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5 years agoSan Francisco 49ers running back Matt Breida (ankle) and wide receivers Deebo Samuel (shoulder) and Emmanuel Sanders (ribs) are practicing in full on Thursday. Breida is the big one, as he hasn't played since Nov. 11 against the Seahawks. His return will make it hard to trust anyone in San Fran's backfield, which includes Tevin Coleman and Raheem Mostert. Jeffery Wilson could be a healthy scratch with Breida back in Week 14 to face the Bills in a tough matchup. Samuel and Sanders are good to go as well. Samuel has become the better fantasy wideout over Sanders, but the rookie is still a boom/bust WR3 for fantasy owners in this run-first offense.--Keith Hernandez - RotoBaller
Source: ESPN.com - Nick Wagoner

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