (5.1 runs). Compared to the previously mentioned bats, Pham is phenomenal. He's batting .280 (7-for-25) with one home run and one double in the past week. He's also tallied at least two hits in three of the past five games. Pham has also produced a .306 AVG against right-handed pitchers this season. His .207 ISO against righties also adds to his case.

Aaron Hicks, NYY (@ TEX) - $3,800

Sometimes you need to be creative when adding players from lineups with high implied run totals. While some DFS players will flock to Aaron Judge and Giancarlo Stanton, we need to pivot to cheaper options, like Hicks. His .205 ISO against righties is only seventh-best on New York, but it's in the range we like to use (.200 or better). Hicks is hitting .467 (7-for-15) with one triple and one home run in the past week.

Marcell Ozuna, STL (vs. KC) - $3,300

Ozuna has gone hitless in his last five games, but he still leads the Cardinals with a .226 ISO against right-handed pitchers. As I mentioned in Pham's write-up, St. Louis has the third-highest implied run total on the board. So, gathering as many hitters from the Cardinals is a wise decision. Ozuna's price tag fits the bill for our circumstances.

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Ludvig Aberg

Making Season Debut at American Express
Ryan Gerard

Heads to PGA West With Momentum After Strong Week in Hawaii
Naz Reid

Holds Questionable Tag for Tuesday
Rudy Gobert

is Cleared for Tuesday's Game
Christian Braun

to Remain Out on Tuesday
Ron Holland II

is Available to Play on Monday
Joel Embiid

Slated to Suit Up Monday
Miami Dolphins

Dolphins Expected to Hire Jeff Hafley as Next Head Coach
Day'Ron Sharpe

Ruled Out on Monday
Jalen Green

to Return on Tuesday
Draymond Green

Ruled Out for Monday's Game
Egor Demin

Ruled Out on Monday
Ondrej Palat

Ready to Face Flames
Devin Booker

Active Against Nets
Chris Kreider

Returns From Two-Game Absence Monday
Corey Perry

Back With Kings
Paul George

Sidelined on Monday
Bobby Brink

Available Monday Night
William Nylander

Misses Second Straight Game Monday
Draymond Green

Downgraded to Questionable on Monday
Kiefer Sherwood

Sharks Pick Up Kiefer Sherwood From Canucks
Matthew Tkachuk

Set for Season Debut Monday
Sepp Straka

Eyes Repeat At The American Express
Si Woo Kim

Poised To Contend At The American Express
Zach Charbonnet

has Torn ACL
Zach Charbonnet

Needs Knee Surgery, Out for Rest of Playoffs
Tennessee Titans

Mike McCarthy a Finalist for Titans Head-Coaching Job?
Colston Loveland

Suffers Concussion in Divisional Round Loss
Kyren Williams

Scores Two Touchdowns in Divisional Round Win
Buffalo Bills

Bills Fire Head Coach Sean McDermott
De'Anthony Melton

Out for Front End of Back-to-Back
Tom Wilson

May Return Monday
Zaccharie Risacher

to Miss Another Game vs. Bucks
Henri Jokiharju

Moved to Non-Roster List
Daniel Gafford

Remains Out Monday Against New York
P.J. Washington

Out Again vs. Knicks
Frank Nazar

Returns to Practice
Oskar Sundqvist

Suffers Skate Cut Sunday
Sam Merrill

Still Out vs. Thunder
Kasperi Kapanen

Considered Day-to-Day
Jalen Williams

Ruled Out Monday with Hamstring Strain
Zach Whitecloud

Joins Flames
Isaiah Hartenstein

Ruled Out Again vs. Cavaliers
Rasmus Andersson

Moves to Vegas
Kristaps Porzingis

to Miss Sixth Straight Game on Monday
Aaron Nesmith

Bennedict Mathurin Out Again, Aaron Nesmith Available vs. 76ers
Carson Soucy

Expected Back on Monday
Teuvo Teravainen

to Remain Out Monday
Matthew Tkachuk

"Close" to Season Debut
Rodrigo Abols

Flyers Place Rodrigo Abols on Injured Reserve
Alex Lyon

Practices on Sunday
Rhamondre Stevenson

Returns in Sunday's AFC Divisional Round Game
Josh Norris

Out Week-to-Week
Dylan Holloway

Set to Return Sunday
Ha-Seong Kim

has Finger Surgery, Out 4-5 Months
Rhamondre Stevenson

Questionable to Return on Sunday With Eye Injury
Woody Marks

Returns Following Brief Exit on Sunday
Dalton Schultz

Won't Return in Sunday's AFC Divisional Round Game
Aaron Rodgers

Steelers Open to Aaron Rodgers Returning in 2026?
Jarrett Stidham

to Start AFC Championship Game
Zach Charbonnet

Questionable to Return Against 49ers
Atlanta Falcons

Falcons Hiring Kevin Stefanski as Head Coach
Bo Nix

Suffers Broken Bone in Ankle, Done for Playoffs
Green Bay Packers

Packers Sign Head Coach Matt LaFleur to Multi-Year Extension
Ricky Pearsall

Active for Divisional Round
Sam Darnold

Officially Active for Saturday's Divisional Round Game vs. 49ers
Pat Bryant

Won't Return on Saturday, Ruled Out with a Concussion
New York Giants

John Harbaugh, Giants Finalize Five-Year Deal
CFB

Darian Mensah Entering Transfer Portal
J.T. Realmuto

Signs Three-Year Deal to Return to Phillies
Bo Bichette

Agrees to Three-Year Contract With Mets
CFB

Weber State Signs former Ohio State, Cal Quarterback Devin Brown
Bo Bichette

Phillies the "Overwhelming" Favorite to Sign Bo Bichette
Josh Lowe

Angels Acquire Josh Lowe in Three-Team Trade
Kyle Tucker

Signs Four-Year Contract With Dodgers
Clayton Kershaw

to Pitch for Team USA in World Baseball Classic
CFB

Auburn, Ohio State the Lead Suitors for Kyle Parker
CFB

Oregon QB Transfer Bryson Beaver Linked to Georgia, Kentucky
CFB

Jake Merklinger Commits to UConn
Ben Griffin

Looks To Stay Hot In 2026
Ranger Suárez

Ranger Suarez Agrees to Five-Year Deal With Red Sox
CFB

Dante Moore Not Entering 2026 NFL Draft, Will Return to Oregon
CFB

FBS Coaches Unanimously Vote to Expand Redshirt Eligibility to Nine Games
CFB

Ohio State Transfer Mylan Graham Signs with Notre Dame
CFB

Caden Durham Withdraws from Transfer Portal, Will Stay at LSU
Jordan Spieth

Perhaps the Most Intriguing Player at Sony Open
Aaron Rai

Looking For Putting Confidence at Waialae Country Club

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP